Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
186 pending office actions • 89 art units • 164 examiners • 0 of 186 (0%) have an AI response strategy ready • 119 patents granted in the last 365 days
The Johns Hopkins University manages a portfolio with 186 pending office actions in the Biotechnology & Pharmaceuticals technology area. These actions are distributed across 79 distinct art units, showcasing the university's research and development reach. The prosecution involves 168 distinct examiners, which means that the count of pending cases is higher than the count of examiners assigned to them.
SCHLOOP, ALLISON ELIZABETH is the busiest examiner for the portfolio, currently overseeing 3 pending office actions. Despite the total of 186 pending office actions, the workload is distributed, as evidenced by the 168 distinct examiners assigned. This count of 79 distinct art units requires a prosecution strategy to address the specific technical nuances of many different specialized groups within the Biotechnology & Pharmaceuticals sector. The distribution of cases ensures that the university's patenting outcomes are spread across many individuals, with the busiest examiner handling only 3 of the pending matters.
Based on the USPTO statutory response window for each pending office action. 68 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 68 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 4 (2%) |
| §101 + other | 22 (12%) |
| §103 only | 44 (24%) |
| §102 only | 6 (3%) |
| §112 only | 11 (6%) |
| Double-patenting only | 4 (2%) |
| Double-patenting + other | 21 (11%) |
| Multi-statute (no §101) | 74 (40%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| ZEC, FILIP | 3 | 65.7% | +13.8% |
| SCHLOOP, ALLISON ELIZABETH | 3 | 63.0% | +56.5% |
| PERREIRA, MELISSA JEAN | 2 | 52.0% | +25.8% |
| SAMALA, JAGADISHWAR RAO | 2 | 67.9% | +55.7% |
| CHERNYSHEV, OLGA N | 2 | 54.5% | +34.4% |
| LEWOCZKO, EVAN MICHAEL | 2 | — | — |
| HEASLEY, MEGHAN CHRISTINE | 2 | 75.2% | +34.0% |
| KIM, DANIELLE A | 2 | 37.1% | +56.3% |
| HOWELL, THEODORE R | 2 | 66.7% | +25.4% |
| GRAY, JESSICA | 2 | 0.0% | +0.0% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 16763827 | COMPOSITIONS AND METHODS FOR EFFICIENT GENOME EDITING | WHITEMAN, BRIAN A | 146d overdue |
| 18030465 | DETECTION OF ACE2 IgM AUTOANTIBODIES AS MARKERS OF SEVERITY AND MECHANISM IN COVID19 PATIENTS | GILL, RACHEL B | 124d overdue |
| 18850458 | Leg Support for Orthopaedic Surgery | RODRIQUEZ, KARI KRISTIN | 104d overdue |
| 18255767 | COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN | MARTIN, KEVIN STEPHEN | 78d overdue |
| 18261366 | METHODS OF DETECTING HIGH RISK BARRETT'S ESOPHAGUS WITH DYSPLASIA, AND ESOPHAGEAL ADENOCARCINOMA | DAUNER, JOSEPH G | 77d overdue |
| 18698097 | AUTOMATIC RADIOTHERAPY PRESCRIPTION ANOMALY DETECTION | COBANOGLU, DILEK B | 56d overdue |
| 17550542 | BIOMIMETIC ANISOTROPIC POLYMERIC PARTICLES WITH NATURALLY DERIVED CELL MEMBRANES FOR ENHANCED DRUG DELIVERY | DONOHUE, SEAN R | 53d overdue |
| 18441540 | System And Method For Displaying An Image | SHAFQAT, AMY JEANETTE | 52d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18990863 | IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING FIBROBLAST-ACTIVATION PROTEIN-ALPHA (FAP-ALPHA) | PERREIRA, MELISSA JEAN | 78d overdue |
| 18107336 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | HOWELL, THEODORE R | 78d overdue |
| 18376127 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | HOWELL, THEODORE R | 50d overdue |
| 17771772 | COMPOSITIONS AND METHODS FOR DETECTING AND TREATING ESOPHAGEAL CANCER | SCHLOOP, ALLISON ELIZABETH | 46d overdue |
| 18380984 | NanoMesh Drug Delivery for Treatment of Brain Tumors | KIM, DANIELLE A | 25d overdue |
| 18657340 | CITRULLINATED BRAIN AND NEUROLOGICAL PROTEINS AS BIOMARKERS OF BRAIN INJURY OR NEURODEGENERATION | CHERNYSHEV, OLGA N | 8d overdue |
| 18550371 | DELIVERY OF MACROMOLECULES USING MICROINJECTORS | KIM, DANIELLE A | 34d |
| 18548423 | ANTI-FIBROTIC THERAPIES | HEASLEY, MEGHAN CHRISTINE | 42d |
| Art Unit | Apps |
|---|---|
| 1618 | 11 |
| 1682 | 8 |
| 3798 | 6 |
| 1675 | 6 |
| 1683 | 6 |
| 3791 | 5 |
| 1685 | 5 |
| 3763 | 4 |
| 2877 | 4 |
| 1619 | 4 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19482406 | OPERATOR-INDEPENDENT ULTRASOUND IMAGING | FRITH, SEAN A | 3798 | §102§103 | Non-Final OA | — | Pending | Nov 07, 2025 |
| 19286066 | REAL-TIME ULTRASOUND MONITORING FOR ABLATION THERAPY | BYKHOVSKI, ALEXEI | 3798 | §102§103 | Non-Final OA | — | Pending | Jul 30, 2025 |
| 19238047 | ROBOTIC TASK COMPLETION FROM NATURAL LANGUAGE REQUESTS | HANNAN, B M M | 3657 | §101§112 | Non-Final OA | — | Pending | Jun 13, 2025 |
| 19136781 | Vehicle Recovery System | CURRY, CINDI M | 3642 | §102§103§112 | Non-Final OA | — | Pending | Jun 06, 2025 |
| 19174285 | NEUROMODULATION BASED NERVE IDENTIFICATION | MATTSON, SEAN D | 3798 | §103§112Other | Non-Final OA | 36d | Pending | Apr 09, 2025 |
| 19112143 | MACHINE LEARNING SYSTEMS AND RELATED ASPECTS FOR THE DETECTION OF DISEASE STATES | ELSHAER, ALAAELDIN M | 3687 | §101§102§103 | Final Rejection | — | Pending | Mar 14, 2025 |
| 18997669 | LATTICE HEATSINK FOR IMPINGEMENT COOLING | RUBY, TRAVIS C | 3763 | §102 | Non-Final OA | — | Pending | Jan 22, 2025 |
| 18990863 | IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING FIBROBLAST-ACTIVATION PROTEIN-ALPHA (FAP-ALPHA) | PERREIRA, MELISSA JEAN | 1618 | §103DP | Final Rejection | 78d overdue | Pending | Dec 20, 2024 |
| 18877461 | METHODS AND RELATED ASPECTS FOR CHARACTERIZING LABELED NANOPARTICLES | RIZVI, AKBAR HASSAN | 2877 | §103 | Non-Final OA | — | Pending | Dec 20, 2024 |
| 18977262 | CONTROLLED OUTGASSING OF HYPERBARICALLY LOADED MATERIALS FOR THE DELIVERY OF OXYGEN AND OTHER THERAPEUTIC GASES IN BIOMEDICAL APPLICATIONS | SINGH, SATYENDRA K | 1657 | §103 | Non-Final OA | — | Pending | Dec 11, 2024 |
| 18972277 | IN SITU NUCLEIC ACID ANALYSIS USING PROBE PAIR LIGATION | KENNEDY, SARAH JANE | 1682 | §112 | Final Rejection | — | Pending | Dec 06, 2024 |
| 18871568 | DETECTING BINOCULAR EYE ALIGNMENT USING SIGNAL CORRELATION | BOURQUINE, MACKENZI TATE | 2872 | §102§103 | Non-Final OA | — | Pending | Dec 04, 2024 |
| 18869346 | NON-ACID INHIBITORS OF INOSITOL HEXAKISPHOSPHATE KINASE (IP6K) AND METHODS OF USE THEREOF | MOORE, SUSANNA | 1624 | §102§112DP | Non-Final OA | — | Pending | Nov 26, 2024 |
| 18947884 | SYSTEMS AND METHODS FOR COLLECTING ORBITAL DEBRIS | GAITONDE, MEGHA MEHTA | 1781 | §102§103 | Non-Final OA | — | Pending | Nov 14, 2024 |
| 18935852 | PROVIDING SENSORY STIMULATIONS VIA PHOTOACOUSTIC, PIEZO-BASED, THERMAL, AND/OR ELECTRICAL EFFECTS | JOHNSON, NICOLE F | 3796 | §103Other | Non-Final OA | — | Pending | Nov 04, 2024 |
| 18861291 | PENEM ANTIBACTERIALS AGAINST MYCOBACTERIAL PATHOGENS AND D,D- AND L,D TRANSPEPTIDASES | BRAUN, MADELINE E | 1624 | §102§103§112DP | Non-Final OA | — | Pending | Oct 29, 2024 |
| 18857693 | Device for Early Detection of Pediatric IV Infiltration | SCHMIDT, EMILY LOUISE | 3783 | §102§103 | Non-Final OA | — | Pending | Oct 17, 2024 |
| 18855981 | METHOD OF MEASURING LEVEL OF IMMUNE SUPPRESSION | DRISCOLL, LORA E BARNHART | 3991 | §101§102§103 | Non-Final OA | — | Pending | Oct 10, 2024 |
| 18854168 | METHODS AND MATERIALS FOR TREATING SYNGAP1-ASSOCIATED NEURODEVELOPMENTAL DISORDERS | CANDELARIA, JULIANA IRENE | 1634 | §102§103§112 | Non-Final OA | — | Pending | Oct 04, 2024 |
| 18850458 | Leg Support for Orthopaedic Surgery | RODRIQUEZ, KARI KRISTIN | 3786 | §102§112 | Final Rejection | 104d overdue | Pending | Sep 24, 2024 |
| 18847731 | ADDITIVE MANUFACTURING OF ULTRA-HIGH-TEMPERATURE CERAMICS | YANG, JIE | 1734 | §102§103§112DP | Non-Final OA | — | Pending | Sep 17, 2024 |
| 18883232 | RAPID ANEUPLOIDY DETECTION | CHUNDURU, SURYAPRABHA | 1681 | §103DP | Final Rejection | — | Pending | Sep 12, 2024 |
| 18844364 | METHOD AND SYSTEM FOR DELIVERY OF THERAPEUTICS TO EYE | MENSH, ANDREW J | 3781 | §102§103§112 | Non-Final OA | — | Pending | Sep 05, 2024 |
| 18818731 | BIOMARKERS USEFUL IN THE TREATMENT OF SUBJECTS HAVING DISEASES OF THE EYE | RAO, SAVITHA M | 1691 | §102§103DP | Non-Final OA | — | Pending | Aug 29, 2024 |
| 18839307 | FLUID ANALYSIS SYSTEM AND METHODS | AKANBI, ISIAKA O | 2877 | §102 | Final Rejection | — | Pending | Aug 16, 2024 |
| 18839298 | REGISTRATION OF DEFORMABLE STRUCTURES | SOFRONIOU, MICHAEL MARIO | 2661 | §103§112 | Non-Final OA | — | Pending | Aug 16, 2024 |
| 18834007 | ORBITAL RESILIENT BLOCKCHAIN-ENABLED INTER-AGENT TRANSACTION SERVICE PROTOCOL | NARRAMORE, BLAKE I | 2438 | §103 | Final Rejection | — | Pending | Jul 29, 2024 |
| 18773723 | SUBMERSIBLE VEHICLE WITH A FLOODABLE ACTUATOR VESSEL | FIGUEROA, MICHAEL KENN POTICANO | 3615 | §103 | Non-Final OA | — | Pending | Jul 16, 2024 |
| 18772628 | PSMA-BINDING AGENTS AND USES THEREOF | SAMALA, JAGADISHWAR RAO | 1618 | DP | Non-Final OA | — | Pending | Jul 15, 2024 |
| 18768619 | HIGH THROUGHPUT ELECTROCHEMICAL EXPERIMENTATION DEVICES AND METHODS | GAMBLE JR, RANDALL LEE | 1795 | §103 | Final Rejection | 55d | Pending | Jul 10, 2024 |
| 18754996 | SYNTHESIS OF THE RADIOLABELED PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR [18F]DCFPYL | SAMALA, JAGADISHWAR RAO | 1618 | §101§102§103DP | Non-Final OA | — | Pending | Jun 26, 2024 |
| 18721824 | COMPOUNDS FOR TREATMENT OF CANCER | NOTTINGHAM, KYLE GREGORY | 1621 | §102§103 | Non-Final OA | — | Pending | Jun 19, 2024 |
| 18715998 | METHODS AND RELATED ASPECTS FOR MITIGATING UNKNOWN BIASES IN COMPUTED TOMOGRAPHY DATA | BEKELE, MEKONEN T | 2699 | §102§103 | Non-Final OA | — | Pending | Jun 03, 2024 |
| 18657340 | CITRULLINATED BRAIN AND NEUROLOGICAL PROTEINS AS BIOMARKERS OF BRAIN INJURY OR NEURODEGENERATION | CHERNYSHEV, OLGA N | 1675 | §112DP | Non-Final OA | 8d overdue | Pending | May 07, 2024 |
| 18652334 | INTEGRATED ELECTROCHEMICAL APTASENSORS FOR MEASURING CELL DEATH AND CYTOKINE ACTIVITY FROM INTACT TISSUE SAMPLES | QIAN, SHIZHI | 1795 | §102§103§112 | Final Rejection | 70d | Pending | May 01, 2024 |
| 18705720 | CONTROLLING HOMEOSTATIC REGULATORY CIRCUITRY IN HYPOTHALAMUS | GU, QINHUA | 1633 | §102§112 | Non-Final OA | — | Pending | Apr 29, 2024 |
| 18703915 | USE OF BIOMARKERS IN DIAGNOSING AND TREATING LUPUS NEPHRITIS | SODERQUIST, ARLEN | 1797 | §101§102§103§112 | Non-Final OA | — | Pending | Apr 23, 2024 |
| 18630226 | SURFACE-FORMED FIDUCIAL MARKERS AND SURGICAL OBJECT TRACKING | SILVA-AVINA, EMMANUEL | 2673 | §102§103 | Non-Final OA | — | Pending | Apr 09, 2024 |
| 18698097 | AUTOMATIC RADIOTHERAPY PRESCRIPTION ANOMALY DETECTION | COBANOGLU, DILEK B | 3687 | §101 | Non-Final OA | 56d overdue | Pending | Apr 03, 2024 |
| 18693636 | MRNA REGULON THERAPY FOR THE TREATMENT OF HAPLOINSUFFICIENCY DISORDERS | GROOMS, TIFFANY NICOLE | 1637 | §101§102§103§112 | Non-Final OA | — | Pending | Mar 20, 2024 |
| 18689342 | APTAMER-BASED ELECTROCHEMICAL VIRUS DETECTOR AND METHODS THEREOF | KWAK, DEAN P | 1798 | §102§112Other | Non-Final OA | — | Pending | Mar 05, 2024 |
| 18591714 | SYSTEMS AND METHODS OF THERMOCHEMICALLY REDUCING METALLIC ELEMENTS USING THERMAL SHOCK | WANG, NICHOLAS A | 1734 | §102§103 | Non-Final OA | — | Pending | Feb 29, 2024 |
| 18688195 | CONTROLLED LONG-TERM DRUG DELIVERY AND METHODS THEREOF | OTTON, ALICIA L | 1699 | §102 | Final Rejection | — | Pending | Feb 29, 2024 |
| 18581931 | AUTOIMMUNE ANTIBODIES FOR USE IN INHIBITING CANCER CELL GROWTH | WEIDNER, ADAM M | 1675 | §112 | Non-Final OA | — | Pending | Feb 20, 2024 |
| 18684083 | POLYMERS AND NANOPARTICLES FOR INTRAMUSCULAR NUCLEIC ACID DELIVERY | STEINKE, SEAN JAMES | 1619 | §102§103§112Other | Non-Final OA | — | Pending | Feb 15, 2024 |
| 18441540 | System And Method For Displaying An Image | SHAFQAT, AMY JEANETTE | 3798 | §103§112 | Non-Final OA | 52d overdue | Pending | Feb 14, 2024 |
| 18294646 | AGENTS, COMPOSITIONS, AND METHODS FOR CANCER DETECTION | LEWOCZKO, EVAN MICHAEL | 1612 | §103 | Non-Final OA | — | Pending | Feb 02, 2024 |
| 18293683 | INHIBITORS OF HYPOXIA-INDUCIBLE FACTORS | CHAO, ALLEN | 1622 | §102§112 | Non-Final OA | — | Pending | Jan 30, 2024 |
| 18423361 | SUPERLATTICE STRUCTURES FOR THERMOELECTRIC DEVICES | ZEC, FILIP | 3763 | §103 | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18423360 | SUPERLATTICE STRUCTURES FOR THERMOELECTRIC DEVICES | ZEC, FILIP | 3763 | §103 | Non-Final OA | — | Pending | Jan 26, 2024 |
IP Author helps IP teams respond to office actions faster with AI-generated responses, examiner analytics, and prosecution intelligence.
Start Free TrialThe Johns Hopkins University has 186 pending office actions as of October 2026, spread across 89 art units and 164 examiners.
Filip Zec has the most, with 3 of The Johns Hopkins University's pending office actions.
Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.