Prosecution Insights
Last updated: October 02, 2026

Examiner: LIU, GUOZHEN

Tech Center 1600 • Art Units: 1631 1672 1686

This examiner grants 48% of resolved cases

Analysis

Guozhen Liu is an examiner in Tech Center 1600, working in Art Unit 1631. The examiner has 103 resolved cases. The allowance rate is 48.5 percent. This rate indicates that just under half of the applications reaching a final disposition are granted. Practitioners should be prepared for a more rigorous examination process given this 48.5 percent allowance rate.

The median days to allowance is 1600. This is a very long timeframe for the prosecution process to reach a grant. The interview lift is 25.4 percent. This figure represents a significant increase in the probability of allowance following an interview. When compared to the 48.5 percent allowance rate, the 25.4 percent lift highlights the importance of oral advocacy with this examiner.

In Art Unit 1631, the 1600 median days to allowance and 48.5 percent allowance rate suggest that prosecution may be lengthy and difficult. However, the 25.4 percent interview lift offers a significant strategic advantage. With 103 resolved cases, the data is well-supported. Practitioners should prioritize interviews to overcome the challenges reflected in the baseline allowance rate and pendency.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

48.5%
Allow Rate
-11.5% vs TC avg
138
Total Applications
+25.4%
Interview Lift
1600
Avg Prosecution Days
Based on 103 resolved cases, 2023–2026

Rejection Statute Breakdown

39.1%
§101 Eligibility
6.7%
§102 Novelty
28.0%
§103 Obviousness
19.7%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
16340738 METHOD AND APPARATUS FOR IMPROVED DETERMINATION OF NODE INFLUENCE IN A NETWORK Final Rejection UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
18027260 METHOD, APPARATUS AND DEVICE FOR IDENTIFYING SOURCE PRIMER OF NONSPECIFIC AMPLICATION SEQUENCE Non-Final OA BOE Technology Group Co., Ltd.
18474797 Cancer Score for Assessment and Response Prediction from Biological Fluids Non-Final OA Nantomics LLC
18441967 METHODS, SYSTEMS, AND COMPUTER-READABLE MEDIA FOR DETECTION OF TANDEM DUPLICATION Final Rejection Life Technologies Corporation
16341368 METHOD AND APPARATUS FOR COMPACT REPRESENTATION OF BIOINFORMATICS DATA Final Rejection KONINKLIJKE PHILIPS N.V.
17587760 PREDICTION OF SIDE-CHAIN DEGRADATION IN POLYMERS THROUGH PHYSICS BASED SIMULATIONS Final Rejection Genentech, Inc.
17204836 COUPLED MATRIX-MATRIX AND COUPLED TENSOR-MATRIX COMPLETION METHODS FOR PREDICTING DRUG-TARGET INTERACTIONS Non-Final OA THE REGENTS OF THE UNIVERSITY OF MICHIGAN
17449952 DATA SIFTING METHOD AND APPARATUS Non-Final OA DELTA ELECTRONICS, INC.
18655208 EFFICIENT CLUSTERING OF NOISY POLYNUCLEOTIDE SEQUENCE READS Final Rejection MICROSOFT TECHNOLOGY LICENSING, LLC
18264055 METHOD AND SYSTEM FOR DESIGNING PERSONALIZED THERAPEUTICS AND DIET BASED ON FUNCTIONS OF MICROBIOME Non-Final OA Tata Consultancy Services Limited
17557691 AFFINITY PREDICTION METHOD AND APPARATUS, METHOD AND APPARATUS FOR TRAINING AFFINITY PREDICTION MODEL, DEVICE AND MEDIUM Non-Final OA BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
19239357 METHODS FOR MULTI-RESOLUTION ANALYSIS OF CELL-FREE NUCLEIC ACIDS Final Rejection GUARDANT HEALTH, INC.
17092975 BACTERIAL CAPTURE SEQUENCING PLATFORM AND METHODS OF DESIGNING, CONSTRUCTING AND USING Final Rejection THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
18545231 PREDICTING NEO-ADJUVANT CHEMOTHERAPY RESPONSE FROM PRE-TREATMENT BREAST MAGNETIC RESONANCE IMAGING USING ARTIFICIAL INTELLIGENCE AND HER2 STATUS Non-Final OA Case Western Reserve University
17289882 Quantitative Algorithm for Endometriosis Final Rejection YALE UNIVERSITY
18300343 SYSTEM AND METHOD FOR SECONDARY ANALYSIS OF NUCLEOTIDE SEQUENCING DATA Final Rejection ILLUMINA, INC.
18661452 SIZE-TAGGED PREFERRED ENDS AND ORIENTATION-AWARE ANALYSIS FOR MEASURING PROPERTIES OF CELL-FREE MIXTURES Non-Final OA GRAIL, Inc.
18628166 Anomalous Fragment Detection and Classification Final Rejection GRAIL, LLC

Facing This Examiner?

IP Author analyzes examiner patterns and generates tailored response strategies with the highest chance of allowance.

Build Your Strategy

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month