Prosecution Insights
Last updated: October 02, 2026

Sapreme Technologies B V

Technology area: Biotechnology & Pharmaceuticals

14 pending office actions • 8 art units • 11 examiners • 0 of 14 (0%) have an AI response strategy ready • 2 patents granted in the last 365 days

Analysis

Sapreme Technologies B V operates within the Biotechnology & Pharmaceuticals technology area with a portfolio containing 13 pending office actions. This workload is distributed among 11 distinct examiners, suggesting a broad engagement with the patent office. The involvement of 8 distinct art units further indicates that the company's research and development efforts span multiple specialized sub-sectors.

ZARA, JANE J is the busiest examiner for this portfolio, currently overseeing 2 pending office actions. While this examiner has the highest individual count, the presence of 11 distinct examiners means that most of the 13 pending actions are being reviewed by different officials. This distribution minimizes the impact of any single examiner's tendencies on the overall portfolio.

The presence of 8 distinct art units for 13 pending office actions shows some concentration of subject matter, though the presence of 11 distinct examiners relative to actions suggests a diverse prosecution landscape. Practitioners must coordinate strategies across these units to ensure consistency in the Biotechnology & Pharmaceuticals space. The reliance on 2 pending actions for the busiest examiner highlights the lack of central examiner control.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

14
Total Pending OAs
4
Non-Final OAs
9
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 7 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
3
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 7 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 30 days (3)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

4
Hard (29%)
9
Medium (64%)
1
Easy (7%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other1 (7%)
§103 only4 (29%)
Double-patenting only1 (7%)
Double-patenting + other5 (36%)
Multi-statute (no §101)3 (21%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

13
Life Sciences
93% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
7% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

140 h
Manual time on pending OAs
28 h
Time saved (low, 20%)
49 h
Time saved (mid, 35%)
1.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
ZARA, JANE J 2 71.0% +16.1%
HUYNH, PHUONG N 2 65.7% +53.6%
SKOKO III, JOHN JOSEPH 2 53.1% +58.2%
SU-TOBON, QIWEN NMN 1 66.7% +66.7%
CHONG, KIMBERLY 1 72.4% +13.0%
HIBSHMAN, SARAH GRACE 1 38.9% +40.0%
PUTTLITZ, KARL J 1 69.1% +18.6%
CREWS, JARET JAMES 1 44.7% +70.3%
CHO, DAVID H 1 31.9% +67.0%
LEE, HOI YAN NMN 1 38.4% +75.9%

Hard Cases (4)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
17312193 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS HUYNH, PHUONG N 22d
18564885 CYTOSOLIC DELIVERY OF GENOME EDITING TOOLS SU-TOBON, QIWEN NMN —
18012760 COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND AN ANTIBODY-SAPONIN CONJUGATE HUYNH, PHUONG N —
17312104 Saponin Conjugates BAKSHI, PANCHAM —

Interview Candidates (13)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17415759 DRUG CONJUGATE ZARA, JANE J 30d overdue
18044945 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC CHONG, KIMBERLY 9d overdue
18012694 SAPONIN DERIVATIVES FOR USE IN MEDICINE CREWS, JARET JAMES 1d overdue
18012710 CONJUGATE OF SAPONIN AND SINGLE-DOMAIN ANTIBODY, PHARMACEUTICAL COMPOSITION COMPRISING SAID CONJUGATE, THERAPEUTIC USE THEREOF PUTTLITZ, KARL J 14d
17312193 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS HUYNH, PHUONG N 22d
18012741 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE SKOKO III, JOHN JOSEPH 26d
17629598 BIOACTIVE SAPONIN LINKED TO A FUNCTIONAL MOIETY LEE, HOI YAN NMN 34d
18564885 CYTOSOLIC DELIVERY OF GENOME EDITING TOOLS SU-TOBON, QIWEN NMN —

Top Art Units

Art UnitApps
1693 3
1637 2
1641 2
1643 2
1636 1
1646 1
1691 1
1623 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18564885 CYTOSOLIC DELIVERY OF GENOME EDITING TOOLS SU-TOBON, QIWEN NMN — §101§102§103§112DP Non-Final OA — Pending Nov 28, 2023
18044945 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC CHONG, KIMBERLY 1636 §103§112DP Final Rejection 9d overdue Pending Mar 10, 2023
18012769 CONJUGATE OF GALNAC AND SAPONIN, THERAPEUTIC COMPOSITION COMPRISING SAID CONJUGATE AND A GALNAC-OLIGONUCLEOTIDE CONJUGATE ZARA, JANE J 1637 §112DP Non-Final OA — Pending Dec 23, 2022
18012791 HYDRAZONE-BASED SAPONIN DERIVATIVES HIBSHMAN, SARAH GRACE 1693 §103§112DP Non-Final OA — Pending Dec 23, 2022
18012710 CONJUGATE OF SAPONIN AND SINGLE-DOMAIN ANTIBODY, PHARMACEUTICAL COMPOSITION COMPRISING SAID CONJUGATE, THERAPEUTIC USE THEREOF PUTTLITZ, KARL J 1646 DP Final Rejection 14d Pending Dec 23, 2022
18012760 COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND AN ANTIBODY-SAPONIN CONJUGATE HUYNH, PHUONG N 1641 §103§112Other Final Rejection — Pending Dec 23, 2022
18012694 SAPONIN DERIVATIVES FOR USE IN MEDICINE CREWS, JARET JAMES 1691 §103 Final Rejection 1d overdue Pending Dec 23, 2022
18012729 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION CHO, DAVID H 1693 §103DP Final Rejection — Pending Dec 23, 2022
18012754 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE SKOKO III, JOHN JOSEPH 1643 §103Other Non-Final OA — Pending Dec 23, 2022
18012741 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE SKOKO III, JOHN JOSEPH 1643 §103Other Final Rejection 26d Pending Dec 23, 2022
17629598 BIOACTIVE SAPONIN LINKED TO A FUNCTIONAL MOIETY LEE, HOI YAN NMN 1693 §103Other Final Rejection 34d Pending Jan 24, 2022
17415759 DRUG CONJUGATE ZARA, JANE J 1637 §103§112DP Final Rejection 30d overdue Pending Jun 18, 2021
17312193 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS HUYNH, PHUONG N 1641 §103§112Other Final Rejection 22d Pending Jun 09, 2021
17312104 Saponin Conjugates BAKSHI, PANCHAM 1623 §102§112 Non-Final OA — Pending Jun 09, 2021

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