Prosecution Insights
Last updated: October 02, 2026

Examiner: BUTTICE, AUDREY L

Tech Center 1600 • Art Units: 1644 1647 1658 1683

This examiner grants 48% of resolved cases

Analysis

Audrey L. Buttice has 142 resolved cases in Tech Center 1600. The allowance rate is 47.9 percent. The median days to allowance is 1266. These 142 resolved cases are the basis for the metrics in Art Unit 1644. The 1266-day median provides a timeline for the cases resolved by this examiner and helps in estimating the duration of prosecution.

The interview lift is 25.9 percent. This metric indicates the change in allowance probability when an interview is conducted. Given the 47.9 percent allowance rate, the 25.9 percent lift is a factor for practitioners to consider. In Tech Center 1600, the lift is a data point for strategy. The 142 resolved cases reflect the examiner's experience with various applications. The 1266-day median pendency is a reference for future filings and for planning examiner engagement.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

47.9%
Allow Rate
-12.1% vs TC avg
199
Total Applications
+25.9%
Interview Lift
1266
Avg Prosecution Days
Based on 142 resolved cases, 2023–2026

Rejection Statute Breakdown

4.3%
§101 Eligibility
10.7%
§102 Novelty
40.1%
§103 Obviousness
30.2%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
18417787 BRAIN TARGETING COMPOSITIONS AND METHODS OF USE THEREOF Non-Final OA Genentech, Inc.
17774821 COMBINATION OF A T CELL THERAPY AND (S)-3-[4-(4-MORPHOLIN-4-YLMETHYL-BENZYLOXY)-L-OXO-L,3-DIHYDRO-ISOINDOL-2-YL]-PIPERIDINE-2,6-DIONE Final Rejection Juno Therapeutics, Inc.
18249057 USE OF REELIN FOR TREATING CARDIAC DISEASES Final Rejection Northwestern University
16951638 METHOD OF USING CHECKPOINT KINASE INHIBITOR THERAPY TO MODULATE ANTI-TUMORAL RESPONSE AGAINST CANCER AND SENSITIZE GLIOMAS TO IMMUNOTHERAPY Final Rejection NORTHWESTERN UNIVERSITY
18040586 METHODS AND COMPOSITIONS FOR PANCREATIC CANCER EVALUATION AND TREATMENT Final Rejection BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
18006652 ENGINEERED T CELLS AND TUMOR-INFILTRATING LYMPHOCYTES TO INCREASE TUMOR KILLING Non-Final OA Board of Regents, The University of Texas System
17242647 Method For The Degradation Of Endogenous Protein Non-Final OA University of South Carolina
18120191 PROGRAMMED CELLS FOR TARGETED ARTICULAR CARTILAGE AND BONE REGENERATION Non-Final OA University of Tennessee Research Foundation
18245281 CYTOTOXIC AND COSTIMULATORY CHIMERIC ANTIGEN RECEPTORS Final Rejection Baylor College of Medicine
18266848 CONDITIONALLY BISPECIFIC BINDING PROTEINS Non-Final OA Takeda Pharmaceutical Company Limited
18021845 COMBINATION THERAPY COMPRISING HER-2-DC1 VACCINE AND A PROBIOTIC Final Rejection H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
17434692 INDUCTION OF HIGHLY EFFICACIOUS ANTI-TUMOR AND IMMUNE MODULATING ACTIVITY: CELL-FREE OFF THE SHELF THERAPEUTIC MODALITY Final Rejection Wayne State University
18561682 HYPOIMMUNOGENIC RHD NEGATIVE PRIMARY T CELLS Non-Final OA Sana Biotechnology, Inc.
18573798 FORMULATIONS OF ANTI-PD1 ANTIBODIES Non-Final OA Formycon AG

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