Prosecution Insights
Last updated: April 19, 2026
Application No. 17/618,314

MICROBIOTA-DIRECTED FOODS TO REPAIR A SUBJECT'S GUT MICROBIOTA

Non-Final OA §103
Filed
Dec 10, 2021
Examiner
TRAN, LIEN THUY
Art Unit
1793
Tech Center
1700 — Chemical & Materials Engineering
Assignee
International Centre For Diarrhoeal Disease Research Bangladesh
OA Round
5 (Non-Final)
28%
Grant Probability
At Risk
5-6
OA Rounds
4y 3m
To Grant
55%
With Interview

Examiner Intelligence

Grants only 28% of cases
28%
Career Allow Rate
250 granted / 878 resolved
-36.5% vs TC avg
Strong +26% interview lift
Without
With
+26.3%
Interview Lift
resolved cases with interview
Typical timeline
4y 3m
Avg Prosecution
83 currently pending
Career history
961
Total Applications
across all art units

Statute-Specific Performance

§101
1.4%
-38.6% vs TC avg
§103
60.7%
+20.7% vs TC avg
§102
6.1%
-33.9% vs TC avg
§112
24.1%
-15.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 878 resolved cases

Office Action

§103
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Continued Examination Under 37 CFR 1.114 A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous Office action has been withdrawn pursuant to 37 CFR 1.114. Applicant's submission filed on 1/5/26 has been entered. Claim 1 is amended. Claims 1,3-4,7-8,13-15,19-20,55 are pending. The previous 112 first paragraph rejection is withdrawn due to the amendment. Claim Rejections - 35 USC § 103 Claim(s) 1,3-4,7-8,13-15,19-20, 55 is/are rejected under 35 U.S.C. 103 as being unpatentable over Bowman (WO 2018/195220) in view of Huntsman ( 2016/0128367), Yang ( CN 101283789) and Sekiguchi ( WO 2006059541). For claims 1,8 Bowman disclose a composition comprising a protein source, a starch source from flour of plant, vitamin and mineral, nutritious oil and additional flavorings. The composition comprises about 1-20 grams of plant-derived protein per serving. The protein can be provided in the form of a flour and can be selected from combination of chickpea, soy. The starch source is selected from plant flour including peanut flour. The multi-vitamin supplement includes vitamin A, B, D, C and E and minerals includes calcium, copper, iron, magnesium, phosphorus, potassium, zinc and manganese. The composition comprises daily value of essential vitamins and minerals. ( see paragraphs 0023-0024, 0030,0033,0039,0041,0044,0046,0048,0050,0058-0059) For claim 8, the claim does not recite a specific ingredient; the glycan equivalent can be any material in the same class of ingredient. For instance, another legume can be used for chickpea and soy or another nut can be used for peanut. Bowman discloses other legumes and other nuts. The Bowman composition does not contain milk, powdered milk or milk product. For claims 13-14, Bowman discloses the oil including vegetable oil such as canola, coconut, corn, etc.. ( see paragraph 00109) For claim 19, Bowman discloses the oil including animal fat such and the oil can be one or more oil. ( see paragraph 00109). For claim 20, Bowman discloses the composition comprises sugar which is sucrose. ( see paragraph 00105) Bowman does not disclose the kcal, the protein ratio, fat ratio, the fat gram and the inclusion of green banana as in claim 1, the kcal as in claim 3, the ranges as in claim 4, the ratio as in claim 7, and the soybean amount as in claim 15 and the fat ratio as in claim 55. Huntsman discloses stable convenient whole food nutritional supplement. The food includes chickpeas, peanut, legumes, fiber and vitamins and minerals. Huntsman teaches whole food source such as banana can be added. ( see paragraphs 0055, 0056,0015,0007) Yang disclose a method for preparing green banana powder. The banana power is used in flavoring. The green banana is a source of resistant starch which is a dietary fiber. ( see abstract, page 3) Sekiguchi discloses gelatinous food base. Sekiguchi teaches adding flavoring imparting agent including fragrance, fruit etc. Fragrances such as orange, strawberry, banana etc.. can be used. ( see paragraphs 0037, 0038) Bowman teaches other ingredients including flavorings. It would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to add green banana as a flavoring source when such taste is desired. Huntsman shows that banana is added to nutritional food comprising ingredients similar to Bowman. Yang teaches to use green banana powder as flavorings. Sekiguichi discloses to use banana for fragrance and flavoring. The inclusion of green banana would have been an obvious matter of taste preference. One of ordinary skill in the art would also have been motivated to add green banana powder as taught in Yang because it’s a source of resistant starch which is a dietary fiber. The inclusion of green banana further enhances the nutrition of the Bowman food product. Bowman discloses that the food comprises 1-20 gram protein and example 1 on page 31 shows a 100 g serving. Thus, it is obvious the amount of protein is per 100 g serving and the amount of fat in example 1 is 3 gram/100 g serving. Since the protein provides 1-20 gram and including chickpea, soy flour, the protein already falls within the claimed range. Bowman discloses in paragraph 0024 that the composition comprises a daily value of essential vitamins and mineral and discusses the leading causes of hidden hunger at young age. The amount of Kcal, protein and fat ratios can readily be calculated from the macronutrients. It is known carbohydrates provides 4 cal, protein is 4 cal and fat is 9 cal. In example 1 of Bowman, the kcal would be approximate 405kcal for 70.7 gram of carbohydrate, 24 gram of protein and 3 gram of fat. It would have been obvious to one of ordinary skill in the art to determine the kcal depending on the amount of protein, flour, fat and flavoring such as banana included in the composition. It would have been obvious to one of ordinary skill in the art to vary the kcal by varying the amount of fat, protein and other ingredients depending the intended consumer and the nutrition desired to provide. It would have been readily obvious to determine the protein and fat ratio once the kcal is known. It would have been obvious to include the chickpea, peanut flour, soy flour and banana in varying ratio depending on the taste, nutrition, flavor desired. Such parameter can readily be determined by one of ordinary skill in the art through routine experimentation. It would have been obvious to one of ordinary skill in the art to use soybean oil as using a known alternative ingredient to perform the same function of providing a fat source. The amount to use would have been an obvious matter of taste preference. Response to Arguments Applicant’s arguments with respect to claim(s) 1,3-4,7-8,13-15,19-20, 55 have been considered but are moot because the new ground of rejection does not rely on any reference applied in the prior rejection of record for any teaching or matter specifically challenged in the argument. New prior art is added to show the use of banana as flavorings. Applicant continues to argue the exceedingly large number of combination without providing any basis to the calculation. The formula and number given in the previous response is the correct formula for 38 when 2 is selected. Regardless, the point made is not relevant. Even if many possible combinations are possible, the combination of chickpea flour, peanut flour and soy flour is clearly disclosed in Bowman as explained in the rejection. Thus, there is no question of reasonable expectation of success because Bowman discloses the combination of chickpea, peanut flour and soy flour. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to LIEN THUY TRAN whose telephone number is (571)272-1408. The examiner can normally be reached Monday-Thursday. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Emily Le can be reached at 571-272-0903. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. February 2, 2026 /LIEN T TRAN/Primary Examiner, Art Unit 1793
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Prosecution Timeline

Dec 10, 2021
Application Filed
Jul 10, 2024
Non-Final Rejection — §103
Oct 15, 2024
Response Filed
Nov 21, 2024
Final Rejection — §103
Feb 27, 2025
Request for Continued Examination
Feb 28, 2025
Response after Non-Final Action
Apr 29, 2025
Non-Final Rejection — §103
Aug 04, 2025
Response after Non-Final Action
Aug 04, 2025
Response Filed
Oct 02, 2025
Final Rejection — §103
Jan 05, 2026
Request for Continued Examination
Jan 07, 2026
Response after Non-Final Action
Feb 02, 2026
Non-Final Rejection — §103 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12568977
LEAVENING AGENTS
2y 5m to grant Granted Mar 10, 2026
Patent 12568985
MILKFAT OR BUTTERFAT FORMULATIONS
2y 5m to grant Granted Mar 10, 2026
Patent 12564205
A Process for preparing a heat-treated vegetable and/or meat matter.
2y 5m to grant Granted Mar 03, 2026
Patent 12564199
FOOD PRODUCTS WITH SHELLS THAT ARE DISSOLVED OR MELTED TO RELEASE INGREDIENTS AND FORM HEATED BEVERAGES
2y 5m to grant Granted Mar 03, 2026
Patent 12557834
EDIBLE FILMS AND COATINGS EMPLOYING WATER SOLUBLE CORN PROLAMIN AND OTHER FUNCTIONAL INGREDIENTS
2y 5m to grant Granted Feb 24, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
28%
Grant Probability
55%
With Interview (+26.3%)
4y 3m
Median Time to Grant
High
PTA Risk
Based on 878 resolved cases by this examiner. Grant probability derived from career allow rate.

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