Prosecution Insights
Last updated: October 25, 2026

Sheppard Mullin Richter & Hampton Llp-Ionis Pharm

Technology area: Biotechnology & Pharmaceuticals

5 pending office actions • 2 clients • 5 examiners • 3 art units • 0 of 5 (0%) have an AI response strategy ready • 1 patents granted in the last 365 days

Analysis

Sheppard Mullin Richter & Hampton LLP-Ionis Pharm has 5 pending office actions in Biotechnology & Pharmaceuticals. The record attributes 14771 career applications, a figure that supplies application-history context for this profile.

The resolved allowance rate is 87.12%, and allowed matters averaged 3.19 office actions per allowance. Those measures describe resolved prosecution outcomes and the action activity associated with allowances, respectively. Because the profile is tied to Ionis Pharm and retains the broader application-history figure, practitioners should review the current matters separately from the historical outcome indicators.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=14771 apps, methodology: how we score firms)

87.1%
Allowance Rate
n=14771
+0.56σ
Allowance Rate (norm)
n=14771
3.2
OAs to Allowance
n=8871
-0.24σ
OAs to Allow (norm)
n=8871
925 days
Time to Allowance
n=8871
+6.6pp
Interview Lift
n=14771
27.6%
RCE Rate
n=14771
1.9%
Appeal Rate
n=14771

Rejection Performance (% of received rejections ultimately overcome)

74.7%
§101 Overcome
n=1883
76.4%
§102 Overcome
n=3812
77.9%
§103 Overcome
n=6362
77.4%
§112 Overcome
n=3867

Specialization & Scale

G06F, H04L, G06Q
Top CPC Subclasses
19%
Top-3 CPC Share
n=14771
30
Practitioners
n=14771
492.4
Apps / Practitioner
n=14771

Portfolio Summary

5
Total Pending OAs
5
Non-Final OAs
0
Final Rejections
0
Advisory / Quayle

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

2
Hard (40%)
2
Medium (40%)
1
Easy (20%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only1 (20%)
§112 only1 (20%)
Double-patenting + other1 (20%)
Multi-statute (no §101)2 (40%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

5
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

50 h
Manual time on pending OAs
10 h
Time saved (low, 20%)
18 h
Time saved (mid, 35%)
0.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
POLIAKOVA-GEORGAN, EKATERINA 1 63.9% +18.1%
GOMEZ RODRIGUEZ, JULIO WASHINGTON 1 41.4% +58.4%
DACE DENITO, ALEXANDRA GERALDINE 1 54.5% +32.6%
VIVLEMORE, TRACY ANN 1 73.0% +6.4%
ZARA, JANE J 1 71.0% +16.1%

Hard Cases (2)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
18247311 COMPOUNDS FOR MODULATING CHMP7 GOMEZ RODRIGUEZ, JULIO WASHINGTON —
17508516 COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSION ZARA, JANE J —

Interview Candidates (4)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
18457941 MODULATORS OF PNPLA3 EXPRESSION POLIAKOVA-GEORGAN, EKATERINA —
18247311 COMPOUNDS FOR MODULATING CHMP7 GOMEZ RODRIGUEZ, JULIO WASHINGTON —
18245609 PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANTISENSE OLIGONUCLEOTIDE FOR ORAL ADMINISTRATION DACE DENITO, ALEXANDRA GERALDINE —
17508516 COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSION ZARA, JANE J —

Client Portfolio (2 clients)

Top Art Units

Art UnitApps
16373
16361
16001

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18457941 MODULATORS OF PNPLA3 EXPRESSION Ionis Pharmaceuticals, Inc. POLIAKOVA-GEORGAN, EKATERINA 1637 §112Other Non-Final OA — Pending Aug 29, 2023
18247311 COMPOUNDS FOR MODULATING CHMP7 Ionis Pharmaceuticals, Inc. GOMEZ RODRIGUEZ, JULIO WASHINGTON 1637 §102§103§112 Non-Final OA — Pending Mar 30, 2023
18245609 PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANTISENSE OLIGONUCLEOTIDE FOR ORAL ADMINISTRATION Ionis Pharmceuticals, Inc. DACE DENITO, ALEXANDRA GERALDINE 1636 §102§103§112DP Non-Final OA — Pending Mar 16, 2023
17635096 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF Ionis Pharmaceuticals, Inc. VIVLEMORE, TRACY ANN 1600 §103 Non-Final OA — Pending Feb 14, 2022
17508516 COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSION Ionis Pharmaceuticals, Inc. ZARA, JANE J 1637 §102§103§112 Non-Final OA — Pending Oct 22, 2021

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Frequently Asked Questions

What is Sheppard Mullin Richter & Hampton Llp-Ionis Pharm's patent allowance rate?

87.1% of resolved applications prosecuted by Sheppard Mullin Richter & Hampton Llp-Ionis Pharm were allowed, across 14,771 applications in USPTO records.

How many office actions does Sheppard Mullin Richter & Hampton Llp-Ionis Pharm average before allowance?

3.19 office actions per allowed application on average.

How many pending office actions does Sheppard Mullin Richter & Hampton Llp-Ionis Pharm have?

5 pending office actions as of October 2026, for 2 clients, before 5 examiners in 3 art units.

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