Prosecution Insights
Last updated: May 29, 2026

Translate Bio, Inc.

14 pending office actions • 9 art units • 11 examiners • 0 of 14 (0%) have an AI response strategy ready • 24 patents granted in the last 365 days

Portfolio Summary

14
Total Pending OAs
7
Non-Final OAs
7
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 14 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

8
Overdue
1
Due this week
2
Due this month
2
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 14 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (8)Due ≤ 7 days (1)Due ≤ 30 days (2)Due ≤ 60 days (2)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
5
Medium (36%)
2
Easy (14%)
7
Unknown (50%)

Rejection Statute Mix

BucketCases
§103 only5 (36%)
§112 only2 (14%)
No statute on record7 (50%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

14
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

140 h
Manual time on pending OAs
28 h
Time saved (low, 20%)
49 h
Time saved (mid, 35%)
1.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
POPA, ILEANA 3 21.0% +14.9%
MITCHELL, EDWIN COLEMAN 2 33.3% +65.1%
RONEY, CELESTE A 1 62.3% +18.0%
SHOMER, ISAAC 1 63.1% +30.7%
ANDERSON, REBECCA L 1 73.2% +24.0%
NGUYEN, QUANG 1 38.2% +52.8%
BURKHART, MICHAEL D 1 62.4% +10.9%
AUDET, MAURY A 1 50.0% +23.7%
POHNERT, STEVEN C 1 12.1% +18.3%
ARIETI, RUTH SOPHIA 1 45.2% +73.6%

Hard Cases (4)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
17172527 METHODS AND COMPOSITIONS FOR MESSENGER RNA PURIFICATION POHNERT, STEVEN C 96d overdue
18431597 Liver Specific Delivery of Messenger RNA POPA, ILEANA 29d overdue
18334330 LIVER SPECIFIC DELIVERY OF MESSENGER RNA POPA, ILEANA 29d overdue
17450629 PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES POPA, ILEANA 9d

Interview Candidates (13)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17292923 METHODS FOR INDUCING IMMUNE TOLERANCE BURKHART, MICHAEL D 252d overdue
17592335 MRNA THERAPY FOR THE TREATMENT OF OCULAR DISEASES NGUYEN, QUANG 238d overdue
17172527 METHODS AND COMPOSITIONS FOR MESSENGER RNA PURIFICATION POHNERT, STEVEN C 96d overdue
18431597 Liver Specific Delivery of Messenger RNA POPA, ILEANA 29d overdue
18334330 LIVER SPECIFIC DELIVERY OF MESSENGER RNA POPA, ILEANA 29d overdue
18575019 COMPOSITIONS FOR DELIVERY OF MRNA RONEY, CELESTE A 22d overdue
18246263 PIPERAZINE-BASED CATIONIC LIPIDS ANDERSON, REBECCA L 18d overdue
17055251 Subcutaneous Delivery of Messenger RNA ARIETI, RUTH SOPHIA 5d

Top Art Units

Art UnitApps
1633 3
1612 2
1619 2
1635 2
1626 1
1631 1
1638 1
1654 1
1683 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18431597 Liver Specific Delivery of Messenger RNA POPA, ILEANA 1633 Other Final Rejection 29d overdue Pending Feb 02, 2024
18575019 COMPOSITIONS FOR DELIVERY OF MRNA RONEY, CELESTE A 1612 Other Non-Final OA 22d overdue Pending Dec 28, 2023
18555439 "Good" buffer-based cationic lipids SHOMER, ISAAC 1612 Other Final Rejection 9d Pending Oct 13, 2023
18334330 LIVER SPECIFIC DELIVERY OF MESSENGER RNA POPA, ILEANA 1633 §103 Final Rejection 29d overdue Pending Jun 13, 2023
18246263 PIPERAZINE-BASED CATIONIC LIPIDS ANDERSON, REBECCA L 1626 Other Non-Final OA 18d overdue Pending Mar 22, 2023
17592335 MRNA THERAPY FOR THE TREATMENT OF OCULAR DISEASES NGUYEN, QUANG 1631 §103 Non-Final OA 238d overdue Pending Feb 03, 2022
17534956 Stable Liquid Lipid Nanoparticle Formulations MITCHELL, EDWIN COLEMAN 1619 Other Final Rejection 47d Pending Nov 24, 2021
17611020 IMPROVED PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES MITCHELL, EDWIN COLEMAN 1619 Other Non-Final OA 33d Pending Nov 12, 2021
17450629 PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES POPA, ILEANA 1633 §103 Final Rejection 9d Pending Oct 12, 2021
17292923 METHODS FOR INDUCING IMMUNE TOLERANCE BURKHART, MICHAEL D 1638 §112 Non-Final OA 252d overdue Pending May 11, 2021
17291937 2,5-DIOXOPIPERAZINE LIPIDS WITH INTERCALATED ESTER, THIOESTER, DISULFIDE AND ANHYDRIDE MOIEITIES AUDET, MAURY A 1654 §112 Non-Final OA 79d Pending May 06, 2021
17172527 METHODS AND COMPOSITIONS FOR MESSENGER RNA PURIFICATION POHNERT, STEVEN C 1683 §103 Non-Final OA 96d overdue Pending Feb 10, 2021
17055251 Subcutaneous Delivery of Messenger RNA ARIETI, RUTH SOPHIA 1635 Other Final Rejection 5d Pending Nov 13, 2020
17076195 COMPOSITIONS, METHODS AND USES OF MESSENGER RNA SHIN, DANA H 1635 §103 Final Rejection 71d overdue Pending Oct 21, 2020

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