Prosecution Insights
Last updated: October 25, 2026

Grimes & Yvon LLP

Technology area: Biotechnology & Pharmaceuticals

25 pending office actions • 12 clients • 24 examiners • 19 art units • 0 of 25 (0%) have an AI response strategy ready

Analysis

This profile covers Biotechnology & Pharmaceuticals and shows 25 pending office actions. Its 538 career applications provide a recorded historical base for the current workload.

The resolved allowance rate is 68.95%, and the average is 3.61 office actions per allowance. The resolved record indicates allowance in a smaller share of matters than non-allowance, while allowances generally followed several office actions.

For practitioners, the figures support close attention to claim strategy, amendment choices, and response timing. The allowance rate frames the historical outcome challenge, and the action average indicates that matters reaching allowance may require sustained prosecution effort.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=538 apps, methodology: how we score firms)

69.0%
Allowance Rate
n=538
+0.66σ
Allowance Rate (norm)
n=538
3.6
OAs to Allowance
n=171
-0.28σ
OAs to Allow (norm)
n=171
1154 days
Time to Allowance
n=171
+20.5pp
Interview Lift
n=538
33.1%
RCE Rate
n=538
0.0%
Appeal Rate
n=538

Rejection Performance (% of received rejections ultimately overcome)

72.9%
§101 Overcome
n=48
51.0%
§102 Overcome
n=100
53.5%
§103 Overcome
n=157
60.7%
§112 Overcome
n=178

Specialization & Scale

A61K, A61P, C07K
Top CPC Subclasses
56%
Top-3 CPC Share
n=538
3
Practitioners
n=538
179.3
Apps / Practitioner
n=538

Portfolio Summary

25
Total Pending OAs
18
Non-Final OAs
6
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 7 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
1
Due this week
2
Due this month
0
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 7 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (2)Due ≤ 7 days (1)Due ≤ 30 days (2)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

16
Hard (64%)
6
Medium (24%)
3
Easy (12%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other2 (8%)
§103 only5 (20%)
§112 only2 (8%)
Double-patenting only1 (4%)
Double-patenting + other1 (4%)
Multi-statute (no §101)14 (56%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

25
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

250 h
Manual time on pending OAs
50 h
Time saved (low, 20%)
88 h
Time saved (mid, 35%)
2.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
STOICA, ELLY GERALD 2 66.8% +22.6%
BLUMEL, BENJAMIN P 1 70.7% +30.6%
BAUER, NICOLA MARIA 1 58.7% +52.1%
BOECKELMAN, JACOB A 1 34.9% +46.5%
MONTANARI, DAVID A 1 64.8% +49.0%
ABBAS, SYED JARAR 1 25.0% +0.0%
WANG, CHANG YU 1 33.4% +53.7%
YU, HONG 1 31.1% +5.7%
GOLDBERG, JEANINE ANNE 1 45.4% +40.5%
TCHERKASSKAYA, OLGA V 1 55.5% +46.4%

Hard Cases (16)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18066567 METHODS AND COMPOSITIONS FOR THE PRODUCTION OF ADENO-ASSOCIATED VIRUS GONZALES, JOSEPHINE MARIA 69d
17909427 Replication Competent Virus Assay WANG, RUIXUE 69d
18940528 Deamidation Depleted Adeno-Associated Virus Product BLUMEL, BENJAMIN P —
18859396 USE OF LAT1 INHIBITORS TO TREAT OBESITY BAUER, NICOLA MARIA —
18833550 METHOD FOR THE PRODUCTION OF A PLANT EXTRACT BOECKELMAN, JACOB A —
18657524 ENHANCED GENE DELIVERY METHODS MONTANARI, DAVID A —
18707578 IL33 PROTEINS AND METHODS OF USE THEREOF ABBAS, SYED JARAR —
18627010 BLOOD-BASED ASSAY FOR DETECTING TAUOPATHY OR AMYLOIDOGENIC DISEASE WANG, CHANG YU —

Interview Candidates (9)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18411193 Pharmaceutical Composition and Method for Improving Biomechanical Integrity of the Pelvic Floor TCHERKASSKAYA, OLGA V 30d
18940528 Deamidation Depleted Adeno-Associated Virus Product BLUMEL, BENJAMIN P —
18859396 USE OF LAT1 INHIBITORS TO TREAT OBESITY BAUER, NICOLA MARIA —
18833550 METHOD FOR THE PRODUCTION OF A PLANT EXTRACT BOECKELMAN, JACOB A —
18657524 ENHANCED GENE DELIVERY METHODS MONTANARI, DAVID A —
18627010 BLOOD-BASED ASSAY FOR DETECTING TAUOPATHY OR AMYLOIDOGENIC DISEASE WANG, CHANG YU —
18291113 USE OF CIRCULATING CELL-FREE METHYLATED DNA TO DETECT TISSUE DAMAGE GOLDBERG, JEANINE ANNE —
18575804 Method of Administering Anti-HPA-1a Monoclonal Antibody STOICA, ELLY GERALD —

Client Portfolio (12 clients)

Top Art Units

Art UnitApps
16313
16322
16822
16472
16282
16711
16211
16551
16741
16751

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18940528 Deamidation Depleted Adeno-Associated Virus Product Oxford Biomedica (Us) LLC BLUMEL, BENJAMIN P 1671 §102§103§112 Non-Final OA — Pending Nov 07, 2024
18859396 USE OF LAT1 INHIBITORS TO TREAT OBESITY Georgetown University BAUER, NICOLA MARIA 1621 §102§103 Non-Final OA — Pending Oct 23, 2024
18833550 METHOD FOR THE PRODUCTION OF A PLANT EXTRACT Vertanical GmbH BOECKELMAN, JACOB A 1655 §102§103§112 Non-Final OA — Pending Jul 26, 2024
18657524 ENHANCED GENE DELIVERY METHODS Angiocrine Bioscience, Inc. MONTANARI, DAVID A 1632 §103§112 Non-Final OA — Pending May 07, 2024
18707578 IL33 PROTEINS AND METHODS OF USE THEREOF Memorial Sloan Kettering Cancer Center ABBAS, SYED JARAR 1674 §102§112 Non-Final OA — Pending May 04, 2024
18627010 BLOOD-BASED ASSAY FOR DETECTING TAUOPATHY OR AMYLOIDOGENIC DISEASE Janssen Pharmaceutica NV WANG, CHANG YU 1675 §101§102§112DP Non-Final OA — Pending Apr 04, 2024
18622971 Pharmaceutical Composition and Method for Treating or Preventing Candidiasis Fempharma, LLC YU, HONG 1614 §103 Final Rejection 22d Pending Mar 31, 2024
18291113 USE OF CIRCULATING CELL-FREE METHYLATED DNA TO DETECT TISSUE DAMAGE Georgetown University GOLDBERG, JEANINE ANNE 1682 §101§102§103§112 Non-Final OA — Pending Jan 22, 2024
18411193 Pharmaceutical Composition and Method for Improving Biomechanical Integrity of the Pelvic Floor Fempharma, LLC TCHERKASSKAYA, OLGA V 1615 §112 Final Rejection 30d Pending Jan 12, 2024
18575804 Method of Administering Anti-HPA-1a Monoclonal Antibody Rallybio Ipa, LLC STOICA, ELLY GERALD 1647 §102§103§112 Non-Final OA — Pending Dec 29, 2023
18575805 Administration of Anti-HPA-1a Antibodies Rallybio Ipa, LLC STOICA, ELLY GERALD 1647 §103DP Non-Final OA — Pending Dec 29, 2023
18570043 Treatment of Inflammatory Conditions or Diseases Queen Mary University Of London FAUST, AMBER KATHLEEN 1643 §102§103§112 Non-Final OA — Pending Dec 13, 2023
17792557 METHODS AND COMPOSITIONS FOR CANCER IMMUNOTHERAPY Memorial Sloan Kettering Cancer Center LEE, CHIHYI NMN 1628 §103§112 Non-Final OA — Pending Jun 20, 2023
18138058 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF AGE-RELATED MACULAR DEGENERATION Georgetown University BARSKY, JARED 1628 §103 Final Rejection 89d overdue Pending Apr 22, 2023
18249248 INDUCTION OF FERROPTOSIS FOR CANCER THERAPY Memorial Sloan Kettering Cancer Center HUDSON, AMY ROSE 1636 §102§103§112 Non-Final OA — Pending Apr 15, 2023
18041080 CRYOPRESERVED ENDOTHELIAL CELL COMPOSITIONS Angiocrine Bioscience, Inc. ABBOTT, KODYE LEE 1634 §103§112 Non-Final OA — Pending Feb 09, 2023
17924980 METHOD OF TREATMENT OF CANCER OR TUMOUR USWM CT,LLC POPA, ILEANA 1633 §102§103§112Other Non-Final OA — Pending Jan 23, 2023
18003124 ENDOTHELIAL CELLS FOR MITIGATION OF CHEMOTHERAPY-INDUCED TOXICITY Angiocrine Bioscience, Inc. SCHUBERG, LAURA J 1631 §103Other Final Rejection 25d overdue Pending Dec 22, 2022
18011171 Administration of CEBP-Beta Antagonist and Methods of Use Sapience Therapeutics, Inc. STEELE, AMBER D 1658 DP Non-Final OA — Pending Dec 17, 2022
18066567 METHODS AND COMPOSITIONS FOR THE PRODUCTION OF ADENO-ASSOCIATED VIRUS Oxford Biomedica (Us) LLC GONZALES, JOSEPHINE MARIA 1631 §102§103 Non-Final OA 69d Pending Dec 15, 2022
17921606 METHODS FOR ISOLATING AND CULTURING TUMOR CELLS Georgetown University TRAN, KHOA NHAT 1632 §103§112 Non-Final OA — Pending Oct 26, 2022
17909427 Replication Competent Virus Assay Oxford Biomedica (Uk) Limited WANG, RUIXUE 1672 §103§112 Final Rejection 69d Pending Sep 05, 2022
17629378 Enhancing Production of Lentiviral Vectors Oxford Biomedica (Uk) Limited BATES, KEENAN ALEXANDER 1631 §112Other Final Rejection — Pending Jan 22, 2022
17293372 METHOD, SOLUTION AND KIT FOR PREPARING A TISSUE SAMPLE FOR 3D IMAGING The Francis Crick Institute Limited REGLAS, GEORGIANA C 1651 §103 Non-Final OA — Pending May 12, 2021
17196631 METHODS AND COMPOSITIONS FOR DETECTION OF HPV DNA AND DIAGNOSIS AND MONITORING OF HPV-ASSOCIATED CANCERS Memorial Sloan Kettering Cancer Center HANEY, AMANDA MARIE 1682 §103 Non-Final OA 7d Pending Mar 09, 2021

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Frequently Asked Questions

What is Grimes & Yvon LLP's patent allowance rate?

69.0% of resolved applications prosecuted by Grimes & Yvon LLP were allowed, across 538 applications in USPTO records.

How many office actions does Grimes & Yvon LLP average before allowance?

3.61 office actions per allowed application on average.

How many pending office actions does Grimes & Yvon LLP have?

25 pending office actions as of October 2026, for 12 clients, before 24 examiners in 19 art units.

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