Prosecution Insights
Last updated: October 27, 2026

Roche Sequencing Solutions Inc.

Technology areas: Biotechnology & Pharmaceuticals • Chemistry & Materials

25 pending office actions • 12 art units • 21 examiners • 0 of 25 (0%) have an AI response strategy ready • 23 patents granted in the last 365 days

Analysis

Roche Sequencing Solutions Inc. has 29 pending office actions in Biotechnology & Pharmaceuticals. The portfolio spans 26 distinct examiners and 14 distinct art units, showing substantial examiner diversity across a defined group of biotechnology examination areas.

QIAN, SHIZHI is the busiest listed examiner, with 2 pending matters. The limited concentration means that counsel should manage the docket through coordinated technology and disclosure positions, while maintaining separate records for the many examiner assignments.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

25
Total Pending OAs
21
Non-Final OAs
3
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 5 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

5
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 5 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (5)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

13
Hard (52%)
7
Medium (28%)
4
Easy (16%)
1
Unknown (4%)

Rejection Statute Mix

BucketCases
§101 + other6 (24%)
§103 only3 (12%)
§112 only1 (4%)
Double-patenting only3 (12%)
Double-patenting + other4 (16%)
Multi-statute (no §101)7 (28%)
No statute on record1 (4%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

24
Life Sciences
96% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
4% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

250 h
Manual time on pending OAs
50 h
Time saved (low, 20%)
88 h
Time saved (mid, 35%)
2.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
QIAN, SHIZHI 3 62.0% +46.2%
CROW, ROBERT THOMAS 2 41.6% +32.5%
BOESEN, CHRISTIAN C 2 76.0% +21.1%
JOHNSON, CHRISTINA ANN 1 41.3% -13.4%
SWIFT, CANDICE LEE 1 56.6% +37.2%
GIERE, REBECCA M 1 73.7% +32.3%
BUCCINI, MICHELLE CALLAHAN 1 — —
BELLAH, JEFFREY LAWRENCE 1 100.0% +0.0%
BROWN, MINDY G 1 57.8% +40.5%
DEES, NIKKI H 1 22.0% +20.7%

Hard Cases (13)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17805511 COMPUTING DEVICE WITH IMPROVED USER INTERFACE FOR INTERPRETING AND VISUALIZING DATA ANDERSON-FEARS, KEENAN NEIL 32d overdue
18214232 TUNNELING JUNCTIONS FOR SEQUENCING WALLENHORST, MAUREEN 3d overdue
18862479 COMPOSITIONS AND METHODS THAT REDUCE PRUSSIAN BLUE FORMATION DURING NANOPORE SEQUENCING QIAN, SHIZHI —
18580302 ALPHA-HEMOLYSIN VARIANTS FORMING NARROW CHANNEL PORES AND USES THEREOF BUCCINI, MICHELLE CALLAHAN —
18535222 MOLECULAR DETECTION AND COUNTING USING NANOPORES BELLAH, JEFFREY LAWRENCE —
18465724 TARGETED NEXT-GENERATION SEQUENCING VIA ANCHORED PRIMER EXTENSION BROWN, MINDY G —
18279319 DEVICES AND METHODS FOR ELECTROPHORETIC EXTRACTION OF NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES DEES, NIKKI H —
18058487 SEQUENCE ALIGNMENT SYSTEMS AND METHODS TO IDENTIFY SHORT MOTIFS IN HIGH-ERROR SINGLE-MOLECULE READS DHARITHREESAN, NIDHI —

Interview Candidates (11)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17907362 DEVICES AND METHODS FOR SAMPLE ANALYSIS QIAN, SHIZHI 53d overdue
19049948 NANOPORE-BASED SEQUENCING WITH VARYING VOLTAGE STIMULUS QIAN, SHIZHI —
18862479 COMPOSITIONS AND METHODS THAT REDUCE PRUSSIAN BLUE FORMATION DURING NANOPORE SEQUENCING QIAN, SHIZHI —
18712051 THERMOSTABLE POLYMERASE VARIANTS SWIFT, CANDICE LEE —
18612744 NANOPORE BASED MOLECULAR DETECTION AND SEQUENCING GIERE, REBECCA M —
18420048 CONCENTRATING A TARGET MOLECULE FOR SENSING BY A NANOPORE CROW, ROBERT THOMAS —
18465724 TARGETED NEXT-GENERATION SEQUENCING VIA ANCHORED PRIMER EXTENSION BROWN, MINDY G —
18279319 DEVICES AND METHODS FOR ELECTROPHORETIC EXTRACTION OF NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES DEES, NIKKI H —

Top Art Units

Art UnitApps
1795 5
1683 4
1682 2
1684 2
1686 2
1687 2
1681 2
1742 1
1657 1
1677 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19253275 OSMOTIC IMBALANCE METHODS FOR BILAYER FORMATION JOHNSON, CHRISTINA ANN 1742 DP Non-Final OA — Pending Jun 27, 2025
19049948 NANOPORE-BASED SEQUENCING WITH VARYING VOLTAGE STIMULUS QIAN, SHIZHI 1795 §112 Non-Final OA — Pending Feb 10, 2025
18862479 COMPOSITIONS AND METHODS THAT REDUCE PRUSSIAN BLUE FORMATION DURING NANOPORE SEQUENCING QIAN, SHIZHI 1795 §103§112 Non-Final OA — Pending Nov 01, 2024
18712051 THERMOSTABLE POLYMERASE VARIANTS SWIFT, CANDICE LEE 1657 §102§112DP Non-Final OA — Pending May 21, 2024
18612744 NANOPORE BASED MOLECULAR DETECTION AND SEQUENCING GIERE, REBECCA M 1677 DP Non-Final OA — Pending Mar 21, 2024
18420048 CONCENTRATING A TARGET MOLECULE FOR SENSING BY A NANOPORE CROW, ROBERT THOMAS 1683 §112DP Non-Final OA — Pending Jan 23, 2024
18580302 ALPHA-HEMOLYSIN VARIANTS FORMING NARROW CHANNEL PORES AND USES THEREOF BUCCINI, MICHELLE CALLAHAN 1682 §102§112Other Non-Final OA — Pending Jan 18, 2024
18535222 MOLECULAR DETECTION AND COUNTING USING NANOPORES BELLAH, JEFFREY LAWRENCE 1683 §101§103DP Non-Final OA — Pending Dec 11, 2023
18465724 TARGETED NEXT-GENERATION SEQUENCING VIA ANCHORED PRIMER EXTENSION BROWN, MINDY G 1683 §101§102§103§112 Non-Final OA — Pending Sep 12, 2023
18279319 DEVICES AND METHODS FOR ELECTROPHORETIC EXTRACTION OF NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES DEES, NIKKI H 1691 §102§103 Non-Final OA — Pending Aug 29, 2023
18449216 IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT BOESEN, CHRISTIAN C — Other Non-Final OA — Pending Aug 14, 2023
18348235 TRANSLOCATION CONTROL FOR SENSING BY A NANOPORE CROW, ROBERT THOMAS 1683 §102§112DP Final Rejection — Pending Jul 06, 2023
18215555 Immuno-PETE BOESEN, CHRISTIAN C 1684 DP Non-Final OA — Pending Jun 28, 2023
18214232 TUNNELING JUNCTIONS FOR SEQUENCING WALLENHORST, MAUREEN 1797 §103§112 Final Rejection 3d overdue Pending Jun 26, 2023
18246009 DEVICES AND METHODS FOR URINE SAMPLE ANALYSIS SUN, CAITLYN MINGYUN 1795 §103 Non-Final OA — Pending Mar 20, 2023
18058484 NANOPORE CELL WITH SEAMLESS WORKING ELECTRODE AND METHODS OF FORMING THE SAME GAMBLE JR, RANDALL LEE 1795 §103 Non-Final OA 138d overdue Pending Nov 23, 2022
18058487 SEQUENCE ALIGNMENT SYSTEMS AND METHODS TO IDENTIFY SHORT MOTIFS IN HIGH-ERROR SINGLE-MOLECULE READS DHARITHREESAN, NIDHI 1686 §101§102§112 Non-Final OA — Pending Nov 23, 2022
17922222 A METHOD FOR DETECTING REACTION VOLUME DEVIATIONS IN A DIGITAL POLYMERASE CHAIN REACTION SANFORD, DIANA PATRICIA 1687 §101§103§112 Non-Final OA — Pending Oct 28, 2022
17907362 DEVICES AND METHODS FOR SAMPLE ANALYSIS QIAN, SHIZHI 1795 §103 Non-Final OA 53d overdue Pending Sep 26, 2022
17905784 NOVEL NUCLEIC ACID TEMPLATE STRUCTURE FOR SEQUENCING GIAMMONA, FRANCESCA FILIPPA 1681 §102§103 Non-Final OA — Pending Sep 07, 2022
17856923 CHEMICAL METHODS FOR PRODUCING TAGGED NUCLEOTIDES ZHANG, KAIJIANG 1684 §102§103 Non-Final OA — Pending Jul 01, 2022
17805511 COMPUTING DEVICE WITH IMPROVED USER INTERFACE FOR INTERPRETING AND VISUALIZING DATA ANDERSON-FEARS, KEENAN NEIL 1687 §101§103 Final Rejection 32d overdue Pending Jun 06, 2022
17756068 SYSTEMS AND METHODS FOR CONTAMINATION DETECTION IN NEXT GENERATION SEQUENCING SAMPLES SMITH, EMILIE ALINE 1686 §101§112 Non-Final OA — Pending May 16, 2022
17651135 SINGLE TUBE PREPARATION OF DNA AND RNA FOR SEQUENCING YU, TIAN NMN 1681 §102§103 Non-Final OA — Pending Feb 15, 2022
17595263 DEVICES AND METHODS FOR SAMPLE ANALYSIS DAUNER, JOSEPH G 1682 §103DP Non-Final OA 46d overdue Pending Nov 12, 2021

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Frequently Asked Questions

How many pending USPTO office actions does Roche Sequencing Solutions Inc. have?

Roche Sequencing Solutions Inc. has 25 pending office actions as of October 2026, spread across 12 art units and 21 examiners.

Which USPTO examiner handles the most Roche Sequencing Solutions Inc. applications?

Shizhi Qian has the most, with 3 of Roche Sequencing Solutions Inc.'s pending office actions.

What technology area are Roche Sequencing Solutions Inc.'s patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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