Prosecution Insights
Last updated: July 17, 2026

Mbhb - Warf

22 pending office actions • 2 clients • 20 examiners • 15 art units • 0 of 22 (0%) have an AI response strategy ready • 11 patents granted in the last 365 days

Quality Metrics (n=216 apps, methodology: how we score firms)

91.6%
Allowance Rate
n=216
+1.18σ
Allowance Rate (norm)
n=216
5.9
OAs to Allowance
n=98
+0.26σ
OAs to Allow (norm)
n=98
1465 days
Time to Allowance
n=98
+11.2pp
Interview Lift
n=216
67.3%
RCE Rate
n=216
1.3%
Appeal Rate
n=216

Rejection Performance (% of received rejections ultimately overcome)

§101 Overcome
n=7 (min 20)
70.8%
§102 Overcome
n=24
66.7%
§103 Overcome
n=75
84.6%
§112 Overcome
n=39

Specialization & Scale

C12N, A61K, G01N
Top CPC Subclasses
67%
Top-3 CPC Share
n=216
0
Practitioners
n=216
Apps / Practitioner
n=216 (min 20)

Portfolio Summary

22
Total Pending OAs
17
Non-Final OAs
5
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 13 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

8
Overdue
1
Due this week
0
Due this month
3
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 13 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (8)Due ≤ 7 days (1)Due ≤ 60 days (3)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
13
Medium (59%)
5
Easy (23%)
4
Unknown (18%)

Rejection Statute Mix

BucketCases
§103 only12 (55%)
§102 only1 (5%)
§112 only3 (14%)
Double-patenting only2 (9%)
No statute on record4 (18%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

21
Life Sciences
95% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
1
Mechanical / Eng
5% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

220 h
Manual time on pending OAs
44 h
Time saved (low, 20%)
77 h
Time saved (mid, 35%)
1.9 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
STAVROU, CONSTANTINA E 2 42.9% +34.3%
WILSON, MICHAEL C 2 41.5% +17.4%
TAKENAKA, RISA 1 21.1% +100.0%
CHHAY, BONIRATH 1 100.0% +0.0%
SCHUBERG, LAURA J 1 23.9% +37.3%
WEHBE, ANNE MARIE SABRINA 1 57.4% +42.6%
STOICA, ELLY GERALD 1 66.7% +22.7%
NGUYEN, NGHI V 1 53.6% +50.5%
MELCHIOR, JAMES RYLAND 1 61.9% +45.2%
PASQUALINI, HANNA LOUISE 1 40.0% +33.3%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18471422 Compositions and Methods to Enhance Therapeutic Efficacy of Cancer Therapies CHHAY, BONIRATH

Hard Cases (2)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
18463211 REAGENTS AND METHODS FOR PRODUCING ERYTHROMYELOID PROGENITOR CELLS, NK CELLS, AND MEGAKARYOCYTES SCHUBERG, LAURA J 18d overdue
18613041 REAGENTS AND METHODS FOR PROMOTING ARTERIAL ENDOTHELIUM DIFFERENTIATION AND NITRIC OXIDE PRODUCTION TAKENAKA, RISA

Interview Candidates (11)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18463211 REAGENTS AND METHODS FOR PRODUCING ERYTHROMYELOID PROGENITOR CELLS, NK CELLS, AND MEGAKARYOCYTES SCHUBERG, LAURA J 18d overdue
18310510 GENERATING ARTERIAL ENDOTHELIAL CELL POPULATIONS NGUYEN, NGHI V 5d overdue
18057026 Methods for Printing Functional Human Neural Tissue STAVROU, CONSTANTINA E 5d
17352873 PLURIPOTENT STEM CELLS OBTAINED BY NON-VIRAL REPORGRAMMING WILSON, MICHAEL C 33d
17345773 Methods for Cardiac Fibroblast Differentiation of Human Pluripotent Stem Cells WILSON, MICHAEL C 34d
18297417 GENERATING ALLOGENIC ENDOTHELIAL CELL-SEEDED VASCULAR GRAFTS AND METHODS OF USE THEREOF PASQUALINI, HANNA LOUISE 39d
18302636 COMBINATIONAL IMMUNOTHERAPIES USING CAR-M, CAR-NK, CAR-EOS, AND CAR-N CELLS MELCHIOR, JAMES RYLAND 84d
18613041 REAGENTS AND METHODS FOR PROMOTING ARTERIAL ENDOTHELIUM DIFFERENTIATION AND NITRIC OXIDE PRODUCTION TAKENAKA, RISA

Client Portfolio (2 clients)

Top Art Units

Art UnitApps
16533
16313
16322
16752
16382
16451
16341
16181
16441
37741

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18613041 REAGENTS AND METHODS FOR PROMOTING ARTERIAL ENDOTHELIUM DIFFERENTIATION AND NITRIC OXIDE PRODUCTION Wisconsin Alumni Research Foundation TAKENAKA, RISA 1653 §103 Non-Final OA Pending Mar 21, 2024
18471422 Compositions and Methods to Enhance Therapeutic Efficacy of Cancer Therapies Wisconsin Alumni Research Foundation CHHAY, BONIRATH 1645 §103 Non-Final OA Pending Sep 21, 2023
18463211 REAGENTS AND METHODS FOR PRODUCING ERYTHROMYELOID PROGENITOR CELLS, NK CELLS, AND MEGAKARYOCYTES Wisconsin Alumni Research Foundation SCHUBERG, LAURA J 1631 §102 Non-Final OA 18d overdue Pending Sep 07, 2023
18351246 Macrophage Cell Therapy to Treat Orthopedic Injury Wisconsin Alumni Research Foundation WEHBE, ANNE MARIE SABRINA 1634 §112 Non-Final OA Pending Jul 12, 2023
18332457 Fibroblast Activation ImmunoPET for Detection of Fibrosis Activity Wisconsin Alumni Research Foundation STOICA, ELLY GERALD 1618 DP Non-Final OA Pending Jun 09, 2023
18310510 GENERATING ARTERIAL ENDOTHELIAL CELL POPULATIONS Wisconsin Alumni Research Foundation NGUYEN, NGHI V 1653 §103 Non-Final OA 5d overdue Pending May 01, 2023
18302636 COMBINATIONAL IMMUNOTHERAPIES USING CAR-M, CAR-NK, CAR-EOS, AND CAR-N CELLS Wisconsin Alumni Research Foundation MELCHIOR, JAMES RYLAND 1644 §103 Non-Final OA 84d Pending Apr 18, 2023
18297417 GENERATING ALLOGENIC ENDOTHELIAL CELL-SEEDED VASCULAR GRAFTS AND METHODS OF USE THEREOF Wisconsin Alumni Research Foundation PASQUALINI, HANNA LOUISE 3774 §103 Non-Final OA 39d Pending Apr 07, 2023
18296895 Protein Tyrosine Phosphatase 1B Inhibited Neutrophils, Neutrophil-Dendritic Cell Hybrids and Uses Thereof Wisconsin Alumni Research Foundation SHIBUYA, MARK LANCE 1631 Other Non-Final OA 18d overdue Pending Apr 06, 2023
18182850 Using Targeted Radiotherapy (TRT) to Drive Anti-Tumor Immune Response to Immunotherapies Wisconsin Alumni Research Foundation CANELLA, KAREN A 1643 Other Non-Final OA Pending Mar 13, 2023
18094221 T CELL SPECIFIC BIOMARKERS FOR PREDICTING GRAFT-VS-HOST DISEASE AND HEMATOPOIETIC MALIGNANCY RELAPSE FOLLOWING HEMATOPOIETIC STEM CELL TRANSPLANTATION AND TREATMENT THEREOF Wisconsin Alumni Research Foundation GABEL, GAILENE 1678 §103 Non-Final OA 31d overdue Pending Jan 06, 2023
18057026 Methods for Printing Functional Human Neural Tissue Wisconsin Alumni Research Foundation STAVROU, CONSTANTINA E 1632 §103 Final Rejection 5d Pending Nov 18, 2022
17973020 Simplified Compositions and Methods for Generating Neural Stem Cells from Human Pluripotent Stem Cells Wisconsin Alumni Research Foundation DUTT, ADITI 1675 DP Non-Final OA Pending Oct 25, 2022
17863363 LPS Priming of Stromal Cells to Generate LPS-Specific Exosome Educated Macrophages Wisconsin Alumni Research Foundation FOX, ALLISON M 1633 Other Non-Final OA 37d overdue Pending Jul 12, 2022
17545416 METHODS FOR CONTROLLED INDUCTION OF BIOENGINEERED NEUROEPITHELIAL TISSUES AND 3-D NEUROEPITHELIAL TUBES Wisconsin Alumni Research Foundation STAVROU, CONSTANTINA E 1632 §103 Non-Final OA Pending Dec 08, 2021
17352873 PLURIPOTENT STEM CELLS OBTAINED BY NON-VIRAL REPORGRAMMING Wisconsin Alumni Resarch Foundation WILSON, MICHAEL C 1638 §103 Final Rejection 33d Pending Jun 21, 2021
17345773 Methods for Cardiac Fibroblast Differentiation of Human Pluripotent Stem Cells Wisconsin Alumni Research Foundation WILSON, MICHAEL C 1638 §103 Final Rejection 34d Pending Jun 11, 2021
17343647 COMPOSITIONS AND METHODS FOR PRECISE PATTERNING OF POSTERIOR NEUROECTODERM FROM HUMAN PLURIPOTENT STEM CELLS Wisconsin Alumni Research Foundation WILLIAMS, EMMALEE RAE 1653 §103 Final Rejection Pending Jun 09, 2021
17117062 IN VITRO EXPANSION OF DOPAMINERGIC SUBTYPE NEURONAL PROGENITORS DERIVED FROM PLURIPOTENT STEM CELLS Wisconsin Alumni Research Foundation MIANO, JOSEPH PAUL 1631 §103 Non-Final OA Pending Dec 09, 2020
16876353 EFFICIENT, SCALABLE PRODUCTION OF HUMAN RETINAL PROGENITORS IN VITRO Wisconsin Alumni Research Foundation WANG, CHANG YU 1675 §112 Non-Final OA 4d overdue Pending May 18, 2020
16198019 CARDIAC FIBROBLAST-DERIVED EXTRACELLULAR MATRIX AND INJECTABLE FORMULATIONS THEREOF FOR TREATMENT OF ISCHEMIC DISEASE OR INJURY Wisconsin Alumni Research Foundation REYNOLDS, FRED H 1658 Other Final Rejection 3d overdue Pending Nov 21, 2018
16102475 METHODS AND COMPOSITIONS FOR RESISTANCE TO CYST NEMATODE IN PLANTS Wisconsin Alumni Research Foundation ZHENG, LI 1662 §112 Non-Final OA 22d overdue Pending Aug 13, 2018

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