Last updated: July 17, 2026

Application No. 18/515,196

TGF-BETA INHIBITION FOR IMMUNODEFICIENCY VIRUS REACTIVATION FROM LATENCY, ENHANCEMENT OF IMMUNODEFICIENCY VIRUS-SPECIFIC RESPONSES AND IMMUNODEFICIENCY VIRUS CURE

Non-Final OA

Filed

Nov 20, 2023

Priority

Nov 18, 2022 — provisional 63/384,368

Examiner

KINSEY WHITE, NICOLE ERIN

Art Unit

1672

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Northwestern University

OA Round

1 (Non-Final)

This examiner grants 58% of cases after interview

— +16.3% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 866 resolved cases, 2023–2026

Examiner Intelligence

KINSEY WHITE, NICOLE ERIN View full profile →

Grants 58% of resolved cases

Career Allowance Rate

501 granted / 866 resolved

-2.1% vs TC avg

Strong +16% interview lift

Without

With

+16.3%

Interview Lift

resolved cases with interview

Typical timeline

3y 2m

Avg Prosecution

39 currently pending

Career history

899

Total Applications

across all art units

Statute-Specific Performance

§101

0.9%

-39.1% vs TC avg

§103

46.9%

+6.9% vs TC avg

§102

7.6%

-32.4% vs TC avg

§112

18.6%

-21.4% vs TC avg

Black line = Tech Center average estimate • Based on career data from 866 resolved cases

Prosecution Timeline

Nov 20, 2023

Application Filed

Jun 02, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

17/194,699

Patent 12674213

COMPOSITIONS AND METHODS FOR QUANTIFYING INTEGRATION OF RECOMBINANT VECTOR NUCLEIC ACID

5y 4m to grant Granted Jul 07, 2026

17/697,638

Patent 12669499

PROBES COMPRISING METAL NANOPARTICLES, MAGNETIC NANOPARTICLES AND TARGET-SPECIFIC FLUOROPHORES OR BINDING SITES

4y 3m to grant Granted Jun 30, 2026

18/004,494

Patent 12667613

Nucleoside-modified RNA for Inducing an Immune Response Against SARS-CoV-2

3y 5m to grant Granted Jun 30, 2026

17/405,419

Patent 12656335

METHOD FOR EVALUATING THE PRESENCE OF A VIRAL RESERVOIR, AND EVALUATING THE EFFICACY OF A DRUG AGAINST SAID RESERVOIR

4y 10m to grant Granted Jun 16, 2026

17/333,304

Patent 12648978

Modulation of AAV Vector Transgene Expression

5y 0m to grant Granted Jun 09, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2

Expected OA Rounds

58%

Grant Probability

74%

With Interview (+16.3%)

3y 2m (~7m remaining)

Median Time to Grant

Low

PTA Risk

Based on 866 resolved cases by this examiner. Grant probability derived from career allowance rate.