Prosecution Insights
Last updated: August 16, 2026

The Scripps Research Institute

22 pending office actions • 16 art units • 21 examiners • 0 of 22 (0%) have an AI response strategy ready • 23 patents granted in the last 365 days

Portfolio Summary

22
Total Pending OAs
17
Non-Final OAs
5
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 9 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

5
Overdue
0
Due this week
2
Due this month
0
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 9 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (5)Due ≤ 30 days (2)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

10
Hard (45%)
7
Medium (32%)
5
Easy (23%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other2 (9%)
§103 only3 (14%)
§102 only3 (14%)
§112 only3 (14%)
Double-patenting only2 (9%)
Double-patenting + other1 (5%)
Multi-statute (no §101)8 (36%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

20
Life Sciences
91% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
2
Business / Other
9% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

220 h
Manual time on pending OAs
44 h
Time saved (low, 20%)
77 h
Time saved (mid, 35%)
1.9 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
DRISCOLL, LORA E BARNHART 2 31.7% +20.3%
SULLIVAN, STEPHANIE LAUREN 1 58.6% +39.6%
NEAGU, IRINA 1 46.8% +57.4%
ROBINSON, MIKHAIL O'DONNEL 1 58.9% +41.5%
LEE, ANDREW P 1 48.4% +23.3%
GILL, RACHEL B 1 65.4% +28.0%
CHANDRAKUMAR, NIZAL S 1 72.7% +18.3%
SABILA, MERCY HELLEN 1 57.6% +45.9%
KELLY, ROBERT M 1 73.8% +24.8%
MCCORMICK, CATHERINE LYNN 1 48.8% +35.6%

Hard Cases (10)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18327110 ENGINEERED CELLS AND METHODS OF USE KELLY, ROBERT M 2d overdue
18021792 ENGINEERED ARENAVIRUS GLYCOPROTEIN COMPOSITIONS AND METHODS OF USE THEREOF GILL, RACHEL B 20d
17768896 EFFICIENT RNA SWITCHES AND RELATED EXPRESSION SYSTEMS YAMASAKI, ROBERT J 22d
17923171 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 SCHACHERMEYER, SAMANTHA LYNN 65d
18388023 METHODS FOR MITIGATING AND PREVENTING PROTEOSTASIS-BASED INJURIES LEE, ANDREW P 83d
18517049 PHARMACOLOGICAL DEPLETION OF HEME FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME NEAGU, IRINA
18548635 HETEROBIFUNCTIONAL COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION AND METHODS FOR THEIR USE CHANDRAKUMAR, NIZAL S
18546750 SELECTIVE NEUTRAL PH INHIBITOR OF CATHEPSIN B SABILA, MERCY HELLEN

Interview Candidates (11)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18504724 HETEROARYL DIAMIDE IRE1/XBP1s ACTIVATORS ROBINSON, MIKHAIL O'DONNEL 26d overdue
18327110 ENGINEERED CELLS AND METHODS OF USE KELLY, ROBERT M 2d overdue
18021792 ENGINEERED ARENAVIRUS GLYCOPROTEIN COMPOSITIONS AND METHODS OF USE THEREOF GILL, RACHEL B 20d
18388023 METHODS FOR MITIGATING AND PREVENTING PROTEOSTASIS-BASED INJURIES LEE, ANDREW P 83d
19083131 REENGINEERING MRNA PRIMARY STRUCTURE FOR ENHANCED PROTEIN PRODUCTION DRISCOLL, LORA E BARNHART
18810305 REENGINEERING MRNA PRIMARY STRUCTURE FOR ENHANCED PROTEIN PRODUCTION DRISCOLL, LORA E BARNHART
18532609 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS SULLIVAN, STEPHANIE LAUREN
18517049 PHARMACOLOGICAL DEPLETION OF HEME FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME NEAGU, IRINA

Top Art Units

Art UnitApps
1627 3
3991 2
1654 2
1638 2
1699 2
1637 1
1629 1
1691 1
1671 1
1625 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19083131 REENGINEERING MRNA PRIMARY STRUCTURE FOR ENHANCED PROTEIN PRODUCTION DRISCOLL, LORA E BARNHART 3991 DP Non-Final OA Pending Mar 18, 2025
18810305 REENGINEERING MRNA PRIMARY STRUCTURE FOR ENHANCED PROTEIN PRODUCTION DRISCOLL, LORA E BARNHART 3991 DP Non-Final OA Pending Aug 20, 2024
18532609 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS SULLIVAN, STEPHANIE LAUREN 1637 §103§112DP Non-Final OA Pending Dec 07, 2023
18517049 PHARMACOLOGICAL DEPLETION OF HEME FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME NEAGU, IRINA 1629 §102§103 Non-Final OA Pending Nov 22, 2023
18504724 HETEROARYL DIAMIDE IRE1/XBP1s ACTIVATORS ROBINSON, MIKHAIL O'DONNEL 1627 §102 Non-Final OA 26d overdue Pending Nov 08, 2023
18388023 METHODS FOR MITIGATING AND PREVENTING PROTEOSTASIS-BASED INJURIES LEE, ANDREW P 1691 §102§103 Non-Final OA 83d Pending Nov 08, 2023
18021792 ENGINEERED ARENAVIRUS GLYCOPROTEIN COMPOSITIONS AND METHODS OF USE THEREOF GILL, RACHEL B 1671 §101§102§112Other Non-Final OA 20d Pending Oct 10, 2023
18548635 HETEROBIFUNCTIONAL COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION AND METHODS FOR THEIR USE CHANDRAKUMAR, NIZAL S 1625 §103§112 Final Rejection Pending Sep 01, 2023
18546750 SELECTIVE NEUTRAL PH INHIBITOR OF CATHEPSIN B SABILA, MERCY HELLEN 1654 §103§112 Non-Final OA Pending Aug 16, 2023
18327110 ENGINEERED CELLS AND METHODS OF USE KELLY, ROBERT M 1638 §102§112Other Non-Final OA 2d overdue Pending Jun 01, 2023
18315383 SONOGENETIC STIMULATION OF CELLS EXPRESSING A HETEROLOGOUS MECHANOSENSITIVE PROTEIN MCCORMICK, CATHERINE LYNN 1638 §103 Non-Final OA Pending May 10, 2023
18305292 COILED COIL IMMUNOGLOBULIN FUSION PROTEINS AND COMPOSITIONS THEREOF NATARAJAN, MEERA 1643 §102 Non-Final OA Pending Apr 21, 2023
18304993 REVERSE TRANSCRIPTION OF POLYNUCLEOTIDES COMPRISING UNNATURAL NUCLEOTIDES FLINDERS, JEREMY C 1684 §112 Final Rejection 10d overdue Pending Apr 21, 2023
18044260 SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS JARRELL, NOBLE E 1699 §101§102§112 Non-Final OA Pending Mar 07, 2023
17923171 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 SCHACHERMEYER, SAMANTHA LYNN 1693 §102§103 Non-Final OA 65d Pending Nov 03, 2022
17918448 GUANIDINE-MODIFIED C-TERMINUS VANCOMYCIN COMPOUNDS, COMPOSITIONS AND METHODS REYNOLDS, FRED H 1658 §103Other Final Rejection 30d overdue Pending Oct 12, 2022
17915559 SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ STOCKTON, LAURA LYNNE 1626 §102§112 Non-Final OA Pending Sep 29, 2022
17782560 GLP2 RECEPTOR AGONISTS AND METHODS OF USE HA, JULIE 1654 §112 Non-Final OA Pending Jun 03, 2022
17826660 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF OTTON, ALICIA L 1699 §102 Final Rejection Pending May 27, 2022
17768896 EFFICIENT RNA SWITCHES AND RELATED EXPRESSION SYSTEMS YAMASAKI, ROBERT J 1657 §103§112 Non-Final OA 22d Pending Apr 14, 2022
17753139 BICYCLIC AGONISTS OF STIMULATOR OF INTERFERON GENES STING HSU, GRACE CHING 1627 §112 Non-Final OA Pending Feb 21, 2022
17419904 THERAPEUTIC COMBINATIONS AS ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE IVANOVA, SVETLANA M 1627 §103 Final Rejection 11d overdue Pending Jun 30, 2021

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