Last updated: August 14, 2026

Application No. 18/746,428

FORMULATIONS OF T-TYPE CALCIUM CHANNEL MODULATORS AND METHODS OF USE THEREOF

Non-Final OA

Filed

Jun 18, 2024

Priority

Jul 11, 2019 — provisional 62/873,022 +5 more

Examiner

CHANDRAKUMAR, NIZAL S

Art Unit

1625

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Praxis Precision Medicines Inc.

OA Round

1 (Non-Final)

Interview Optional

— +18.3% interview lift. Interview already conducted in this application's prosecution history. This examiner has a 73% grant rate with +18.3% interview lift. Since an interview has already been tried, recommend written response with narrowed claims based on precedent claim evolution patterns.

Based on 1774 resolved cases, 2023–2026

Examiner Intelligence

CHANDRAKUMAR, NIZAL S View full profile →

Grants 73% — above average

Career Allowance Rate

1289 granted / 1774 resolved

+12.7% vs TC avg

Strong +18% interview lift

Without

With

+18.3%

Interview Lift

resolved cases with interview

Typical timeline

2y 3m

Avg Prosecution

92 currently pending

Career history

1862

Total Applications

across all art units

Statute-Specific Performance

§101

2.2%

-37.8% vs TC avg

§103

29.1%

-10.9% vs TC avg

§102

11.1%

-28.9% vs TC avg

§112

36.7%

-3.3% vs TC avg

Black line = Tech Center average estimate • Based on career data from 1774 resolved cases

Prosecution Timeline

Jun 18, 2024

Application Filed

Jul 15, 2026

Examiner Interview (Telephonic)

Jul 15, 2026

Examiner Interview Summary

Jul 23, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/274,905

Patent 12698292

TOXIN MOLECULE SUITABLE FOR ANTIBODY-DRUG CONJUGATE

3y 0m to grant Granted Aug 04, 2026

18/383,450

Patent 12698263

PROCESS FOR PREPARING 3-AMINO-1-BUTANOL AND RELATED COMPOUNDS

2y 9m to grant Granted Aug 04, 2026

17/203,802

Patent 12693297

COUMARIN-BASED CROSSLINKING REAGENTS

5y 4m to grant Granted Jul 28, 2026

18/019,598

Patent 12685738

INOTODIOL AS AGONIST OF LIVER X RECEPTORS, AND USE THEREOF

3y 5m to grant Granted Jul 21, 2026

18/222,153

Patent 12678466

Method to Improve Therapeutic Properties of Stem Cells

3y 0m to grant Granted Jul 14, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2

Expected OA Rounds

73%

Grant Probability

91%

With Interview (+18.3%)

2y 3m (~1m remaining)

Median Time to Grant

Low

PTA Risk

Based on 1774 resolved cases by this examiner. Grant probability derived from career allowance rate.