Prosecution Insights
Last updated: October 27, 2026

Guozhen Liu, USPTO Patent Examiner

Listed by the USPTO as LIU, GUOZHEN

Tech Center 1600 • Art Units: 1631 1672 1686

This examiner grants 48% of resolved cases

Analysis

LIU, GUOZHEN is a USPTO patent examiner in Tech Center 1600 and Art Unit 1631. The record includes 106 resolved cases, a 48.1% allowance rate, and a median of 1595 days to allowance. The allowance result reflects a mixed record, while the median timing indicates a lengthy prosecution path for matters reaching allowance.

The interview lift is 26.0%, showing a meaningful association between interviews and allowance outcomes. The listed companies are Grail, NantWorks, and Inocras Korea. The listed firms are Banner & Witcoff, Kilpatrick Townsend & Stockton, and Novick Kim & Lee. Practitioners may benefit from early issue identification, focused interview preparation, and careful management of extended response timelines.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

48.1%
Allow Rate
-11.9% vs TC avg
148
Total Applications
+26.0%
Interview Lift
1595
Avg Prosecution Days
Based on 106 resolved cases, 2023–2026

Rejection Statute Breakdown

39.0%
§101 Eligibility
7.0%
§102 Novelty
27.7%
§103 Obviousness
20.2%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
16340738 METHOD AND APPARATUS FOR IMPROVED DETERMINATION OF NODE INFLUENCE IN A NETWORK Final Rejection UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
18397262 METHOD FOR CREATING CELL MATHEMATICAL MODEL, CELL MATHEMATICAL MODEL CREATION PROGRAM, CELL MATHEMATICAL MODEL CREATION APPARATUS, METHOD FOR DETERMINING CELL MATHEMATICAL MODEL, CELL MATHEMATICAL MODEL DETERMINATION PROGRAM, AND CELL MATHEMATICAL MODEL DETERMINATION APPARATUS Non-Final OA FUJIFILM Corporation
17204836 COUPLED MATRIX-MATRIX AND COUPLED TENSOR-MATRIX COMPLETION METHODS FOR PREDICTING DRUG-TARGET INTERACTIONS Non-Final OA THE REGENTS OF THE UNIVERSITY OF MICHIGAN
18474797 Cancer Score for Assessment and Response Prediction from Biological Fluids Non-Final OA Nantomics LLC
18465868 Cancer Score for Assessment and Response Prediction from Biological Fluids Non-Final OA Nantomics, LLC
18027260 METHOD, APPARATUS AND DEVICE FOR IDENTIFYING SOURCE PRIMER OF NONSPECIFIC AMPLICATION SEQUENCE Non-Final OA BOE Technology Group Co., Ltd.
16341368 METHOD AND APPARATUS FOR COMPACT REPRESENTATION OF BIOINFORMATICS DATA Final Rejection KONINKLIJKE PHILIPS N.V.
18655208 EFFICIENT CLUSTERING OF NOISY POLYNUCLEOTIDE SEQUENCE READS Final Rejection MICROSOFT TECHNOLOGY LICENSING, LLC
17449952 DATA SIFTING METHOD AND APPARATUS Non-Final OA DELTA ELECTRONICS, INC.
18298690 Denoising ATAC-Seq Data With Deep Learning Final Rejection NVIDIA Corporation
18264055 METHOD AND SYSTEM FOR DESIGNING PERSONALIZED THERAPEUTICS AND DIET BASED ON FUNCTIONS OF MICROBIOME Non-Final OA Tata Consultancy Services Limited
18021377 MACHINE LEARNING-BASED VARIANT EFFECT ASSESSMENT AND USES THEREOF Non-Final OA Inari Agriculture Technology, Inc.
17557691 AFFINITY PREDICTION METHOD AND APPARATUS, METHOD AND APPARATUS FOR TRAINING AFFINITY PREDICTION MODEL, DEVICE AND MEDIUM Non-Final OA BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
17313449 RESOLUTION INDICES FOR DETECTING HETEROGENEITY IN DATA AND METHODS OF USE THEREOF Final Rejection Becton, Dickinson and Company
17092975 BACTERIAL CAPTURE SEQUENCING PLATFORM AND METHODS OF DESIGNING, CONSTRUCTING AND USING Final Rejection THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
17289882 Quantitative Algorithm for Endometriosis Final Rejection YALE UNIVERSITY
18670687 METHODS FOR DETECTING VARIANTS IN NEXT-GENERATION SEQUENCING GENOMIC DATA Non-Final OA Sophia Genetics S.A.
18300343 SYSTEM AND METHOD FOR SECONDARY ANALYSIS OF NUCLEOTIDE SEQUENCING DATA Final Rejection ILLUMINA, INC.

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Frequently Asked Questions

What is examiner Guozhen Liu's allowance rate?

48.1% of resolved applications examined by Guozhen Liu were allowed (106 resolved cases), compared with 28.4% across Art Unit 1631 over the last five years.

Does an interview help with examiner Guozhen Liu?

This examiner's interview lift is +26.0 percentage points: the difference in allowance rate between resolved applications that had an examiner interview and those that did not.

How long does examiner Guozhen Liu take to allow a patent?

Applications allowed by Guozhen Liu took 1,595 days on average from filing to allowance.

Which art unit does examiner Guozhen Liu work in?

Guozhen Liu examines applications in Art Unit 1631 in Tech Center 1600 (Biotechnology & Pharmaceuticals).

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