Prosecution Insights
Last updated: October 02, 2026

Examiner: GROSS, CHRISTOPHER M

Tech Center 1600 • Art Units: 1612 1636 1639 1653 1675 1678 1682 1684

This examiner grants 64% of resolved cases

Analysis

Christopher M Gross is a senior examiner in Tech Center 1600, specifically Art Unit 1612, with 669 resolved cases. His allowance rate of 63.5 percent indicates a generally positive outlook for applicants, with a majority of cases reaching a grant. This large sample size provides a high degree of confidence in the examiner's prosecution patterns within the biotechnology and organic chemistry fields.

The interview lift of 40.2 percent is particularly striking, suggesting that oral advocacy is exceptionally effective with this examiner. This high lift indicates that an interview can dramatically increase the chances of an allowance, likely by resolving complex technical issues that are difficult to address solely through written correspondence. Practitioners should strongly consider scheduling interviews early in the process.

The median days to allowance is 1542, which is a significantly longer timeline than many other units. This duration of over four years suggests that while the eventual probability of grant is good, the process is likely to involve extensive examination and multiple office actions. Applicants should be prepared for a long-term engagement when their cases are assigned to Art Unit 1612.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

63.5%
Allow Rate
+3.5% vs TC avg
699
Total Applications
+40.2%
Interview Lift
1542
Avg Prosecution Days
Based on 669 resolved cases, 2023–2026

Rejection Statute Breakdown

3.9%
§101 Eligibility
29.3%
§102 Novelty
32.1%
§103 Obviousness
24.6%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
17182044 GENE EXPRESSION-BASED BIOMARKER FOR THE DETECTION AND MONITORING OF BRONCHIAL PREMALIGNANT LESIONS Non-Final OA Trustees of Boston University
18189056 COMBINATORIAL PLATFORM FOR HIGH-THROUGHPUT POLYNUCLEOTIDE-ENCODED CATALYST DISCOVERY Final Rejection WISCONSIN ALUMNI RESEARCH FOUNDATION
18051711 METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS Non-Final OA Ohio State Innovation Foundation
18291773 Methods and Compositions for Producing Cell-Source Identifiable Collections of Nucleic Acids Non-Final OA Takara Bio USA, Inc.
18408191 SYSTEM FOR THE DIRECTED EVOLUTION OF BIOMOLECULES IN MULTI-BODY COMPLEXES Non-Final OA Massachusetts Institute of Technology
18396156 Digital Analysis of Circulating Tumor Cells in Blood Samples Final Rejection The General Hospital Corporation
18702311 PRE-LIBRARY TARGET ENRICHMENT FOR NUCLEIC ACID SEQUENCING Non-Final OA University of Utah Research Foundation
18253250 TARGETING HOST-BACTERIA INTERACTIONS FOR THE TREATMENT OF MICROBIOTA-MEDIATED DISEASES Non-Final OA YALE UNIVERSITY
18230872 TESTING COLON CANCER DRUGS FOR IMMUNOMODULATORY EFFECTS Non-Final OA BROWN UNIVERSITY
18580463 SCREENING CODON-OPTIMIZED NUCLEOTIDE SEQUENCES Non-Final OA TRANSLATE BIO, INC.
18025100 ARRAY, SOAKING SOLUTIONS AND METHOD OF SELECTING SOAKING CONDITIONS FOR SMALL MOLECULES IN BIOLOGICAL MACROMOLECULAR CRYSTALS Final Rejection CRYSTALSFIRST GMBH
18025103 ARRAY, SOAKING SOLUTIONS AND METHOD OF SELECTING SOAKING CONDITIONS FOR SMALL MOLECULES IN BIOLOGICAL MACROMOLECULAR CRYSTALS Final Rejection CRYSTALSFIRST GMBH
18025107 ARRAY, SOAKING SOLUTIONS AND METHOD OF SELECTING SOAKING CONDITIONS FOR SMALL MOLECULES IN BIOLOGICAL MACROMOLECULAR CRYSTALS Final Rejection CRYSTALSFIRST GMBH
17702643 VARIANT NUCLEIC ACID LIBRARIES FOR TIGIT Final Rejection Twist Bioscience Corporation

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