Last updated: July 05, 2026

Application No. 18/441,627

MYELINATION STIMULATOR COMPOUNDS, AND METHODS OF TREATMENT

Non-Final OA

Filed

Feb 14, 2024

Priority

May 11, 2018 — provisional 62/670,221 +2 more

Examiner

VALENROD, YEVGENY

Art Unit

1628

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

University of Florida Research Foundation Inc.

OA Round

1 (Non-Final)

Interview Optional

— +25.4% interview lift. Interview already conducted in this application's prosecution history. This examiner has a 73% grant rate with +25.4% interview lift. Since an interview has already been tried, recommend written response with narrowed claims based on precedent claim evolution patterns.

Based on 1011 resolved cases, 2023–2026

Examiner Intelligence

VALENROD, YEVGENY View full profile →

Grants 73% — above average

Career Allowance Rate

734 granted / 1011 resolved

+12.6% vs TC avg

Strong +25% interview lift

Without

With

+25.4%

Interview Lift

resolved cases with interview

Typical timeline

2y 6m

Avg Prosecution

42 currently pending

Career history

1048

Total Applications

across all art units

Statute-Specific Performance

§101

1.1%

-38.9% vs TC avg

§103

48.5%

+8.5% vs TC avg

§102

13.5%

-26.5% vs TC avg

§112

7.6%

-32.4% vs TC avg

Black line = Tech Center average estimate • Based on career data from 1011 resolved cases

Prosecution Timeline

Feb 14, 2024

Application Filed

Apr 01, 2026

Non-Final Rejection mailed

Jun 24, 2026

Examiner Interview Summary

Jun 24, 2026

Applicant Interview (Telephonic)

Precedent Cases

Applications granted by this same examiner with similar technology

17/917,194

Patent 12661355

COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION

3y 8m to grant Granted Jun 23, 2026

17/839,169

Patent 12611402

COMPOUNDS AND THEIR USE FOR THE TREATMENT OF ALPHA1-ANTITRYPSIN DEFICIENCY

3y 10m to grant Granted Apr 28, 2026

18/057,918

Patent 12611391

MATERIALS AND METHODS FOR IMPROVING LUNG FUNCTION AND FOR PREVENTION AND/OR TREATMENT OF RADIATION-INDUCED LUNG COMPLICATIONS

3y 5m to grant Granted Apr 28, 2026

17/782,441

Patent 12605374

METHODS FOR DRUG SCREENING AND COMPOSITIONS USEFUL FOR THE INHIBITION OF CELL PROLIFERATION AND/OR CELL SURVIVAL

3y 10m to grant Granted Apr 21, 2026

18/027,990

Patent 12590100

TETRAHYDRO-SPIROINDOLINE-PYRROLOPYRROLE-TRIONES INHIBITORS OF THE NRF2-BETA-TRCP INTERACTION FOR USE IN THE TREATMENT OF FATTY LIVER DISEASE

3y 0m to grant Granted Mar 31, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2

Expected OA Rounds

73%

Grant Probability

98%

With Interview (+25.4%)

2y 6m (~1m remaining)

Median Time to Grant

Low

PTA Risk

Based on 1011 resolved cases by this examiner. Grant probability derived from career allowance rate.