Prosecution Insights
Last updated: April 19, 2026
Application No. 16/954,678

POWDERY MILDEW RESISTANT SUNFLOWER

Final Rejection §112
Filed
Jun 17, 2020
Examiner
KUBELIK, ANNE R
Art Unit
1663
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Syngenta Crop Protection AG
OA Round
12 (Final)
76%
Grant Probability
Favorable
13-14
OA Rounds
2y 9m
To Grant
76%
With Interview

Examiner Intelligence

Grants 76% — above average
76%
Career Allow Rate
1001 granted / 1308 resolved
+16.5% vs TC avg
Minimal -1% lift
Without
With
+-1.0%
Interview Lift
resolved cases with interview
Typical timeline
2y 9m
Avg Prosecution
60 currently pending
Career history
1368
Total Applications
across all art units

Statute-Specific Performance

§101
4.8%
-35.2% vs TC avg
§103
18.8%
-21.2% vs TC avg
§102
16.3%
-23.7% vs TC avg
§112
40.9%
+0.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1308 resolved cases

Office Action

§112
DETAILED ACTION Claim 12 is pending. The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Objections Claim 12 remains objected to because --, said method-- should be inserted after “Helianthus” in line 1. Applicant did not respond to this objection in the response filed 16 December 2025. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (B) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of the second paragraph of 35 U.S.C. 112: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claim 12 is rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter that the inventor or a joint inventor, or for pre-AIA the applicant, regards as the invention. The rejection is repeated for the reasons of record as set forth in the Office action mailed 22 September 2025. Applicant’s arguments filed 16 December 2025 have been fully considered but they are not persuasive. Claim 12 is indefinite in its recitation of “comprising crossing a first parent Helianthus plant, wherein representative plant tissue of hybrid Helianthus plant ‘SUR67-1’ is deposited under NCMA No. ____”. First, the claim is indefinite because it is not clear if the deposited plant tissue has any relationship to the “first parent Helianthus plant”. If it does not, it is not clear what the first parent Helianthus plant is. Second, it is unclear what hybrid Helianthus plant ‘SUR67-1’ is and what will be deposited. Interspecific Helianthus plant SUR67-1 was produced from a cross of female parent interspecific hybrid H. annuus x H. argophyllus HELAC0001 with male parent H. debilis plant HELAB0103-2V (example 1). In the response filed 3 August 2023 to the Request for Information under 37 CFR 1.105, Applicant stated that H. annuus x H. argophyllus HELAC0001 is a heterozygous F1 hybrid, one plant of which was used as the female parent in the cross to make SUR67-1 (response to f, on pg 4) and that HELAB0103-2V is a homozygous inbred plant (response to g, on pg 5). Gametes produced from inbred parent HELAB0103-2V will each be genetically identical. When hybrid parent HELAC0001 produces gametes, crossing over occurs and each of the gametes get a different portion of each of the H. annuus and H. argophyllus parent genomes; each gamete will be different genetically. When HELAB0103-2V and HELAC0001 are crossed, each progeny will get the same set of chromosomes from inbred parent HELAB0103-2V and each will get a different set of chromosomes from hybrid parent HELAC0001. The resulting progeny are a genus of plants with a mixture of genotypes. It is not clear if “SUR67-1” refers to a single plant selection from this genus of progeny or if refers to this genus of progeny as a whole. The specification is not clear which SUR67-1 is (example 1). In the response filed 3 August 2023 to the Request for Information under 37 CFR 1.105, Applicant merely said that “SUR67-1 is a heterozygous F1 hybrid” (response to e, on pg 4); this would be true whether “SUR67-1” refers to a single plant or a genus of plants. The seed deposit referenced in the specification further muddies this. The “SEED DEPOSIT DETAILS” on pg 7 of the specification states Seed of the variety Helianthus Interspecific Hybrid SUR67-1 (4A994) made from H. annuus x H. argophyllus x H. debilis is deposited under the terms of the Budapest Treaty American Type Culture Collection (ATCC) Patent Depository, 10801 University Blvd., Manassas, VA 20110. The ATCC number of the deposit is PTA-125012. In the response filed 3 August 2023 to the Request for Information under 37 CFR 1.105, Applicant admitted that seed of SUR67-1 was not deposited; what was deposited was a “backcross generation (to HELAB0103-2V) seeds” (response to d, on pg 4), presumably because “SUR67-1 is a vegetative sterile F1 hybrid plant” (response to d, on pg 4) that is propagated vegetatively (response to e, on pg 4). Thus, “representative plant tissue of hybrid Helianthus plant ‘SUR67-1’ is deposited under NCMA No. ____” is indefinite. It is not clear what plant tissue is being deposited. Is the plant tissue from a plant of a single heterozygous genotype or is it plant tissue from a mixture of plants, each with a different of heterozygous genotype? Further, if “SUR67-1” refers to a genus of plants, each of a different genotype, it is unclear how many plants of this genus are need to be representative of “SUR67-1” and thus how many genetically different vegetative tissues must be deposited to represent SUR67-1. Response to Arguments Applicant requests that an indefiniteness rejection because the deposit number is blank be held in abeyance until the deposit can be made. (response pg 3). This is not found persuasive. The rejection was not made because the deposit number is blank. The rejection was made because it is not clear if the deposited plant tissue has any relationship to the “first parent Helianthus plant” recited in lines 1-2 of the claim. The rejection was also made because it is unclear what hybrid Helianthus plant ‘SUR67-1’ is and what will be deposited, as detailed in the rejection above. Will it be vegetative material/a cutting from a mixture of plants or vegetative material/a cutting of a single plant? Each of the vegetative cuttings from a mixture of plants of different genotypes can be uniform and stable but the deposit still be a mixture. Further, rejections cannot be held in abeyance. The following is a quotation of 35 U.S.C. 112(a): (a) IN GENERAL.—The specification shall contain a written description of the invention, and of the manner and process of making and using it, in such full, clear, concise, and exact terms as to enable any person skilled in the art to which it pertains, or with which it is most nearly connected, to make and use the same, and shall set forth the best mode contemplated by the inventor or joint inventor of carrying out the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), first paragraph: The specification shall contain a written description of the invention, and of the manner and process of making and using it, in such full, clear, concise, and exact terms as to enable any person skilled in the art to which it pertains, or with which it is most nearly connected, to make and use the same and shall set forth the best mode contemplated by the inventor of carrying out his invention. Claim 12 is rejected under 35 U.S.C. 112(a) or 35 U.S.C. 112 (pre-AIA ), first paragraph, as failing to comply with the written description requirement. The claim contains subject matter that was not described in the specification in such a way as to reasonably convey to one skilled in the relevant art that the inventor or a joint inventor, or for pre-AIA the inventor(s), at the time the application was filed, had possession of the claimed invention. The rejection is repeated for the reasons of record as set forth in the Office action mailed 22 September 2025. Applicant’s arguments filed 16 December 2025 have been fully considered but they are not persuasive. A. The claims require interspecific hybrid Helianthus SUR67-1 plant, wherein representative tissue sample will be deposited. The specification does not provide a sufficient description of SUR67-1. The specification teaches that interspecific Helianthus plant SUR67-1 was produced from a cross of female parent interspecific hybrid H. annuus x H. argophyllus HELAC0001 with male parent H. debilis plant HELAB0103-2V (example 1). In the response filed 3 August 2023 to the Request for Information under 37 CFR 1.105, Applicant stated that H. annuus x H. argophyllus HELAC0001 is a heterozygous F1 hybrid, one plant of which was used as the female parent in the cross to make SUR67-1 (response to f, on pg 4) and that HELAB0103-2V is a homozygous inbred plant (response to g, on pg 5). Gametes produced from inbred parent HELAB0103-2V will each be genetically identical. When hybrid parent HELAC0001 produces gametes, crossing over occurs and each of the gametes get a different portion of each of the H. annuus and H. argophyllus parent genomes; each gamete will be different genetically. When HELAB0103-2V and HELAC0001 are crossed, each progeny will get the same set of chromosomes from inbred parent HELAB0103-2V and each will get a different set of chromosomes from hybrid parent HELAC0001. The resulting progeny are a genus of plants with a mixture of genotypes. The specification does not state whether “SUR67-1” refers to a single plant selection from this genus of progeny or if refers to this genus of progeny as a whole. The seed deposit referenced in the specification further muddies this. The “SEED DEPOSIT DETAILS” on pg 7 of the specification states Seed of the variety Helianthus Interspecific Hybrid SUR67-1 (4A994) made from H. annuus x H. argophyllus x H. debilis is deposited under the terms of the Budapest Treaty American Type Culture Collection (ATCC) Patent Depository, 10801 University Blvd., Manassas, VA 20110. The ATCC number of the deposit is PTA-125012. In the response filed 3 August 2023 to the Request for Information under 37 CFR 1.105, Applicant admitted that seed of SUR67-1 was not deposited; what was deposited was a “backcross generation (to HELAB0103-2V) seeds” (response to d, on pg 4), presumably because “SUR67-1 is a vegetative sterile F1 hybrid plant” (response to d, on pg 4) that is propagated vegetatively (response to e, on pg 4). Thus, even if “SUR67-1” refers to a single plant selection, what was deposited was a genus of plants that are not “SUR67-1”. The structural features that distinguish SUR67-1 from other H. annuus x H. argophyllus x H. debilis plants are not described in the specification. If “SUR67-1” refers to a single plant selection, the structural features that distinguish SUR67-1 from other progeny of a cross between female parent H. annuus x H. argophyllus HELAC0001 and male parent H. debilis plant HELAB0103-2V are not described in the specification. B. The specification does not describe SUR67-1 other than to show it has a larger flower diameter than its parents, a larger width under some growing conditions than its parents, and a height that is intermediate between its parents, and that it has powdery mildew resistance (Table 1). The specification fails to describe if “SUR67-1” in Table 1 is an F1 plant of a single genotype, a mixture of F1 plants of a population of genotypes, a BC1F1 plant of a single genotype, or a mixture of BC1F1 plants of a population of genotypes. Regardless, a description of flower diameter, width, and height relative to other plants and powdery mildew resistance is not a sufficient description. A deposit is not substitute for a description of a claimed invention. The instant specification it does not provide a description sufficient to conduct an to conduct an examination, including search of the prior art MPEP 2163 (I) states “The written description of the deposited material needs to be as complete as possible because the examination for patentability proceeds solely on the basis of the written description. See, e.g., In re Lundak, 773 F.2d 1216, 227 USPQ 90 (Fed. Cir. 1985); see also 54 Fed. Reg. at 34,880 ("As a general rule, the more information that is provided about a particular deposited biological material, the better the examiner will be able to compare the identity and characteristics of the deposited biological material with the prior art.").” The instant specification also fails to satisfy the written description because it does not provide enough description to be sufficient to aid in the resolution of questions of infringement. MPEP 2163(I) states “The description must be sufficient to permit verification that the deposited biological material is in fact that disclosed. Once the patent issues, the description must be sufficient to aid in the resolution of questions of infringement." Id. at 34,880.)” (Quoting the Deposit of Biological Materials for Patent Purposes, Final Rule, 54 Fed. Reg. 34,864 (August 22, 1989) at 34,880). Hence, Applicant has not, in fact, described SUR67-1, and the specification fails to provide an adequate written description of the claimed invention. Because SUR67-1 is not described, the method of the using plant is likewise not described, and the specification fails to provide an adequate written description of the claimed invention. Therefore, given the lack of written description in the specification with regard to the structural and functional characteristics of the claimed compositions, Applicant does not appear to have been in possession of the claimed genus at the time this application was filed. Response to Arguments Applicant urges that a deposit will be made to satisfy the written description requirement (response pg 3). This is not found persuasive. A deposit where Applicant will not reveal what is in the deposit (vegetative material from a mixture of plants or vegetative material of a single plant, and if the latter what the characteristics of that plant are) does not meet the written description requirements. Written description also requires a description of the deposit. Whether SUR67-1 is a genus of plants, each of a different genotype, or if it is a plant of a single heterozygous genotype, Applicant should provide support for that in the originally filed specification. If there is no support for one or the other, then a deposit limiting SUR67-1 to a genus of plants, each of a different genotype, or to a plant of a single heterozygous genotype would be new matter. Applicant urges that the response to the 105 request provided additional information for examination (response pg 3). This is not found persuasive. As detailed in the rejection above, the response to the 105 request made it less clear as to what the deposit will be than before. Claim 12 is rejected under 35 U.S.C. 112(a) or 35 U.S.C. 112 (pre-AIA ), first paragraph, as failing to comply with the enablement requirement. The claim(s) contains subject matter which was not described in the specification in such a way as to enable one skilled in the art to which it pertains, or with which it is most nearly connected, to make and/or use the invention. The rejection is repeated for the reasons of record as set forth in the Office action mailed 22 September 2025. Applicant’s arguments filed 16 December 2025 have been fully considered but they are not persuasive. The claim requires a deposit of plant tissue of hybrid Helianthus variety SUR67-1. It is noted that Applicant intends to deposit tissue of SUR67-1 at the NCMA, but there is no indication that the tissue has been deposited. Further, there is no affirmative statement in the specification that all restrictions upon availability to the public will be irrevocably removed upon granting of the patent. It is not clear what plant tissue is being deposited. It is not clear if the plant tissue from a plant of a single heterozygous genotype or if it is it plant tissue from a mixture of plants, each with a different of heterozygous genotype. If the deposit of this tissue is made under the terms of the Budapest Treaty, then an affidavit or declaration by the Applicant, or a statement by an attorney of record over his or her signature and registration number, stating that the tissue will be irrevocably and without restriction or condition released to the public upon the issuance of a patent would satisfy the deposit requirement made herein. If the deposit is not been made under the Budapest Treaty, then in order to certify that the deposit, meets the requirements set forth in 37 CFR 1.801-1.809, Applicant may provide assurance of compliance by an affidavit or declaration, or by a statement by an attorney of record over his or her signature and registration number showing that (a) during the pendency of the application, access to the invention will be afforded to the Commissioner upon request; (b) all restrictions upon availability to the public will be irrevocably removed upon granting of the patent; (c) the deposit will be maintained in a public depository for a period of 30 years or 5 years after the last request or for the enforceable life of the patent, whichever is longer; and (d) the viability of the biological material at the time of deposit will be tested (see 37 CFR 1.807). In addition, the identifying information set forth in 37 CFR 1.809(d) should be added to the specification. See 37 CFR 1.801 - 1.809 [MPEP 2401-2411.05] for additional explanation of these requirements. Response to Arguments Applicant urges that a deposit will be made to satisfy the enablement requirement and makes a deposit statement(response pg 3). This is not found persuasive because it is not clear what will be deposited, a plant tissue from a plant of a single heterozygous genotype or plant tissue from a mixture of plants, each with a different of heterozygous genotype? Since that is unknown, it cannot be determined if the deposit will satisfy the Enablement requirement. This is not found persuasive because it is not clear what will be deposited, a plant tissue from a plant of a single heterozygous genotype or plant tissue from a mixture of plants, each with a different of heterozygous genotype? Since that is unknown, it cannot be determined if the deposit will satisfy the Enablement requirement. Conclusion No claim is allowed. THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any extension fee pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Anne R. Kubelik, Ph.D., whose telephone number is (571) 272-0801. The examiner can normally be reached Monday through Friday, 9:00 am - 5:00 pm Eastern. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Amjad Abraham, can be reached at (571) 270-7058. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /Anne Kubelik/Primary Examiner, Art Unit 1663
Read full office action

Prosecution Timeline

Jun 17, 2020
Application Filed
May 14, 2021
Non-Final Rejection — §112
Aug 26, 2021
Response after Non-Final Action
Aug 26, 2021
Response Filed
Dec 08, 2021
Response Filed
Jan 18, 2022
Final Rejection — §112
Apr 18, 2022
Request for Continued Examination
Apr 19, 2022
Response after Non-Final Action
Apr 27, 2022
Non-Final Rejection — §112
Aug 02, 2022
Response Filed
Aug 25, 2022
Final Rejection — §112
Oct 31, 2022
Response after Non-Final Action
Nov 30, 2022
Request for Continued Examination
Dec 05, 2022
Response after Non-Final Action
Feb 27, 2023
Non-Final Rejection — §112
Aug 03, 2023
Response Filed
Sep 01, 2023
Non-Final Rejection — §112
Dec 07, 2023
Response Filed
Dec 07, 2023
Response after Non-Final Action
Mar 08, 2024
Response Filed
Mar 13, 2024
Final Rejection — §112
Jun 18, 2024
Request for Continued Examination
Jun 23, 2024
Response after Non-Final Action
Jul 29, 2024
Final Rejection — §112
Dec 02, 2024
Request for Continued Examination
Dec 03, 2024
Response after Non-Final Action
Dec 16, 2024
Non-Final Rejection — §112
Mar 20, 2025
Response Filed
Apr 08, 2025
Final Rejection — §112
Aug 14, 2025
Request for Continued Examination
Aug 15, 2025
Response after Non-Final Action
Sep 18, 2025
Non-Final Rejection — §112
Dec 16, 2025
Response Filed
Jan 14, 2026
Final Rejection — §112 (current)

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Prosecution Projections

13-14
Expected OA Rounds
76%
Grant Probability
76%
With Interview (-1.0%)
2y 9m
Median Time to Grant
High
PTA Risk
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