Prosecution Insights
Last updated: October 04, 2026

Fisherbroyles, LLP - Codexis, Inc.

Technology area: Biotechnology & Pharmaceuticals

11 pending office actions • 2 clients • 10 examiners • 4 art units • 0 of 11 (0%) have an AI response strategy ready

Analysis

FisherBroyles, LLP - Codexis, Inc. specializes in the Biotechnology & Pharmaceuticals technology area. This profile currently manages 8 pending office actions. Across its entire practice, the firm has filed 20473 career applications.

The firm achieves a resolved allowance rate of 75.5 percent. It averages 3.19 office actions per allowance, providing a predictable metric for clients in the biotech space. These figures reflect the firm's established procedures for handling complex life sciences patenting.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=20473 apps, methodology: how we score firms)

75.5%
Allowance Rate
n=20473
+0.47σ
Allowance Rate (norm)
n=20473
3.2
OAs to Allowance
n=11772
-0.19σ
OAs to Allow (norm)
n=11772
1100 days
Time to Allowance
n=11772
+14.7pp
Interview Lift
n=20473
22.0%
RCE Rate
n=20473
1.0%
Appeal Rate
n=20473

Rejection Performance (% of received rejections ultimately overcome)

65.2%
§101 Overcome
n=1526
69.4%
§102 Overcome
n=4992
69.8%
§103 Overcome
n=7880
72.9%
§112 Overcome
n=6359

Specialization & Scale

A61K, A61P, G06F
Top CPC Subclasses
12%
Top-3 CPC Share
n=20473
25
Practitioners
n=20473
818.9
Apps / Practitioner
n=20473

Portfolio Summary

11
Total Pending OAs
10
Non-Final OAs
1
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 1 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

0
Overdue
0
Due this week
0
Due this month
1
Due in next 60 days
0
Due later

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

4
Hard (36%)
4
Medium (36%)
2
Easy (18%)
1
Unknown (9%)

Rejection Statute Mix

BucketCases
§101 + other3 (27%)
§112 only1 (9%)
Double-patenting only1 (9%)
Double-patenting + other4 (36%)
Multi-statute (no §101)1 (9%)
No statute on record1 (9%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

7
Life Sciences
64% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
4
Business / Other
36% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

110 h
Manual time on pending OAs
22 h
Time saved (low, 20%)
38 h
Time saved (mid, 35%)
1.0 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
MEAH, MOHAMMAD Y 2 70.8% +42.7%
EPSTEIN, TODD MATTHEW 1 60.9% +43.4%
HOLLAND, PAUL J 1 57.5% +64.6%
BOWERS, ERIN M 1 54.7% +10.6%
HUTSON, RICHARD G 1 65.1% +53.1%
ROBINSON, HOPE A 1 67.7% +43.1%
GRAY, JESSICA 1 0.0% +0.0%
MCKNIGHT, CIARA A 1 60.8% +38.8%
JONES-FOSTER, ERICA NICOLE 1 48.1% +44.7%
NOAKES, SUZANNE MARIE 1 73.3% +18.2%

Hard Cases (5)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
18516054 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY MCKNIGHT, CIARA A 34d
18660851 RNA POLYMERASE VARIANTS BOWERS, ERIN M —
18661523 ENGINEERED RNA POLYMERASE VARIANTS HUTSON, RICHARD G —
18395294 ENGINEERED RNA LIGASE VARIANTS GRAY, JESSICA —
18485925 ENGINEERED 3-O-KINASE VARIANTS AND METHODS OF USE NOAKES, SUZANNE MARIE —

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18516054 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY MCKNIGHT, CIARA A 34d
18971755 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS EPSTEIN, TODD MATTHEW —
18886292 BIOCATALYSTS FOR EZETIMIBE SYNTHESIS MEAH, MOHAMMAD Y —
18822990 ENGINEERED PANTOTHENATE KINASE VARIANT ENZYMES HOLLAND, PAUL J —
18781007 LOV-D ACYLTRANSFERASE MEDIATED ACYLATION MEAH, MOHAMMAD Y —
18660851 RNA POLYMERASE VARIANTS BOWERS, ERIN M —
18661523 ENGINEERED RNA POLYMERASE VARIANTS HUTSON, RICHARD G —
18638060 ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS ROBINSON, HOPE A —

Client Portfolio (2 clients)

Client (Assignee)Pending OAs
Codexis 9
Codexis Inc. 2

Top Art Units

Art UnitApps
16563
16522
16531
16821

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18971755 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS Codexis, Inc. EPSTEIN, TODD MATTHEW Other Non-Final OA — Pending Dec 06, 2024
18886292 BIOCATALYSTS FOR EZETIMIBE SYNTHESIS Codexis Inc. MEAH, MOHAMMAD Y §112DP Non-Final OA — Pending Sep 16, 2024
18822990 ENGINEERED PANTOTHENATE KINASE VARIANT ENZYMES Codexis, Inc. HOLLAND, PAUL J §112DP Non-Final OA — Pending Sep 03, 2024
18781007 LOV-D ACYLTRANSFERASE MEDIATED ACYLATION Codexis Inc. MEAH, MOHAMMAD Y DP Non-Final OA — Pending Jul 23, 2024
18660851 RNA POLYMERASE VARIANTS Codexis, Inc. BOWERS, ERIN M 1653 §101§102 Non-Final OA — Pending May 10, 2024
18661523 ENGINEERED RNA POLYMERASE VARIANTS Codexis, Inc. HUTSON, RICHARD G 1652 §101§102§103§112 Non-Final OA — Pending May 10, 2024
18638060 ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS Codexis, Inc. ROBINSON, HOPE A 1652 §112 Non-Final OA — Pending Apr 17, 2024
18395294 ENGINEERED RNA LIGASE VARIANTS Codexis, Inc. GRAY, JESSICA 1682 §102§103DP Non-Final OA — Pending Dec 22, 2023
18516054 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY Codexis, Inc. MCKNIGHT, CIARA A 1656 §102§103Other Non-Final OA 34d Pending Nov 21, 2023
18516310 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY Codexis, Inc. JONES-FOSTER, ERICA NICOLE 1656 §102§103§112DP Non-Final OA — Pending Nov 21, 2023
18485925 ENGINEERED 3-O-KINASE VARIANTS AND METHODS OF USE Codexis, Inc. NOAKES, SUZANNE MARIE 1656 §101§102DP Final Rejection — Pending Oct 12, 2023

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