Technology area: Biotechnology & Pharmaceuticals
68 pending office actions • 38 art units • 60 examiners • 0 of 68 (0%) have an AI response strategy ready • 80 patents granted in the last 365 days
University of Massachusetts has 70 pending office actions in Biotechnology & Pharmaceuticals. The matters span 61 distinct examiners and 38 distinct art units, creating a distributed portfolio with multiple technical examination environments.
LEONARD, ARTHUR S is the busiest examiner, with 4 pending matters. That assignment is only one segment of the stated workload. Counsel should use centralized docket management to preserve consistency while tracking examiner-specific practices and art-unit issues separately.
Based on the USPTO statutory response window for each pending office action. 22 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 22 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 + other | 1 (1%) |
| §103 only | 18 (26%) |
| §112 only | 5 (7%) |
| Double-patenting + other | 6 (9%) |
| Multi-statute (no §101) | 37 (54%) |
| No statute on record | 1 (1%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| LEONARD, ARTHUR S | 4 | 50.5% | +50.4% |
| ABBOTT, KODYE LEE | 2 | 54.5% | +71.4% |
| VANHORN, ABIGAIL LOUISE | 2 | 46.8% | +22.7% |
| WHITEMAN, BRIAN A | 2 | 68.4% | +16.8% |
| MEYERING, SHABANA SHABBEER | 2 | 68.5% | +45.1% |
| KONOPKA, CATHERINE ANNE | 2 | 57.5% | +66.2% |
| POLLEY, CHRISTOPHER M | 1 | 73.0% | +26.2% |
| SALVOZA, M FRANCO G | 1 | 68.2% | +30.6% |
| COLLISTER, ELIZABETH A | 1 | 81.7% | +14.1% |
| NAH, JONGBONG | 1 | 76.0% | +17.5% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18065255 | SILENCING OF DUX4 BY RECOMBINANT GENE EDITING COMPLEXES | NICOL, ALEXANDER W | 79d overdue |
| 18247157 | MARF/MFN MODULATORS AND USES THEREOF | GROOMS, TIFFANY NICOLE | 37d overdue |
| 18049724 | COMPLEXES FOR GENE DELETION AND EDITING | LEONARD, ARTHUR S | 11d overdue |
| 17777363 | COMPOSITIONS AND METHODS FOR OPTOGENETIC IMMUNOTHERAPY | HAMA, JOANNE | 5d overdue |
| 18120030 | OLIGONUCLEOTIDES FOR APP MODULATION | ALLEN, SARAH ELIZABETH | 2d overdue |
| 18081604 | NANODEVICES AND METHODS FOR MEASURING BIOFLUIDIC FLOW USING A GRAPHENE-BASED MICROELECTRODE | MONTGOMERY, MELISSA JO | 9d |
| 18489422 | ENCAPSULATING ELECTRONICS ON FLEXIBLE FLUOROELASTOMER SUBSTRATES | CARLEY, JEFFREY T. | 13d |
| 18094695 | OLIGONUCLEOTIDES FOR MECP2 MODULATION | DACE DENITO, ALEXANDRA GERALDINE | 22d |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18980456 | Targeted CRISPR Delivery Platforms | LEONARD, ARTHUR S | 50d overdue |
| 18049724 | COMPLEXES FOR GENE DELETION AND EDITING | LEONARD, ARTHUR S | 11d overdue |
| 17913100 | MICRORNAS FOR THE PREVENTION OF CLINICAL VENOUS THROMBOEMBOLIC DISEASE | WHITEMAN, BRIAN A | 8d |
| 19217607 | VECTOR-BASED GENE THERAPY FOR ELONGATOR ACETYLTRANSFERASE COMPLEX SUBUNIT 1 (ELP1) | SALVOZA, M FRANCO G | 57d |
| 19637632 | CIRCULAR RNA VECTORS COMPRISING MODIFIED NUCLEOTIDES | ABBOTT, KODYE LEE | — |
| 19568680 | YEAST CELL WALL PARTICLE ENCAPSULATION OF BIODEGRADABLE PRO-PAYLOADS | VANHORN, ABIGAIL LOUISE | — |
| 19228243 | PATTERNED NANOPARTICLE STRUCTURES | POLLEY, CHRISTOPHER M | — |
| 19102366 | VACUUM-INSULATED STRUCTURES EMPLOYING PLANT MATERIALS, AND METHODS FOR FABRICATION AND USE THEREOF | COLLISTER, ELIZABETH A | — |
| Art Unit | Apps |
|---|---|
| 1635 | 8 |
| 1636 | 7 |
| 1634 | 5 |
| 1631 | 5 |
| 1637 | 5 |
| 1785 | 2 |
| 1672 | 2 |
| 1645 | 2 |
| 1656 | 2 |
| 1632 | 2 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19637632 | CIRCULAR RNA VECTORS COMPRISING MODIFIED NUCLEOTIDES | ABBOTT, KODYE LEE | 1634 | §102§103§112 | Non-Final OA | — | Pending | Apr 02, 2026 |
| 19568680 | YEAST CELL WALL PARTICLE ENCAPSULATION OF BIODEGRADABLE PRO-PAYLOADS | VANHORN, ABIGAIL LOUISE | 1636 | §103§112DP | Non-Final OA | — | Pending | Mar 16, 2026 |
| 19228243 | PATTERNED NANOPARTICLE STRUCTURES | POLLEY, CHRISTOPHER M | 1785 | Other | Non-Final OA | — | Pending | Jun 04, 2025 |
| 19217607 | VECTOR-BASED GENE THERAPY FOR ELONGATOR ACETYLTRANSFERASE COMPLEX SUBUNIT 1 (ELP1) | SALVOZA, M FRANCO G | 1672 | §112 | Non-Final OA | 57d | Pending | May 23, 2025 |
| 19102366 | VACUUM-INSULATED STRUCTURES EMPLOYING PLANT MATERIALS, AND METHODS FOR FABRICATION AND USE THEREOF | COLLISTER, ELIZABETH A | 1784 | §102§103 | Non-Final OA | — | Pending | Feb 07, 2025 |
| 18980456 | Targeted CRISPR Delivery Platforms | LEONARD, ARTHUR S | 1631 | §112DP | Non-Final OA | 50d overdue | Pending | Dec 13, 2024 |
| 18869129 | METHODS AND SYSTEMS FOR IMAGING INTERACTIONS BETWEEN PARTICLES AND FRAGMENTS | NAH, JONGBONG | 2674 | §103 | Non-Final OA | — | Pending | Nov 25, 2024 |
| 18851628 | ANTIGEN DELIVERING SALMONELLA FOR USE AS A TUMOR HOMING BEACON TO REFOCUS PREEXISTING, VACCINE GENERATED T CELLS TO COMBAT CANCER | GRASER, JENNIFER E | 1645 | §103§112 | Non-Final OA | — | Pending | Sep 26, 2024 |
| 18807414 | PATTERNING OF COMPLEX METAL OXIDE STRUCTURES | VONCH, JEFFREY A | 1781 | §102§103 | Non-Final OA | — | Pending | Aug 16, 2024 |
| 18762831 | METHOD FOR ELECTROCHEMICAL TREATMENT OF WATER | MENDOZA, WILSON GALLARDO | 1772 | §103§112Other | Non-Final OA | — | Pending | Jul 03, 2024 |
| 18721049 | FORMULATIONS FOR FORMING A STRUCTURED NANOPARTICLE COMPOSITE | ROSWELL, JESSICA MARIE | 1767 | §102§103§112 | Non-Final OA | — | Pending | Jun 17, 2024 |
| 18743008 | ACTIVATABLE NANOREPORTERS FOR REAL-TIME TRACKING OF MACROPHAGE PHENOTYPIC STATES ASSOCIATED WITH DISEASE PROGRESSION | NOAKES, SUZANNE MARIE | 1656 | §102§112 | Non-Final OA | — | Pending | Jun 13, 2024 |
| 18719340 | CONSTITUTIVE PRODUCTION OF MICROCINS TO TARGET ENTERIC BACTERIA | RIGA, MICHAEL ANGELO | 1634 | §102§103§112 | Non-Final OA | — | Pending | Jun 13, 2024 |
| 18671475 | ARTICLE COMPRISING NON-WELDABLE SUPERALLOYS AND METHODS OF MANUFACTURE THEREOF | SULTANA, NAHIDA | 1785 | §102§112 | Non-Final OA | — | Pending | May 22, 2024 |
| 18660623 | INTRAVENOUS POLE FOR IMPROVED SAFETY AND ACCURACY OF INTRAVENOUS MEDICATION ADMINISTRATION | SOLOMON, JOSHUA BRENDON | 3792 | §103 | Final Rejection | — | Pending | May 10, 2024 |
| 18707207 | WNT-MODULATING GENE SILENCERS AS BONE ANABOLIC THERAPY FOR OSTEOPOROSIS AND CRITICAL-SIZED BONE DEFECT | VISONE, THOMAS J | 1672 | §103§112 | Non-Final OA | — | Pending | May 03, 2024 |
| 18706551 | USES OF RHODOQUINONE FOR THE TREATMENT OF DISEASE | BRAUN, MADELINE E | 1624 | §102§103§112 | Non-Final OA | — | Pending | May 01, 2024 |
| 18705007 | A Subunit Cryptococcus Vaccine | OGUNBIYI, OLUWATOSIN A | 1645 | §102§112 | Non-Final OA | — | Pending | Apr 26, 2024 |
| 18625271 | HIGH THROUGHPUT LOCALIZED PASSIVE DIFFUSION DEVICE FOR PATTERNING ORGANOIDS | ABBOTT, KODYE LEE | 1634 | §103 | Non-Final OA | — | Pending | Apr 03, 2024 |
| 18612111 | Targeted CRISPR Delivery Platforms | LEONARD, ARTHUR S | 1631 | §103§112DP | Non-Final OA | — | Pending | Mar 21, 2024 |
| 18688729 | AMPLIFIABLE METABOLIC LABELING FOR DETECTION OF BACTERIAL VIABILITY, GROWTH AND ANTIBIOTIC SUSCEPTIBILITY | FAN, WEIHUA | 1663 | §103 | Final Rejection | 18d overdue | Pending | Mar 01, 2024 |
| 18582916 | COMPACT MICRORING SCHEME FOR CHIP LASER INJECTION LOCKING AND OPTICAL PARAMETRIC OSCILLATION | LEUNG, CHRISTINA Y | 3991 | §103§112Other | Non-Final OA | — | Pending | Feb 21, 2024 |
| 18439034 | STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLEX USING ALKYLATED PHOSPHATE | MCINTOSH III, TRAVISS C | 1693 | §102§112 | Non-Final OA | — | Pending | Feb 12, 2024 |
| 18421647 | MODIFIED OLIGONUCLEOTIDES TARGETING SNPs | WHITEMAN, BRIAN A | 1636 | §102§103§112DP | Non-Final OA | — | Pending | Jan 24, 2024 |
| 18577623 | MODULAR PRIME EDITING SYSTEMS FOR GENOME ENGINEERING | WARD, AARON DUREL | 1636 | §102§112 | Non-Final OA | — | Pending | Jan 08, 2024 |
| 18396613 | BRANCHED OLIGONUCLEOTIDES | ZARA, JANE J | 1635 | §103§112DP | Non-Final OA | — | Pending | Dec 26, 2023 |
| 18561036 | APPARATUS AND METHOD FOR CONTINUOUS PRODUCTION OF RNA | MEYERING, SHABANA SHABBEER | 1635 | §103 | Final Rejection | — | Pending | Nov 15, 2023 |
| 18509212 | Articles Formed From Fluorine-Containing Elastomer Compositions Using Additive Manufacturing Methods and Additive Manufacturing Methods for Thermoset Elastomer Compositions | AHMED ALI, MOHAMED K | 1743 | §103 | Non-Final OA | — | Pending | Nov 14, 2023 |
| 18288786 | ERGONOMIC SURGICAL INSTRUMENTS | MENDEZ, KATHERINE H | 3771 | §102§103§112 | Non-Final OA | — | Pending | Oct 27, 2023 |
| 18288225 | GENE THERAPIES FOR STARGARDT DISEASE (ABCA4) | HUDSON, AMY ROSE | 1636 | §102§103§112 | Non-Final OA | — | Pending | Oct 25, 2023 |
| 18489422 | ENCAPSULATING ELECTRONICS ON FLEXIBLE FLUOROELASTOMER SUBSTRATES | CARLEY, JEFFREY T. | 3729 | §102§103 | Final Rejection | 13d | Pending | Oct 18, 2023 |
| 18380871 | CONJUGATES OF SIRNA AND ANTISENSE OLIGONUCLEOTIDES (SIRNASO) AND METHODS OF USE IN GENE SILENCING | POLIAKOVA-GEORGAN, EKATERINA | 1637 | §102§103§112 | Non-Final OA | — | Pending | Oct 17, 2023 |
| 18287056 | APPARATUS FOR ELECTROCHEMICAL AMMUNITION DISPOSAL AND MATERIAL RECOVERY | CHUNG, HOSUNG CHARLES | 1794 | §103§112 | Non-Final OA | — | Pending | Oct 16, 2023 |
| 18482052 | NANOPORE TWEEZER APPROACH FOR PROTEIN KINASE ALLOSTERIC DRUG SCREENING | MCKNIGHT, CIARA A | 1656 | §102§112 | Non-Final OA | — | Pending | Oct 06, 2023 |
| 18553600 | Monomers and Polymers with Pendant Aspirin and Compositions and Methods Thereof | FANG, SHANE | 1766 | §112 | Non-Final OA | — | Pending | Oct 02, 2023 |
| 18553357 | Specific Oligonucleotide-Programmed Readthrough of Nonsense Codons | KONOPKA, CATHERINE ANNE | 1635 | §101§102§112 | Non-Final OA | — | Pending | Sep 29, 2023 |
| 18283675 | ADIPOSE-DERIVED HYDROGEL COMPOSITIONS AND METHODS OF USE | BERTOGLIO, VALARIE E | 1632 | §102§112 | Final Rejection | — | Pending | Sep 22, 2023 |
| 18279931 | PHOTOCAGED CITRULLINE ANALOGS AND METHODS FOR SITE-SPECIFIC INCORPORATION OF CITRULLINE INTO PROTEINS | REYNOLDS, FRED H | 1658 | §102§103 | Final Rejection | 57d | Pending | Sep 01, 2023 |
| 18213505 | MODIFIED GUIDE RNAS FOR CRISPR GENOME EDITING | KONOPKA, CATHERINE ANNE | 1635 | §103§112 | Non-Final OA | — | Pending | Jun 23, 2023 |
| 18208672 | PROTEIN-TEMPLATED SELF-ASSEMBLY OF A COVALENT POLYMER NETWORK FOR INTRACELLULAR TRAFFICKING AND TRACELESS RELEASE | ROGERS, JAMES WILLIAM | 1618 | §112 | Final Rejection | 12d | Pending | Jun 12, 2023 |
| 18255661 | SYSTEM AND METHOD FOR HYDRODYNAMIC CULTIVATION OF SEED OXYGENIC PHOTOGRANULES | VARMA, AKASH K | 1773 | §103 | Final Rejection | — | Pending | Jun 02, 2023 |
| 18141166 | PROTECTING OLIGONUCLEOTIDES FOR CRISPR GUIDE RNA | MEYERING, SHABANA SHABBEER | 1635 | §103§112Other | Final Rejection | — | Pending | Apr 28, 2023 |
| 18299947 | REDOX FLOW BATTERY | AKRAM, IMRAN | 1725 | §102§103§112Other | Non-Final OA | — | Pending | Apr 13, 2023 |
| 18247157 | MARF/MFN MODULATORS AND USES THEREOF | GROOMS, TIFFANY NICOLE | 1637 | §103§112 | Non-Final OA | 37d overdue | Pending | Mar 29, 2023 |
| 18120030 | OLIGONUCLEOTIDES FOR APP MODULATION | ALLEN, SARAH ELIZABETH | 1637 | §103§112 | Final Rejection | 2d overdue | Pending | Mar 10, 2023 |
| 18021901 | DEVELOPMENT OF NOVEL GENE THERAPEUTICS FOR INFLAMMATION-INDUCED BONE LOSS | SULLIVAN, STEPHANIE LAUREN | 1635 | §112 | Non-Final OA | 27d | Pending | Feb 17, 2023 |
| 18094695 | OLIGONUCLEOTIDES FOR MECP2 MODULATION | DACE DENITO, ALEXANDRA GERALDINE | 1636 | §103§112 | Final Rejection | 22d | Pending | Jan 09, 2023 |
| 18088544 | POLYMERIC NANOPARTICLES AND DERIVATIVES THEREOF FOR NUCLEIC ACID BINDING AND DELIVERY | POPA, ILEANA | 1633 | §103Other | Final Rejection | 28d | Pending | Dec 24, 2022 |
| 18081604 | NANODEVICES AND METHODS FOR MEASURING BIOFLUIDIC FLOW USING A GRAPHENE-BASED MICROELECTRODE | MONTGOMERY, MELISSA JO | 3791 | §102§103§112 | Non-Final OA | 9d | Pending | Dec 14, 2022 |
| 18065255 | SILENCING OF DUX4 BY RECOMBINANT GENE EDITING COMPLEXES | NICOL, ALEXANDER W | 1634 | §103§112 | Non-Final OA | 79d overdue | Pending | Dec 13, 2022 |
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Start Free TrialUniversity of Massachusetts has 68 pending office actions as of October 2026, spread across 38 art units and 60 examiners.
Arthur S Leonard has the most, with 4 of University of Massachusetts's pending office actions.
Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.
