Prosecution Insights
Last updated: August 14, 2026
Application No. 18/533,181

METHOD OF USING/APPLYING A KERATIN HYDROLYSIS PEPTIDE SOLUTION TO ENAHNCE THE FLAVOR OF TEA LEAVES

Final Rejection §112
Filed
Dec 08, 2023
Priority
Sep 22, 2023 — TW 112136374
Examiner
KIEFER, DALTON EDWARD
Art Unit
1652
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Ch Biotech R&D Co. Ltd.
OA Round
2 (Final)
Grant Probability
Favorable
3-4
OA Rounds

Examiner Intelligence

Grants only 0% of cases
0%
Career Allowance Rate
0 granted / 0 resolved
-60.0% vs TC avg
Minimal +0% lift
Without
With
+0.0%
Interview Lift
resolved cases with interview
Typical timeline
Avg Prosecution
27 currently pending
Career history
19
Total Applications
across all art units

Statute-Specific Performance

§103
27.2%
-12.8% vs TC avg
§102
24.7%
-15.3% vs TC avg
§112
35.8%
-4.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 0 resolved cases

Office Action

§112
DETAILED ACTION Status of the Application Claims 1-6 are pending. The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Receipt is acknowledged of Amendments, Remarks (including a Declaration) and a Terminal Disclaimer filed on 05/22/2026. Terminal Disclaimer The terminal disclaimer filed on 05/22/2026 disclaiming the terminal portion of any patent granted on this application which would extend beyond the expiration date of pending reference Application Number 18/758140 (filed on 06/28/2024) has been reviewed and is accepted. The terminal disclaimer has been recorded. Priority Acknowledgment is made of applicant’s claim for foreign priority under 35 U.S.C. 119 (a)-(d) to Application No.TW112136374, filed on 09/22/2023; which papers have been made of record in the file. Specification (previous objection, withdrawn) The specification is objected for not complying with sequence rules. While Table 1 displays sequences, neither the drawings nor the Brief Description of the Drawings indicate the corresponding sequence identifiers. Applicant is required to insert the corresponding sequence identifiers in the Brief Description of the Drawings or amend the drawings to include the sequence identifiers in front of each sequence. See particularly 37 CFR 1.821(d). Appropriate correction is required. Response to Arguments Applicant’s arguments, page 2 of Remarks/Detailed Response to Office Action, filed on 05/22/2026, with respect to the sequence identifiers have been fully considered and are persuasive. The objection of 02/26/2026 has been withdrawn. 35 U.S.C. 112(a) or pre-AIA 35 U.S.C. 112, requires the specification to be written in “full, clear, concise, and exact terms.” The specification is replete with terms which are not clear, concise and exact. The specification should be revised carefully in order to comply with 35 U.S.C. 112(a) or pre-AIA 35 U.S.C. 112. Examples of some unclear, inexact or verbose terms used in the specification are: (previous objection, withdrawn) Paragraph [0013] Objected to in the recitation of “prior researches”. Research is an uncountable noun. To improve clarity, the term should be amended to “prior research”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0013] Objected to for not following SI conventions. A space should be between numbers and the percentage symbol. A space is needed between “nitrogen,1.6”. To improve clarity, the terms should be amended to “91 % keratin”, “15 % organic nitrogen”, “2 % organic sulfur” and “nitrogen, 1.6”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0017] Objected to for not following SI conventions. A space should be between a number and percentage symbol. In the recitation of “50%”, the term should be amended to “50 %”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0017] Objected to in the recitation of “embodiment of present invention”. To improve clarity, the term should be amended to “embodiment of the present invention”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0022] Objected in the recitation of “uses mixes”. To improve clarity, the term should be amended to remove “uses” and read “A second embodiment mixes”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0032] Objected in the recitation of “where the weight ratio whereby the weight ratio”. To improve clarity, the term should be amended to “whereby the weight ratio”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0033] Objected to for not following SI conventions. A space should be between a number and percentage symbol. In the recitation of “50%”, the term should be amended to “50 %”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0033] Objected to for not following SI conventions. A space should be between a number and degrees symbol. In the recitation of “185°C”, the term should be amended to “185 °C”. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0036] Objected to in the recitation of “sprayed to the tea leaves’ surface”. To improve clarity, the term should be amended to “sprayed on the tea leaves’ surface”. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0038] Objected to in the recitation of “solution of present invention”. To improve clarity, the term should be amended to “solution of the present invention”. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0038] Objected to for not following SI conventions. A space should be between a number and units. In the recitation of “66kg”, the term should be amended to “66 kg”. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0039] Objected to for not following SI conventions. A space should be between a number and percentage symbol. In the recitation of “50%”, the term should be amended to “50 %”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0039] Objected to for not following SI conventions. A space should be between a number and degrees symbol. In the recitation of “195°C”, the term should be amended to “195 °C”. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0043] Objected to in the recitation of “inventors of present”. To improve clarity, the term should be amended to “inventors of the present”. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0044] Objected to in the recitation of “CK” and “(CHK)”. To improve clarity the terms should be amended to match. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0047] Objected to for not following SI conventions. A space should be between a number and degrees symbol. In the recitation of “70°C”, the term should be amended to “70 °C”. Appropriate corrections are required. (previous objection, withdrawn) Paragraph [0047] Objected to for not following SI conventions. A space should be between a number and percentage symbol. In the recitation of “3%”, the term should be amended to “3 %”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0048] Objected in the recitation of “Fig.1B respectively”. To improve clarity, the term should be amended to “Fig.1B, respectively”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0049] Objected to for not following SI conventions. A space should be between a number and percentage symbol. In the recitation of “70%”, “10%” and “7.5%, the terms should be amended to “70 %”, “10 %” and “7.5 %”. Appropriate correction is required. (previous objection, withdrawn) Paragraph [0049] Objected to for not following SI conventions. A space should be between a number and degrees symbol. In the recitation of “70°C”, the term should be amended to “70 °C”. Appropriate corrections are required. Claim Objections Claims 1-6 are objected to because of the following informalities: (previous objection, withdrawn) Claim 1 is objected to in the recitation of “50%” and “185°C”. Following SI conventions, the terms should be amended to “50 %” and “185 °C. Appropriate corrections are required. (previous objection, withdrawn) Claim 1 is objected in the recitation of “using a keratin hydrolysis peptide (KHP) solution to a tea plant”. To improve clarity, the term should be amended to using a keratin hydrolysis peptide (KHP) solution on a tea plant”. Appropriate corrections are required. (previous objection, withdrawn) Claim 2 is objected to in the recitation of “claim1 where”. To improve clarity and be consistent with commonly used claim language, the term should be amended to “claim 1, wherein”. Appropriate corrections are required. (previous objection, withdrawn) Claim 2 is objected to in the recitation of “sprayed to the tea”. To improve clarity, the term should be amended to “sprayed on the tea”. Appropriate corrections are required. (previous objection, withdrawn) Claim 3 is objected to in the recitation of “claim1 where”. To improve clarity and be consistent with commonly used claim language, the term should be amended to “claim 1, wherein”. Appropriate corrections are required. (previous objection, withdrawn) Claim 4 is objected in the recitation of “using a keratin hydrolysis peptide (KHP) solution to a tea plant”. To improve clarity, the term should be amended to “using a keratin hydrolysis peptide (KHP) solution on a tea plant”. Appropriate corrections are required. (previous objection, withdrawn) Claim 4 is objected to in the recitation of “50%” and “195°C”. Following SI conventions, the terms should be amended to “50 %” and “195 °C. Appropriate corrections are required. (previous objection, withdrawn) Claim 5 is objected to in the recitation of “claim 4 where”. To improve clarity and be consistent with commonly used claim language, the term should be amended to “claim 4, wherein”. Appropriate corrections are required. (previous objection, withdrawn) Claim 5 is objected to in the recitation of “sprayed to the tea”. To improve clarity, the term should be amended to “sprayed on the tea”. Appropriate corrections are required. (previous objection, withdrawn) Claim 6 is objected to in the recitation of “claim 4 where”. To improve clarity and be consistent with commonly used claim language, the term should be amended to “claim 4, wherein”. Appropriate corrections are required. Response to Arguments Applicant’s arguments on page 2, filed on 05/22/2026 with respect to the claim objections of claims 1-8 have been fully considered and are persuasive. The objections of 02/10/2026 have been withdrawn. Claim Rejections - 35 USC § 112(b) The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claim 1-6 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. (previous rejection, withdrawn) Claims 1 and 4 (claims 2-3, 5-6 dependent thereon) are rejected as being indefinite in the recitation of “contain at least 253 peptides… where their molecular masses are between 500 and 4,000 Daltons” for the following reason. It is unclear if the molecular mass is for each peptide or the total number of peptides present in the solution. Correction is required. Response to Arguments Applicant's arguments, see page 2-3 and Declaration filed 05/22/2026, have been fully considered and are persuasive. The rejections of 02/26/2026 have been withdrawn. (previous rejection, withdrawn) Claims 1 and 4 (claims 2-3, 5-6 dependent thereon) are indefinite in the recitation of “concentration is in the range of 2.0 x 105 ~ 4.5 x 105 ppm” for the following reasons. As written, it is unclear as to which is the compound that should have the recited concentration of “2.0 x 105~ 4.5 x 105 ppm” in the peptide solution. Moreover, in view of the fact that claims 1 and 4 refer to a combination of “at least 253 peptides”, even if one assumes that the “2.0 x 105 ~ 4.5 x 105 ppm” concentration recited refers to peptides, it is unclear if the “2.0 x 105 ~ 4.5 x 105 ppm” refers solely to the 253 peptides or any peptide in the solution. Correction is required. Response to Arguments Applicant's arguments, see pages 3 and Declaration filed 05/22/2026, have been fully considered and are persuasive. The rejections of 02/26/2026 have been withdrawn. (previous rejection, withdrawn) Claims 1 and 4 (claims 2-3, 5-6 dependent thereon) are indefinite in the recitation of “Preparing the KHP solution by mixing 50 kg of feathers whose content is 50% water and 40 kg of water in a sealed container” for the following reasons. It is unclear whether the phrase “50% water” refers to the amount of water present in the sealed container in addition to the feathers or whether the phrase refers to the percentage of water present or retained by the feathers. The claims are silent with the respect to how the % is measured, e.g. by mass, by volume, etc. Correction is required. Response to Arguments Applicant's arguments, see pages 3-4 and Declaration filed 05/22/2026, have been fully considered and are persuasive. The rejections of 02/26/2026 have been withdrawn. (previous rejection, maintained) Claims 1 and 4 (claims 2-3, 5-6 dependent thereon) are rejected as being indefinite in the recitation of “at least 253 peptides as listed in the specification” for the following reasons. The term “as listed in the specification” can be interpreted as exemplary language (i.e., such as). Therefore, it is unclear if the 253 peptides are necessarily those in Table 1. In addition, as set forth in MPEP § 2173.05(s), where possible, claims are to be complete in themselves and incorporation by reference to a section of the specification such as a Figure or a Table is permitted only in exceptional circumstances where there is no practical way to define the invention. If the intended peptides have a sequence identifier provided in the sequence listing, it is suggested the claim be amended to refer to specific sequence identifiers associated with the desired peptides. For examination purposes, no patentable weight will be given to the term “using a mass spectrometer …molecular masses are between…Daltons…concentration range of 2.0 x 105 ~ 4.5 x 105 ppm”. Correction is required. Response to Arguments Applicant's arguments, see page 3, filed 05/22/2026, have been fully considered and are not persuasive. Applicant argues that the claimed element of “at least 253 peptides” is disclosed in the Specification (Table 1, as revised, no new matter is introduced). Applicant further argues that fully setting forth the peptides, which include the sequence identifier s, in the claims is impracticable and does not add to the clarity of the patent documents. However, “at least 253 peptides as listed in the specification” is indefinite as “at least” encompasses infinity, which is neither possible or envisioned and it is not specified in the claims where at in the specification these “at least 253 peptides” are and what they are. Conclusion No claims are allowed. THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to DALTON KIEFER, PhD whose telephone number is (571)272-1235. The examiner can normally be reached M-F 7:30-5 EST. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Robert Mondesi can be reached at (408)918-7584. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /DALTON EDWARD KIEFER/Examiner, Art Unit 1652 /ROBERT B MONDESI/Supervisory Patent Examiner, Art Unit 1652
Read full office action

Prosecution Timeline

Dec 08, 2023
Application Filed
Feb 26, 2026
Non-Final Rejection mailed — §112
May 22, 2026
Response after Non-Final Action
May 22, 2026
Response Filed
Jul 20, 2026
Final Rejection mailed — §112 (current)

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.
Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

3-4
Expected OA Rounds
Grant Probability
Moderate
PTA Risk
Based on 0 resolved cases by this examiner. Grant probability derived from career allowance rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month