Prosecution Insights
Last updated: October 25, 2026

Insilico Medicine Ip Limited

Technology area: Biotechnology & Pharmaceuticals

12 pending office actions • 10 art units • 11 examiners • 0 of 12 (0%) have an AI response strategy ready • 5 patents granted in the last 365 days

Analysis

Insilico Medicine Ip Limited has 15 pending office actions in the Biotechnology & Pharmaceuticals technology area. These actions are handled by 13 distinct examiners, indicating that most examiners are managing a single case while a small number handle more. The prosecution is spread across 11 distinct art units, reflecting a diverse range of technical subject matter within the pharmaceutical sector. This distribution requires the applicant to manage multiple prosecution timelines simultaneously.

The busiest examiner for this portfolio is WILLIS, DOUGLAS M, who is responsible for 2 pending office actions. This examiner's workload represents a small portion of the 15 pending office actions currently active. Because the 13 distinct examiners operate across 11 distinct art units, practitioners must coordinate responses that are consistent across multiple specialized groups within the USPTO. The concentration of 2 pending office actions under WILLIS, DOUGLAS M provides a minor opportunity for streamlined communication.

With 15 pending office actions, the company faces a significant administrative challenge in maintaining a cohesive patent strategy. The involvement of 13 distinct examiners means that the company must be prepared for 13 unique approaches to prior art and obviousness rejections. Because the 15 pending office actions are spread across 11 distinct art units, practitioners must monitor for potential conflicts in prosecution across different technical divisions. This broad distribution underscores the complexity of the company's current engagement with the USPTO.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

12
Total Pending OAs
9
Non-Final OAs
3
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 3 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

1
Overdue
0
Due this week
1
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 3 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (1)Due ≤ 30 days (1)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

6
Hard (50%)
5
Medium (42%)
1
Easy (8%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other5 (42%)
§103 only4 (33%)
Double-patenting only1 (8%)
Double-patenting + other1 (8%)
Multi-statute (no §101)1 (8%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

9
Life Sciences
75% of docket
2
Information Tech
17% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
8% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

120 h
Manual time on pending OAs
24 h
Time saved (low, 20%)
42 h
Time saved (mid, 35%)
1.1 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
KALLAL, ROBERT JAMES 2 59.4% +31.2%
DAVIS, BRIAN J 1 84.8% -3.9%
ROBINSON, MIKHAIL O'DONNEL 1 58.3% +43.1%
CORNET, JEAN P 1 41.9% +47.2%
HIBSHMAN, SARAH GRACE 1 38.2% +40.7%
HASTINGS, ALISON AZAR 1 62.5% +42.1%
O DELL, DAVID K 1 57.7% +36.0%
SKIBINSKY, ANNA 1 39.1% +29.3%
BRACERO, ANDREW ANGEL 1 82.4% +37.5%
LUO, JAMMY NMN 1 — —

Quick Wins (2)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
17800129 ADVERSARIAL AUTOENCODER ARCHITECTURE FOR METHODS OF GRAPH TO SEQUENCE MODELS BRACERO, ANDREW ANGEL 33d
18928814 BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES DAVIS, BRIAN J —

Hard Cases (6)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
17596888 SYNTHETIC BIOLOGICAL CHARACTERISTIC GENERATOR BASED ON REAL BIOLOGICAL DATA SIGNATURES KALLAL, ROBERT JAMES 25d overdue
17911376 RETROSYNTHESIS-RELATED SYNTHETIC ACCESSIBILITY SKIBINSKY, ANNA 21d
18721283 METHOD AND MEDICAMENT FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS HIBSHMAN, SARAH GRACE —
18164160 LOCAL STEPS IN LATENT SPACE AND DESCRIPTORS-BASED MOLECULES FILTERING FOR CONDITIONAL MOLECULAR GENERATION KALLAL, ROBERT JAMES —
17835167 ADVERSARIAL FRAMEWORK FOR MOLECULAR CONFORMATION SPACE MODELING IN INTERNAL COORDINATES LUO, JAMMY NMN —
17479892 METHYLATION DATA SIGNATURES OF AGING AND METHODS OF DETERMINING A METHYLATION AGING CLOCK VANNI, GEORGE STEVEN —

Interview Candidates (9)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17596888 SYNTHETIC BIOLOGICAL CHARACTERISTIC GENERATOR BASED ON REAL BIOLOGICAL DATA SIGNATURES KALLAL, ROBERT JAMES 25d overdue
17911376 RETROSYNTHESIS-RELATED SYNTHETIC ACCESSIBILITY SKIBINSKY, ANNA 21d
17800129 ADVERSARIAL AUTOENCODER ARCHITECTURE FOR METHODS OF GRAPH TO SEQUENCE MODELS BRACERO, ANDREW ANGEL 33d
18837846 MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF ROBINSON, MIKHAIL O'DONNEL —
18832564 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP1) INHIBITORS AND USES THEREOF CORNET, JEAN P —
18721283 METHOD AND MEDICAMENT FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS HIBSHMAN, SARAH GRACE —
18705742 SARS-COV-2 INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS HASTINGS, ALISON AZAR —
18704366 PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF O DELL, DAVID K —

Top Art Units

Art UnitApps
1686 2
1614 1
1627 1
1693 1
1629 1
1621 1
2146 1
1635 1
2126 1
1685 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18928814 BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES DAVIS, BRIAN J 1614 §112DP Non-Final OA — Pending Oct 28, 2024
18837846 MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF ROBINSON, MIKHAIL O'DONNEL 1627 §103 Non-Final OA — Pending Aug 12, 2024
18832564 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP1) INHIBITORS AND USES THEREOF CORNET, JEAN P — §103 Non-Final OA — Pending Jul 24, 2024
18721283 METHOD AND MEDICAMENT FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS HIBSHMAN, SARAH GRACE 1693 §102§103§112 Non-Final OA — Pending Jun 18, 2024
18705742 SARS-COV-2 INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS HASTINGS, ALISON AZAR 1629 §103Other Final Rejection — Pending Apr 29, 2024
18704366 PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF O DELL, DAVID K 1621 DP Non-Final OA — Pending Apr 24, 2024
18164160 LOCAL STEPS IN LATENT SPACE AND DESCRIPTORS-BASED MOLECULES FILTERING FOR CONDITIONAL MOLECULAR GENERATION KALLAL, ROBERT JAMES 2146 §101§103§112 Non-Final OA — Pending Feb 03, 2023
17911376 RETROSYNTHESIS-RELATED SYNTHETIC ACCESSIBILITY SKIBINSKY, ANNA 1635 §101§103 Final Rejection 21d Pending Sep 13, 2022
17800129 ADVERSARIAL AUTOENCODER ARCHITECTURE FOR METHODS OF GRAPH TO SEQUENCE MODELS BRACERO, ANDREW ANGEL 2126 §103 Non-Final OA 33d Pending Aug 16, 2022
17835167 ADVERSARIAL FRAMEWORK FOR MOLECULAR CONFORMATION SPACE MODELING IN INTERNAL COORDINATES LUO, JAMMY NMN 1686 §101§103 Final Rejection — Pending Jun 08, 2022
17596888 SYNTHETIC BIOLOGICAL CHARACTERISTIC GENERATOR BASED ON REAL BIOLOGICAL DATA SIGNATURES KALLAL, ROBERT JAMES 1685 §101§112 Non-Final OA 25d overdue Pending Dec 20, 2021
17479892 METHYLATION DATA SIGNATURES OF AGING AND METHODS OF DETERMINING A METHYLATION AGING CLOCK VANNI, GEORGE STEVEN 1686 §101§112DP Non-Final OA — Pending Sep 20, 2021

Managing Insilico Medicine Ip Limited's Patent Portfolio?

IP Author helps IP teams respond to office actions faster with AI-generated responses, examiner analytics, and prosecution intelligence.

Start Free Trial

Frequently Asked Questions

How many pending USPTO office actions does Insilico Medicine Ip Limited have?

Insilico Medicine Ip Limited has 12 pending office actions as of October 2026, spread across 10 art units and 11 examiners.

Which USPTO examiner handles the most Insilico Medicine Ip Limited applications?

Robert James Kallal has the most, with 2 of Insilico Medicine Ip Limited's pending office actions.

What technology area are Insilico Medicine Ip Limited's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month