Prosecution Insights
Last updated: October 27, 2026

Illumina Inc.

Technology area: Biotechnology & Pharmaceuticals

124 pending office actions • 31 art units • 86 examiners • 0 of 124 (0%) have an AI response strategy ready • 129 patents granted in the last 365 days

Analysis

Illumina Inc. has 123 pending office actions in Biotechnology & Pharmaceuticals. The matters involve 86 examiners across 30 art units, creating a broad prosecution network that spans many examination assignments and technical groupings.

POHNERT, STEVEN C is the busiest examiner, with 7 pending matters. That concentration is material within the profile, but the wider distribution means counsel should combine examiner-specific analysis with art-unit coordination, standardized issue tracking, and disciplined response management.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

124
Total Pending OAs
80
Non-Final OAs
42
Final Rejections
2
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 23 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

9
Overdue
0
Due this week
7
Due this month
5
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 23 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (9)Due ≤ 30 days (7)Due ≤ 60 days (5)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

73
Hard (59%)
42
Medium (34%)
8
Easy (6%)
1
Unknown (1%)

Rejection Statute Mix

BucketCases
§101 only5 (4%)
§101 + other33 (27%)
§103 only28 (23%)
§102 only7 (6%)
§112 only7 (6%)
Double-patenting only1 (1%)
Double-patenting + other7 (6%)
Multi-statute (no §101)35 (28%)
No statute on record1 (1%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

108
Life Sciences
87% of docket
4
Information Tech
3% of docket
1
Communications
1% of docket
4
Semiconductors
3% of docket
2
Mechanical / Eng
2% of docket
5
Business / Other
4% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

1,240 h
Manual time on pending OAs
248 h
Time saved (low, 20%)
434 h
Time saved (mid, 35%)
10.8 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
POHNERT, STEVEN C 6 12.5% +18.2%
CROW, ROBERT THOMAS 6 41.6% +32.5%
YOUNG, BRIAN ELLIS 3 65.0% +28.3%
JONES, CHRISTINE MICHELLE 3 0.0% +0.0%
SCHULTZHAUS, JANNA NICOLE 3 35.4% +38.2%
PLAYER, ROBERT AUSTIN 3 13.6% +34.1%
WOITACH, JOSEPH T 3 49.5% +27.4%
WILDER, CYNTHIA B 2 70.8% +27.0%
MUI, CHRISTINE T 2 78.4% +19.8%
RILEY, JEZIA 2 83.0% +7.2%

Quick Wins (2)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
18650800 CONTROLLED POLYNUCLEOTIDE TRANSLOCATION IN NANOPORE SEQUENCING RILEY, JEZIA —
18393291 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES RILEY, JEZIA —

Hard Cases (75)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17250814 METHODS AND SYSTEMS FOR MONITORING ORGAN HEALTH AND DISEASE BAILEY, STEVEN WILLIAM 45d overdue
18300343 SYSTEM AND METHOD FOR SECONDARY ANALYSIS OF NUCLEOTIDE SEQUENCING DATA LIU, GUOZHEN 18d overdue
18534113 FLOW CELLS AND SEQUENCING KITS JONES, CHRISTINE MICHELLE 4d overdue
18129565 MACHINE LEARNING MODELING OF PROBE INTENSITY RODEN, DONALD THOMAS 3d overdue
17805138 SIGNAL-TO-NOISE-RATIO METRIC FOR DETERMINING NUCLEOTIDE-BASE CALLS AND BASE-CALL QUALITY KALLAL, ROBERT JAMES 12d
17813852 METHODS FOR PREPARING SUBSTRATE SURFACE FOR DNA SEQUENCING RAYMONDA, MATTHEW HAROLD 27d
18215641 NON-CONTACT DISPENSERS AND RELATED SYSTEMS AND METHODS LYLE, SOPHIA YUAN 34d
18987285 SEQUENCE DATA PROCESSING, RETENTION, AND RECOVERY HU, JENSEN 35d

Interview Candidates (28)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18176761 FUNCTIONALIZED NANOSTRUCTURES AND FLOW CELL DEPRESSIONS CROW, ROBERT THOMAS 24d overdue
17518135 SYSTEMS AND METHODS FOR MAKING SEQUENCING LIBRARIES YOUNG, BRIAN ELLIS 3d overdue
18885481 METHODS OF PREPARING LOOP FORK LIBRARIES YOUNG, BRIAN ELLIS 15d
17618836 METHODS FOR SEQUENCING POLYNUCLEOTIDES WILDER, CYNTHIA B 19d
18467770 NANOPARTICLE WITH POLYNUCLEOTIDE BINDING SITE AND METHOD OF MAKING THEREOF CROW, ROBERT THOMAS 29d
18343696 SEQUENCING NANOPARTICLES AND METHODS OF MAKING THE SAME CROW, ROBERT THOMAS 34d
18164341 Microfluidic Droplet Generators CROW, ROBERT THOMAS 34d
18760831 Anodized Metal Oxide Substrates Supporting Solid Support Feature Arrays for Patterned Flowcells WILDER, CYNTHIA B —

Top Art Units

Art UnitApps
1683 15
1684 13
1682 13
1687 12
1681 11
1685 10
1798 8
1686 7
2877 4
1797 3

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18987285 SEQUENCE DATA PROCESSING, RETENTION, AND RECOVERY HU, JENSEN 2169 §102§103 Non-Final OA 35d Pending Dec 19, 2024
18949085 MULTI-VERSION PROCESSING USING A MONITOR SUBSYSTEM GEORGANDELLIS, ANDREW C 2459 §103 Final Rejection — Pending Nov 15, 2024
18939115 AUTOFOCUS FUNCTIONALITY IN OPTICAL SAMPLE ANALYSIS AMARA, MOHAMED K 2877 §102§112 Non-Final OA — Pending Nov 06, 2024
18921425 DYNAMIC AUTOFOCUS METHOD AND SYSTEM FOR ASSAY IMAGER BRYANT, REBECCA CAROLE 2877 §103§112 Final Rejection — Pending Oct 21, 2024
18885481 METHODS OF PREPARING LOOP FORK LIBRARIES YOUNG, BRIAN ELLIS 1684 §103 Final Rejection 15d Pending Sep 13, 2024
18818453 ARTIFICIAL INTELLIGENCE-BASED QUALITY SCORING BHATNAGAR, ANAND P 2668 §101§102 Non-Final OA — Pending Aug 28, 2024
18808889 SYSTEMS AND DEVICES FOR SIGNAL CORRECTIONS IN SEQUENCING LEMIEUX, IAN L — §112 Final Rejection — Pending Aug 19, 2024
18795995 VALVE ASSEMBLIES AND RELATED SYSTEMS GZYBOWSKI, MICHAEL STANLEY 1798 §103 Non-Final OA — Pending Aug 06, 2024
18760831 Anodized Metal Oxide Substrates Supporting Solid Support Feature Arrays for Patterned Flowcells WILDER, CYNTHIA B 1681 §103 Non-Final OA — Pending Jul 01, 2024
18725694 IMAGING SYSTEMS AND RELATED SYSTEMS AND METHODS PEREZ-GUZMAN, CARLOS GABRIEL 2877 §103 Final Rejection 60d overdue Pending Jun 28, 2024
18759367 SYSTEMS AND RELATED REAGENT CARTRIDGE QUEUING METHODS WRIGHT, PATRICIA KATHRYN 1798 §103§112 Non-Final OA — Pending Jun 28, 2024
18758066 PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION POHNERT, STEVEN C 1683 §103§112 Non-Final OA — Pending Jun 28, 2024
18737223 METHOD FOR POLISHING A SUBSTRATE ISHAQ, ISHAQ MOHAMED SAID 3723 §103§112 Non-Final OA — Pending Jun 07, 2024
18732450 MULTI-VALVE FLUID CARTRIDGE MUI, CHRISTINE T 1797 §102Other Non-Final OA — Pending Jun 03, 2024
18664102 DIGITAL MICROFLUIDIC SYSTEM FOR SINGLE-CELL ISOLATION AND CHARACTERIZATION OF ANALYTES TSUI, YUNG-SHENG M 1684 §102§112DP Non-Final OA — Pending May 14, 2024
18650800 CONTROLLED POLYNUCLEOTIDE TRANSLOCATION IN NANOPORE SEQUENCING RILEY, JEZIA 1681 §102 Non-Final OA — Pending Apr 30, 2024
18633966 CAPTURING AND AMPLIFYING POLYNUCLEOTIDES CHUNDURU, SURYAPRABHA 1681 §102§112 Non-Final OA — Pending Apr 12, 2024
18618263 COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING CROW, ROBERT THOMAS 1683 §103§112 Non-Final OA — Pending Mar 27, 2024
18420482 INFERRING MICROORGANISM OF ORIGIN FOR ANTIMICROBIAL RESISTANCE MARKERS IN TARGETED METAGENOMICS MYERS, CARLA J 1671 §101§112 Non-Final OA — Pending Jan 23, 2024
18403902 MULTI-OMIC ANALYSIS IN MONODISPERSE DROPLETS KAPUSHOC, STEPHEN THOMAS 1683 §102§103DP Non-Final OA — Pending Jan 04, 2024
18575205 A CIRCUIT DESIGN TO MEASURE SMALL CURRENT VARIATION IN NANOPORE SEQUENCING BENZION, GARY 1681 §103 Final Rejection — Pending Dec 28, 2023
18575242 ANALOG CIRCUIT TO COMPENSATE BIAS OFFSET IN AMPLIFIER ARRAY SALMON, KATHERINE D 1682 §102§103§112 Non-Final OA — Pending Dec 28, 2023
18575254 NANOPORE SYSTEMS AND METHODS OF FABRICATION KAUR, GURPREET 1759 §103 Final Rejection — Pending Dec 28, 2023
18575265 DNA ORIGAMI STRUCTURE AND PROTEIN NANOPORE CONSTRUCT STAVROU, CONSTANTINA E 1632 §102§103 Non-Final OA — Pending Dec 28, 2023
18392547 METHODS OF SEQUENCING USING 3' ALLYL BLOCKED NUCLEOTIDES YOUNG, BRIAN ELLIS 1684 §101§103 Final Rejection — Pending Dec 21, 2023
18392826 DETECTION OF ANALYTES USING TARGETED EPIGENETIC ASSAYS, PROXIMITY-INDUCED TAGMENTATION, STRAND INVASION, RESTRICTION, OR LIGATION SWITZER, JULIET CAROLINE 1682 §112 Non-Final OA — Pending Dec 21, 2023
18572788 Well Assemblies and Related Systems and Methods KRCHA, MATTHEW D — §102§103 Non-Final OA — Pending Dec 21, 2023
18393291 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES RILEY, JEZIA 1681 DP Non-Final OA — Pending Dec 21, 2023
18389877 MULTI-SURFACE BIOLOGICAL SAMPLE IMAGING SYSTEM AND METHOD CROW, ROBERT THOMAS 1683 §103§112 Non-Final OA — Pending Dec 20, 2023
18572189 IMAGING SYSTEMS AND RELATED METHODS PHILLIPS, RUFUS L 2877 §103 Final Rejection 76d Pending Dec 20, 2023
18390578 PALLADIUM CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS BELLAH, JEFFREY LAWRENCE 1683 §103 Non-Final OA — Pending Dec 20, 2023
18571069 APTAMER DYNAMIC RANGE COMPRESSION AND DETECTION TECHNIQUES PHAM, KHAI QUYNH TIEN 1682 §103§112 Non-Final OA — Pending Dec 15, 2023
18542447 FLOW CELLS KASS, BENJAMIN JOSEPH 1798 §102§103§112 Non-Final OA — Pending Dec 15, 2023
18542470 FLOW CELLS BOWERS, NATHAN ANDREW 1799 §103§112 Non-Final OA — Pending Dec 15, 2023
18538441 Reusable Flow Cells Having Primer Binding Sites Comprising Reactive Sulfur Moieties and Methods of Using the Same, and Reagents for Use Therewith KOVACH, KARA NICOLE 1681 §103DP Non-Final OA — Pending Dec 13, 2023
18538262 ALTERED CYTIDINE DEAMINASES AND METHODS OF USE HUTSON, RICHARD G 1652 §103 Final Rejection 53d Pending Dec 13, 2023
18569421 CHARACTERIZING ANALYTES IN A SAMPLE USING NORMALIZED SIGNALS CRAWLEY, TALIA F — §102 Non-Final OA — Pending Dec 12, 2023
18535492 AUTOMATED VOLUMETRIC REAGENT DELIVERY TESTING WHATLEY, BENJAMIN R 1798 §101§102§103§112DPOther Final Rejection — Pending Dec 11, 2023
18568366 DETECTING METHYLCYTOSINE USING A MODIFIED BASE OPPOSITE TO THE METHYLCYTOSINE SALMON, KATHERINE D 1682 §102§103 Final Rejection — Pending Dec 08, 2023
18534113 FLOW CELLS AND SEQUENCING KITS JONES, CHRISTINE MICHELLE 1682 §103§112DP Final Rejection 4d overdue Pending Dec 08, 2023
18568756 PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES MARTIN, KEVIN STEPHEN 1681 §112Other Non-Final OA — Pending Dec 08, 2023
18567989 ORTHOGONAL HYBRIDIZATION PARISI, JESSICA DANIELLE 1682 §102§103§112 Non-Final OA — Pending Dec 07, 2023
18567697 METHODS AND COMPOSITIONS FOR COMBINATORIAL INDEXING OF BEAD-BASED NUCLEIC ACIDS RAYMONDA, MATTHEW HAROLD — §102§103§112 Non-Final OA — Pending Dec 06, 2023
18530865 NUCLEOSIDES AND NUCLEOTIDES WITH 3' BLOCKING GROUPS AND CLEAVABLE LINKERS CRAIGO, BAHAR ALAWI 1699 §112 Non-Final OA — Pending Dec 06, 2023
18530025 ETCH-FREE PHOTORESIST PATTERNING IN MULTI-DEPTH NANOWELLS GORDON, BRIAN R 1798 §102§103§112 Non-Final OA — Pending Dec 05, 2023
18566369 IDENTIFYING NUCLEOTIDES USING CHANGES IN IMPEDANCE BETWEEN ELECTRODES GRAY, JESSICA 1682 §101§103§112 Non-Final OA — Pending Dec 01, 2023
18523636 FLOW CELLS WITH PASSIVATION COMPONENTS ALABI, OYELEYE A 1797 §102§103 Non-Final OA — Pending Nov 29, 2023
18515013 REVERSIBLY CROSS-LINKED HYDROGELS, AND METHODS OF USING THE SAME FOR CLUSTER AMPLIFICATION YU, TIAN NMN 1681 §103 Final Rejection — Pending Nov 20, 2023
18562095 OLIGO-MODIFIED NUCLEOTIDE ANALOGUES FOR NUCLEIC ACID PREPARATION VANHORN, ABIGAIL LOUISE 1636 §102§103§112 Non-Final OA — Pending Nov 17, 2023
18507414 DESIGNING PROBES FOR DEPLETING ABUNDANT TRANSCRIPTS POHNERT, STEVEN C 1683 §101§103§112 Non-Final OA — Pending Nov 13, 2023

View all 124 →

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Frequently Asked Questions

How many pending USPTO office actions does Illumina Inc. have?

Illumina Inc. has 124 pending office actions as of October 2026, spread across 31 art units and 86 examiners.

Which USPTO examiner handles the most Illumina Inc. applications?

Steven C Pohnert has the most, with 6 of Illumina Inc.'s pending office actions.

What technology area are Illumina Inc.'s patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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