Prosecution Insights
Last updated: August 18, 2026

Whitehead Institute for Biomedical Research

9 pending office actions • 7 art units • 9 examiners • 0 of 9 (0%) have an AI response strategy ready • 5 patents granted in the last 365 days

Portfolio Summary

9
Total Pending OAs
7
Non-Final OAs
2
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 2 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

1
Overdue
0
Due this week
1
Due this month
0
Due in next 60 days
0
Due later

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

5
Hard (56%)
2
Medium (22%)
2
Easy (22%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other1 (11%)
§103 only2 (22%)
§112 only2 (22%)
Multi-statute (no §101)4 (44%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

8
Life Sciences
89% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
11% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

90 h
Manual time on pending OAs
18 h
Time saved (low, 20%)
31 h
Time saved (mid, 35%)
0.8 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
LEE, JAE W 1 65.6% +39.0%
NOBLE, MARCIA STEPHENS 1 67.0% +40.3%
GROOMS, TIFFANY NICOLE 1 58.8% +46.8%
BUCHANAN, BAILEY CHEYENNE 1 47.6% +50.0%
YOUTCHOM PENDIE, EMMANUEL LED 1 55.6% +50.0%
HUDSON, AMY ROSE 1 75.0% +11.4%
DHAR, MATASHA 1 43.8% +47.5%
PERREIRA, MELISSA JEAN 1 52.0% +25.9%
VIVLEMORE, TRACY ANN 1 73.0% +6.7%

Hard Cases (5)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
17217612 Transcription Factor Trapping by RNA in Gene Regulatory Elements VIVLEMORE, TRACY ANN 28d
18773428 METHODS OF EDITING DNA METHYLATION LEE, JAE W
18386551 CHROMOSOME NEIGHBORHOOD STRUCTURES AND METHODS RELATING THERETO GROOMS, TIFFANY NICOLE
18038943 MODULATING TRANSCRIPTIONAL CONDENSATES BUCHANAN, BAILEY CHEYENNE
17878774 CDC20 VARIANTS RESISTANT TO ANTI-MITOTIC DRUGS AND RELATED METHODS AND COMPOSITIONS YOUTCHOM PENDIE, EMMANUEL LED

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17869611 METHODS FOR LABELING AND TARGETING CELLS HUDSON, AMY ROSE 124d overdue
18773428 METHODS OF EDITING DNA METHYLATION LEE, JAE W
18635153 METHODS FOR REPROGRAMMING SOMATIC CELLS NOBLE, MARCIA STEPHENS
18386551 CHROMOSOME NEIGHBORHOOD STRUCTURES AND METHODS RELATING THERETO GROOMS, TIFFANY NICOLE
18038943 MODULATING TRANSCRIPTIONAL CONDENSATES BUCHANAN, BAILEY CHEYENNE
17878774 CDC20 VARIANTS RESISTANT TO ANTI-MITOTIC DRUGS AND RELATED METHODS AND COMPOSITIONS YOUTCHOM PENDIE, EMMANUEL LED
17588038 IN VIVO GUIDE RNA LIBRARIES AND METHODS OF MAKING THE SAME DHAR, MATASHA
17611560 METHODS OF CHARACTERIZING AND UTILIZING AGENT-CONDENSATE INTERACTIONS PERREIRA, MELISSA JEAN

Top Art Units

Art UnitApps
1632 2
1637 1
1682 1
1647 1
1636 1
1618 1
1638 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18773428 METHODS OF EDITING DNA METHYLATION LEE, JAE W §103§112 Non-Final OA Pending Jul 15, 2024
18635153 METHODS FOR REPROGRAMMING SOMATIC CELLS NOBLE, MARCIA STEPHENS 1632 §112 Non-Final OA Pending Apr 15, 2024
18386551 CHROMOSOME NEIGHBORHOOD STRUCTURES AND METHODS RELATING THERETO GROOMS, TIFFANY NICOLE 1637 §102§103§112 Non-Final OA Pending Nov 02, 2023
18038943 MODULATING TRANSCRIPTIONAL CONDENSATES BUCHANAN, BAILEY CHEYENNE 1682 §102§103§112 Non-Final OA Pending May 25, 2023
17878774 CDC20 VARIANTS RESISTANT TO ANTI-MITOTIC DRUGS AND RELATED METHODS AND COMPOSITIONS YOUTCHOM PENDIE, EMMANUEL LED 1647 §102§103 Non-Final OA Pending Aug 01, 2022
17869611 METHODS FOR LABELING AND TARGETING CELLS HUDSON, AMY ROSE 1636 §112 Final Rejection 124d overdue Pending Jul 20, 2022
17588038 IN VIVO GUIDE RNA LIBRARIES AND METHODS OF MAKING THE SAME DHAR, MATASHA 1632 §103 Non-Final OA Pending Jan 28, 2022
17611560 METHODS OF CHARACTERIZING AND UTILIZING AGENT-CONDENSATE INTERACTIONS PERREIRA, MELISSA JEAN 1618 §103 Non-Final OA Pending Nov 15, 2021
17217612 Transcription Factor Trapping by RNA in Gene Regulatory Elements VIVLEMORE, TRACY ANN 1638 §101§102§103§112 Final Rejection 28d Pending Mar 30, 2021

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