Prosecution Insights
Last updated: October 04, 2026

University of Louisville Research Foundation Inc.

Technology areas: Biotechnology & Pharmaceuticals • Chemistry & Materials

29 pending office actions • 21 art units • 26 examiners • 0 of 29 (0%) have an AI response strategy ready • 21 patents granted in the last 365 days

Analysis

University of Louisville Research Foundation Inc. has 27 pending office actions in the Biotechnology & Pharmaceuticals technology area. These matters are spread across 24 distinct examiners and 19 distinct art units. This distribution reflects a diverse research output, with the 27 pending office actions touching on many different facets of biotechnology and pharmaceutical science. With 19 distinct art units in play, practitioners must adapt to a range of examiner preferences and art unit policies across the portfolio.

MERRIAM, AARON ROGERS is the busiest examiner, overseeing 2 pending office actions. The fact that 24 distinct examiners are involved for 27 actions indicates that most examiners are handling only a single case for the foundation. Such an array of examiners and units requires a coordinated strategy to ensure consistency in claim construction and legal arguments. The breadth of this activity reflects the foundation's investment in intellectual property, necessitating an approach to managing the various procedural requirements associated with 24 distinct examiners.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

29
Total Pending OAs
13
Non-Final OAs
15
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 12 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
1
Due this week
7
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 12 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 7 days (1)Due ≤ 30 days (7)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

15
Hard (52%)
12
Medium (41%)
1
Easy (3%)
1
Unknown (3%)

Rejection Statute Mix

BucketCases
§101 + other4 (14%)
§103 only9 (31%)
§102 only2 (7%)
§112 only1 (3%)
Double-patenting + other1 (3%)
Multi-statute (no §101)11 (38%)
No statute on record1 (3%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

22
Life Sciences
76% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
5
Mechanical / Eng
17% of docket
2
Business / Other
7% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

290 h
Manual time on pending OAs
58 h
Time saved (low, 20%)
102 h
Time saved (mid, 35%)
2.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
MERRIAM, AARON ROGERS 2 31.6% +63.1%
KIM, TAEYOON 2 51.5% +52.1%
WANG, RUIXUE 2 57.4% +17.8%
ZHU, JIANJIAN 1 58.8% +82.4%
KHANDKER, RAIHAN R 1 64.2% +57.2%
DIBRINO, MARIANNE 1 42.8% +42.2%
SHERMAN, ERIC SCOTT 1 73.5% +18.5%
MACHNESS, ARIELLA 1 61.9% +28.5%
MULLINS, JESSICA LYNN 1 49.5% +34.0%
SCHUBERG, LAURA J 1 23.6% +37.0%

Hard Cases (16)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17544279 ELECTROCHEMICAL ENERGY STORAGE DEVICES COMPRISING HALIDE-CONTAINING LITHIUM ARGYRODITE SOLID ELECTROLYTES ORTIZ, ARYANA YASMINE 117d overdue
17780961 BIOMASS-BASED SOLID COMPOSITE ELECTROLYTES FOR BATTERIES NGUYEN, KEVIN NMN 56d overdue
17641787 ANTI-NUCLEOLIN AGENT-PEG-CONJUGATED NANOPARTICLES MEJIAS, SAMANTHA LEE 3d overdue
18020235 METHODS AND COMPOSITIONS FOR TREATING PERIODONTAL DISEASE WEBB, WALTER E 6d
17862892 3-D BIOPRINTING COMPRISING BIOLOGICALLY-RELEVANT MATERIALS AND RELATED METHODS KIM, TAEYOON 12d
18274412 INHIBITION OF DEGRANULATION OF NEUTROPHIL CELLS IN COVID-19 PATIENTS BANERJEE, KOYELI 13d
18008391 IDENTIFICATION OF LOW-DENSITY INFLAMMATORY NEUTROPHILS IN SEVERE COVID-19 PATIENTS WANG, RUIXUE 20d
18230278 METHOD OF TREATMENT FOR HEART FAILURE USING STEM CELLS SCHUBERG, LAURA J 34d

Interview Candidates (13)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17862892 3-D BIOPRINTING COMPRISING BIOLOGICALLY-RELEVANT MATERIALS AND RELATED METHODS KIM, TAEYOON 12d
18008391 IDENTIFICATION OF LOW-DENSITY INFLAMMATORY NEUTROPHILS IN SEVERE COVID-19 PATIENTS WANG, RUIXUE 20d
18233416 IN-PROCESS ULTRASONIC POLLING OF 3D PRINTED CRYSTALLINE/SEMICRYSTALLINE ELECTROACTIVE POLYMERS MACHNESS, ARIELLA 29d
18124656 HUMAN FACILITATING CELLS KIM, TAEYOON 29d
18230278 METHOD OF TREATMENT FOR HEART FAILURE USING STEM CELLS SCHUBERG, LAURA J 34d
18981938 PHYSIOLOGICAL BIOMIMETIC CULTURE SYSTEM FOR HEART SLICES ZHU, JIANJIAN —
18551043 LEFT ATRIAL APPENDAGE CLOSURE DEVICE WITH CATHETER-BASED DELIVERY KHANDKER, RAIHAN R —
18277684 Actinohivin Variant Polypeptides and Related Methods DIBRINO, MARIANNE —

Top Art Units

Art UnitApps
1631 3
1641 2
3791 2
1672 2
1618 2
3771 1
1736 1
1743 1
3796 1
1658 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18981938 PHYSIOLOGICAL BIOMIMETIC CULTURE SYSTEM FOR HEART SLICES ZHU, JIANJIAN — §103 Non-Final OA — Pending Dec 16, 2024
18551043 LEFT ATRIAL APPENDAGE CLOSURE DEVICE WITH CATHETER-BASED DELIVERY KHANDKER, RAIHAN R 3771 §103 Final Rejection — Pending Sep 18, 2023
18277684 Actinohivin Variant Polypeptides and Related Methods DIBRINO, MARIANNE 1641 §103§112DP Final Rejection — Pending Aug 17, 2023
18450060 ULTRATHIN NANORIBBONS OF HIGHLY ANISOTROPIC LAYERED MATERIAL AND METHOD OF PRODUCTION SHERMAN, ERIC SCOTT 1736 §102 Non-Final OA — Pending Aug 15, 2023
18233416 IN-PROCESS ULTRASONIC POLLING OF 3D PRINTED CRYSTALLINE/SEMICRYSTALLINE ELECTROACTIVE POLYMERS MACHNESS, ARIELLA 1743 §103 Final Rejection 29d Pending Aug 14, 2023
18447661 SYSTEMS AND METHODS FOR IMPROVING MULTIPLE PHYSIOLOGICAL FUNCTIONS USING NEUROSTIMULATION MULLINS, JESSICA LYNN 3796 §102 Non-Final OA — Pending Aug 10, 2023
18230278 METHOD OF TREATMENT FOR HEART FAILURE USING STEM CELLS SCHUBERG, LAURA J 1631 §103 Final Rejection 34d Pending Aug 04, 2023
18274412 INHIBITION OF DEGRANULATION OF NEUTROPHIL CELLS IN COVID-19 PATIENTS BANERJEE, KOYELI 1658 §103§112 Final Rejection 13d Pending Jul 26, 2023
18261950 ACTINOHIVIN VARIANT POLYPEPTIDES AND RELATED METHODS ALFANO, ALAN 1641 §101§102§103§112DP Non-Final OA — Pending Jul 18, 2023
18333400 METHOD OF INHIBITING LUNG OR BREAST CANCER GROWTH WITH ENGINEERED EMBRYONIC STEM-CELL DERIVED EXOSOMES COMPOSITIONS STOICA, ELLY GERALD 1647 §103 Non-Final OA — Pending Jun 12, 2023
18253780 METHODS FOR OPTIMIZATION OF PLACEMENT OF SPINAL CORD EPIDURAL STIMULATION UNIT THOMAS, SOUMYA — §101§103 Non-Final OA — Pending May 20, 2023
18307512 SYSTEMS AND METHODS TO MEASURE AND IMPROVE EYE MOVEMENTS AND FIXATION MERRIAM, AARON ROGERS 3791 §103§112 Final Rejection — Pending Apr 26, 2023
18248491 PROBIOTIC DELIVERY SYSTEMS AND METHODS OF MAKING AND USING HINES, JANA A 1645 §103 Non-Final OA 29d Pending Apr 10, 2023
18030174 GRIFFITHSIN FOR RHABDOVIRIDAE INFECTIONS DABKOWSKI, ERINNE R 1654 §103 Final Rejection 14d Pending Apr 04, 2023
18124656 HUMAN FACILITATING CELLS KIM, TAEYOON 1631 Other Final Rejection 29d Pending Mar 22, 2023
18020235 METHODS AND COMPOSITIONS FOR TREATING PERIODONTAL DISEASE WEBB, WALTER E 1612 §102§103§112 Non-Final OA 6d Pending Feb 07, 2023
18162777 CELL LINES, SYSTEMS, KITS, AND METHODS FOR DETERMINING THE SPECIFICITY AND/OR POTENCY OF CERAMIDASE INHIBITORS TICHY, JENNIFER M.H. 1637 §103§112 Non-Final OA — Pending Feb 01, 2023
18013010 FIBER PRETREATMENT FOR IMPROVED NATURAL FIBER - POLYMER COMPOSITE FEEDSTOCK PRODUCTION EASHOO, MARK 1767 §103§112 Non-Final OA — Pending Dec 27, 2022
18008391 IDENTIFICATION OF LOW-DENSITY INFLAMMATORY NEUTROPHILS IN SEVERE COVID-19 PATIENTS WANG, RUIXUE 1672 §101§102§112 Non-Final OA 20d Pending Dec 05, 2022
17997764 BIOMIMETIC HEART TISSUE CULTURE SYSTEM HENKEL, DANIELLE B 1799 §103§112 Non-Final OA — Pending Nov 02, 2022
17913575 METHODS AND COMPOSITIONS FOR DETECTING VIRUSES WANG, RUIXUE 1672 §103 Final Rejection — Pending Sep 22, 2022
17862892 3-D BIOPRINTING COMPRISING BIOLOGICALLY-RELEVANT MATERIALS AND RELATED METHODS KIM, TAEYOON 1631 §103§112Other Final Rejection 12d Pending Jul 12, 2022
17780961 BIOMASS-BASED SOLID COMPOSITE ELECTROLYTES FOR BATTERIES NGUYEN, KEVIN NMN 1752 §103§112 Non-Final OA 56d overdue Pending May 27, 2022
17741686 ANTI-NUCLEOLIN AGENT-CONJUGATED NANOPARTICLES JONES, DAMERON LEVEST 1618 §102§112Other Final Rejection — Pending May 11, 2022
17641787 ANTI-NUCLEOLIN AGENT-PEG-CONJUGATED NANOPARTICLES MEJIAS, SAMANTHA LEE 1618 §102§103§112Other Final Rejection 3d overdue Pending Mar 09, 2022
17639825 SYSTEMS AND METHODS FOR DETECTION AND GRADING OF DIABETIC RETINOPATHY MERRIAM, AARON ROGERS 3791 §101§103 Final Rejection — Pending Mar 02, 2022
17629309 IMMUNOMODULATORY COMPOSITIONS AND METHODS OF USING HILL, MYRON G 1671 §112 Final Rejection — Pending Jan 21, 2022
17544279 ELECTROCHEMICAL ENERGY STORAGE DEVICES COMPRISING HALIDE-CONTAINING LITHIUM ARGYRODITE SOLID ELECTROLYTES ORTIZ, ARYANA YASMINE 1751 §103§112 Final Rejection 117d overdue Pending Dec 07, 2021
16789572 MODULAR HARNESS FOR PATIENTS WITH POST-NEUROLOGIC INJURY MILLER, CHRISTOPHER E 3785 §103 Non-Final OA — Pending Feb 13, 2020

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