Last updated: April 19, 2026

Application No. 17/441,149

INHIBITION OF NAMPT AND/OR SARM1 FOR THE TREATMENT OF AXONAL DEGRADATION

Final Rejection

Filed

Sep 20, 2021

Examiner

YOO, SUN JAE

Art Unit

1621

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

The Johns Hopkins University

OA Round

2 (Final)

Interview Optional

— +0.4% interview lift. This examiner has a relatively high allow rate; a written response may suffice.

Based on 1225 resolved cases, 2023–2026

Examiner Intelligence

YOO, SUN JAE View full profile →

Grants 71% — above average

Career Allow Rate

869 granted / 1225 resolved

+10.9% vs TC avg

Minimal +0% lift

Without

With

+0.4%

Interview Lift

resolved cases with interview

Typical timeline

2y 11m

Avg Prosecution

43 currently pending

Career history

1268

Total Applications

across all art units

Statute-Specific Performance

§101

0.5%

-39.5% vs TC avg

§103

14.6%

-25.4% vs TC avg

§102

29.8%

-10.2% vs TC avg

§112

32.5%

-7.5% vs TC avg

Black line = Tech Center average estimate • Based on career data from 1225 resolved cases

Prosecution Timeline

Sep 20, 2021

Application Filed

Jun 18, 2025

Response Filed

Sep 11, 2025

Non-Final Rejection

Dec 16, 2025

Response Filed

Feb 10, 2026

Final Rejection (current)

Precedent Cases

Applications granted by this same examiner with similar technology

17/251,658

Patent 12595251

AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS

2y 5m to grant Granted Apr 07, 2026

17/432,926

Patent 12594266

TRITERPENOID ANTIFUNGALS FOR THE TREATMENT OR PREVENTION OF PNEUMOCYSTIS SPP. PNEUMONIA

2y 5m to grant Granted Apr 07, 2026

17/482,230

Patent 12583854

KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

2y 5m to grant Granted Mar 24, 2026

17/626,318

Patent 12583855

RET SELECTIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF

2y 5m to grant Granted Mar 24, 2026

18/421,849

Patent 12583821

SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT

2y 5m to grant Granted Mar 24, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

AI Strategy Recommendation

Get an AI-powered prosecution strategy using examiner precedents, rejection analysis, and claim mapping.

Prosecution Projections

3-4

Expected OA Rounds

71%

Grant Probability

71%

With Interview (+0.4%)

2y 11m

Median Time to Grant

Moderate

PTA Risk

Based on 1225 resolved cases by this examiner. Grant probability derived from career allow rate.

INHIBITION OF NAMPT AND/OR SARM1 FOR THE TREATMENT OF AXONAL DEGRADATION

Interview Optional

Examiner Intelligence

Statute-Specific Performance

Prosecution Timeline

Precedent Cases

Applications granted by this same examiner with similar technology

AI Strategy Recommendation

Prosecution Projections

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