Prosecution Insights
Last updated: October 02, 2026

Examiner: O'NEILL, MARISOL ANN

Tech Center 1600 • Art Units: 1633

This examiner grants 53% of resolved cases

Analysis

Marisol Ann O'Neill is an examiner in Art Unit 1633 and Tech Center 1600. She has 32 resolved cases with an allowance rate of 53.1 percent. The median days to allowance is 1256, which indicates a long duration for successful prosecution. Practitioners should prepare for a timeline that spans many days in Tech Center 1600.

The interview lift is a significant 68.2 percent. This massive increase over the 53.1 percent baseline allowance rate indicates that interviews are an extremely effective tool for advancing applications. For the 32 cases resolved, the 1256-day median pendency is a key factor to consider. Practitioners should prioritize interviews, as the 68.2 percent lift suggests they are a primary driver of success in Art Unit 1633. Navigating the 1256-day process is much more likely to result in an allowance if verbal engagement is utilized.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

53.1%
Allow Rate
-6.9% vs TC avg
56
Total Applications
+68.2%
Interview Lift
1256
Avg Prosecution Days
Based on 32 resolved cases, 2023–2026

Rejection Statute Breakdown

5.3%
§101 Eligibility
22.1%
§102 Novelty
43.2%
§103 Obviousness
21.8%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
18261954 GENE ACTIVATION TARGETS FOR ENHANCED HUMAN T CELL FUNCTION Non-Final OA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
18266093 COMPOSITIONS AND METHODS FOR GENE EDITING WITH WOOLLY MAMMOTH ALLELES Non-Final OA PRESIDENT AND FELLOWS OF HARVARD COLLEGE
18725696 USE OF IMMUNOSUPPRESSION TO ENABLE ENGRAFTMENT OF HEMATOPOIETIC STEM CELLS Non-Final OA The Board of Trustees of the Leland Stanford Junior University
17948382 METHODS OF CONTROLLING ANTIBODY HETEROGENEITY Non-Final OA Regeneron Pharmaceuticals, Inc.
18250996 PSEUDOTYPED PARTICLES, MODIFIED CELLS, RELATED COMPOSITIONS, AND RELATED METHODS Final Rejection CHILDREN'S HOSPITAL MEDICAL CENTER
18444107 METHODS AND COMPOSITIONS FOR ADMINISTERING OTOFERLIN DUAL VECTOR SYSTEMS Non-Final OA Decibel Therapeutics, Inc.
18041873 Use of Amylase or Maltose to Treat or Prevent Neurodegeneration Non-Final OA St. Jude Children's Research Hospital, Inc.
17797633 METHOD OF TREATING GENE THERAPY ASSOCIATED TOXICITY WITH ANTIBIOTICS Non-Final OA ASKBIO INC.

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