Last updated: October 04, 2026

Application No. 18/062,642

Lymphocyte-Based PKCe Test for Alzheimer's Disease

Final Rejection

Filed

Dec 07, 2022

Priority

Mar 31, 2017 — provisional 62/479,663 +2 more

Examiner

NICOL, ALEXANDER W

Art Unit

1634

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Neurodiagnostics LLC

OA Round

5 (Final)

This examiner grants 43% of cases after interview

— +43.1% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 177 resolved cases, 2023–2026

Examiner Intelligence

NICOL, ALEXANDER W View full profile →

Grants 43% of resolved cases

Career Allowance Rate

76 granted / 177 resolved

-17.1% vs TC avg

Strong +43% interview lift

Without

With

+43.1%

Interview Lift

resolved cases with interview

Typical timeline

4y 1m

Avg Prosecution

42 currently pending

Career history

234

Total Applications

across all art units

Statute-Specific Performance

§101

3.0%

-37.0% vs TC avg

§103

41.4%

+1.4% vs TC avg

§102

19.2%

-20.8% vs TC avg

§112

21.1%

-18.9% vs TC avg

Black line = Tech Center average estimate • Based on career data from 177 resolved cases

Prosecution Timeline

Show 4 earlier events

Oct 16, 2024

Request for Continued Examination

Oct 18, 2024

Response after Non-Final Action

Feb 12, 2025

Non-Final Rejection mailed

Aug 11, 2025

Response Filed

Nov 12, 2025

Final Rejection mailed

May 11, 2026

Request for Continued Examination

May 13, 2026

Response after Non-Final Action

Aug 18, 2026

Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/605,149

Patent 12742179

Methods of Treating Rheumatoid Arthritis Using RNA-Guided Genome Editing of HLA Gene

2y 6m to grant Granted Sep 22, 2026

17/415,860

Patent 12728171

COMPLEMENT FACTOR I AND COMPLEMENT FACTOR I COFACTOR, VECTORS ENCODING THEREFOR AND THERAPEUTIC USE

5y 2m to grant Granted Sep 08, 2026

18/936,294

Patent 12716890

MACRO TISSUE EXPLANT, METHODS AND USES THEREFOR

1y 9m to grant Granted Aug 25, 2026

17/395,184

Patent 12668777

CHIMERIC ANTIGEN RECEPTOR T CELLS AND METHODS OF USE THEREOF

4y 11m to grant Granted Jun 30, 2026

17/613,818

Patent 12649952

NTRK FUSION MOLECULES AND USES THEREOF

4y 6m to grant Granted Jun 09, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

6-7

Expected OA Rounds

43%

Grant Probability

86%

With Interview (+43.1%)

4y 1m (~3m remaining)

Median Time to Grant

High

PTA Risk

Based on 177 resolved cases by this examiner. Grant probability derived from career allowance rate.