Prosecution Insights
Prosecution Insights
Technology areas: Biotechnology & Pharmaceuticals • Medical Devices & Mechanical Engineering
114 pending office actions • 64 art units • 106 examiners • 0 of 114 (0%) have an AI response strategy ready • 111 patents granted in the last 365 days
Northwestern University is managing 113 pending office actions in the Biotechnology & Pharmaceuticals technology area. These 113 actions are spread across 62 distinct art units, reflecting a very broad range of research and development. The university interacts with 105 distinct examiners, meaning the vast majority of pending actions are being reviewed by different individuals. This distribution across 62 art units and 105 examiners requires a prosecution strategy that can adapt to many different individual examiner preferences and art unit norms. The 113 pending office actions represent a substantial volume of intellectual property.
EBBINGHAUS, BRIANA NOEL is the busiest examiner, overseeing 2 pending office actions. This count of 2 actions is the highest concentration for any single examiner in the portfolio. The remaining actions are handled by the other distinct examiners. With 113 pending actions spread across 105 examiners, there is very little concentration of cases. Practitioners should focus on the 2 actions under EBBINGHAUS, BRIANA NOEL while also addressing the broader group of 105 distinct examiners. The 62 distinct art units provide the technical framework for these 113 pending office actions.
Based on the USPTO statutory response window for each pending office action. 34 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 34 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 1 (1%) |
| §101 + other | 22 (19%) |
| §103 only | 22 (19%) |
| §102 only | 5 (4%) |
| §112 only | 3 (3%) |
| Double-patenting only | 2 (2%) |
| Double-patenting + other | 8 (7%) |
| Multi-statute (no §101) | 51 (45%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| EBBINGHAUS, BRIANA NOEL | 2 | 61.6% | +63.5% |
| ZHU, JIANJIAN | 2 | 58.8% | +82.4% |
| SKROBARCZYK III, ROBERT ANTHONY | 2 | 16.7% | +16.3% |
| HADDAD, MOUSSA MAHER | 2 | 27.3% | +33.9% |
| SALMON, KATHERINE D | 2 | 42.8% | +37.9% |
| EIX, EMILY FAY | 2 | 45.5% | +78.3% |
| SHIN, DANA H | 2 | 27.0% | +27.0% |
| BUTTICE, AUDREY L | 2 | 47.9% | +25.9% |
| BRUTUS, JOEL F | 1 | 72.8% | +17.7% |
| NGUYEN, KATHLEEN V | 1 | 67.3% | +25.7% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18780061 | MACHINE LEARNING-BASED RISK-CLASSIFICATION OF ENDOMERIAL CANCER | PATEL, SHERYL GOPAL | 139d overdue |
| 18245324 | CLASSIFICATION OF FUNCTIONAL LUMEN IMAGING PROBE DATA | HOEKSTRA, JEFFREY GERBEN | 70d overdue |
| 18572345 | MULTIPLEXED ANTIGEN-BASED DETECTION OF SARS-COV-2 AND OTHER DISEASES USING NANOMECHANICAL SENSORS | MCCORMACK, ERIN KATHLEEN | 67d overdue |
| 17784891 | METHOD AND COMPOSITION FOR ENHANCING THE IMMUNE RESPONSE | REDDIG, PETER J | 38d overdue |
| 17421677 | RAPID REVERSE TRANSCRIPTION QUANTITATIVE POLYMERASE CHAIN REACTION | GIAMMONA, FRANCESCA FILIPPA | 30d overdue |
| 18009384 | HYDRATION SENSOR FOR MONITORING AND DIAGNOSIS OF SKIN DISEASES IN ANY ENVIRONMENT AND APPLICATION OF SAME | PARK, EVELYN GRACE | 26d overdue |
| 19122087 | Systems and Methods to Identify Commercialization and Partnership Potential for Research Institutions | SCHNEIDER, JOSHUA D | 18d overdue |
| 18865562 | Anatomic Imaging Derived 4D Hemodynamics Using Deep Learning | JASANI, ASHISH SHIRISH | 16d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18249057 | USE OF REELIN FOR TREATING CARDIAC DISEASES | BUTTICE, AUDREY L | 16d overdue |
| 17287668 | APPARATUS AND METHOD FOR MEASURING PHYSIOLOGICAL PARAMETERS OF MAMMAL SUBJECT AND APPLICATIONS OF SAME | HADDAD, MOUSSA MAHER | 12d |
| 16951638 | METHOD OF USING CHECKPOINT KINASE INHIBITOR THERAPY TO MODULATE ANTI-TUMORAL RESPONSE AGAINST CANCER AND SENSITIZE GLIOMAS TO IMMUNOTHERAPY | BUTTICE, AUDREY L | 57d |
| 19311921 | METHOD AND SYSTEM FOR HIGHLY PARALLEL ULTRASONIC DETECTION USING MICRO-RING RESONATOR IN AN ARRAY FORMAT | BRUTUS, JOEL F | — |
| 19259714 | HUMAN SPINAL CORD INJURY ORGANOIDS | EBBINGHAUS, BRIANA NOEL | — |
| 19227080 | PROGRAMMABLE STREAMING ARCHITECTURE FOR LOW-ENERGY HUMAN-CENTRIC VISION APPLICATIONS | NGUYEN, KATHLEEN V | — |
| 18941862 | BIOACTIVE AND ANTIOXIDANT SUPRAMOLECULAR POLYMER HYDROGELS FOR NEURAL CELL CULTURE | ZHU, JIANJIAN | — |
| 18929526 | COST EFFECTIVE CULTURE MEDIA AND PROTOCOL FOR HUMAN INDUCED PLURIPOTENT STEM CELLS | ZHU, JIANJIAN | — |
| Art Unit | Apps |
|---|---|
| 3791 | 5 |
| 1652 | 4 |
| 3796 | 4 |
| 1635 | 4 |
| 3797 | 3 |
| 1626 | 3 |
| 3783 | 3 |
| 1682 | 3 |
| 1681 | 3 |
| 1632 | 2 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19311921 | METHOD AND SYSTEM FOR HIGHLY PARALLEL ULTRASONIC DETECTION USING MICRO-RING RESONATOR IN AN ARRAY FORMAT | BRUTUS, JOEL F | 3797 | §102§103 | Non-Final OA | — | Pending | Aug 27, 2025 |
| 19259714 | HUMAN SPINAL CORD INJURY ORGANOIDS | EBBINGHAUS, BRIANA NOEL | 1632 | §101§102§103§112DP | Non-Final OA | — | Pending | Jul 03, 2025 |
| 19227080 | PROGRAMMABLE STREAMING ARCHITECTURE FOR LOW-ENERGY HUMAN-CENTRIC VISION APPLICATIONS | NGUYEN, KATHLEEN V | 2486 | §103§112 | Non-Final OA | — | Pending | Jun 03, 2025 |
| 19215178 | INFRARED THERMOGRAPHY FOR INTRAOPERATIVE FUNCTIONAL MAPPING | POPESCU, GABRIEL VICTOR | 3797 | §101§102§103 | Non-Final OA | — | Pending | May 21, 2025 |
| 19129428 | Fluid-Structure Instability-Based Physiomarker | LY, TOMMY TAI | 3797 | §101 | Non-Final OA | — | Pending | May 13, 2025 |
| 19122087 | Systems and Methods to Identify Commercialization and Partnership Potential for Research Institutions | SCHNEIDER, JOSHUA D | 3626 | §101§103§112 | Final Rejection | 18d overdue | Pending | Apr 17, 2025 |
| 19111123 | TRANSVENUS REVERSIBLE ELECTROPORATION | WEBSTER, KARMEL JOHANNA | — | §102§103§112 | Non-Final OA | — | Pending | Mar 12, 2025 |
| 19053742 | Efficient Ray-Tracing Rendering Processor with Optimization for Mobile Devices and Support of Inverse Rendering | PATEL, SHIVANG I | — | §102§112 | Non-Final OA | — | Pending | Feb 14, 2025 |
| 18880219 | REACTIVE OXYGEN SPECIES RESPONSIVE CLEAVABLE HIERARCHIAL METALLIC SUPRANANOSTRUCTURES | SCHLEIS, DANIEL J | 1784 | §102§112 | Non-Final OA | — | Pending | Dec 30, 2024 |
| 18876553 | METHODS OF FORMING STABLE CONDUCTIVE SURFACES | CHEN, BRET P | 1718 | §103§112 | Non-Final OA | 20d | Pending | Dec 18, 2024 |
| 18865562 | Anatomic Imaging Derived 4D Hemodynamics Using Deep Learning | JASANI, ASHISH SHIRISH | 3798 | §102§103 | Final Rejection | 16d overdue | Pending | Nov 13, 2024 |
| 18941862 | BIOACTIVE AND ANTIOXIDANT SUPRAMOLECULAR POLYMER HYDROGELS FOR NEURAL CELL CULTURE | ZHU, JIANJIAN | 1631 | §103 | Non-Final OA | — | Pending | Nov 08, 2024 |
| 18929268 | METHODS AND SYSTEMS RELATING TO ARTIFICIAL INTELLIGENCE FOR EARLY RECOGNITION OF RARE SKIN DISEASES | BOYAR, NOAH WILLIAM | — | §101§103§112 | Non-Final OA | — | Pending | Oct 28, 2024 |
| 18929526 | COST EFFECTIVE CULTURE MEDIA AND PROTOCOL FOR HUMAN INDUCED PLURIPOTENT STEM CELLS | ZHU, JIANJIAN | — | §102§103§112DP | Non-Final OA | — | Pending | Oct 28, 2024 |
| 18914929 | KERNEL-BASED ERGODIC SEARCH | KARWAN, SIHAR A | 3658 | §103 | Final Rejection | 84d | Pending | Oct 14, 2024 |
| 18901448 | METHOD AND SYSTEM FOR FUNCTIONAL AND STRUCTURAL REMODELING PROGRESSION IN ATRIAL FIBRILLATION | SKROBARCZYK III, ROBERT ANTHONY | — | §101§103§112 | Non-Final OA | — | Pending | Sep 30, 2024 |
| 18886300 | PLATFORM OF COMPOSABLE MAMMALIAN ELEMENTS OF TRANSCRIPTION (COMET) | FRONDA, CHRISTIAN L | 1652 | §103§112Other | Non-Final OA | — | Pending | Sep 16, 2024 |
| 18842004 | (3S,4R)-3-AMINO-4-(DIFLUOROMETHYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID AND RELATED COMPOUNDS AS SELECTIVE INACTIVATORS OF ORNITHINE AMINOTRANSFERASE | RAMACHANDRAN, UMAMAHESWARI | — | §102§103DP | Non-Final OA | — | Pending | Aug 27, 2024 |
| 18792715 | Synthesis of MEK7 Inhibitors and methods of Use Thereof | OH, TAYLOR V | — | §102§112 | Non-Final OA | — | Pending | Aug 02, 2024 |
| 18779742 | METHOD AND SYSTEM TO PREDICT RADIOFREQUENCY HEATING OF MEDICAL IMPLANTS | SILVA-AVINA, EMMANUEL | 2673 | §101§103 | Non-Final OA | — | Pending | Jul 22, 2024 |
| 18780061 | MACHINE LEARNING-BASED RISK-CLASSIFICATION OF ENDOMERIAL CANCER | PATEL, SHERYL GOPAL | 3685 | §101§103 | Final Rejection | 139d overdue | Pending | Jul 22, 2024 |
| 18777366 | Annuloplasty Ring For Receiving A Replacement Valve | MATHEW, SEEMA | — | §103Other | Non-Final OA | — | Pending | Jul 18, 2024 |
| 18775012 | ENGINEERED PROBIOTICS FOR DETECTION OF GASTROINTESTINAL DISEASE IN HUMANS | DAVIS, RUTH A | — | §102Other | Non-Final OA | — | Pending | Jul 17, 2024 |
| 18773685 | METHOD TO EVALUATE AND FACT-CHECK AN AI LARGE LANGUAGE MODEL CHAT RESPONSE USING DOMAIN- SPECIFIC AND DOMAIN-AGNOSTIC GUIDANCE FOR PERSONALIZED MEDICAL PROVIDER-PATIENT CONSULT | SAINT CYR, LEONARD | — | §103 | Non-Final OA | — | Pending | Jul 16, 2024 |
| 18725885 | METHODS AND DEVICES FOR CONTINUOUS ORGAN AND ORGAN ALLOGRAFT MONITORING | KERN, ASHLEIGH LAUREN | 3796 | §103 | Non-Final OA | — | Pending | Jul 01, 2024 |
| 18737061 | TISSUE EXPANDER WITH DRUG DELIVERY CAPABILITY | THOMAS, NATALIE NICOLE | — | §102§103 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18737515 | Systems and Methods for Latent Variable Modeling of Multiscale Neural Signals for Brain-Computer Interfaces | PHAKOUSONH, DARAVANH | — | §101§102§112 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18737007 | COMPUTE-IN-MEMORY PROCESSOR SUPPORTING BOTH GENERAL-PURPOSE CPU AND DEEP LEARNING | PHAM, LY D | 2827 | §112 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18735506 | FORMULATIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF TUMOR METASTASIS AND TUMORIGENESIS | SHIM, DAVID M. | 1626 | §103Other | Non-Final OA | — | Pending | Jun 06, 2024 |
| 18735858 | HUMAN SPINAL CORD INJURY ORGANOIDS | EBBINGHAUS, BRIANA NOEL | 1632 | §102§103§112 | Non-Final OA | — | Pending | Jun 06, 2024 |
| 18648764 | ELECTRICAL MODULATION FOR THE TREATMENT OF BRAIN TUMORS | HADDAD, MOUSSA MAHER | 3796 | §102§103§112 | Non-Final OA | — | Pending | Apr 29, 2024 |
| 18640956 | CONDUCTIVE ELASTOMER FOR BLADDER REGENERATION | WEBB, WALTER E | 1612 | §102§103 | Non-Final OA | — | Pending | Apr 19, 2024 |
| 18613535 | CONDUCTIVE NANOMATERIALS AND COMPOSITES THEREOF | NGUYEN, HAIDUNG D | 1761 | §102§112 | Non-Final OA | — | Pending | Mar 22, 2024 |
| 18691863 | LIPIODOL FORMULATION FOR TRANSARTERIAL CHEMOIMMUNOEMBOLIZATION | ARMSTRONG, SUSANNAH SIPPLE | 1616 | §102§103§112 | Final Rejection | — | Pending | Mar 13, 2024 |
| 18597748 | SYSTEM AND METHOD FOR DETECTING AN EMOTIONAL STATE | ABOUELELA, MAY A | 3791 | §102§103§112 | Non-Final OA | — | Pending | Mar 06, 2024 |
| 18595057 | DIAGNOSIS OF ACUTE AND CHRONIC LUNG DISEASES BY QUANTIFYING SPINK1 LEVEL | SALMON, KATHERINE D | — | §102§103§112Other | Non-Final OA | — | Pending | Mar 04, 2024 |
| 18583685 | CATALASE MIMETIC PEPTIDES | SHELTON, SYNPHANE LA'SHAWN | 1652 | §102§103§112 | Final Rejection | — | Pending | Feb 21, 2024 |
| 18420277 | HIGH-EFFICIENCY GOLD RECOVERY BY ADDITIVE-INDUCED SUPRAMOLECULAR POLYMERIZATION OF CYCLODEXTRIN | CRAIGO, BAHAR ALAWI | 1734 | §112 | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18418897 | LIPOTEICHOIC ACID FROM STAPHYLOCOCCUS EPIDERMIDIS AND ITS USE TO MODULATE NEURONAL ACTIVITY VIA PD-1 INHIBITORY SIGNALLING IN NEURONS | OGUNBIYI, OLUWATOSIN A | 1645 | §102§112 | Non-Final OA | — | Pending | Jan 22, 2024 |
| 18412362 | METHODS AND COMPOSITIONS FOR TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION | DEKARSKE, MADELINE MCGUIRE | 1622 | §102§103 | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18404041 | DEVICES AND METHODS FOR LIGHT DELIVERY | SKROBARCZYK III, ROBERT ANTHONY | 3783 | §102§103§112Other | Non-Final OA | — | Pending | Jan 04, 2024 |
| 18400950 | METHOD OF ELECTRODEPOSITION IN SEAWATER FOR THE GROWTH OF CONSTRUCTION MATERIALS | CONTRERAS, CIEL P | — | §103§112 | Non-Final OA | — | Pending | Dec 29, 2023 |
| 18572345 | MULTIPLEXED ANTIGEN-BASED DETECTION OF SARS-COV-2 AND OTHER DISEASES USING NANOMECHANICAL SENSORS | MCCORMACK, ERIN KATHLEEN | 3791 | §102§103§112 | Final Rejection | 67d overdue | Pending | Dec 20, 2023 |
| 18572447 | INDOCARBOCYANINE LIPID DERIVATIVES FOR IN VIVO CARGO DELIVERY | MCANANY, JOHN D | 1625 | §102§103§112 | Final Rejection | — | Pending | Dec 20, 2023 |
| 18544247 | GENE THERAPY TREATMENT OF ATRIAL FIBRILLATION | LANDSMAN, ROBERT S | — | §103DP | Non-Final OA | — | Pending | Dec 18, 2023 |
| 18569070 | Systems and Methods for Prediction of Hematoma Expansion Using Automated Deep Learning Image Analysis | DICKERSON, CHAD S | 2683 | §103 | Final Rejection | — | Pending | Dec 11, 2023 |
| 18531821 | METHODS FOR SINGLE CELL NANOPORE SEQUENCING TECHNOLOGY AND DATA ANALYSIS | SMITH, JENNIFER JOY | — | §101§102§103 | Non-Final OA | — | Pending | Dec 07, 2023 |
| 18517238 | HALIDE PEROVSKITE OPTICAL STORAGE AND MEMORY ARRAYS | TOBERGTE, NICHOLAS J | 2824 | §103 | Non-Final OA | — | Pending | Nov 22, 2023 |
| 18563509 | SELECTIVE SEPARATION OF HEXACHLOROPLATINATE(IV) DIANIONS BASED ON EXO-BINDING WITH CUCURBIT[6]URIL | CUTLIFF, YATE KAI RENE | — | §103§112 | Non-Final OA | — | Pending | Nov 22, 2023 |
| 18559244 | METHODS FOR DIAGNOSIS AND TREATMENT OF CHRONIC PROSTATITIS AND/OR CHRONIC PELVIC PAIN SYNDROME | EIX, EMILY FAY | 1653 | §101§102 | Non-Final OA | — | Pending | Nov 06, 2023 |
| 18288473 | MELANIN MATERIALS FOR TISSUE REPAIR | ANDERSON, REBECCA L | 1626 | §102 | Non-Final OA | — | Pending | Oct 26, 2023 |
| 18556311 | 3D-PRINTING OF STRONG LIVING SCAFFOLDS | KWON, JOHN SEUNGJAI | 3783 | §103 | Non-Final OA | — | Pending | Oct 19, 2023 |
| 18286619 | HIERARCHICAL DEEP LEARNING NEURAL NETWORKS-ARTIFICIAL INTELLIGENCE: AN AI PLATFORM FOR SCIENTIFIC AND MATERIALS SYSTEMS INNOVATION | KIM, DAVID | 3625 | §101§102§103§112 | Non-Final OA | — | Pending | Oct 12, 2023 |
| 18283699 | TARGETING MULTIPLE T CELL TYPES USING SPHERICAL NUCLEIC ACID VACCINE ARCHITECTURE | ARIETI, RUTH SOPHIA | 1635 | §102§103§112DP | Non-Final OA | — | Pending | Sep 22, 2023 |
| 18283710 | CRISPR-MEDIATED CLEAVAGE OF OLIGONUCLEOTIDE-DETECTABLE MARKER CONJUGATES FOR DETECTION OF TARGET ANALYTES | GUSSOW, ANNE | 1683 | §103§112 | Non-Final OA | — | Pending | Sep 22, 2023 |
| 18281648 | MULTI-LAYER BOROPHENE AND METHOD OF SYNTHESIZING SAME | ZHANG, HAI Y | 1732 | §102§112Other | Non-Final OA | — | Pending | Sep 12, 2023 |
| 18240201 | DIAGNOSIS AND TREATMENT OF PRIMARY GRAFT DYSFUNCTION FOLLOWING LUNG TRANSPLANT | BUCCINI, MICHELLE CALLAHAN | 1675 | §102§103 | Final Rejection | — | Pending | Aug 30, 2023 |
| 18548175 | CELL-FREE BIOSENSORS WITH DNA STRAND DISPLACEMENT CIRCUITS | SALMON, KATHERINE D | 1682 | §102§103§112DP | Non-Final OA | — | Pending | Aug 28, 2023 |
| 18279034 | STRATEGIES TO DEVELOP GENOME EDITING SPHERICAL NUCLEIC ACIDS (SNAS) | PAULUS, ERIN VIRGINIA | 1631 | §103DP | Non-Final OA | — | Pending | Aug 25, 2023 |
| 18274019 | FABRICATION OF PIXELATED RADIATION DETECTORS VIA LASER CUTTING | KERR, ELIZABETH M | 3761 | §103§112 | Non-Final OA | — | Pending | Jul 25, 2023 |
| 18225400 | SPHERICAL NUCLEIC ACIDS WITH DENDRITIC LIGANDS | SHIN, DANA H | 1635 | §103 | Final Rejection | — | Pending | Jul 24, 2023 |
| 18271782 | LIPID NANOPARTICLE SPHERICAL NUCLEIC ACIDS | GIBBS, TERRA C | 1635 | §103 | Non-Final OA | — | Pending | Jul 11, 2023 |
| 18270903 | BOROPHANE POLYMORPHS AND SYNTHESIS METHODS OF SAME | NGUYEN, CAM N | 1736 | §102§103 | Final Rejection | — | Pending | Jul 05, 2023 |
| 18215701 | Methods and Materials for Matching Chemistry of Individuals and Human Melanin | JARRETT, LORE RAMILLANO | 1797 | §101§102§112 | Final Rejection | 16d overdue | Pending | Jun 28, 2023 |
| 18334135 | TRANS-INTERFACIAL MAGNETIC SEPARATION | MARCSISIN, ELLEN JEAN | 1677 | §102§103 | Non-Final OA | 14d | Pending | Jun 13, 2023 |
| 18257261 | PI3K INHIBITORS FOR PROTECTION AGAINST GLUCOCORTICOID-INDUCED ATROPHY | MAHLUM, JONATHAN DAVIS | 1625 | §102§103§112 | Non-Final OA | — | Pending | Jun 13, 2023 |
| 18205826 | Systems and Methods for Enabling Situational Awareness for Events Via Data Visualization | OCHOA, JUAN CARLOS | — | §103§112 | Non-Final OA | — | Pending | Jun 05, 2023 |
| 18328967 | Portable Closed System for Culturing Cells Using Small Volumes of Capillary Blood | MARCHESCHI, MICHAEL A | 1796 | §102§103§112 | Non-Final OA | — | Pending | Jun 05, 2023 |
| 18327725 | ELECTRICAL WRITE/READ OF HIGH-INFORMATION-DENSITY MAGNETIC THIN FILM | SMET, UYEN TRAN | 2824 | §103 | Final Rejection | 15d overdue | Pending | Jun 01, 2023 |
| 18200932 | IN VIVO DETECTION OF SURGICAL MATERIALS | RAYMOND, LINNAE ELIZABETH | 3781 | §103§112 | Final Rejection | 23d | Pending | May 23, 2023 |
| 18035876 | ION-BASED METHODS FOR STABILIZING AND IMPROVING POROUS METAL-ORGANIC FRAMEWORK (MOF) MATERIALS FOR WATER HARVESTING FROM AIR AND RELATED APPLICATIONS | HOU, FRANK S | 1692 | §102 | Non-Final OA | — | Pending | May 08, 2023 |
| 18251604 | A CELL-FREE BIO-MANUFACTURING PLATFORM FOR PRODUCTION OF FATTY ACIDS AND CANNABINOIDS | RAMIREZ, DELIA M | 1652 | §102§112 | Non-Final OA | — | Pending | May 03, 2023 |
| 18251596 | METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAs CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE | GREENE, CAROLYN LEE | 1681 | §103 | Non-Final OA | — | Pending | May 03, 2023 |
| 18250140 | SYSTEMS AND METHODS FOR QUANTIFYING PATIENT IMPROVEMENT THROUGH ARTIFICIAL INTELLIGENCE | STRIEGEL, THEODORE CHARLES | — | §101§103§112 | Non-Final OA | — | Pending | Apr 21, 2023 |
| 18249057 | USE OF REELIN FOR TREATING CARDIAC DISEASES | BUTTICE, AUDREY L | 1647 | §103§112 | Final Rejection | 16d overdue | Pending | Apr 13, 2023 |
| 18029432 | COMPOSITES WITH SURFACE REFINING AND CONFORMAL GRAPHENE COATING, ELECTRODES, AND FABRICATING METHODS OF SAME | WEST, ROBERT GENE | 1721 | §103§112 | Non-Final OA | 46d | Pending | Mar 30, 2023 |
| 18028934 | INTEGRATION OF ELECTROPHYSIOLOGY MAPPING SYSTEMS WITH ELECTROPORATION SYNCHRONIZED WITH PACING | GEDEON, BRIAN T | 3796 | §103 | Non-Final OA | 45d overdue | Pending | Mar 28, 2023 |
| 18245324 | CLASSIFICATION OF FUNCTIONAL LUMEN IMAGING PROBE DATA | HOEKSTRA, JEFFREY GERBEN | 3791 | §101§102§112 | Final Rejection | 70d overdue | Pending | Mar 14, 2023 |
| 18021687 | B-CELL BASED IMMUNOTHERAPY FOR THE TREATMENT OF GLIOBLASTOMA AND OTHER CANCERS | JUEDES, AMY E | 1644 | §103 | Final Rejection | 7d | Pending | Feb 16, 2023 |
| 18021429 | GRAPHENE-FUNCTIONALIZED COMPOSITES FOR BATTERY ANODES, FORMING METHODS AND APPLICATIONS OF SAME | YOON, KEVIN E | 1735 | §102 | Non-Final OA | 17d overdue | Pending | Feb 15, 2023 |
| 18017372 | GRAPHENE METAL ORGANIC FRAMEWORK COMPOSITE ELECTRODES FOR LITHIUM-SULFUR BATTERIES | BULLOCK, IN SUK C | 1723 | §103§112 | Non-Final OA | — | Pending | Jan 20, 2023 |
| 18006120 | SYSTEMS AND METHODS FOR RAPIDLY SCREENING FOR SIGNS AND SYMPTOMS OF DISORDERS | EDOUARD, JONATHAN CHRISTOPHER | 3683 | §101§103 | Final Rejection | — | Pending | Jan 19, 2023 |
| 18005826 | ENGINEERED N-GLYCOSYLTRANSFERASES WITH ALTERED SPECIFICITIES | EIX, EMILY FAY | 1653 | §103§112 | Final Rejection | — | Pending | Jan 17, 2023 |
| 18153872 | TANDEM REPEAT PROTEIN SEQUENCES IN PROTEIN-LIKE POLYMERS AND USES THEREOF | LIEB, JEANETTE M | 1654 | §102 | Non-Final OA | — | Pending | Jan 12, 2023 |
| 18004104 | HUMAN RECOMBINANT ACE2-FC MUTANTS THAT DECOUPLE ANTI-SARS-COV-2 ACTIVITY FROM CARDIOVASCULAR EFFECTS | NIEBAUER, RONALD T | 1658 | §103§112 | Final Rejection | — | Pending | Jan 03, 2023 |
| 18009384 | HYDRATION SENSOR FOR MONITORING AND DIAGNOSIS OF SKIN DISEASES IN ANY ENVIRONMENT AND APPLICATION OF SAME | PARK, EVELYN GRACE | 3791 | §103§112 | Final Rejection | 26d overdue | Pending | Dec 09, 2022 |
| 18048673 | A SYNTHENTIC POLY-TRANSTHYRETIN AFFINITY TRAP FOR DETECTING AMYLOIDOGENIC TRANSTHYRETIN FORMS IN PLASMA SAMPLES OFTRANTHYRETIN AMYLOIDOSIS PATIENTS | DUNN, MCKENZIE A | 1678 | §103 | Final Rejection | — | Pending | Oct 21, 2022 |
| 17995825 | CHEMICALLY TUNABLE OPTICALLY ADDRESSABLE MOLECULR-SPIN QUBIT AND ASSOCIATED METHODS | PATERSON, BRIGITTE A | 2812 | §102§112 | Non-Final OA | — | Pending | Oct 07, 2022 |
| 17936208 | Carbohydrate-Modified Particles and Particulate Formulations for Modulating an Immune Response | BASQUILL, SEAN M | 1614 | §103 | Final Rejection | 72d overdue | Pending | Sep 28, 2022 |
| 17908809 | FIT-FLARES FOR DETECTION OF INTRACELLULAR ANALYTES IN LIVE CELLS | DAUNER, JOSEPH G | 1682 | §102§103DP | Non-Final OA | 50d overdue | Pending | Sep 01, 2022 |
| 17814211 | ADOPTIVE CELL THERAPY USING SPHERICAL NUCLEIC ACIDS (SNAS) | CHONG, KIMBERLY | 1636 | §103§112 | Non-Final OA | — | Pending | Jul 21, 2022 |
| 17784891 | METHOD AND COMPOSITION FOR ENHANCING THE IMMUNE RESPONSE | REDDIG, PETER J | 1646 | §103§112 | Non-Final OA | 38d overdue | Pending | Jun 13, 2022 |
| 17778340 | FLUID MECHANICS-BASED ANALYSIS TOOL TO ESTIMATE FLOW DATA FROM PLANIMETRY CATHETER DATA | ROBERTS, ANNA L | 3791 | §101§103 | Non-Final OA | 27d | Pending | May 19, 2022 |
| 17775187 | MACHINE LEARNING TOOLS AND A PROCESS TO DISCOVER NEW NATURAL PRODUCTS BY LINKING GENOMES AND METABOLOMES IN FUNGI | SANFORD, DIANA PATRICIA | 1687 | §101§103§112 | Final Rejection | — | Pending | May 06, 2022 |
| 17773519 | GOLD NANOPARTICLES/NANOSHELLS IMMUNE CONJUGATES FOR ENHANCED IMMUNOTHERAPY AND PHOTOTHERMAL THERAPY FOR HEMATOLOGIC MALIGNANCIES | BLUMEL, BENJAMIN P | 1671 | §102§103 | Final Rejection | — | Pending | Apr 29, 2022 |
| 17772169 | MOLECULAR COMPUTING METHODS AND SYSTEMS FOR SOLVING COMPUTATIONAL PROBLEMS | NEGIN, RUSSELL SCOTT | 1686 | §101§103 | Non-Final OA | — | Pending | Apr 27, 2022 |
| 17760990 | HIGH DENSITY LIPOPROTEIN-LIKE NANOPARTICLES AS INDUCERS OF FERROPTOSIS IN CANCER | FAY, ZOHREH ALEMZADEH | 1617 | §102§103 | Non-Final OA | 27d | Pending | Mar 16, 2022 |
| 17641525 | MULTIPLEXED WEARABLE SENSORS FOR PREGNANCY MONITORING AND APPLICATIONS OF SAME | HOLTZCLAW, MICHAEL T. | 3700 | §101§103§112 | Non-Final OA | — | Pending | Mar 09, 2022 |
| 17637410 | BLOOD GENE BIOMARKERS TO DIAGNOSE AND PREDICT ACUTE REJECTION IN LIVER TRANSPLANT RECIPIENTS | MYERS, CARLA J | 1682 | §101§102§103§112 | Non-Final OA | 2d overdue | Pending | Feb 22, 2022 |
| 17625023 | METHODS OF USING MODIFIED CYTOTOXINS TO TREAT CANCER | KUCKLA, ANNA GRACE | 1626 | §103 | Non-Final OA | 12d | Pending | Jan 05, 2022 |
| 17621088 | FORCED INTERCALATION (FIT)-APTAMERS: PROBES BASED ON FORCED INTERCALATION | CHUNDURU, SURYAPRABHA | 1681 | DP | Final Rejection | 38d overdue | Pending | Dec 20, 2021 |
| 17445285 | ENHANCING SUBCUTANEOUS INJECTION AND TARGET TISSUE ACCUMULATION OF NANOPARTICLES VIA CO-ADMINISTRATION WITH MACROPINOCYTOSIS INHIBITORY NANOPARTICLES (MINP) | WESTERBERG, NISSA M | 1618 | §103 | Final Rejection | 28d overdue | Pending | Aug 17, 2021 |
| 17392847 | DEVICES AND METHODS FOR TREATING A STRICTURE ALONG THE BILIARY AND/OR PANCREATIC TRACT | LALONDE, ALEXANDRA ELIZABETH | 3783 | §103§112 | Final Rejection | — | Pending | Aug 03, 2021 |
| 17421677 | RAPID REVERSE TRANSCRIPTION QUANTITATIVE POLYMERASE CHAIN REACTION | GIAMMONA, FRANCESCA FILIPPA | 1681 | §103§112 | Final Rejection | 30d overdue | Pending | Jul 08, 2021 |
| 17311108 | Protein Crystal Engineering Through DNA Hybridization Interactions | MOAZZAMI, NAGHMEH NINA | 1652 | §102§103 | Final Rejection | 79d | Pending | Jun 04, 2021 |
| 17287668 | APPARATUS AND METHOD FOR MEASURING PHYSIOLOGICAL PARAMETERS OF MAMMAL SUBJECT AND APPLICATIONS OF SAME | HADDAD, MOUSSA MAHER | 3796 | §103§112DP | Final Rejection | 12d | Pending | Apr 22, 2021 |
| 17273438 | DATA-DRIVEN REPRESENTATION AND CLUSTERING DISCRETIZATION METHOD AND SYSTEM FOR DESIGN OPTIMIZATION AND/OR PERFORMANCE PREDICTION OF MATERIAL SYSTEMS AND APPLICATIONS OF SAME | HANN, JAY B | 2186 | §101§103 | Non-Final OA | — | Pending | Mar 04, 2021 |
| 16951638 | METHOD OF USING CHECKPOINT KINASE INHIBITOR THERAPY TO MODULATE ANTI-TUMORAL RESPONSE AGAINST CANCER AND SENSITIZE GLIOMAS TO IMMUNOTHERAPY | BUTTICE, AUDREY L | 1647 | §103§112 | Final Rejection | 57d | Pending | Nov 18, 2020 |
| 17054441 | SELF-MANAGEABLE ABNORMAL SCAR TREATMENT WITH SPHERICAL NUCLEIC ACID (SNA) TECHNOLOGY | NGUYEN, JOHN P | 1619 | §103 | Non-Final OA | 70d | Pending | Nov 10, 2020 |
| 17076607 | SPHERICAL NUCLEIC ACIDS WITH DENDRITIC LIGANDS | SHIN, DANA H | 1635 | DP | Final Rejection | — | Pending | Oct 21, 2020 |
| 17074343 | SYSTEMS AND METHODS FOR UNTARGETED METABOLOMIC SCREENING | PLAYER, ROBERT AUSTIN | 1686 | §101§103 | Final Rejection | — | Pending | Oct 19, 2020 |
| 17046482 | ADDRESSING NANOMEDICINE COMPLEXITY THROUGH NOVEL HIGH-THROUGHPUT SCREENING AND MACHINE LEARNING | BEIL, RANDI LYNN | 1684 | §103 | Final Rejection | 69d | Pending | Oct 09, 2020 |
| 16773540 | MATERIALS AND METHODS FOR GENE DELIVERY IN THE HEART | CRAIG, KAILA ANGELIQUE | 1618 | §103 | Non-Final OA | 72d | Pending | Jan 27, 2020 |
| 16312973 | BIO-ELECTRIC NOSE | LEVIN, JOEL D | 1633 | §112 | Final Rejection | 49d overdue | Pending | Dec 21, 2018 |
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