Prosecution Insights
Last updated: October 25, 2026

Seattle Children's Hospital (dba Seattle Children's Research Institute)

Technology area: Biotechnology & Pharmaceuticals

10 pending office actions • 7 art units • 9 examiners • 0 of 10 (0%) have an AI response strategy ready • 6 patents granted in the last 365 days

Analysis

Seattle Children's Hospital (dba Seattle Children's Research Institute) has 11 pending office actions in Biotechnology & Pharmaceuticals. The matters involve 10 examiners and 8 art units, showing broad examiner distribution with more limited art-unit distribution. Counsel needs centralized docket control and coordinated technical support, while allowing individual office actions to determine claim and prior-art strategy.

NGUYEN, QUANG is the busiest examiner, with 2 pending matters. The remaining actions are handled by other examiners, and the art-unit structure does not mirror the examiner distribution. Counsel should review the two matters assigned to this examiner together for consistency, while managing the other files through their own examination records.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

10
Total Pending OAs
4
Non-Final OAs
6
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 6 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
3
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 6 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 30 days (3)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

3
Hard (30%)
4
Medium (40%)
3
Easy (30%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only3 (30%)
§112 only2 (20%)
Double-patenting only1 (10%)
Double-patenting + other1 (10%)
Multi-statute (no §101)3 (30%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

10
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

100 h
Manual time on pending OAs
20 h
Time saved (low, 20%)
35 h
Time saved (mid, 35%)
0.9 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
NGUYEN, QUANG 2 37.9% +52.6%
GRABER, JAMES J 1 46.5% +57.6%
CUNNINGCHEN, KATHLEEN MARY 1 62.5% +60.5%
JONES-FOSTER, ERICA NICOLE 1 49.4% +44.0%
HAMA, JOANNE 1 25.4% +40.2%
HUYNH, PHUONG N 1 65.8% +53.6%
PYLA, EVELYN Y 1 55.8% +47.1%
BATES, KEENAN ALEXANDER 1 44.9% +79.8%
MARVICH, MARIA 1 55.0% +28.0%

Hard Cases (3)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 3 ordered by deadline are shown.

App #TitleExaminerDue in
18336248 METHOD FOR TREATING AUTOIMMUNE DISEASE USING CD4 T-CELLS WITH ENGINEERED STABILIZATION OF EXPRESSION OF ENDOGENOUS FOXP3 GENE CUNNINGCHEN, KATHLEEN MARY 26d
18000468 ANTI-CD171 CHIMERIC ANTIGEN RECEPTORS HAMA, JOANNE 28d
18441393 ENGRAFTABLE CELL-BASED IMMUNOTHERAPY FOR LONG-TERM DELIVERY OF THERAPEUTIC PROTEINS GRABER, JAMES J —

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18336276 EXPRESSION OF FOXP3 IN EDITED CD34+ CELLS NGUYEN, QUANG 157d overdue
17424140 MICROENVIRONMENT SENSORS TO REGULATE ENGINEERED GENE EXPRESSION BATES, KEENAN ALEXANDER 147d overdue
17931258 BISPECIFIC CAR T-CELLS FOR SOLID TUMOR TARGETING HUYNH, PHUONG N 16d overdue
18336248 METHOD FOR TREATING AUTOIMMUNE DISEASE USING CD4 T-CELLS WITH ENGINEERED STABILIZATION OF EXPRESSION OF ENDOGENOUS FOXP3 GENE CUNNINGCHEN, KATHLEEN MARY 26d
17811685 LONG POLY(A) PLASMIDS AND METHODS FOR INTRODUCTION OF LONG POLY(A) SEQUENCES INTO THE PLASMID PYLA, EVELYN Y 27d
18000468 ANTI-CD171 CHIMERIC ANTIGEN RECEPTORS HAMA, JOANNE 28d
18441393 ENGRAFTABLE CELL-BASED IMMUNOTHERAPY FOR LONG-TERM DELIVERY OF THERAPEUTIC PROTEINS GRABER, JAMES J —
18030476 METHODS AND COMPOSITIONS COMPRISING PD1 CHIMERIC POLYPEPTIDES JONES-FOSTER, ERICA NICOLE —

Top Art Units

Art UnitApps
1631 4
1646 1
1656 1
1647 1
1641 1
1633 1
1634 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18441393 ENGRAFTABLE CELL-BASED IMMUNOTHERAPY FOR LONG-TERM DELIVERY OF THERAPEUTIC PROTEINS GRABER, JAMES J 1631 §102§112 Non-Final OA — Pending Feb 14, 2024
18336248 METHOD FOR TREATING AUTOIMMUNE DISEASE USING CD4 T-CELLS WITH ENGINEERED STABILIZATION OF EXPRESSION OF ENDOGENOUS FOXP3 GENE CUNNINGCHEN, KATHLEEN MARY 1646 §102§103§112 Final Rejection 26d Pending Jun 16, 2023
18336276 EXPRESSION OF FOXP3 IN EDITED CD34+ CELLS NGUYEN, QUANG 1631 §103DP Non-Final OA 157d overdue Pending Jun 16, 2023
18030476 METHODS AND COMPOSITIONS COMPRISING PD1 CHIMERIC POLYPEPTIDES JONES-FOSTER, ERICA NICOLE 1656 §103 Non-Final OA — Pending Apr 05, 2023
18000468 ANTI-CD171 CHIMERIC ANTIGEN RECEPTORS HAMA, JOANNE 1647 §103§112 Non-Final OA 28d Pending Dec 01, 2022
17931258 BISPECIFIC CAR T-CELLS FOR SOLID TUMOR TARGETING HUYNH, PHUONG N 1641 DP Final Rejection 16d overdue Pending Sep 12, 2022
17811685 LONG POLY(A) PLASMIDS AND METHODS FOR INTRODUCTION OF LONG POLY(A) SEQUENCES INTO THE PLASMID PYLA, EVELYN Y 1633 §103 Final Rejection 27d Pending Jul 11, 2022
17424140 MICROENVIRONMENT SENSORS TO REGULATE ENGINEERED GENE EXPRESSION BATES, KEENAN ALEXANDER 1631 §103 Final Rejection 147d overdue Pending Jul 19, 2021
17050601 THERAPEUTIC GENOME EDITING IN X-LINKED HYPER IGM SYNDROME MARVICH, MARIA 1634 §112 Final Rejection — Pending Oct 26, 2020
16605740 OPTIMIZED LENTIVIRAL VECTOR FOR XLA GENE THERAPY NGUYEN, QUANG 1631 §112 Final Rejection — Pending Oct 16, 2019

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Frequently Asked Questions

How many pending USPTO office actions does Seattle Children's Hospital (dba Seattle Children's Research Institute) have?

Seattle Children's Hospital (dba Seattle Children's Research Institute) has 10 pending office actions as of October 2026, spread across 7 art units and 9 examiners.

Which USPTO examiner handles the most Seattle Children's Hospital (dba Seattle Children's Research Institute) applications?

Quang Nguyen has the most, with 2 of Seattle Children's Hospital (dba Seattle Children's Research Institute)'s pending office actions.

What technology area are Seattle Children's Hospital (dba Seattle Children's Research Institute)'s patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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