Prosecution Insights
Last updated: May 29, 2026

Iovance Biotherapeutics, Inc.

14 pending office actions • 10 art units • 14 examiners • 0 of 14 (0%) have an AI response strategy ready • 17 patents granted in the last 365 days

Portfolio Summary

14
Total Pending OAs
5
Non-Final OAs
5
Final Rejections
4
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 13 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

4
Overdue
0
Due this week
5
Due this month
2
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 13 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (4)Due ≤ 30 days (5)Due ≤ 60 days (2)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

1
Hard (7%)
6
Medium (43%)
0
Easy (0%)
7
Unknown (50%)

Rejection Statute Mix

BucketCases
§101 only1 (7%)
§103 only4 (29%)
Double-patenting + other2 (14%)
No statute on record7 (50%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

13
Life Sciences
93% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
1
Mechanical / Eng
7% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

140 h
Manual time on pending OAs
28 h
Time saved (low, 20%)
49 h
Time saved (mid, 35%)
1.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
MOSELEY II, NELSON B 1 68.1% +41.7%
DRISCOLL, MAUREEN VARINA 1 68.0% +35.3%
YAMASAKI, ROBERT J 1 67.5% +42.9%
STONEBRAKER, ALYSSA RAE 1 54.4% +52.8%
HUYNH, EMILY 1 19.5% +40.1%
WEN, SHARON X 1 56.5% +32.8%
CUNNINGCHEN, KATHLEEN MARY 1 63.8% +59.5%
AEDER, SEAN E 1 56.9% +19.6%
ZHU, JIANJIAN 1 59.7% +82.5%
KELLY, ROBERT M 1 74.1% +24.6%

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18590860 SYSTEMS AND METHODS FOR COORDINATING MANUFACTURING OF CELLS FOR PATIENT-SPECIFIC IMMUNOTHERAPY HUYNH, EMILY 16d

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18674418 EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES FROM LIQUID TUMORS AND THERAPEUTIC USES THEREOF YAMASAKI, ROBERT J 117d overdue
19011427 TIL EXPANSION FROM FINE NEEDLE ASPIRATES AND SMALL BIOPSIES MOSELEY II, NELSON B 92d overdue
18256853 TREATMENT OF CANCERS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES CUNNINGCHEN, KATHLEEN MARY 1d overdue
18590860 SYSTEMS AND METHODS FOR COORDINATING MANUFACTURING OF CELLS FOR PATIENT-SPECIFIC IMMUNOTHERAPY HUYNH, EMILY 16d
18262843 ADJUVANT THERAPY FOR CANCER WEN, SHARON X 20d
17829087 RESTIMULATION OF CRYOPRESERVED TUMOR INFILTRATING LYMPHOCYTES KELLY, ROBERT M 23d
17997731 PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF THE SAME IN IMMUNOTHERAPY ZHU, JIANJIAN 29d
18247877 TREATMENT OF NSCLC PATIENTS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES AEDER, SEAN E 33d

Top Art Units

Art UnitApps
1642 3
1646 2
1638 2
1644 1
1657 1
3683 1
1641 1
1631 1
1633 1
1632 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19011427 TIL EXPANSION FROM FINE NEEDLE ASPIRATES AND SMALL BIOPSIES MOSELEY II, NELSON B 1642 §103 Non-Final OA 92d overdue Pending Jan 06, 2025
18886988 TREATMENT WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES IN COMBINATION WITH CTLA-4 AND PD-1 INHIBITORS DRISCOLL, MAUREEN VARINA 1644 DPOther Final Rejection Pending Sep 16, 2024
18674418 EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES FROM LIQUID TUMORS AND THERAPEUTIC USES THEREOF YAMASAKI, ROBERT J 1657 §103 Non-Final OA 117d overdue Pending May 24, 2024
18673083 TREATMENT OF NSCLC PATIENTS REFRACTORY FOR ANTI-PD-1 ANTIBODY STONEBRAKER, ALYSSA RAE 1642 Other Final Rejection 55d Pending May 23, 2024
18590860 SYSTEMS AND METHODS FOR COORDINATING MANUFACTURING OF CELLS FOR PATIENT-SPECIFIC IMMUNOTHERAPY HUYNH, EMILY 3683 §101 Final Rejection 16d Pending Feb 28, 2024
18262843 ADJUVANT THERAPY FOR CANCER WEN, SHARON X 1641 Other Non-Final OA 20d Pending Jul 25, 2023
18256853 TREATMENT OF CANCERS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES CUNNINGCHEN, KATHLEEN MARY 1646 Other Non-Final OA 1d overdue Pending Jun 09, 2023
18247877 TREATMENT OF NSCLC PATIENTS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES AEDER, SEAN E 1642 Other Non-Final OA 33d Pending Apr 04, 2023
17997731 PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF THE SAME IN IMMUNOTHERAPY ZHU, JIANJIAN 1631 Other Non-Final OA 29d Pending Nov 01, 2022
17829087 RESTIMULATION OF CRYOPRESERVED TUMOR INFILTRATING LYMPHOCYTES KELLY, ROBERT M 1638 Other Non-Final OA 23d Pending May 31, 2022
17267699 Expansion of TILs from Cryopreserved Tumor Samples O'NEILL, MARISOL ANN 1633 §103 Final Rejection 12d Pending Jan 10, 2022
17610671 METHODS AND COMPOSITIONS FOR SELECTING TUMOR INFILTRATING LYMPHOCYTES AND USES OF THE SAME IN IMMUNOTHERAPY AMICK, THOMAS RUSSE 1638 DPOther Non-Final OA 70d Pending Nov 11, 2021
17420787 SYSTEM AND METHODS FOR MONITORING ADOPTIVE CELL THERAPY CLONALITY AND PERSISTENCE BEHARRY, ZANNA MARIA 1632 §103 Final Rejection 79d Pending Jul 06, 2021
17290705 SELECTION OF IMPROVED TUMOR REACTIVE T-CELLS REDDIG, PETER J 1646 Other Non-Final OA 259d overdue Pending Apr 30, 2021

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