Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA .
Detailed Action
Claims 1-12,14,16,20,22,24,26,28 and 30 submitted on 6/8/2026 are pending for examination.
Applicants’ argument submitted on 6/8/2026 is considered. Rejections and/or objections not reiterated from previous office actions are hereby withdrawn.
Claim Rejections
35 USC 112(b) Rejection
The following is a quotation of 35 U.S.C. 112(b):
(b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention.
Claims 22, and 24, 26, 28, 30 ( depend on claim 22) is rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor, or for pre-AIA the applicant regards as the invention.
Claim 22 is rejected for being unclear for reciting “conducted in a recombinant cell”. Claim 22 depends on claim 1. Claim 1 recite a method for producing a compound of Formula (II), the method comprising: condensing a compound of Formula (I), or a salt thereof, with coenzyme A (CoA) using an enzyme that is at least 80% identical to the Pm4CL1 amino acid sequence of SEQ ID NO: 1 to produce a compound of Formula (II). It is unclear how a purified Pm4CL1 enzyme of amino acid sequence of SEQ ID NO: 1 obtained and purified from host cell ( see claims 14, 16 ), compound of formula (I) and coenzyme A (CoA) compound will be introduced in a recombinant cell. Claim 1 used isolated and purified enzyme. Correction is required.
Conclusion
Claims 1-12,14,16, 20 are allowed. Claims 22,24,26,28 and 30 are rejected.
Any inquiry concerning this communication or earlier communications from the
examiner should be directed to Mohammad Meah whose telephone number is 571-272-
1261. The examiner can normally be reached on 8:30-5PM.
If attempts to reach the examiner by telephone are unsuccessful, the examiner’s
supervisor, Robert Mondesi can be reached on 4089187584. The fax phone number
for the organization where this application or proceeding is assigned is 571-273-8300.
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/MOHAMMAD Y MEAH/Examiner, Art Unit 1652
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