Prosecution Insights
Last updated: August 18, 2026

Translate Bio Inc.

15 pending office actions • 11 art units • 12 examiners • 0 of 15 (0%) have an AI response strategy ready • 27 patents granted in the last 365 days

Portfolio Summary

15
Total Pending OAs
11
Non-Final OAs
4
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 6 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
1
Due this month
1
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 6 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 30 days (1)Due ≤ 60 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

3
Hard (20%)
7
Medium (47%)
4
Easy (27%)
1
Unknown (7%)

Rejection Statute Mix

BucketCases
§103 only5 (33%)
§102 only1 (7%)
§112 only2 (13%)
Double-patenting only2 (13%)
Double-patenting + other1 (7%)
Multi-statute (no §101)3 (20%)
No statute on record1 (7%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

14
Life Sciences
93% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
7% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

150 h
Manual time on pending OAs
30 h
Time saved (low, 20%)
52 h
Time saved (mid, 35%)
1.3 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
POPA, ILEANA 4 21.4% +14.6%
CABRAL, ROBERT S 1 62.6% +32.4%
GROOMS, TIFFANY NICOLE 1 58.8% +46.8%
ZARA, JANE J 1 70.9% +16.1%
MOORE, JOHN DAVID 1 65.4% +23.5%
ANDERSON, REBECCA L 1 73.3% +23.8%
SINGH, ANOOP KUMAR 1 42.8% +67.4%
BRANDSEN, BENJAMIN MICHAEL 1 60.4% +18.3%
MITCHELL, EDWIN COLEMAN 1 30.5% +64.9%
LU, FRANK WEI MIN 1 62.6% +67.6%

Hard Cases (7)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 7 ordered by deadline are shown.

App #TitleExaminerDue in
18431597 Liver Specific Delivery of Messenger RNA POPA, ILEANA 29d overdue
18334330 LIVER SPECIFIC DELIVERY OF MESSENGER RNA POPA, ILEANA 29d overdue
17450629 PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES POPA, ILEANA 9d
18890983 STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS POPA, ILEANA
18552165 Optimized Nucleotide Sequences Encoding the Extracellular Domain of Human ACE2 Protein or a Portion Thereof MOORE, JOHN DAVID
18186856 MRNA THERAPEUTIC COMPOSITIONS AND USE TO TREAT DISEASES AND DISORDERS SINGH, ANOOP KUMAR
17262421 Dry Powder Formulations for Messenger RNA HAGHIGHATIAN, MINA

Interview Candidates (13)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18431597 Liver Specific Delivery of Messenger RNA POPA, ILEANA 29d overdue
18334330 LIVER SPECIFIC DELIVERY OF MESSENGER RNA POPA, ILEANA 29d overdue
18246263 PIPERAZINE-BASED CATIONIC LIPIDS ANDERSON, REBECCA L 18d overdue
17450629 PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES POPA, ILEANA 9d
17534956 Stable Liquid Lipid Nanoparticle Formulations MITCHELL, EDWIN COLEMAN 47d
18890983 STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS POPA, ILEANA
18753746 PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES CABRAL, ROBERT S
18565849 ASSAY FOR QUANTITATIVE ASSESSMENT OF MRNA CAPPING EFFICIENCY GROOMS, TIFFANY NICOLE

Top Art Units

Art UnitApps
1633 3
1637 2
1614 1
1656 1
1626 1
1632 1
1693 1
1619 1
1683 1
1654 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18890983 STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS POPA, ILEANA §103 Non-Final OA Pending Sep 20, 2024
18753746 PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES CABRAL, ROBERT S 1614 §102 Non-Final OA Pending Jun 25, 2024
18431597 Liver Specific Delivery of Messenger RNA POPA, ILEANA 1633 Other Final Rejection 29d overdue Pending Feb 02, 2024
18565849 ASSAY FOR QUANTITATIVE ASSESSMENT OF MRNA CAPPING EFFICIENCY GROOMS, TIFFANY NICOLE 1637 §112 Non-Final OA Pending Nov 30, 2023
18286029 IMPROVED COMPOSITIONS FOR DELIVERY OF MRNA ZARA, JANE J 1637 DP Non-Final OA Pending Oct 06, 2023
18552165 Optimized Nucleotide Sequences Encoding the Extracellular Domain of Human ACE2 Protein or a Portion Thereof MOORE, JOHN DAVID 1656 §103§112 Non-Final OA Pending Sep 22, 2023
18334330 LIVER SPECIFIC DELIVERY OF MESSENGER RNA POPA, ILEANA 1633 §103Other Final Rejection 29d overdue Pending Jun 13, 2023
18246263 PIPERAZINE-BASED CATIONIC LIPIDS ANDERSON, REBECCA L 1626 DP Final Rejection 18d overdue Pending Mar 22, 2023
18186856 MRNA THERAPEUTIC COMPOSITIONS AND USE TO TREAT DISEASES AND DISORDERS SINGH, ANOOP KUMAR 1632 §103§112 Non-Final OA Pending Mar 20, 2023
17871121 METHODS FOR PURIFICATION OF MESSENGER RNA BRANDSEN, BENJAMIN MICHAEL 1693 §103Other Final Rejection Pending Jul 22, 2022
17534956 Stable Liquid Lipid Nanoparticle Formulations MITCHELL, EDWIN COLEMAN 1619 §103Other Non-Final OA 47d Pending Nov 24, 2021
17450629 PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES POPA, ILEANA 1633 §103Other Non-Final OA 9d Pending Oct 12, 2021
17344535 METHODS FOR PURIFICATION OF MESSENGER RNA LU, FRANK WEI MIN 1683 §103§112DP Non-Final OA Pending Jun 10, 2021
17291937 2,5-DIOXOPIPERAZINE LIPIDS WITH INTERCALATED ESTER, THIOESTER, DISULFIDE AND ANHYDRIDE MOIEITIES AUDET, MAURY A 1654 §112 Non-Final OA 79d Pending May 06, 2021
17262421 Dry Powder Formulations for Messenger RNA HAGHIGHATIAN, MINA 1616 §103§112 Non-Final OA Pending Jan 22, 2021

Managing Translate Bio Inc.'s Patent Portfolio?

IP Author helps IP teams respond to office actions faster with AI-generated responses, examiner analytics, and prosecution intelligence.

Start Free Trial

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month