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Last updated: August 17, 2026

Examiner: NICOL, ALEXANDER W

Tech Center 1600 • Art Units: 1633 1634

This examiner grants 43% of resolved cases

Performance Statistics

42.9%

Allow Rate

-17.1% vs TC avg

232

Total Applications

+43.1%

Interview Lift

1504

Avg Prosecution Days

Based on 177 resolved cases, 2023–2026

Rejection Statute Breakdown

3.1%

§101 Eligibility

19.5%

§102 Novelty

40.9%

§103 Obviousness

21.3%

§112 Clarity

Currently Pending Office Actions

App #	Title	Status	Assignee
18566367	CAS9 NICKASE-MEDIATED GENE EDITING	Non-Final OA	UNIVERSITY OF MASSACHUSETTS
18538799	THERAPEUTIC COMPOSITIONS COMPRISING TRANSCRIPTION FACTORS AND METHODS OF MAKING AND USING THE SAME	Non-Final OA	The Regents of the University of California
18034045	CONTROLLING CELLULAR BEHAVIOR USING FEED-FORWARD CIRCUITS	Final Rejection	The Regents of the University of California
17152463	ADENO-ASSOCIATED VIRAL VECTOR, COMPOSITIONS, METHODS OF PROMOTING MUSCLE REGENERATION, AND TREATMENT METHODS	Final Rejection	NEW YORK UNIVERSITY
17793115	SMALL TYPE II-D CAS PROTEINS AND METHODS OF USE THEREOF	Final Rejection	MASSACHUSETTS INSTITUTE OF TECHNOLOGY
18020029	COMPOSITIONS AND METHODS FOR INCREASING PROTEIN EXPRESSION	Final Rejection	The Hong Kong University of Science and Technology
18252194	EXPRESSION SYSTEM AND METHOD FOR CONTROLLING A NETWORK IN A CELL AND CELL COMPRISING THE EXPRESSION SYSTEM	Final Rejection	ETH ZURICH

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