Prosecution Insights
Last updated: October 04, 2026

The Broad Institute Inc.

Technology area: Biotechnology & Pharmaceuticals

8 pending office actions • 8 art units • 8 examiners • 0 of 8 (0%) have an AI response strategy ready • 4 patents granted in the last 365 days

Analysis

The Broad Institute Inc. has 7 pending office actions in the Biotechnology & Pharmaceuticals technology area. These 7 pending office actions are distributed among 7 distinct examiners, ensuring that no two cases are currently being reviewed by the same person. This distribution across 7 distinct examiners indicates a broad exposure to different examination styles within the patent office. For the institute, this means that 7 independent prosecution tracks are being managed simultaneously.

The portfolio shows a high degree of technical specialization, with 7 distinct art units for only 7 pending office actions. HALVORSON, MARK is the busiest examiner with 1 pending office action, a count shared by all other examiners. The fact that each of the 7 pending office actions resides in one of 7 distinct art units suggests that each filing represents a unique technical niche within the biotechnology field. This relationship between 7 pending office actions, 7 distinct examiners, and 7 distinct art units reflects a highly fragmented prosecution landscape. Practitioners must navigate 7 different sets of art unit guidelines and 7 individual examiner preferences to advance these 7 pending office actions.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

8
Total Pending OAs
4
Non-Final OAs
4
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 3 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

0
Overdue
1
Due this week
1
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 3 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Due ≤ 7 days (1)Due ≤ 30 days (1)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

4
Hard (50%)
2
Medium (25%)
2
Easy (25%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other1 (12%)
§103 only2 (25%)
§112 only2 (25%)
Multi-statute (no §101)3 (38%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

8
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

80 h
Manual time on pending OAs
16 h
Time saved (low, 20%)
28 h
Time saved (mid, 35%)
0.7 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
HALVORSON, MARK 1 47.9% +20.7%
BARSKY, JARED 1 50.2% +22.7%
PAGUIO FRISING, MICHELLE F 1 71.1% +39.3%
KOVACH, KARA NICOLE 1 85.7% +100.0%
IVANOVA, SVETLANA M 1 50.9% +51.5%
POPA, ILEANA 1 21.4% +15.1%
LAFAVE, ELIZABETH ROSE 1 62.5% +45.4%
BEHARRY, ZANNA MARIA 1 24.7% +56.4%

Hard Cases (5)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
18446945 COMPOSITIONS FOR DETECTING SECRETION AND METHODS OF USE POPA, ILEANA 26d
18548580 FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS IVANOVA, SVETLANA M 54d
18580579 COMPOSITIONS AND METHODS FOR CHARACTERIZING A COMPLEX BIOLOGICAL SAMPLE KOVACH, KARA NICOLE —
17927112 NUCLEIC ACID ARTIFICIAL MINI-PROTEOME LIBRARIES LAFAVE, ELIZABETH ROSE —
17615579 REPRODUCIBLE BRAIN ORGANOIDS AND METHODS OF MAKING BEHARRY, ZANNA MARIA —

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
19074044 FORMULATIONS FOR NEOPLASIA VACCINES HALVORSON, MARK 5d
18446945 COMPOSITIONS FOR DETECTING SECRETION AND METHODS OF USE POPA, ILEANA 26d
18548580 FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS IVANOVA, SVETLANA M 54d
18622123 GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS FOR TREATING CTNNB1 SYNDROME BARSKY, JARED —
18690382 SUBSTRATES AND BIOMARKERS OF ADAMTS7 PAGUIO FRISING, MICHELLE F —
18580579 COMPOSITIONS AND METHODS FOR CHARACTERIZING A COMPLEX BIOLOGICAL SAMPLE KOVACH, KARA NICOLE —
17927112 NUCLEIC ACID ARTIFICIAL MINI-PROTEOME LIBRARIES LAFAVE, ELIZABETH ROSE —
17615579 REPRODUCIBLE BRAIN ORGANOIDS AND METHODS OF MAKING BEHARRY, ZANNA MARIA —

Top Art Units

Art UnitApps
1646 1
1628 1
1651 1
1681 1
1627 1
1633 1
1684 1
1632 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19074044 FORMULATIONS FOR NEOPLASIA VACCINES HALVORSON, MARK 1646 §112 Final Rejection 5d Pending Mar 07, 2025
18622123 GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS FOR TREATING CTNNB1 SYNDROME BARSKY, JARED 1628 §103 Non-Final OA — Pending Mar 29, 2024
18690382 SUBSTRATES AND BIOMARKERS OF ADAMTS7 PAGUIO FRISING, MICHELLE F 1651 §112 Non-Final OA — Pending Mar 08, 2024
18580579 COMPOSITIONS AND METHODS FOR CHARACTERIZING A COMPLEX BIOLOGICAL SAMPLE KOVACH, KARA NICOLE 1681 §101§103§112 Non-Final OA — Pending Jan 18, 2024
18548580 FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS IVANOVA, SVETLANA M 1627 §102§103§112 Final Rejection 54d Pending Sep 01, 2023
18446945 COMPOSITIONS FOR DETECTING SECRETION AND METHODS OF USE POPA, ILEANA 1633 §103 Final Rejection 26d Pending Aug 09, 2023
17927112 NUCLEIC ACID ARTIFICIAL MINI-PROTEOME LIBRARIES LAFAVE, ELIZABETH ROSE 1684 §103§112 Non-Final OA — Pending Nov 22, 2022
17615579 REPRODUCIBLE BRAIN ORGANOIDS AND METHODS OF MAKING BEHARRY, ZANNA MARIA 1632 §103§112 Final Rejection — Pending Nov 30, 2021

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