Prosecution Insights
Last updated: October 25, 2026

The Children's Hospital of Philadelphia

Technology area: Biotechnology & Pharmaceuticals

22 pending office actions • 15 art units • 21 examiners • 0 of 22 (0%) have an AI response strategy ready • 17 patents granted in the last 365 days

Analysis

The Children's Hospital of Philadelphia has 25 pending office actions in Biotechnology & Pharmaceuticals. The matters span 23 distinct examiners and 17 distinct art units, making the portfolio broadly distributed while also showing repeated assignments within both examination dimensions. The lower examiner and art-unit counts than the office-action count indicate that some examiners and art units handle multiple matters.

MYERS, CARLA J is the busiest examiner, with 2 pending matters. This is the only examiner-level concentration identified in the profile, but it gives counsel a defined opportunity to compare those matters for shared issues, disclosure support, and response strategy.

The scale and distribution favor centralized docket management combined with matter-specific prosecution analysis. Counsel should preserve consistent positions across related technical areas, while adapting claim amendments and arguments to each examiner and art-unit setting.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

22
Total Pending OAs
16
Non-Final OAs
5
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 4 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
0
Due this week
2
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 4 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (2)Due ≤ 30 days (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

11
Hard (50%)
8
Medium (36%)
3
Easy (14%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other3 (14%)
§103 only5 (23%)
§112 only3 (14%)
Double-patenting + other3 (14%)
Multi-statute (no §101)8 (36%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

19
Life Sciences
86% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
3
Mechanical / Eng
14% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

220 h
Manual time on pending OAs
44 h
Time saved (low, 20%)
77 h
Time saved (mid, 35%)
1.9 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
MYERS, CARLA J 2 49.5% +46.0%
AULAKH, CHARANJIT 1 80.7% -14.5%
PARK, HAEJIN S 1 55.1% +38.3%
OLSON, ANDREA STEFFEL 1 62.4% -11.9%
KOSAR, ANDREW D 1 41.9% +31.9%
MATTHEWS, CHRISTINE HOPKINS 1 71.8% +31.4%
MATALKAH, FATIMAH KHALAF 1 55.8% +27.4%
HUDSON, AMY ROSE 1 74.8% +11.7%
CRAIGO, WILLIAM A 1 48.9% +38.1%
VOKES, KATHLEEN PAIGE 1 56.3% +27.5%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18820706 FASORACETAM CRYSTALLINE FORMS AULAKH, CHARANJIT —

Hard Cases (11)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18033627 COMPOSITIONS AND METHODS FOR IN VIVO GENE TRANSFER SHIN, DANA H 37d overdue
18713342 FLAVANOID CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF FOR THE TREATMENT OF MITOCHONDRIAL DISORDERS OLSON, ANDREA STEFFEL —
18497386 METHODS OF DIAGNOSING AND TREATING CONDUCT DISORDER KOSAR, ANDREW D —
18557664 TRANSFER TRAY AND PRIMING CART FOR NEONATAL CANNULATION AND RELATED METHODS MATTHEWS, CHRISTINE HOPKINS —
18557033 ADENO-ASSOCIATED VIRAL VECTORS FOR TRANSDUCTION OF COCHLEA MATALKAH, FATIMAH KHALAF —
18287150 COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF H-ABC LEUKODYSTROPHY HUDSON, AMY ROSE —
18282653 ENEMA ASSIST DEVICE VOKES, KATHLEEN PAIGE —
18550070 COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF BONE MARROW FAILURE DISEASES ASSOCIATED WITH RIBOSOMOPATHIES PERSONS, JENNA L —

Interview Candidates (9)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18766315 METHODS OF IMPROVING MYOCARDIAL PERFORMANCE IN FONTAN PATIENTS USING UDENAFIL COMPOSITIONS PARK, HAEJIN S —
18497386 METHODS OF DIAGNOSING AND TREATING CONDUCT DISORDER KOSAR, ANDREW D —
18557664 TRANSFER TRAY AND PRIMING CART FOR NEONATAL CANNULATION AND RELATED METHODS MATTHEWS, CHRISTINE HOPKINS —
18557033 ADENO-ASSOCIATED VIRAL VECTORS FOR TRANSDUCTION OF COCHLEA MATALKAH, FATIMAH KHALAF —
18287150 COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF H-ABC LEUKODYSTROPHY HUDSON, AMY ROSE —
18553893 ANTIMICROBIAL ELUTING AIRWAY DEVICES CRAIGO, WILLIAM A —
18282653 ENEMA ASSIST DEVICE VOKES, KATHLEEN PAIGE —
18044471 GENETIC ALTERATIONS ASSOCIATED WITH EOSINOPHILIC ESOPHAGITIS AND METHODS OF USE THEREOF FOR THE DIAGNOSIS AND TREATMENT OF DISEASE MYERS, CARLA J —

Top Art Units

Art UnitApps
1635 3
1693 2
3791 2
1636 2
1682 2
1656 2
1621 1
1614 1
1625 1
1638 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18820706 FASORACETAM CRYSTALLINE FORMS AULAKH, CHARANJIT 1621 §102§103§112DP Non-Final OA — Pending Aug 30, 2024
18766315 METHODS OF IMPROVING MYOCARDIAL PERFORMANCE IN FONTAN PATIENTS USING UDENAFIL COMPOSITIONS PARK, HAEJIN S 1614 §112DP Non-Final OA — Pending Jul 08, 2024
18713342 FLAVANOID CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF FOR THE TREATMENT OF MITOCHONDRIAL DISORDERS OLSON, ANDREA STEFFEL 1693 §101§102§103§112DP Non-Final OA — Pending May 24, 2024
18497386 METHODS OF DIAGNOSING AND TREATING CONDUCT DISORDER KOSAR, ANDREW D 1625 §103§112 Non-Final OA — Pending Oct 30, 2023
18557664 TRANSFER TRAY AND PRIMING CART FOR NEONATAL CANNULATION AND RELATED METHODS MATTHEWS, CHRISTINE HOPKINS 3791 §102§103§112 Non-Final OA — Pending Oct 27, 2023
18557033 ADENO-ASSOCIATED VIRAL VECTORS FOR TRANSDUCTION OF COCHLEA MATALKAH, FATIMAH KHALAF 1638 §103§112 Non-Final OA — Pending Oct 24, 2023
18287150 COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF H-ABC LEUKODYSTROPHY HUDSON, AMY ROSE 1636 §102§103§112 Non-Final OA — Pending Oct 16, 2023
18553893 ANTIMICROBIAL ELUTING AIRWAY DEVICES CRAIGO, WILLIAM A 1615 §103 Final Rejection — Pending Oct 04, 2023
18282653 ENEMA ASSIST DEVICE VOKES, KATHLEEN PAIGE 3783 §102§103 Non-Final OA — Pending Sep 18, 2023
18550070 COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF BONE MARROW FAILURE DISEASES ASSOCIATED WITH RIBOSOMOPATHIES PERSONS, JENNA L 1637 §101§102§103§112 Non-Final OA — Pending Sep 11, 2023
18251075 BREATH BIOMARKERS OF SARS-COV-2 IN CHILDREN AND METHODS OF USE THEREOF FOR THE DIAGNOSIS AND TREATMENT OF COVID-19 WEARE, MEREDITH H 3791 §101§103 Non-Final OA — Pending Apr 28, 2023
18033627 COMPOSITIONS AND METHODS FOR IN VIVO GENE TRANSFER SHIN, DANA H 1635 §102§112 Final Rejection 37d overdue Pending Apr 25, 2023
18044471 GENETIC ALTERATIONS ASSOCIATED WITH EOSINOPHILIC ESOPHAGITIS AND METHODS OF USE THEREOF FOR THE DIAGNOSIS AND TREATMENT OF DISEASE MYERS, CARLA J 1682 §112 Non-Final OA — Pending Mar 08, 2023
18176546 Compositions and Methods for Modulating Factor IX Function TSAY, MARSHA M 1656 §103 Non-Final OA 73d overdue Pending Mar 01, 2023
18007407 NOVEL THERAPEUTIC USES OF COMPOUNDS FOR ENHANCING MITOCHONDRIAL FUNCTION AND TREATING MITOCHONDRIAL DISEASES CHO, DAVID H 1693 §103Other Final Rejection 12d Pending Jan 30, 2023
18006975 IN UTERO AND POSTNATAL GENE EDITING AND THERAPY FOR TREATMENT OF MONOGENIC DISEASES, INCLUDING MUCOPOLYSACCHARIDOSIS TYPE 1H AND OTHER DISORDERS MCLEOD, AFRICA MHAIRIE 1635 §102§103§112 Non-Final OA — Pending Jan 26, 2023
17777245 COMPOSITIONS AND METHODS FOR MODULATING FACTOR VIII FUNCTION MCKNIGHT, CIARA A 1656 §103DP Non-Final OA — Pending May 16, 2022
17694841 Viral Vectors for Prophylaxis and Therapy of Hemoglobinopathies MARVICH, MARIA 1634 §112 Non-Final OA — Pending Mar 15, 2022
17641502 COMPOSITIONS COMPRISING RARE GENETIC SEQUENCE VARIANTS ASSOCIATED WITH PULMONARY FUNCTION AND METHODS OF USE THEREOF FOR DIAGNOSIS AND TREATMENT OF ASTHMA IN AFRICAN AMERICAN PATIENTS MYERS, CARLA J 1682 §112 Non-Final OA — Pending Mar 09, 2022
17279542 2' FANA MODIFIED FOXP3 ANTISENSE OLIGONUCLEOTIDES AND METHODS OF USE THEREOF SULLIVAN, STEPHANIE LAUREN 1635 §103§112 Non-Final OA — Pending Mar 24, 2021
17272005 SCALABLE TAGGING OF ENDOGENOUS GENES BY HOMOLOGY-INDEPENDENT INTRON TARGETING REGA, KYLE THOMAS 1636 §103 Final Rejection 16d Pending Feb 26, 2021
16344298 GENE TRANSFER COMPOSITIONS, METHODS AND USES FOR TREATING NEURODEGENERATIVE DISEASES FONTAINHAS, AURORA M 1675 §103Other Final Rejection — Pending Apr 23, 2019

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Frequently Asked Questions

How many pending USPTO office actions does The Children's Hospital of Philadelphia have?

The Children's Hospital of Philadelphia has 22 pending office actions as of October 2026, spread across 15 art units and 21 examiners.

Which USPTO examiner handles the most The Children's Hospital of Philadelphia applications?

Carla J Myers has the most, with 2 of The Children's Hospital of Philadelphia's pending office actions.

What technology area are The Children's Hospital of Philadelphia's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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