Prosecution Insights
Last updated: October 25, 2026

Sapreme Technologies B V

Technology area: Biotechnology & Pharmaceuticals

15 pending office actions • 8 art units • 10 examiners • 0 of 15 (0%) have an AI response strategy ready • 2 patents granted in the last 365 days

Analysis

Sapreme Technologies B V has 15 pending office actions in Biotechnology & Pharmaceuticals. The portfolio is distributed across 10 distinct examiners and 8 distinct art units, showing that its prosecution workload extends across multiple examination assignments rather than a single channel.

SKOKO III, JOHN JOSEPH is the busiest examiner, with 3 pending matters. That assignment is the largest identified examiner concentration, but it represents only part of the broader portfolio structure. Counsel should maintain a centralized docket while preserving matter-level analysis of claim scope, cited art, and response timing.

The combination of 15 pending actions and 10 examiners creates a coordination issue as well as a substantive prosecution issue. Art-unit-specific review can help identify recurring examination themes, while examiner-specific records can distinguish portfolio-wide concerns from issues limited to particular applications. The 8 art-unit assignments also support tracking whether similar claim strategies are being reviewed under materially different examination practices.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

15
Total Pending OAs
4
Non-Final OAs
10
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 9 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
1
Due this week
3
Due this month
1
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 9 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 7 days (1)Due ≤ 30 days (3)Due ≤ 60 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

5
Hard (33%)
8
Medium (53%)
2
Easy (13%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other1 (7%)
§103 only3 (20%)
§112 only1 (7%)
Double-patenting only1 (7%)
Double-patenting + other5 (33%)
Multi-statute (no §101)4 (27%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

15
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

150 h
Manual time on pending OAs
30 h
Time saved (low, 20%)
52 h
Time saved (mid, 35%)
1.3 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
SKOKO III, JOHN JOSEPH 3 53.0% +55.2%
HUYNH, PHUONG N 2 65.8% +53.6%
CREWS, JARET JAMES 2 43.9% +71.3%
ZARA, JANE J 2 71.0% +16.1%
SU-TOBON, QIWEN NMN 1 66.7% +66.7%
CHONG, KIMBERLY 1 72.3% +13.1%
PUTTLITZ, KARL J 1 69.2% +18.5%
HIBSHMAN, SARAH GRACE 1 38.2% +40.7%
LEE, HOI YAN NMN 1 37.5% +76.2%
BAKSHI, PANCHAM 1 76.7% +30.2%

Hard Cases (5)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
17312193 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS HUYNH, PHUONG N 22d
18012723 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION SKOKO III, JOHN JOSEPH 69d
18564885 CYTOSOLIC DELIVERY OF GENOME EDITING TOOLS SU-TOBON, QIWEN NMN —
18012760 COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND AN ANTIBODY-SAPONIN CONJUGATE HUYNH, PHUONG N —
17312104 Saponin Conjugates BAKSHI, PANCHAM —

Interview Candidates (15)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17415759 DRUG CONJUGATE ZARA, JANE J 30d overdue
18044945 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC CHONG, KIMBERLY 9d overdue
18012694 SAPONIN DERIVATIVES FOR USE IN MEDICINE CREWS, JARET JAMES 1d overdue
17629796 Saponin derivatives with improved therapeutic window CREWS, JARET JAMES 7d
18012710 CONJUGATE OF SAPONIN AND SINGLE-DOMAIN ANTIBODY, PHARMACEUTICAL COMPOSITION COMPRISING SAID CONJUGATE, THERAPEUTIC USE THEREOF PUTTLITZ, KARL J 14d
17312193 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS HUYNH, PHUONG N 22d
18012741 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE SKOKO III, JOHN JOSEPH 26d
17629598 BIOACTIVE SAPONIN LINKED TO A FUNCTIONAL MOIETY LEE, HOI YAN NMN 34d

Top Art Units

Art UnitApps
1643 3
1636 2
1641 2
1691 2
1693 2
1637 2
1646 1
1623 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18564885 CYTOSOLIC DELIVERY OF GENOME EDITING TOOLS SU-TOBON, QIWEN NMN 1636 §101§102§103§112DP Non-Final OA — Pending Nov 28, 2023
18044945 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC CHONG, KIMBERLY 1636 §103§112DP Final Rejection 9d overdue Pending Mar 10, 2023
18012710 CONJUGATE OF SAPONIN AND SINGLE-DOMAIN ANTIBODY, PHARMACEUTICAL COMPOSITION COMPRISING SAID CONJUGATE, THERAPEUTIC USE THEREOF PUTTLITZ, KARL J 1646 DP Final Rejection 14d Pending Dec 23, 2022
18012741 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE SKOKO III, JOHN JOSEPH 1643 §103Other Final Rejection 26d Pending Dec 23, 2022
18012760 COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND AN ANTIBODY-SAPONIN CONJUGATE HUYNH, PHUONG N 1641 §103§112Other Final Rejection — Pending Dec 23, 2022
18012694 SAPONIN DERIVATIVES FOR USE IN MEDICINE CREWS, JARET JAMES 1691 §103 Final Rejection 1d overdue Pending Dec 23, 2022
18012791 HYDRAZONE-BASED SAPONIN DERIVATIVES HIBSHMAN, SARAH GRACE 1693 §103§112DP Non-Final OA — Pending Dec 23, 2022
18012769 CONJUGATE OF GALNAC AND SAPONIN, THERAPEUTIC COMPOSITION COMPRISING SAID CONJUGATE AND A GALNAC-OLIGONUCLEOTIDE CONJUGATE ZARA, JANE J 1637 §112DP Non-Final OA — Pending Dec 23, 2022
18012754 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE SKOKO III, JOHN JOSEPH 1643 §103§112DP Non-Final OA — Pending Dec 23, 2022
18012723 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION SKOKO III, JOHN JOSEPH 1643 §103§112Other Final Rejection 69d Pending Dec 23, 2022
17629796 Saponin derivatives with improved therapeutic window CREWS, JARET JAMES 1691 §112Other Final Rejection 7d Pending Jan 25, 2022
17629598 BIOACTIVE SAPONIN LINKED TO A FUNCTIONAL MOIETY LEE, HOI YAN NMN 1693 §103Other Final Rejection 34d Pending Jan 24, 2022
17415759 DRUG CONJUGATE ZARA, JANE J 1637 §103§112DP Final Rejection 30d overdue Pending Jun 18, 2021
17312104 Saponin Conjugates BAKSHI, PANCHAM 1623 §102§112 Non-Final OA — Pending Jun 09, 2021
17312193 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS HUYNH, PHUONG N 1641 §103§112Other Final Rejection 22d Pending Jun 09, 2021

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Frequently Asked Questions

How many pending USPTO office actions does Sapreme Technologies B V have?

Sapreme Technologies B V has 15 pending office actions as of October 2026, spread across 8 art units and 10 examiners.

Which USPTO examiner handles the most Sapreme Technologies B V applications?

John Joseph Skoko III has the most, with 3 of Sapreme Technologies B V's pending office actions.

What technology area are Sapreme Technologies B V's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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