Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
109 pending office actions • 52 art units • 103 examiners • 0 of 109 (0%) have an AI response strategy ready • 139 patents granted in the last 365 days
University of Florida Research Foundation Inc. currently manages 109 pending office actions within the Biotechnology & Pharmaceuticals technology area. These 109 actions are distributed across 103 distinct examiners, which indicates a very high degree of individual examiner variety. The involvement of 53 distinct art units further suggests that the company's intellectual property is spread across a wide range of specialized technical groups within the patent office.
The busiest examiner for this portfolio is Johnson, Emily Katharine, who is currently handling 2 of the pending office actions. This small concentration of 2 actions with a single individual means that the vast majority of the portfolio is being reviewed by examiners who are only handling a single case for the entity. For practitioners, this decentralized environment requires a highly adaptable prosecution strategy, as 103 distinct examiners will likely bring a diverse array of perspectives and requirements.
With 53 distinct art units involved, the Biotechnology & Pharmaceuticals filings are subject to many different procedural standards. The 109 pending office actions reflect a broad research and development base that necessitates familiarity with numerous examination units. While Johnson, Emily Katharine and her 2 pending actions represent the busiest point of contact, the overall success of the portfolio depends on navigating the 103 distinct examiners assigned to the various cases.
Based on the USPTO statutory response window for each pending office action. 29 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 29 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 2 (2%) |
| §101 + other | 11 (10%) |
| §103 only | 26 (24%) |
| §102 only | 3 (3%) |
| §112 only | 10 (9%) |
| Double-patenting + other | 16 (15%) |
| Multi-statute (no §101) | 41 (38%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| JOHNSON, EMILY KATHARINE | 2 | 87.5% | +21.9% |
| RYAN, DOUGLAS CHARLES | 2 | 39.2% | +47.6% |
| ROBINSON, HOPE A | 2 | 67.7% | +43.1% |
| KONOPKA, CATHERINE ANNE | 2 | 58.1% | +65.0% |
| NGUYEN, QUANG | 2 | 38.0% | +52.6% |
| PENNINGTON, KATIE LEIGH | 2 | 29.7% | +60.0% |
| PUTTLITZ, KARL J | 1 | 69.1% | +18.6% |
| SILVA, MICHAEL THOMAS | 1 | 33.0% | +23.9% |
| AGGER, ELIZABETH ROSE | 1 | 95.2% | -0.9% |
| INAM, SAHAR | 1 | 100.0% | +0.0% |
Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 19025487 | SELF-DESTRUCTIVE POLYMORPHIC LATCH FOR ERASING DATA STORED IN VOLATILE MEMORY DURING PHYSICAL ATTACKS | AGGER, ELIZABETH ROSE | — |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18552486 | PREDICTION OF POST-OPERATIVE PAIN USING HOSVD | STONE, RACHAEL SOJIN | 77d overdue |
| 17772266 | GENE THERAPY VECTORS | PENNINGTON, KATIE LEIGH | 51d overdue |
| 18316064 | DISTRIBUTED LEDGER PLATFORM FOR ELECTRONIC VOTING AND/OR POLLING | LEE, CLAY C | 35d overdue |
| 18191790 | AAV-BASED GENE THERAPY FOR MULTIPLE SCLEROSIS | NGUYEN, QUANG | 9d overdue |
| 16340738 | METHOD AND APPARATUS FOR IMPROVED DETERMINATION OF NODE INFLUENCE IN A NETWORK | LIU, GUOZHEN | 9d overdue |
| 19094455 | SYSTEMS AND METHODS FOR AUTOMATED BUILDING CODE CONFORMANCE | SITTNER, MATTHEW T | 5d overdue |
| 18013954 | EXERGY-BASED LIFE CYCLE ASSESSMENT OF BUILDINGS | YESILDAG, MEHMET | 5d overdue |
| 17788519 | IMMUNOTHERAPY FOR DIRECT REPROGRAMMING OF CANCER CELLS INTO IMMUNE CELLS/ANTIGEN PRESENTING CELLS/DENDRITIC CELLS | DACE DENITO, ALEXANDRA GERALDINE | 9d |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17772266 | GENE THERAPY VECTORS | PENNINGTON, KATIE LEIGH | 51d overdue |
| 18191790 | AAV-BASED GENE THERAPY FOR MULTIPLE SCLEROSIS | NGUYEN, QUANG | 9d overdue |
| 18267144 | METHOD FOR PROGRAMMABLE CONTROL OF RNA TRANSCRIPT LEVELS WITH AUTOREGULATED CRISPR-CAS13D | KONOPKA, CATHERINE ANNE | 20d |
| 18840617 | Compositions and Methods for Suppression of Flowering in Sugarcane and Energycane | JOHNSON, EMILY KATHARINE | 39d |
| 19682032 | COMPOSITIONS FOR TARGETING MUSCLE CELLS AND USES THEREOF | PUTTLITZ, KARL J | — |
| 19324860 | VEHICLE SECURITY ANALYSIS PLATFORM | SILVA, MICHAEL THOMAS | — |
| 18706881 | IMPROVED GENETIC TRANSFORMATION BY IMPROVING DE-NOVO SHOOT REGENERATION IN ADULT PLANTS AND DURING IN-VITRO TISSUE CULTURE | JOHNSON, EMILY KATHARINE | — |
| 18692438 | AAVRH74 PARTICLES FOR GENE THERAPY OF MUSCLE DISEASE | RYAN, DOUGLAS CHARLES | — |
| Art Unit | Apps |
|---|---|
| 1662 | 5 |
| 1635 | 5 |
| 1634 | 4 |
| 1631 | 4 |
| 1643 | 3 |
| 1645 | 3 |
| 1636 | 3 |
| 1633 | 2 |
| 1637 | 2 |
| 1652 | 2 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19682032 | COMPOSITIONS FOR TARGETING MUSCLE CELLS AND USES THEREOF | PUTTLITZ, KARL J | 1646 | §103§112 | Non-Final OA | — | Pending | May 19, 2026 |
| 19324860 | VEHICLE SECURITY ANALYSIS PLATFORM | SILVA, MICHAEL THOMAS | 3663 | §103§112 | Non-Final OA | — | Pending | Sep 10, 2025 |
| 19025487 | SELF-DESTRUCTIVE POLYMORPHIC LATCH FOR ERASING DATA STORED IN VOLATILE MEMORY DURING PHYSICAL ATTACKS | AGGER, ELIZABETH ROSE | — | §103 | Non-Final OA | — | Pending | Jan 16, 2025 |
| 18874975 | THIAZOLIDINEDIONES FOR THE TREATMENT OF MUSCULAR DYSTROPHIES | INAM, SAHAR | — | §102§112 | Non-Final OA | — | Pending | Dec 13, 2024 |
| 18870030 | CELL-FREE DNA CONCENTRATION IN HYPOTHERMIC MACHINE PERFUSATE AS A RAPID MARKER FOR KIDNEY GRAFT QUALITY | TIWARI, VYOMA SHUBHAM | — | §103§112 | Non-Final OA | — | Pending | Nov 27, 2024 |
| 18865936 | APPARATUS AND METHOD FOR DETERMINING STIMULATION PARAMETERS FOR DEEP BRAIN STIMULATION (DBS) | WEHRHEIM, LINDSEY GAIL | — | §102 | Non-Final OA | — | Pending | Nov 14, 2024 |
| 18912748 | MATERIALS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF CANCER | SKOKO III, JOHN JOSEPH | 1643 | §103§112DP | Non-Final OA | — | Pending | Oct 11, 2024 |
| 18884901 | SITE-SPECIFIC INTEGRATING RECOMBINANT AAV VECTORS FOR GENE THERAPY AND IMPROVED PRODUCTION METHODS | JOHNSON, ALLISON MARIE | — | §102§112 | Non-Final OA | — | Pending | Sep 13, 2024 |
| 18840617 | Compositions and Methods for Suppression of Flowering in Sugarcane and Energycane | JOHNSON, EMILY KATHARINE | 1662 | §103§112 | Final Rejection | 39d | Pending | Aug 22, 2024 |
| 18835859 | SMALL MOLECULES CXCR4 AGONISTS, METHOD OF SYNTHESIS, AND METHOD OF USE | WELLS, LAUREN QUINLAN | — | §102§103§112 | Non-Final OA | — | Pending | Aug 05, 2024 |
| 18728925 | PROCESS FOR SYNTHESIS OF GALBULIMIMA ALKALOID 18 AND COMPOUNDS USEFUL AS OPIOID RECEPTOR ANTAGONISTS AND AGONISTS | YOUNGBLOOD, WILLIAM JUSTIN | — | §112 | Non-Final OA | — | Pending | Jul 15, 2024 |
| 18720572 | DISCOVERY OF PIPERLONGUMINE AS A NOVEL E3 LIGASE LIGAND | CORNET, JEAN P | — | §103§112 | Non-Final OA | — | Pending | Jun 14, 2024 |
| 18717509 | BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS | AULAKH, CHARANJIT | — | §112 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18716013 | METHOD, APPARATUS, AND SYSTEM FOR REMOVAL OF LESIONS | TEMPLETON, MARINA DELANEY | 3794 | §102§103 | Non-Final OA | — | Pending | Jun 03, 2024 |
| 18707248 | Controlling Citrus Huanglongbing (HLB) by Mitigating Cell Death of the Phloem Tissues Caused by Candidatus Liberibacter Asiaticus (CLas) By Suppressing Reactive Oxygen Species (ROS) | MEYER, GEORGE WILLIAM | 1662 | §103§112 | Non-Final OA | — | Pending | May 03, 2024 |
| 18706881 | IMPROVED GENETIC TRANSFORMATION BY IMPROVING DE-NOVO SHOOT REGENERATION IN ADULT PLANTS AND DURING IN-VITRO TISSUE CULTURE | JOHNSON, EMILY KATHARINE | 1662 | §102§103§112 | Final Rejection | — | Pending | May 02, 2024 |
| 18706176 | AAV-MEDIATED THERAPIES FOR VISION LOSS ASSOCIATED WITH FRIEDREICH’S ATAXIA | LARA, CAROLINE MONSERRAT | 1633 | §103DP | Non-Final OA | — | Pending | Apr 30, 2024 |
| 18704712 | SMALL MOLECULE DEGRADATION METHODS FOR TREATING ALS/FTD | ROCHELLE, CIERRA MARIE | — | §112DP | Non-Final OA | — | Pending | Apr 25, 2024 |
| 18623087 | CYANOBACTERIAL HOSTS AND METHODS FOR PRODUCING CHEMICALS | MORGAN, BAILEY MICHELLE | 1645 | §103DP | Non-Final OA | — | Pending | Apr 01, 2024 |
| 18696085 | GENE THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY | RAHMAN, MASUDUR | — | §102§103 | Non-Final OA | — | Pending | Mar 27, 2024 |
| 18693658 | BIOMARKER REFLECTANCE SIGNATURES FOR DISEASE DETECTION AND CLASSIFICATION | KORANG-BEHESHTI, YOSSEF | — | §101§102§103 | Non-Final OA | — | Pending | Mar 20, 2024 |
| 18692438 | AAVRH74 PARTICLES FOR GENE THERAPY OF MUSCLE DISEASE | RYAN, DOUGLAS CHARLES | — | §101§102§103 | Non-Final OA | — | Pending | Mar 15, 2024 |
| 18692493 | AAV PARTICLES WITH MODIFIED INVERTED TERMINAL REPEATS FOR ENHANCED GENE EXPRESSION IN MUSCLE | SMALL, KATHERINE R | 1633 | §102§103 | Non-Final OA | — | Pending | Mar 15, 2024 |
| 18595698 | DYNAMIC REFINEMENT OF HARDWARE ASSERTION CHECKERS | LIN, ARIC | — | §102§103 | Non-Final OA | — | Pending | Mar 05, 2024 |
| 18686633 | RADIATION COMPATIBLE EXPANDER FOR BREAST RECONSTRUCTION | FLORES, ADRIAN | 3774 | §102§103 | Non-Final OA | — | Pending | Feb 26, 2024 |
| 18293040 | ENGINEERING AAV VECTORS WITH IMPROVED CNS TARGETING | BARRON, SEAN C | 1653 | §103 | Non-Final OA | — | Pending | Jan 29, 2024 |
| 18290734 | CONTROLLING PRO-INFLAMMATORY MACROPHAGE PHENOTYPE THROUGH BIOFUNCTIONAL HYDROGEL DESIGN | BEANE, RANDALL L | — | §103§112 | Non-Final OA | — | Pending | Jan 19, 2024 |
| 18288301 | SYNTHETIC AAV VECTORS FOR REPEATED DELIVERY OF THERAPEUTIC GENES | KNIGHT, TERESA E | 1634 | §102 | Non-Final OA | — | Pending | Oct 25, 2023 |
| 18287711 | AAVRH74 VECTORS FOR GENE THERAPY OF MUSCULAR DYSTROPHIES | SULLIVAN, STEPHANIE LAUREN | 1635 | §103§112DP | Non-Final OA | — | Pending | Oct 20, 2023 |
| 18287690 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | BARSKY, JARED | 1628 | §102§112DP | Non-Final OA | — | Pending | Oct 20, 2023 |
| 18287368 | AGENTS FOR MANUFACTURE OF CO-ASSEMBLING PEPTIDES | JAUHARI, SACHI | 1654 | §103§112 | Non-Final OA | — | Pending | Oct 18, 2023 |
| 18286450 | EXOSOME GENE THERAPY FOR TREATING INNER EAR DISEASE | LIPPOLIS, ALEXANDRA ROSE | 1637 | §102§103§112 | Non-Final OA | — | Pending | Oct 11, 2023 |
| 18484830 | WIRELESS CHARGING AND NEAR-FIELD COMMUNICATION (NFC) INTEGRATION | FANTU, YALKEW | — | §103 | Non-Final OA | — | Pending | Oct 11, 2023 |
| 18552486 | PREDICTION OF POST-OPERATIVE PAIN USING HOSVD | STONE, RACHAEL SOJIN | 3681 | §101§103 | Non-Final OA | 77d overdue | Pending | Sep 26, 2023 |
| 18236078 | PROTEIN-PEG INTERACTIONS THAT REDIRECT THE THERMAL UNFOLDING PATHWAY OF PEGYLATED HUMAN GALECTIN-3C | ROBINSON, HOPE A | 1652 | §102§103§112 | Non-Final OA | — | Pending | Aug 21, 2023 |
| 18031505 | SELF-ASSEMBLING URICASE FUSION PEPTIDES | MOEHLMAN, ANDREW TERRY | 1655 | §103§112 | Final Rejection | 41d | Pending | Aug 18, 2023 |
| 18451509 | SPATIO-TEMPORAL INTELLIGENT DIGITAL MEMORY SYSTEMS AND METHODS | COLEMAN, PAUL | 2126 | §103 | Final Rejection | — | Pending | Aug 17, 2023 |
| 18271769 | SYNERGISTIC MIXTURES COMPRISING PYRETHRUM FOR ARTHROPOD TOXICITY AND REPELLENCY | MELLER, MICHAEL V | 1655 | §101§102§103 | Final Rejection | — | Pending | Jul 11, 2023 |
| 18271584 | ANTICANCER COMPOUNDS AND USES THEREOF | BENAVIDES, JENNIFER ANN | 1675 | §112 | Final Rejection | — | Pending | Jul 10, 2023 |
| 18268280 | CREATE HUANGLONGBING TOLERANCE BY SILENCING A CITRUS NEGATIVE IMMUNE REGULATOR | DELEO, VICTORIA LYNN | 1662 | §102§103 | Non-Final OA | — | Pending | Jun 19, 2023 |
| 18267144 | METHOD FOR PROGRAMMABLE CONTROL OF RNA TRANSCRIPT LEVELS WITH AUTOREGULATED CRISPR-CAS13D | KONOPKA, CATHERINE ANNE | 1635 | §103§112 | Final Rejection | 20d | Pending | Jun 14, 2023 |
| 18257237 | DIPHENHYDRAMINE AND LACTOFERRIN FOR PREVENTION AND TREATMENT OF COVID-19 | COFFA, SERGIO | 1658 | §103DP | Final Rejection | 56d | Pending | Jun 13, 2023 |
| 18327296 | FUNCTIONAL VERIFICATION FLOW OF OBFUSCATED DESIGNS FOR CIRCUITS | NGUYEN, NHA T | 2851 | §103 | Final Rejection | — | Pending | Jun 01, 2023 |
| 18038321 | USE OF INSULIN-LIKE GROWTH FACTORS WITH GAMMA-CHAIN CYTOKINES TO INDUCE HOMEOSTATIC PROLIFERATION OF LYMPHOCYTES | SULLIVAN, DENNIS JOHN | 1642 | §103 | Non-Final OA | — | Pending | May 23, 2023 |
| 18037364 | MULTIFUNCTION MICROFLUIDIC OPTRODE | ROANE, AARON F | 3796 | §102 | Non-Final OA | — | Pending | May 17, 2023 |
| 18253010 | Modified Insecticidal Proteins | MEADOWS, CHRISTINA L | 1663 | §112 | Final Rejection | 35d overdue | Pending | May 15, 2023 |
| 18316064 | DISTRIBUTED LEDGER PLATFORM FOR ELECTRONIC VOTING AND/OR POLLING | LEE, CLAY C | 3699 | §101§103 | Final Rejection | 35d overdue | Pending | May 11, 2023 |
| 18314773 | USE OF AAV-EXPRESSED M013 PROTEIN AS AN ANTI-INFLAMMATORY THERAPEUTIC | NGUYEN, QUANG | 1631 | §103§112 | Non-Final OA | — | Pending | May 09, 2023 |
| 18305971 | DETECTING AUDIO DEEPFAKES THROUGH ACOUSTIC PROSODIC MODELING | BECKER, TYLER JUSTIN | 2657 | §103 | Final Rejection | 28d | Pending | Apr 24, 2023 |
| 18032648 | METHOD FOR TREATING ALS/FTD THROUGH DEGRADATION OF RNA REPEAT EXPANSION | TOWNSLEY, SARA ELIZABETH | 1629 | §112 | Final Rejection | 15d overdue | Pending | Apr 19, 2023 |
| 18191790 | AAV-BASED GENE THERAPY FOR MULTIPLE SCLEROSIS | NGUYEN, QUANG | 1631 | §103§112 | Final Rejection | 9d overdue | Pending | Mar 28, 2023 |
| 18028937 | CANNABIS PLANT DERIVED EXTRACELLULAR VESICLES AND THERAPEUTIC METHODS USING THE SAME | LEE, SIN J | 1613 | §103§112 | Final Rejection | — | Pending | Mar 28, 2023 |
| 18026389 | COMPOSITIONS AND METHODS FOR MODULATION OF BACTERIAL GENE EXPRESSION | RYAN, DOUGLAS CHARLES | 1635 | §112 | Non-Final OA | — | Pending | Mar 15, 2023 |
| 18178819 | CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF | DUFFY, PATRICIA ANN | 1645 | §112 | Final Rejection | — | Pending | Mar 06, 2023 |
| 18042424 | SILK PARTICLES ENCAPSULATING OXYGEN CARRIERS AS ARTIFICIAL BLOOD SUBSTITUTE | JANOSKO, CHASITY PAIGE | 1613 | §103 | Non-Final OA | — | Pending | Feb 21, 2023 |
| 18017726 | IMPROVED AAV-MEDIATED X-LINKED RETINOSCHISIS THERAPIES | ALLEN, MICHAEL D | 1671 | §103 | Final Rejection | — | Pending | Jan 24, 2023 |
| 17924539 | DISEASE CORRECTION BY DELIVERY OF AAV8 VECTORS EXPRESSING CODON OPTIMIZED NAGLU | PENNINGTON, KATIE LEIGH | 1634 | §103 | Final Rejection | — | Pending | Nov 10, 2022 |
| 17919052 | ENHANCED EFFECTS OF GENE-IMMUNOTHERAPY AND IMMUNOSUPPRESSANTS IN MULTIPLE SCLEROSIS | SHIBUYA, MARK LANCE | 1631 | §103Other | Non-Final OA | 3d overdue | Pending | Oct 14, 2022 |
| 18045873 | AAV VARIANTS WITH HOST ANTIBODY ESCAPE CAPABILITIES AND ALTERED TISSUE TARGETING PROPERTIES | KONOPKA, CATHERINE ANNE | 1635 | §103DP | Final Rejection | — | Pending | Oct 12, 2022 |
| 18045563 | AUTOMATED CYBERATTACK DETECTION USING TIME-SEQUENTIAL DATA, EXPLAINABLE MACHINE LEARNING, AND/OR ENSEMBLE BOOSTING FRAMEWORKS | LIN, SHERMAN L | 2447 | §103 | Non-Final OA | 22d | Pending | Oct 11, 2022 |
| 17911026 | METHODS, DEVICES, AND COMPOSITIONS FOR LESION REPAIR AND PREVENTION | NGUYEN, NGOC-ANH THI | 1615 | §103 | Non-Final OA | — | Pending | Sep 12, 2022 |
| 17910327 | AFFINITY MATURED AND HUMANIZED BINDING DOMAINS TARGETING ROR2 | BRISTOL, LYNN ANNE | 1643 | §112 | Non-Final OA | — | Pending | Sep 08, 2022 |
| 17800687 | Multilamellar RNA Nanoparticles and Methods of Sensitizing Tumors to Treatment with Immune Checkpoint Inhibitors | ZOU, NIANXIANG | 1671 | §103§112DP | Non-Final OA | 19d overdue | Pending | Aug 18, 2022 |
| 17788519 | IMMUNOTHERAPY FOR DIRECT REPROGRAMMING OF CANCER CELLS INTO IMMUNE CELLS/ANTIGEN PRESENTING CELLS/DENDRITIC CELLS | DACE DENITO, ALEXANDRA GERALDINE | 1636 | §103§112Other | Non-Final OA | 9d | Pending | Jun 23, 2022 |
| 17772266 | GENE THERAPY VECTORS | PENNINGTON, KATIE LEIGH | 1634 | §102§103§112 | Non-Final OA | 51d overdue | Pending | Apr 27, 2022 |
| 17762543 | VACCINE THERAPY FOR RAN PROTEIN DISEASES | WANG, CHANG YU | 1675 | §102DP | Non-Final OA | 35d | Pending | Mar 22, 2022 |
| 17635631 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | CHENG, KAREN | 1623 | §102§103§112 | Non-Final OA | 26d | Pending | Feb 15, 2022 |
| 17630843 | SYNERGISTIC MIXTURES FOR ARTHROPOD TOXICITY AND REPELLENCY | PURDY, KYLE A | 1611 | §103§112 | Final Rejection | — | Pending | Jan 27, 2022 |
| 17584505 | MACHINE LEARNING DEVELOPMENT USING SUFFICIENTLY-LABELED DATA | DIEP, DUY T | 2123 | §103 | Final Rejection | 27d | Pending | Jan 26, 2022 |
| 17575762 | CHIMERIC ANTIGEN RECEPTOR COMPRISING INTERLEUKIN-15 INTRACELLULAR DOMAIN AND USES THEREOF | DUFFY, BRADLEY | 1643 | §103 | Final Rejection | — | Pending | Jan 14, 2022 |
| 17621029 | STRUCTURALLY DEFINED SIRNA-DUAL VARIABLE DOMAIN IMMUNOGLOBULIN CONJUGATES | TRAN, CHRISTINA L | 1637 | §112 | Non-Final OA | — | Pending | Dec 20, 2021 |
| 17540121 | RAAV-GUANYLATE CYCLASE COMPOSITIONS AND METHODS FOR TREATING LEBER'S CONGENITAL AMAUROSIS-1 (LCA1) | MOLOYE, TITILAYO | 1632 | §112DP | Non-Final OA | 21d | Pending | Dec 01, 2021 |
| 17603302 | MODIFIED AAV VECTORS THAT DAMPEN THE HUMORAL IMMUNE RESPONSE | WANG, RUIXUE | 1672 | §103 | Non-Final OA | 31d overdue | Pending | Oct 12, 2021 |
| 17428749 | METHODS FOR TARGETED TREATMENT AND PREDICTION OF PATIENT SURVIVAL IN CANCER | HAMMELL, NEIL P | 1681 | §101§103§112 | Non-Final OA | — | Pending | Aug 05, 2021 |
| 17428722 | CORE MASTER REGULATORS OF GLIOBLASTOMA STEM CELLS | MEYERING, SHABANA SHABBEER | 1635 | §103§112 | Non-Final OA | — | Pending | Aug 05, 2021 |
| 17228298 | ENGINEERED RECEPTOR/LIGAND SYSTEM FOR DELIVERY OF THERAPEUTIC AGENTS | ZAHORIK, AMANDA MARY | 1636 | §103§112 | Final Rejection | — | Pending | Apr 12, 2021 |
| 17272203 | ADENO-ASSOCIATED VIRAL VECTORS FOR THE TREATMENT OF BEST DISEASE | BATES, KEENAN ALEXANDER | 1631 | §102§103§112 | Non-Final OA | — | Pending | Feb 26, 2021 |
| 16972740 | AAV CARDIAC GENE THERAPY FOR CARDIOMYOPATHY | SU-TOBON, QIWEN NMN | 1636 | §103DP | Non-Final OA | — | Pending | Dec 07, 2020 |
| 16340738 | METHOD AND APPARATUS FOR IMPROVED DETERMINATION OF NODE INFLUENCE IN A NETWORK | LIU, GUOZHEN | 1686 | §101§103§112Other | Final Rejection | 9d overdue | Pending | Apr 10, 2019 |
| 19220933 | METHODS AND COMPOSITIONS FOR PLANT PATHOGEN RESISTANCE IN PLANTS | ZHONG, WAYNESHAOBIN | — | §112 | Non-Final OA | — | Pending | May 28, 2025 |
| 19094455 | SYSTEMS AND METHODS FOR AUTOMATED BUILDING CODE CONFORMANCE | SITTNER, MATTHEW T | 3629 | §101§103§112 | Final Rejection | 5d overdue | Pending | Mar 28, 2025 |
| 19100617 | COMPOSITIONS, KITS, METHODS, AND METHODS OF ADMINISTRATION RELATING TO EDWARDSIELLA PISCICIDA VACCINE AND/OR ANTIGEN DELIVERY VECTOR SYSTEMS | HAUK TEODORO, PRICILA NMN | 1645 | §102§103 | Non-Final OA | — | Pending | Feb 03, 2025 |
| 19037772 | LEARNING MEMORY SYSTEMS AND METHODS | DARE, RYAN A | 2132 | §101 | Final Rejection | — | Pending | Jan 27, 2025 |
| 19020470 | AI-ASSISTED CODE COMPLIANCE CHECKING FOR BUILDING AND LAND DEVELOPMENT | BEARD, CHARLES LLOYD | — | §103Other | Non-Final OA | — | Pending | Jan 14, 2025 |
| 18949297 | METHODS AND COMPOSITIONS FOR MINIMIZING X-RAY SCATTERING ARTIFACTS | VETERE, ROBERT A | 1712 | §102§103§112DP | Final Rejection | 30d | Pending | Nov 15, 2024 |
| 18837232 | ONE-POT ENDONUCLEOLYTICALLY EXPONENTIATED ROLLING CIRCLE AMPLIFICATION BY CRISPR-CAS12a | KIM, YOUNG J | — | §102§103§112 | Non-Final OA | — | Pending | Aug 09, 2024 |
| 18782144 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | COUGHLIN, MATTHEW P | — | §102§112DP | Non-Final OA | — | Pending | Jul 24, 2024 |
| 18640036 | METHODS AND COMPOSITIONS FOR IONTOPHORETIC DRUG DELIVERY TO THE EYE | ULSH, DUNG T | — | §102§103§112 | Non-Final OA | — | Pending | Apr 19, 2024 |
| 18701456 | Insect Toxin Delivery Mediated by a Begomovirus Coat Protein | CHATTERJEE, JAYANTA | 1662 | §103DP | Final Rejection | 33d | Pending | Apr 15, 2024 |
| 18691666 | CELLULAR THERAPY TO SUPPRESS IMMUNE RESPONSE | METCALF, MATTHEW CURRAN | — | §102§103 | Non-Final OA | — | Pending | Mar 13, 2024 |
| 18689470 | NOVEL COMPOUNDS FOR MANAGEMENT OF BACTERIAL SPOT DISEASE IN TOMATO | HEASLEY, MEGHAN CHRISTINE | 1626 | §103 | Final Rejection | — | Pending | Mar 06, 2024 |
| 18682048 | VIRTUAL BUILDING CONSTRUCTION INSPECTION FOR PERMITTING | EDMONDS, DONALD J | 3629 | §101 | Non-Final OA | — | Pending | Feb 07, 2024 |
| 18293521 | SYSTEMS AND METHODS FOR AUTOMATING THE CONSTRUCTION AND ORGANIZATION OF A TAXONOMY | BHUYAN, MOHAMMAD SOLAIMAN | 2168 | §101§103 | Final Rejection | 22d | Pending | Jan 30, 2024 |
| 18580480 | HYBRID ELECTROMECHANICAL TRANSFORMER | KLIMOWICZ, WILLIAM JOSEPH | — | §102§103 | Non-Final OA | — | Pending | Jan 18, 2024 |
| 18556967 | SEMI-CLOSED CYCLE AERO ENGINE WITH CONTRAIL SUPPRESSION | MEILLER, SEAN V | 3741 | §103 | Final Rejection | 49d | Pending | Oct 24, 2023 |
| 18555956 | ENZYMATICALLY-CLEAVABLE GLYCIDYL METHACRYLATE HYALURONIC ACID | ROBINSON, HOPE A | 1652 | §103 | Non-Final OA | — | Pending | Oct 18, 2023 |
| 18267184 | HIGH DIMENSIONAL AND ULTRAHIGH DIMENSIONAL DATA ANALYSIS WITH KERNEL NEURAL NETWORKS | COVINGTON, AMANDA R | 3686 | §101§103 | Non-Final OA | — | Pending | Jun 14, 2023 |
| 18204602 | SELF-ASSEMBLED THIN CARBON NANOTUBE FILMS USING AMPHIPHILIC PENDANT POLYMER DISPERSANTS | NGUYEN, HAIDUNG D | 1761 | §102§103 | Final Rejection | — | Pending | Jun 01, 2023 |
| 18026300 | COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME | SCHLIENTZ, LEAH H | 1618 | §103 | Final Rejection | — | Pending | Mar 14, 2023 |
| 18013954 | EXERGY-BASED LIFE CYCLE ASSESSMENT OF BUILDINGS | YESILDAG, MEHMET | 3624 | §101§102 | Final Rejection | 5d overdue | Pending | Dec 30, 2022 |
| 18013359 | IN-SITU SERVO-HYDRAULIC BIO-MANIPULATOR | HUANG, MICKEY NMN | 1758 | §103 | Final Rejection | — | Pending | Dec 28, 2022 |
| 17925776 | BENZOYLHYDRAZIDE-DERIVED HDAC DEGRADERS AS THERAPEUTICS FOR TREATING CANCER AND OTHER HUMAN DISEASES | SCHMIDT, IZABELA MARIA | 1621 | §103DP | Final Rejection | — | Pending | Nov 16, 2022 |
| 17912690 | GENE THERAPY FOR COCKAYNE SYNDROME | SINGH, ANOOP KUMAR | 1632 | §102§103§112 | Final Rejection | — | Pending | Sep 19, 2022 |
| 17906508 | DEUTERIUM MAGNETIC RESONANCE IMAGING | WESTERBERG, NISSA M | 1618 | §103§112 | Non-Final OA | — | Pending | Sep 16, 2022 |
| 17802686 | COMPOSITIONS, METHODS, KITS, AND SYSTEMS RELATING TO CHARGE-NEUTRAL MICROGELS FOR 3D CELL CULTURE AND PRINTING | KASAYAN, KATRIEL BARCELLANO | 1634 | §103 | Non-Final OA | — | Pending | Aug 26, 2022 |
| 17775206 | CRISPR COMPLEX-BASED DETECTION SYSTEM AND METHOD | SALVOZA, M FRANCO G | 1672 | §103§112Other | Non-Final OA | — | Pending | May 06, 2022 |
| 17727519 | Method of Treating Colorectal Cancers Using a PKC Inhibitor | LEE, WILLIAM Y | 1623 | §103 | Final Rejection | 29d | Pending | Apr 22, 2022 |
| 17565972 | CELLULAR MICRO-MASONRY SYSTEM | NGUYEN, HENRY H | 1758 | §103 | Final Rejection | 18d overdue | Pending | Dec 30, 2021 |
| 17286151 | MAGNETICALLY RESPONSIVE COMPOSITE MICROPARTICLES FOR TRIGGERED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS | HOERNER, PAUL ELLSWORTH | 1611 | §103 | Non-Final OA | — | Pending | Apr 16, 2021 |
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