Last updated: May 04, 2026

Application No. 17/441,149

INHIBITION OF NAMPT AND/OR SARM1 FOR THE TREATMENT OF AXONAL DEGRADATION

Final Rejection

Filed

Sep 20, 2021

Priority

Mar 20, 2019 — provisional 62/821,214 +2 more

Examiner

YOO, SUN JAE

Art Unit

1621

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

The Johns Hopkins University

OA Round

2 (Final)

Interview Optional

— +0.0% interview lift. Interview lift (+0.0%) is below the 15.0% threshold. A written response is recommended.

Based on 1226 resolved cases, 2023–2026

Examiner Intelligence

YOO, SUN JAE View full profile →

Grants 71% — above average

Career Allowance Rate

870 granted / 1226 resolved

+11.0% vs TC avg

Minimal +0% lift

Without

With

+0.0%

Interview Lift

resolved cases with interview

Typical timeline

2y 8m

Avg Prosecution

45 currently pending

Career history

1271

Total Applications

across all art units

Statute-Specific Performance

§101

0.5%

-39.5% vs TC avg

§103

14.7%

-25.3% vs TC avg

§102

29.8%

-10.2% vs TC avg

§112

32.4%

-7.6% vs TC avg

Black line = Tech Center average estimate • Based on career data from 1226 resolved cases

Prosecution Timeline

Sep 20, 2021

Application Filed

Jun 18, 2025

Response Filed

Sep 11, 2025

Non-Final Rejection

Dec 16, 2025

Response Filed

Feb 10, 2026

Final Rejection (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/006,068

Patent 12612377

PROCESS FOR PREPARING AMINOFURANES

3y 3m to grant Granted Apr 28, 2026

18/509,586

Patent 12611412

TARGETING THE TLK1/NEK1 AXIS IN PROSTATE CANCER

2y 5m to grant Granted Apr 28, 2026

18/004,837

Patent 12604896

MIXTURE OF LEVONOGESTREL AND ETHINYLESTRADIOL AS CONTROL FOR BARK INSECTS

3y 3m to grant Granted Apr 21, 2026

17/251,658

Patent 12595251

AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS

5y 3m to grant Granted Apr 07, 2026

17/432,926

Patent 12594266

TRITERPENOID ANTIFUNGALS FOR THE TREATMENT OR PREVENTION OF PNEUMOCYSTIS SPP. PNEUMONIA

4y 7m to grant Granted Apr 07, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

3-4

Expected OA Rounds

71%

Grant Probability

71%

With Interview (+0.0%)

2y 8m (~0m remaining)

Median Time to Grant

Moderate

PTA Risk

Based on 1226 resolved cases by this examiner. Grant probability derived from career allowance rate.