Prosecution Insights
Last updated: May 29, 2026

Examiner: MATALKAH, FATIMAH KHALAF

Tech Center 1600 • Art Units: 1638

This examiner grants 56% of resolved cases

Performance Statistics

56.3%
Allow Rate
-3.7% vs TC avg
71
Total Applications
+11.5%
Interview Lift
1312
Avg Prosecution Days
Based on 32 resolved cases, 2023–2026

Rejection Statute Breakdown

0.8%
§101 Eligibility
3.3%
§102 Novelty
72.4%
§103 Obviousness
7.3%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
17775859 LENTIVIRAL VECTORS IN HEMATOPOIETIC STEM CELLS TO TREAT RECOMBINATION-ACTIVATING GENE 1 (RAG1) SEVERE COMBINED IMMUNODEFICIENCY (SCID) Final Rejection The Regents of the University of California
17904075 ORTHOGONAL SAFETY SWITCHES TO ELIMINATE GENETICALLY ENGINEERED CELLS Non-Final OA The Board of Trustees of the Leland Stanford Junior University
17793287 INDUCIBLE TISSUE CONSTRUCTS AND USES THEREOF Non-Final OA TRUSTEES OF BOSTON UNIVERSITY
17772385 MEDIUM AND METHODS FOR CULTURING ORGANOIDS Final Rejection UNIVERSITY HEALTH NETWORK
17801917 INDUCIBLE SINGLE AAV SYSTEM AND USES THEREOF Final Rejection University of Massachusetts
18564498 BIOENGINEERED DERMAL PAPILLA AND HAIR FOLLICLES AND RELATED PRODUCTS, METHODS AND APPLICATIONS Non-Final OA The University of Hong Kong
17933730 METHOD FOR DIFFERENTIATION OF BRAIN MURAL CELLS FROM HUMAN PLURIPOTENT STEM CELLS Non-Final OA WISCONSIN ALUMNI RESEARCH FOUNDATION
17907171 REPORTER SYSTEM FOR RADIONUCLIDE IMAGING Final Rejection Erasmus University Medical Center Rotterdam
17346630 METHODS TO ELIMINATE CANCER STEM CELLS BY TARGETING CD47 Final Rejection The U.S.A, as represented by the Secretary, Department of Health and Human Services
18566518 CELL COMPOSITION, METHOD FOR PRODUCING CELL COMPOSITION, AND PHARMACEUTICAL COMPOSITION CONTAINING CELL COMPOSITION Non-Final OA KIRIN HOLDINGS KABUSHIKI KAISHA
18564427 VIRAL VECTOR PRODUCTION Non-Final OA pHion Therapeutics Ltd.
17792203 CELLS HAVING HIGH ADAPTABILITY UNDER HYPOXIC CONDITIONS, AND USE THEREOF Non-Final OA TOOLGEN INCORPORATED
17759183 COMPOSITIONS AND METHODS FOR INCREASING OR ENHANCING TRANSDUCTION OF GENE THERAPY VECTORS AND FOR REMOVING OR REDUCING IMMUNOGLOBULINS Non-Final OA SPARK THERAPEUTICS, INC.
18299989 TREATMENT OF NEUROMUSCULAR DISEASES VIA GENE THERAPY THAT EXPRESSES KLOTHO PROTEIN Non-Final OA Fundació Hospital Universitari Vall d’Hebron-Institut de Recerca
17927078 Lentiviral System Non-Final OA Expression Therapeutics, LLC
18011592 VECTOR Non-Final OA The University of Bristol
18007550 RNA Replicon for Versatile and Efficient Gene Expression Non-Final OA TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenber-Universitä Mainz
17759423 SERUM-FREE MEDIUM FOR CULTURING A BOVINE PROGENITOR CELL Non-Final OA Mosa Meat B.V.
17759294 METHOD FOR TRANSDUCING CELLS WITH VIRAL VECTOR Final Rejection CARSGEN THERAPEUTICS CO., LTD.

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