Prosecution Insights
Last updated: October 02, 2026

Examiner: AEDER, SEAN E

Tech Center 1600 • Art Units: 1600 1642 1652 1654 1671

This examiner grants 57% of resolved cases

Analysis

Sean E. Aeder is a highly experienced examiner in Tech Center 1600, having resolved 1431 cases. His allowance rate of 57.0% indicates a moderate level of difficulty for applicants, with just over half of the 1431 cases reaching a grant. This 57.0% rate is based on a very large sample size, making it a reliable indicator of the examiner's general tendencies. Practitioners should prepare for a thorough examination process given this volume of work.

The interview lift is 19.9%, which suggests that interviews are a beneficial strategy for improving allowance odds. This 19.9% lift indicates that direct communication with the examiner can help resolve issues more effectively than written responses alone. The median days to allowance is 1124, providing a clear timeframe for successful prosecution. This 1124-day median, combined with the 19.9% lift, suggests that while the process may take time, active engagement can significantly enhance the 57.0% chance of success.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

57.0%
Allow Rate
-3.0% vs TC avg
1,495
Total Applications
+19.9%
Interview Lift
1124
Avg Prosecution Days
Based on 1431 resolved cases, 2023–2026

Rejection Statute Breakdown

14.7%
§101 Eligibility
17.1%
§102 Novelty
26.5%
§103 Obviousness
27.2%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
18746198 DETECTING NEOPLASM Non-Final OA Mayo Foundation for Medical Education and Research
18359569 LDL RECEPTOR-DIRECTED BISPECIFIC BINDING AGENT-LIGAND FUSIONS FOR THE DEGRADATION OF TARGET PROTEINS Non-Final OA The Regents of the University of California
18030223 ENHANCEMENT OF ANTI-TUMOR PHAGOCYTOSIS Final Rejection The Board of Trustees of the Leland Stanford Junior University
18042441 METHODS OF TREATING CANCER BY ADMINISTERING A PD-1 INHIBITOR Non-Final OA Regeneron Pharmaceuticals, Inc.
18010580 BIOMARKER BASED PATIENT SELECTION FOR PROTEASOME INHIBITOR TREATMENT Non-Final OA University of Utah Research Foundation
18193917 METHODS FOR THE DETECTION AND TREATMENT OF LUNG CANCER Non-Final OA Board of Regents, The University of Texas System
18528327 NATURAL KILLER T CELL LIGAND LOADED EXTRACELLULAR NANOVESICLE AND AUTOLOGOUS ANTI-CANCER VACCINE FOR HEMATOLOGIC MALIGNANCIES COMPRISING THE SAME Non-Final OA SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
18683858 OFATUMUMAB FOR TREATING PEDIATRIC MS Non-Final OA NOVARTIS AG
17753632 TREATMENT OF RMS BY SWITCHING THERAPY Non-Final OA Novartis AG
18018807 PHARMACEUTICAL COMPOSITION COMPRISING CELL EXPRESSING CHIMERIC RECEPTOR Final Rejection Yamaguchi University
17779716 COMPOSITIONS AND METHODS FOR TREATING DISEASES AND CONDITIONS BY DEPLETION OF MITOCHONDRIAL OR GENOMIC DNA FROM CIRCULATION Final Rejection Cedars-Sinai Medical Center
18286721 COMPOSITIONS AND METHODS FOR TREATING CHRONIC ACTIVE WHITE MATTER LESIONS / RADIOLOGICALLY ISOLATED SYNDROME Non-Final OA BIOGEN MA INC.
18122194 METHODS OF TREATING GLIOBLASTOMA Non-Final OA Ramot at Tel-Aviv University Ltd.
17918479 TARGETING ABCB5 IN GLIOBLASTOMA MULTIFORME Non-Final OA The Brigham and Women's Hospital, Inc.
17294401 COMPOSITIONS AND METHODS FOR THE CYTOPLASMIC DELIVERY OF ANTIBODIES AND OTHER PROTEINS Final Rejection THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
18247878 TREATMENT OF NSCLC PATIENTS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES Non-Final OA Iovance Biotherapeutics, Inc.
18563581 IMMUNE CHECKPOINT INHIBITOR AND HDAC INHIBITOR COMBINATION THERAPY STRATEGY Final Rejection H. Lee Moffitt Cancer Center and Research Institute, Inc.
18365369 Method for Determining Prognosis of Cancer Non-Final OA Queen Mary University of London
18549346 MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN THERAPY Non-Final OA BIONTECH SE
18392902 METHODS FOR DELIVERING ANTIBODIES TO THE FETAL CIRCULATION Final Rejection The Children's Medical Center Corporation
17642935 ATP-BASED CELL SORTING AND HYPERPROLIFERATIVE CANCER STEM CELLS Non-Final OA LUNELLA BIOTECH, INC.
18587839 HETERODIMERIC ANTIBODIES THAT BIND CD3 AND TUMOR ANTIGENS Final Rejection Xencor, Inc.
18691267 OPTIMIZED MULTABODY CONSTRUCTS, COMPOSITIONS, AND METHODS Non-Final OA Radiant Biotherapeutics Inc.
18249957 PVRL2 AND/OR PVRIG AS BIOMARKERS FOR TREATMENT Non-Final OA COMPUGEN LTD.
18024471 ANTI-CD47 MONOCLONAL ANTIBODY AND USE THEREOF Final Rejection Akeso Pharmaceuticals, Inc.
18256191 DIAGNOSTIC METHOD FOR MULTIPLE SCLEROSIS Non-Final OA Belgian Volition SRL (BE/BE)
18252904 NEAR INFRARED-II PROBES AS HIGH AFFINITY TARGETING IMAGING AGENTS AND USES THEREOF Non-Final OA On Target Laboratories, LLC
17916068 REDUCED CALORIC INTAKE AND IMMUNOTHERAPY FOR THE TREATMENT OF CANCER Non-Final OA IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE
17790278 METHOD FOR TREATING GASTRIC CANCER BY BLOCKING CCL28 CHEMOTACTIC PATHWAY Final Rejection CHANGEN THERAPEUTICS (SHANGHAI) CO., LTD.

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