Prosecution Insights
Last updated: October 02, 2026

Examiner: MIDDLETON, DANAYA L

Tech Center 4100 • Art Units: 1618 1643 1646 1674 4100

This examiner grants 48% of resolved cases

Analysis

Danaya L. Middleton has 97 resolved cases in Tech Center 1600 and Art Unit 1618. Her allowance rate is 48.5 percent, and the median days to allowance is 1312. The 97 resolved cases provide the data foundation for these performance statistics and the 1312-day median timeline. These figures define the typical experience for applications in her care.

The interview lift of 49.4 percent is a notable metric, as it exceeds the 48.5 percent allowance rate. This figure indicates that an interview provides a substantial increase in the likelihood of an allowance. For the 97 resolved cases, this 49.4 percent lift highlights that direct interaction is an effective way to navigate the 1312-day median path to a patent grant. The 49.4 percent lift is a strategic data point for any practitioner working in Art Unit 1618. Utilizing interviews may significantly alter the prosecution trajectory for applications assigned to this examiner.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

48.5%
Allow Rate
-11.5% vs TC avg
132
Total Applications
+49.4%
Interview Lift
1312
Avg Prosecution Days
Based on 97 resolved cases, 2023–2026

Rejection Statute Breakdown

5.1%
§101 Eligibility
13.3%
§102 Novelty
21.8%
§103 Obviousness
35.5%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
17383316 METHOD FOR THE EXPRESSION OF AN ANTIBODY-MULTIMER-FUSION Non-Final OA Genentech, Inc.
17642515 IMMUNOACTIVE MICROPARTICLES AND USES THEREOF Final Rejection The Regents of the University of California
17638519 IMPLANTABLE SCAFFOLDS AND USES THEREOF FOR IMMUNOTHERAPY AND OTHER USES Final Rejection The Regents of the University of California
18565306 NOVEL THERAPEUTIC PEPTIDES FOR NEURODEGENERATION Non-Final OA UNIVERSITY OF SOUTHERN CALIFORNIA
18580385 PROTEASE-MEDIATED TARGET SPECIFIC CYTOKINE DELIVERY USING FUSION POLYPEPTIDE Non-Final OA CHUGAI SEIYAKU KABUSHIKI KAISHA
18023038 HETERODIMER FC POLYPEPTIDE Final Rejection Chugai Seiyaku Kabushiki Kaisha
18022342 HETERODIMER FC POLYPEPTIDE Final Rejection Chugai Seiyaku Kabushiki Kaisha
18036620 BIPHASIC SUBCUTANEOUS DOSING REGIMENS FOR ANTI-VLA-4 ANTIBODIES Final Rejection BIOGEN MA INC.
17800345 ANTI- MUC1-SEA ANTIBODIES Non-Final OA Ramot at Tel-Aviv University Ltd.
18327255 HUMAN ANTIBODIES TO TN ANTIGEN Final Rejection Boehringer Ingelheim International GmbH
17425130 WHOLE CELL TUMOR VACCINES AND METHODS OF USE THEROF Final Rejection CHILDREN'S NATIONAL MEDICAL CENTER
18287593 ANTI-TSLP ANTIBODY COMPOSITIONS AND USES THEREOF Non-Final OA AMGEN INC.
17770259 HLA CLASS I SEQUENCE DIVERGENCE AND CANCER THERAPY Non-Final OA Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
18538932 SEQUENTIAL TRANSARTERIAL CHEMOEMBOLIZATION, STEREOTACTIC BODY RADIOTHERAPY, AND IMMUNOTHERAPY (START-FIT) FOR HEPATOCELLULAR CARCINOMA Non-Final OA The University of Hong Kong
17541627 ANTI-CD19 COMBINATION THERAPY Non-Final OA Incyte Corporation
18644528 HUMANIZED ANTI-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF Final Rejection Genzyme Corporation
17632181 TREATMENT OF CANCER WITH A COMBINATION OF AN ANTIBODY THAT BINDS LGR5 AND EGFR AND A TOPOISOMERASE I INHIBITOR Non-Final OA Merus N.V.
17925547 HUMAN IL-15 MUTANT AND USES THEREOF Final Rejection Shandong Simcere Biopharmaceutical Co., Ltd.
18004004 HIGH CONCENTRATION FORMULATION AND USES THEREOF Non-Final OA CSL Innovation Pty Ltd.
18013523 MULTISPECIFIC BINDING PROTEIN OF IMMUNE CELL ENGAGER, PREPARATION THEREFOR AND APPLICATION THEREOF Final Rejection NONA BIOSCIENCES (SUZHOU) CO., LTD.
17040109 METHODS FOR MODULATING INNATE LYMPHOID CELL ACTIVITY, ANTIBODY DRUG CONJUGATES AND USES IN THERAPY Non-Final OA UNIVERSITÉ D'AIX MARSEILLE

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