Prosecution Insights
Last updated: October 25, 2026

The Children's Medical Center Corporation

Technology area: Biotechnology & Pharmaceuticals

27 pending office actions • 21 art units • 27 examiners • 0 of 27 (0%) have an AI response strategy ready • 19 patents granted in the last 365 days

Analysis

The Children's Medical Center Corporation has 25 pending office actions in Biotechnology & Pharmaceuticals. The actions involve 25 examiners and 19 art units, demonstrating a widely distributed prosecution docket across both examiner assignments and examination units. No examiner accounts for more than the recorded busiest-examiner workload, so the portfolio is not organized around a dominant examination relationship.

SAMALA, JAGADISHWAR RAO handles 1 pending matter and is the busiest examiner. The broad spread requires matter-level prosecution planning, with response positions tailored to individual records rather than applied uniformly. The art-unit distribution also suggests that claim scope, prior-art analysis, and evidentiary needs may differ across applications.

Counsel can still benefit from coordinated technical narratives, disclosure review, and tracking of recurring objections. Shared strategies should function as a framework, while amendments and interview plans remain responsive to each examiner and art unit.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

27
Total Pending OAs
16
Non-Final OAs
10
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 9 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

6
Overdue
0
Due this week
1
Due this month
1
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 9 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (6)Due ≤ 30 days (1)Due ≤ 60 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

18
Hard (67%)
7
Medium (26%)
2
Easy (7%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other3 (11%)
§103 only4 (15%)
§112 only2 (7%)
Double-patenting + other3 (11%)
Multi-statute (no §101)15 (56%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

22
Life Sciences
81% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
5
Mechanical / Eng
19% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

270 h
Manual time on pending OAs
54 h
Time saved (low, 20%)
94 h
Time saved (mid, 35%)
2.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
SAMALA, JAGADISHWAR RAO 1 67.9% +55.7%
HIBBERT, CATHERINE S 1 58.8% +48.6%
SHIN, DANA H 1 26.9% +26.9%
KASSA, TIGABU 1 36.7% +27.9%
GEIGER, RACHAEL L 1 82.3% +18.3%
PAULUS, ERIN VIRGINIA 1 20.0% +94.1%
AEDER, SEAN E 1 56.9% +20.0%
GANESAN, SUBA 1 73.8% +13.4%
MARTIN, PAUL C 1 41.8% +21.7%
GABEL, GAILENE 1 75.6% +44.7%

Hard Cases (18)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17767340 METHODS AND COMPOSITIONS FOR TREATING ATAXIA TELANGIECTASIA MCLEOD, AFRICA MHAIRIE 89d overdue
18424292 COMPOUNDS AND METHODS FOR TREATMENT OF DIAMOND BLACKFAN ANEMIA PAULUS, ERIN VIRGINIA 45d overdue
18009645 USE OF HEAT SHOCK PROTEIN INHIBITORS FOR THE TREATMENT OF NEURODEVELOPMENTAL DISORDERS HUTTER, GILLIAN A 1d overdue
18320921 SURGICAL REPAIR SIMULATION DEVICES MCCLELLAN, JAMES S 21d
18703100 SUBCUTANEOUS ABRASION TREATMENT FOR STRETCH MARKS GEIGER, RACHAEL L 54d
18286405 CARDIOMYOCYTES AND COMPOSITIONS AND METHODS FOR PRODUCING THE SAME MARTIN, PAUL C 61d
18884967 USE OF ALVEOLAR OR AIRWAY ORGANOIDS FOR THE TREATMENT OF LUNG DISEASES AND DISORDERS SAMALA, JAGADISHWAR RAO —
18720551 ANTISENSE OLIGONUCLEOTIDES (ASOS) THAT SUPPRESS SARS-COV-2 REPLICATION SHIN, DANA H —

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18424292 COMPOUNDS AND METHODS FOR TREATMENT OF DIAMOND BLACKFAN ANEMIA PAULUS, ERIN VIRGINIA 45d overdue
18703100 SUBCUTANEOUS ABRASION TREATMENT FOR STRETCH MARKS GEIGER, RACHAEL L 54d
18286405 CARDIOMYOCYTES AND COMPOSITIONS AND METHODS FOR PRODUCING THE SAME MARTIN, PAUL C 61d
18884967 USE OF ALVEOLAR OR AIRWAY ORGANOIDS FOR THE TREATMENT OF LUNG DISEASES AND DISORDERS SAMALA, JAGADISHWAR RAO —
18835427 COMPOSITIONS AND METHODS RELATING TO ATP/P2X7R SIGNALING INHIBITION HIBBERT, CATHERINE S —
18720551 ANTISENSE OLIGONUCLEOTIDES (ASOS) THAT SUPPRESS SARS-COV-2 REPLICATION SHIN, DANA H —
18716692 COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF KASSA, TIGABU —
18392902 METHODS FOR DELIVERING ANTIBODIES TO THE FETAL CIRCULATION AEDER, SEAN E —

Top Art Units

Art UnitApps
1631 3
1635 2
1653 2
1634 2
3715 2
1618 1
1658 1
1619 1
3771 1
1642 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18884967 USE OF ALVEOLAR OR AIRWAY ORGANOIDS FOR THE TREATMENT OF LUNG DISEASES AND DISORDERS SAMALA, JAGADISHWAR RAO 1618 §102§103 Non-Final OA — Pending Sep 13, 2024
18835427 COMPOSITIONS AND METHODS RELATING TO ATP/P2X7R SIGNALING INHIBITION HIBBERT, CATHERINE S 1658 §102§103§112DP Non-Final OA — Pending Aug 02, 2024
18720551 ANTISENSE OLIGONUCLEOTIDES (ASOS) THAT SUPPRESS SARS-COV-2 REPLICATION SHIN, DANA H 1635 §102§103 Non-Final OA — Pending Jun 14, 2024
18716692 COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF KASSA, TIGABU 1619 §102§103 Non-Final OA — Pending Jun 05, 2024
18703100 SUBCUTANEOUS ABRASION TREATMENT FOR STRETCH MARKS GEIGER, RACHAEL L 3771 §102§103 Non-Final OA 54d Pending Apr 19, 2024
18424292 COMPOUNDS AND METHODS FOR TREATMENT OF DIAMOND BLACKFAN ANEMIA PAULUS, ERIN VIRGINIA 1631 §102§103§112 Final Rejection 45d overdue Pending Jan 26, 2024
18392902 METHODS FOR DELIVERING ANTIBODIES TO THE FETAL CIRCULATION AEDER, SEAN E 1642 §103 Final Rejection — Pending Dec 21, 2023
18520488 COLLAGEN SCAFFOLDS GANESAN, SUBA 3774 §103§112 Non-Final OA — Pending Nov 27, 2023
18286405 CARDIOMYOCYTES AND COMPOSITIONS AND METHODS FOR PRODUCING THE SAME MARTIN, PAUL C 1653 §102§103§112 Non-Final OA 61d Pending Oct 11, 2023
18549676 METHODS FOR DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE GABEL, GAILENE 1678 §101§102§103§112 Non-Final OA — Pending Sep 08, 2023
18236602 SYSTEMS FOR ANALYZING PATTERNS IN ELECTRODERMAL ACTIVITY RECORDINGS OF PATIENTS TO PREDICT SEIZURE LIKELIHOOD AND METHODS OF USE THEREOF GOMES, SRISTI DIVINA 3791 §101§103 Final Rejection — Pending Aug 22, 2023
18360505 COMPOSITIONS AND METHODS FOR TREATING CEREBROSPINAL FLUID DISORDERS POLIAKOVA-GEORGAN, EKATERINA 1637 §102§103 Non-Final OA — Pending Jul 27, 2023
18352730 COMPOSITIONS AND METHODS FOR NEUROPROTECTION AND/OR NEUROREGENERATION CANDELARIA, JULIANA IRENE 1634 §103§112 Non-Final OA — Pending Jul 14, 2023
18341584 COMPOSITIONS AND METHODS FOR TREATING DISEASES ASSOCIATED WITH AN IMPRINTING DEFECT ANDERSON, JAMES D 1629 §112 Non-Final OA 171d overdue Pending Jun 26, 2023
18206830 METHOD FOR TREATING CANCER REGLAS, GEORGIANA C 1651 §103§112 Non-Final OA — Pending Jun 07, 2023
18320927 SURGICAL REPAIR SIMULATION DEVICES HULL, JAMES B 3715 §103 Final Rejection 28d overdue Pending May 19, 2023
18320921 SURGICAL REPAIR SIMULATION DEVICES MCCLELLAN, JAMES S 3715 §102§103 Non-Final OA 21d Pending May 19, 2023
18016190 TARGETING ZNF410 FOR FETAL HEMOGLOBIN INDUCTION IN BETAHEMOGLOBINOPATHIES VANHORN, ABIGAIL LOUISE 1636 §112DP Non-Final OA — Pending Jan 13, 2023
18002633 METHODS AND COMPOSITIONS FOR TREATING MULTIPLE SCLEROSIS KIM, TAEYOON 1631 §103DP Final Rejection — Pending Dec 20, 2022
18011089 COMPOSITIONS AND METHODS FOR REGULATING ENTEROENDOCRINE CELL DIFFERENTIATION AND USES THEREOF VIJAYARAGHAVAN, JAGAMYA NMN 1633 §103§112 Final Rejection — Pending Dec 16, 2022
18009645 USE OF HEAT SHOCK PROTEIN INHIBITORS FOR THE TREATMENT OF NEURODEVELOPMENTAL DISORDERS HUTTER, GILLIAN A 1625 §102§103 Final Rejection 1d overdue Pending Dec 09, 2022
18074107 TARGETING BCL11A DISTAL REGULATORY ELEMENTS FOR FETAL HEMOGLOBIN REINDUCTION MARVICH, MARIA 1634 §112Other Non-Final OA — Pending Dec 02, 2022
17921802 COMPOSITIONS AND METHODS OF PROMOTING MYELINATION TICHY, JENNIFER M.H. 1653 §103 Final Rejection — Pending Oct 27, 2022
17801238 METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING AN ALLERGY OR ANAPHYLAXIS BUNNER, BRIDGET E 1647 §101§102§112 Final Rejection — Pending Aug 19, 2022
17728927 THERAPEUTIC USES OF GENOME EDITING WITH CRISPR/Cas SYSTEMS WILSON, MICHAEL C 1638 §103§112 Non-Final OA — Pending Apr 25, 2022
17767340 METHODS AND COMPOSITIONS FOR TREATING ATAXIA TELANGIECTASIA MCLEOD, AFRICA MHAIRIE 1635 §102§103§112Other Final Rejection 89d overdue Pending Apr 07, 2022
17764413 BCL11A GUIDE AND BASE EDITOR DELIVERY HUMPHRIES, NICHOLAS ADAM 1631 §103 Non-Final OA 89d overdue Pending Mar 28, 2022

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Frequently Asked Questions

How many pending USPTO office actions does The Children's Medical Center Corporation have?

The Children's Medical Center Corporation has 27 pending office actions as of October 2026, spread across 21 art units and 27 examiners.

Which USPTO examiner handles the most The Children's Medical Center Corporation applications?

Jagadishwar Rao Samala has the most, with 1 of The Children's Medical Center Corporation's pending office actions.

What technology area are The Children's Medical Center Corporation's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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