Prosecution Insights
Last updated: August 15, 2026
Application No. 17/599,098

METHOD FOR PRODUCING LACTIC ACID BACTERIUM FERMENTATION FOOD PRODUCT

Non-Final OA §103
Filed
Sep 28, 2021
Priority
Mar 29, 2019 — JP 2019-065914 +1 more
Examiner
TURNER, FELICIA C
Art Unit
1793
Tech Center
1700 — Chemical & Materials Engineering
Assignee
Kabushiki Kaisha Yakult Honsha
OA Round
5 (Non-Final)
26%
Grant Probability
At Risk
5-6
OA Rounds
0m
Est. Remaining
56%
With Interview

Examiner Intelligence

Grants only 26% of cases
26%
Career Allowance Rate
167 granted / 636 resolved
-38.7% vs TC avg
Strong +30% interview lift
Without
With
+30.1%
Interview Lift
resolved cases with interview
Typical timeline
4y 2m
Avg Prosecution
40 currently pending
Career history
697
Total Applications
across all art units

Statute-Specific Performance

§101
1.0%
-39.0% vs TC avg
§103
61.5%
+21.5% vs TC avg
§102
8.8%
-31.2% vs TC avg
§112
24.6%
-15.4% vs TC avg
Black line = Tech Center average estimate • Based on career data from 636 resolved cases

Office Action

§103
DETAILED ACTION The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Receipt is acknowledged of the Request for Continued Examination (RCE) under 1.114, the Amendment and Response, all filed 5/28/26. Claims 1, 6-18 are pending. Claims 1, 6-9, 14, 15, and 16 have been examined on the merits. Claims 10-13, 17, and 18 were previously withdrawn. Continued Examination Under 37 CFR 1.114 A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous Office action has been withdrawn pursuant to 37 CFR 1.114. Applicant's submission filed on 5/28/26 has been entered. Withdrawn Rejections The 103(a) rejections of claims 1, 6-9, and 14-16 over Mizusawa et al. (US 2005/0208195) in view of Ogasawara et al. (US 9,708,579) and Sande et al. “Production of omega 3, 6, and 9 fatty acids of hydrolysis of vegetable oils…” Food Sci. Biotechnol 2018 vol. 27 (2) pg. 537-545 have been withdrawn due to the amendments to the claims. Claim Rejections - 35 USC § 103 The text of those sections of Title 35, U.S. Code not included in this action can be found in a prior Office action. Claims 1, 6-9, and 14-16 are rejected under 35 U.S.C. 103 as being unpatentable over Mizusawa et al. (US 2005/0208195) in view of Ogasawara et al. (US 9,708,579) and Sande et al. “Production of omega 3, 6, and 9 fatty acids of hydrolysis of vegetable oils…” Food Sci. Biotechnol 2018 vol. 27 (2) pg. 537-545 and Suganuma et al. US 20110318453. Regarding Claims 1, 6, and 7: Mizusawa discloses a method of making food or drink and specifically discloses fermenting a medium containing a fatty acid and a live number of bacteria from Lactobacillus casei, L. gasseri. L. johnsonii, L. bulgaricus, L. acidophilus [abstract; 0062; 0065]. Mizusawa discloses that degradation products which are the product of lipase treatment of sunflower oil can be used as the raw material that is fermented with the lactic acid bacteria [0028]. Mizusawa discloses that the unsaturated fatty acids are added before fermentation [0028; 0062]. Mizusawa discloses a fermented dairy food/fermenting milk [0062; 0065]. Mizusawa discloses animal milk as a medium [0029; 0031- 0033]. However, claim 1 is a recitation of the intended use of the claimed invention and in order to patentably distinguish the claimed invention from the prior art, the recitation must result in a structural difference between the claimed invention and the prior art. MPEP 2103 states that intended use language "does not limit a claim to a particular structure does not limit the scope of a claim". The above mentioned phrase does not limit the claim to any particular structure, so it is not interpreted to limit the scope of the claims. If the prior art structure is capable of performing the intended use, then it meets the claim. Mizusawa does not disclose wherein the amount of the lipase degradation product added is 3 to 100 ppm in terms of free fatty acids. Mizusawa does not disclose that the lipase is derived from wherein the lipase degradation product is a degradation product of a lipase at least one of the genus Candida, the genus, Rhizopus, the genus Penicillium, and the genus Aspergillus. Ogasawara discloses a method of making a fermented food product with lactic acid bacteria, L. casei, and including oleic acid (free fatty acid) or its derivatives [col. 6, lines 14-67; claims 8 and 10]. Ogasawara discloses that oleic acid and its derivatives have growth promoting and viability promoting abilities for lactic acid bacteria [abstract; col. 6, lines 14-67; claims 1, 8, and 13]. Ogasawara discloses adding oleic acid at 5 to 50 ppm [col. 6, lines 41-50]. Sande discloses free fatty acids derived from the lipase treatment of oils including olive oil, and sunflower oil [abstract]. Sande discloses the generation of free fatty acids including oleic acid [abstract]. Suganuma discloses treating vegetable oils with lipase [abstract; 0037]. Suganuma discloses sunflower oil [0037]. Suganuma discloses that the lipase can be derived from Rhizopus or Aspergillus [0037]. At the effective filing date of the invention it would have been obvious to one of ordinary skill in the art to modify the method of Mizusawa to include the free fatty acid at 5 to 50 ppm as in Ogasawara in order to aid in the growth and the viability of lactic acid bacteria. It would have been obvious that the sunflower oil of Mizusawa would have produced a lipase degradation product which was a free fatty acid including oleic acid, since Sande discloses oleic acid as a lipase hydrolysis product of sunflower and olive oils. Further it would have been obvious to utilize lipase derived from Rhizopus or Aspergillus as in Suganuma since they are able to degrade plant oils to produce fatty acids. Regarding Claim 8: Mizusawa discloses a method of making food or drink and specifically discloses fermenting a medium containing a fatty acid and a live number of bacteria from Lactobacillus casei, L. gasseri. L. johnsonii, L. bulgaricus, L. acidophilus [abstract; 0062; 0065]. Mizusawa discloses that degradation products which are the product of lipase treatment of sunflower oil can be used as the raw material that is fermented with the lactic acid bacteria [0028]. Mizusawa discloses that the unsaturated fatty acids are added before fermentation [0028; 0062]. Mizusawa discloses a fermented dairy food/fermenting milk [0062; 0065]. Mizusawa discloses animal milk as a medium [0029; 0031- 0033]. However, claim 8 is a recitation of the intended use of the claimed invention and in order to patentably distinguish the claimed invention from the prior art, the recitation must result in a structural difference between the claimed invention and the prior art. MPEP 2103 states that intended use language "does not limit a claim to a particular structure does not limit the scope of a claim". The above mentioned phrase does not limit the claim to any particular structure, so it is not interpreted to limit the scope of the claims. If the prior art structure is capable of performing the intended use, then it meets the claim. Mizusawa does not disclose wherein the amount of the lipase degradation product added is 3 to 100 ppm in terms of free fatty acids. Mizusawa does not disclose that the lipase is derived from wherein the lipase degradation product is a degradation product of a lipase at least one of the genus Candida, the genus, Rhizopus, the genus Penicillium, and the genus Aspergillus. Ogasawara discloses a method of making a fermented food product with lactic acid bacteria, L. casei, and including oleic acid (free fatty acid) or its derivatives [col. 6, lines 14-67; claims 8 and 10]. Ogasawara discloses that oleic acid and its derivatives have growth promoting and viability promoting abilities for lactic acid bacteria [abstract; col. 6, lines 14-67; claims 1, 8, and 13]. Ogasawara discloses adding oleic acid at 5 to 50 ppm [col. 6, lines 41-50]. Sande discloses free fatty acids derived from the lipase treatment of oils including olive oil, and sunflower oil [abstract]. Sande discloses the generation of free fatty acids including oleic acid [abstract]. Suganuma discloses treating vegetable oils with lipase [abstract; 0037]. Suganuma discloses sunflower oil [0037]. Suganuma discloses that the lipase can be derived from Rhizopus or Aspergillus [0037]. At the effective filing date of the invention it would have been obvious to one of ordinary skill in the art to modify the method of Mizusawa to include the free fatty acid at 5 to 50 ppm as in Ogasawara in order to aid in the growth and the viability of lactic acid bacteria. It would have been obvious that the sunflower oil of Mizusawa would have produced a lipase degradation product which was a free fatty acid including oleic acid, since Sande discloses oleic acid as a lipase hydrolysis product of sunflower and olive oils. Further it would have been obvious to utilize lipase derived from Rhizopus or Aspergillus as in Suganuma since they are able to degrade plant oils to produce fatty acids. Regarding Claim 9: Mizusawa discloses a method of making food or drink and specifically discloses fermenting a medium containing a fatty acid and a live number of bacteria from Lactobacillus casei, L. gasseri. L. johnsonii, L. bulgaricus, L. acidophilus [abstract; 0062; 0065]. Mizusawa discloses that degradation products which are the product of lipase treatment of sunflower oil can be used as the raw material that is fermented with the lactic acid bacteria [0028]. Mizusawa discloses that the unsaturated fatty acids are added before fermentation [0028; 0062]. Mizusawa discloses a fermented dairy food/fermenting milk [0062; 0065]. Mizusawa discloses animal milk as a medium [0029; 0031- 0033]. However, claim 9 is a recitation of the intended use of the claimed invention and in order to patentably distinguish the claimed invention from the prior art, the recitation must result in a structural difference between the claimed invention and the prior art. MPEP 2103 states that intended use language "does not limit a claim to a particular structure does not limit the scope of a claim". The above mentioned phrase does not limit the claim to any particular structure, so it is not interpreted to limit the scope of the claims. If the prior art structure is capable of performing the intended use, then it meets the claim. Mizusawa does not disclose wherein the amount of the lipase degradation product added is 3 to 100 ppm in terms of free fatty acids. Mizusawa does not disclose that the lipase is derived from wherein the lipase degradation product is a degradation product of a lipase at least one of the genus Candida, the genus, Rhizopus, the genus Penicillium, and the genus Aspergillus. Ogasawara discloses a method of making a fermented food product with lactic acid bacteria, L. casei, and including oleic acid (free fatty acid) or its derivatives [col. 6, lines 14-67; claims 8 and 10]. Ogasawara discloses that oleic acid and its derivatives have growth promoting and viability promoting abilities for lactic acid bacteria [abstract; col. 6, lines 14-67; claims 1, 8, and 13]. Ogasawara discloses adding oleic acid at 5 to 50 ppm [col. 6, lines 41-50]. Sande discloses free fatty acids derived from the lipase treatment of oils including olive oil, and sunflower oil [abstract]. Sande discloses the generation of free fatty acids including oleic acid [abstract]. Suganuma discloses treating vegetable oils with lipase [abstract; 0037]. Suganuma discloses sunflower oil [0037]. Suganuma discloses that the lipase can be derived from Rhizopus or Aspergillus [0037]. At the effective filing date of the invention it would have been obvious to one of ordinary skill in the art to modify the method of Mizusawa to include the free fatty acid at 5 to 50 ppm as in Ogasawara in order to aid in the growth and the viability of lactic acid bacteria. It would have been obvious that the sunflower oil of Mizusawa would have produced a lipase degradation product which was a free fatty acid including oleic acid, since Sande discloses oleic acid as a lipase hydrolysis product of sunflower and olive oils. Further it would have been obvious to utilize lipase derived from Rhizopus or Aspergillus as in Suganuma since they are able to degrade plant oils to produce fatty acids. Regarding Claims 14-16: Mizusawa discloses as discussed above in claims 1, 8, and 9. Mizusawa discloses a lipase degradation product of sunflower oil as discussed above. Mizusawa does not disclose that the lipase degradation product is a product of olive oil. Sande discloses free fatty acids derived from the lipase treatment of oils including olive oil, and sunflower oil [abstract]. Sande discloses the generation of free fatty acids including oleic acid [abstract]. At the effective filing date of the invention it would have been obvious to modify the oils of Mizusawa to include olive oil as a source of free fatty acid degradation products as in Sande since Mizusawa discloses generally the inclusion of vegetable oils, sunflower oil, corn, peanut, soy, and since Sande also discloses sunflower oil, corn, peanut, soy, as sources of oils for the degradation product. Response to Arguments The 103(a) rejections of claims 1, 6-9, and 14-16 over Mizusawa et al. (US 2005/0208195) in view of Ogasawara et al. (US 9,708,579) and Sande et al. “Production of omega 3, 6, and 9 fatty acids of hydrolysis of vegetable oils…” Food Sci. Biotechnol 2018 vol. 27 (2) pg. 537-545 have been withdrawn due to the amendments to the claims. Conclusion 8. Any inquiry concerning this communication or earlier communications from the examiner should be directed to FELICIA C TURNER whose telephone number is (571)270-3733. The examiner can normally be reached Mon-Thu 8:00-4:00 pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Emily Le can be reached at 571-272-0903. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /Felicia C Turner/Primary Examiner, Art Unit 1793
Read full office action

Prosecution Timeline

Show 6 earlier events
Apr 21, 2025
Response after Non-Final Action
Jun 13, 2025
Non-Final Rejection mailed — §103
Dec 15, 2025
Response Filed
Dec 15, 2025
Response after Non-Final Action
Mar 02, 2026
Final Rejection mailed — §103
May 28, 2026
Request for Continued Examination
May 31, 2026
Response after Non-Final Action
Jul 29, 2026
Non-Final Rejection mailed — §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
26%
Grant Probability
56%
With Interview (+30.1%)
4y 2m (~0m remaining)
Median Time to Grant
High
PTA Risk
Based on 636 resolved cases by this examiner. Grant probability derived from career allowance rate.

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