Prosecution Insights
Last updated: October 25, 2026

The Cleveland Clinic Foundation

Technology areas: Biotechnology & Pharmaceuticals • Medical Devices & Mechanical Engineering

28 pending office actions • 23 art units • 28 examiners • 0 of 28 (0%) have an AI response strategy ready • 33 patents granted in the last 365 days

Analysis

The Cleveland Clinic Foundation has 29 pending office actions in Biotechnology & Pharmaceuticals. Those matters involve 29 distinct examiners and 24 distinct art units, indicating that the current prosecution workload is spread broadly across examiner assignments and technical classifications rather than concentrated in a small examination group.

PERRY, MONICA L is the busiest examiner, with 1 pending matter. Because the busiest examiner has only 1 matter, the available data does not identify a dominant examiner-level concentration. Counsel may therefore need a distributed docketing approach that tracks separate examiner and art-unit practices across the portfolio.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

28
Total Pending OAs
17
Non-Final OAs
10
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 7 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
1
Due this week
4
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 7 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (2)Due ≤ 7 days (1)Due ≤ 30 days (4)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

16
Hard (57%)
11
Medium (39%)
1
Easy (4%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 only1 (4%)
§101 + other4 (14%)
§103 only7 (25%)
§112 only1 (4%)
Double-patenting + other4 (14%)
Multi-statute (no §101)11 (39%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

15
Life Sciences
54% of docket
1
Information Tech
4% of docket
1
Communications
4% of docket
0
Semiconductors
0% of docket
11
Mechanical / Eng
39% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

280 h
Manual time on pending OAs
56 h
Time saved (low, 20%)
98 h
Time saved (mid, 35%)
2.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
PERRY, MONICA L 1 56.1% +37.3%
SINGH, ESVINDER 1 77.4% +23.2%
NEGRELLIRODRIGUEZ, CHRISTINA 1 89.0% +10.5%
SHENG, CHAO 1 65.0% +26.6%
BOOKER, KELVIN 1 79.1% +6.8%
PATEL, OM 1 58.0% +52.6%
OAKES, JUSTIN MONTGOMERY 1 100.0% +0.0%
MONTANARI, DAVID A 1 64.8% +49.0%
ZHANG, DUAN 1 61.2% +18.9%
CHESTNUT, BARRY A 1 73.9% +6.3%

Hard Cases (16)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17783359 APPARATUS AND METHOD FOR USE OF FLUID FLOW DEVICE LE, QUYNH DAO 31d overdue
18003807 COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION LEE, CHIHYI NMN 6d
18556564 PROTEASE INHIBITORS AND METHODS OF USE BARSKY, JARED 13d
19055951 SYSTEMS AND METHODS FOR USE WITH MRI-GUIDED FOCUSED ULTRASOUND SHENG, CHAO 20d
19262634 HYBRID CONTROL OF A ROBOTIC SYSTEM SINGH, ESVINDER —
19077527 RETRACTOR SYSTEM FOR ABDOMINAL-WALL REPAIR NEGRELLIRODRIGUEZ, CHRISTINA —
18956213 IDENTIFYING PATIENTS FOR INTENSIVE HYPERGLYCEMIA MANAGEMENT BOOKER, KELVIN —
18916290 METHODS FOR SENSING AND ANALYZING IMPACTS AND PERFORMING AN ASSESSMENT PATEL, OM —

Interview Candidates (7)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 7 ordered by deadline are shown.

App #TitleExaminerDue in
19055951 SYSTEMS AND METHODS FOR USE WITH MRI-GUIDED FOCUSED ULTRASOUND SHENG, CHAO 20d
19157779 HEAD FIXATION DEVICE PERRY, MONICA L —
19262634 HYBRID CONTROL OF A ROBOTIC SYSTEM SINGH, ESVINDER —
19077527 RETRACTOR SYSTEM FOR ABDOMINAL-WALL REPAIR NEGRELLIRODRIGUEZ, CHRISTINA —
18916290 METHODS FOR SENSING AND ANALYZING IMPACTS AND PERFORMING AN ASSESSMENT PATEL, OM —
18675612 GENERATING HUMAN PODOCYTE CELLS MONTANARI, DAVID A —
18640197 SYNTHETIC TABULAR NEURAL GENERATOR ZHANG, DUAN —

Top Art Units

Art UnitApps
3797 2
1672 2
1625 2
1628 2
1643 2
3644 1
3657 1
3773 1
2119 1
3791 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19157779 HEAD FIXATION DEVICE PERRY, MONICA L 3644 §112 Non-Final OA — Pending Aug 19, 2025
19262634 HYBRID CONTROL OF A ROBOTIC SYSTEM SINGH, ESVINDER 3657 §103§112Other Non-Final OA — Pending Jul 08, 2025
19077527 RETRACTOR SYSTEM FOR ABDOMINAL-WALL REPAIR NEGRELLIRODRIGUEZ, CHRISTINA 3773 §102§103 Non-Final OA — Pending Mar 12, 2025
19055951 SYSTEMS AND METHODS FOR USE WITH MRI-GUIDED FOCUSED ULTRASOUND SHENG, CHAO 3797 §102§103 Final Rejection 20d Pending Feb 18, 2025
18956213 IDENTIFYING PATIENTS FOR INTENSIVE HYPERGLYCEMIA MANAGEMENT BOOKER, KELVIN 2119 §103§112 Non-Final OA — Pending Nov 22, 2024
18916290 METHODS FOR SENSING AND ANALYZING IMPACTS AND PERFORMING AN ASSESSMENT PATEL, OM 3791 §101§103§112 Non-Final OA — Pending Oct 15, 2024
18891486 SYSTEM AND METHOD FOR DIAGNOSING INFLAMMATORY BOWEL DISEASE STATE AND SEVERITY OAKES, JUSTIN MONTGOMERY 2662 §101§103 Non-Final OA — Pending Sep 20, 2024
18675612 GENERATING HUMAN PODOCYTE CELLS MONTANARI, DAVID A 1632 §101 Non-Final OA — Pending May 28, 2024
18640197 SYNTHETIC TABULAR NEURAL GENERATOR ZHANG, DUAN 3699 §101§102§103§112 Non-Final OA — Pending Apr 19, 2024
18701156 MRNA VACCINE DESIGN VIA THE ALTERATION OF CODON USAGE CHESTNUT, BARRY A 1672 §103§112 Non-Final OA — Pending Apr 12, 2024
18687993 TOPICAL DRUG TREATMENT TO PREVENT OR REDUCE CORNEAL SCARRING OH, TAYLOR V 1625 §103 Non-Final OA — Pending Feb 29, 2024
18392491 SYSTEMS AND METHODS TO IMPROVE SLEEP DISORDERED BREATHING USING CLOSED-LOOP FEEDBACK TEJANI, ANKIT D 3796 §103Other Non-Final OA — Pending Dec 21, 2023
18528348 GENERATING QUIESCENT HEPATIC STELLATE CELLS AND THEIR USE IN LIVER MODELS LARA, CAROLINE MONSERRAT 1633 §102§103§112DP Non-Final OA — Pending Dec 04, 2023
18566802 NON-CONTACT LITHOTRIPSY USING PHOTONIC NANOPARTICLES ARMSTRONG, SUSANNAH SIPPLE 1616 §102§103§112DP Non-Final OA — Pending Dec 04, 2023
18556564 PROTEASE INHIBITORS AND METHODS OF USE BARSKY, JARED 1628 §102§112 Final Rejection 13d Pending Oct 20, 2023
18478684 TREATING DISEASE AND PROMOTING WEIGHT LOSS BY INHIBITING THE TMA/FMO3/TMAO PATHWAY MAHLUM, JONATHAN DAVIS 1625 §103§112DP Non-Final OA — Pending Sep 29, 2023
18275797 MICRO RNA LIVER CANCER MARKERS AND USES THEREOF YU, TIAN NMN 1681 §101§103 Non-Final OA — Pending Aug 03, 2023
18226698 SYSTEM AND METHOD FOR EXTRACTION OF JOINT-SPECIFIC MOVEMENT CAPACITY AND MOTION SIGNATURE FROM IMAGING CELESTINE, NYROBI I 3798 §103 Final Rejection — Pending Jul 26, 2023
18252928 ANTI-CD6 ANTIBODY CONJUGATES FOR TREATING T-CELL MEDIATED DISORDERS AND T-CELL LYMPHOMA/LEUKEMIA CHATTIN, AMY MARIE 1643 §103§112 Final Rejection — Pending May 15, 2023
18252612 POLYMORHPISM DETECTION FOR GLIOBLASTOMA DETECTION AND TREATMENT BUCHANAN, BAILEY CHEYENNE 1682 §103 Final Rejection — Pending May 11, 2023
18111138 PROTECTIVE COVER DANIEL, ANTARIUS S 3783 §103§112 Non-Final OA — Pending Feb 17, 2023
18169293 AMHR2-ED CANCER VACCINE FORMULATIONS DUFFY, BRADLEY 1643 §103DP Final Rejection 23d overdue Pending Feb 15, 2023
18003807 COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION LEE, CHIHYI NMN 1628 §102§103§112Other Non-Final OA 6d Pending Dec 29, 2022
17854597 RADIOPAQUE TISSUE MARKER TALTY, MARIA CHRISTINA 3797 §103 Final Rejection — Pending Jun 30, 2022
17783359 APPARATUS AND METHOD FOR USE OF FLUID FLOW DEVICE LE, QUYNH DAO 3781 §103§112 Final Rejection 31d overdue Pending Jun 08, 2022
17609957 INDUCED HUMAN COLITIC ORGANOIDS ROGERS, ERIC JASON 1638 §103§112 Final Rejection — Pending Nov 09, 2021
17488384 RAPID TEST SYSTEM FOR VIRAL AND BACTERIAL INFECTIONS JADHAO, SAMADHAN JAISING 1672 §103 Final Rejection 12d Pending Sep 29, 2021
17047497 METHODS AND COMPOSITIONS FOR TH9 CELL MEDIATED CANCER TREATMENT ESSEX, LAURA ANN 1675 §103 Non-Final OA 13d Pending Oct 14, 2020

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Frequently Asked Questions

How many pending USPTO office actions does The Cleveland Clinic Foundation have?

The Cleveland Clinic Foundation has 28 pending office actions as of October 2026, spread across 23 art units and 28 examiners.

Which USPTO examiner handles the most The Cleveland Clinic Foundation applications?

Monica L Perry has the most, with 1 of The Cleveland Clinic Foundation's pending office actions.

What technology area are The Cleveland Clinic Foundation's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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