Prosecution Insights
Last updated: July 17, 2026

Sheppard Mullin Richter & Hampton Llp-Ionis Pharm

5 pending office actions • 1 client • 4 examiners • 2 art units • 0 of 5 (0%) have an AI response strategy ready • 2 patents granted in the last 365 days

Quality Metrics (n=61188 apps, methodology: how we score firms)

85.5%
Allowance Rate
n=61188
+0.58σ
Allowance Rate (norm)
n=61188
3.5
OAs to Allowance
n=29142
-0.08σ
OAs to Allow (norm)
n=29142
1035 days
Time to Allowance
n=29142
+9.8pp
Interview Lift
n=61188
32.0%
RCE Rate
n=61188
2.7%
Appeal Rate
n=61188

Rejection Performance (% of received rejections ultimately overcome)

81.4%
§101 Overcome
n=1218
83.9%
§102 Overcome
n=3893
80.3%
§103 Overcome
n=17630
87.5%
§112 Overcome
n=2818

Specialization & Scale

G06F, H04L, H04W
Top CPC Subclasses
19%
Top-3 CPC Share
n=61188
58
Practitioners
n=61188
1055.0
Apps / Practitioner
n=61188

Portfolio Summary

5
Total Pending OAs
3
Non-Final OAs
1
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 3 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 3 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
3
Medium (60%)
2
Easy (40%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only2 (40%)
§112 only2 (40%)
Double-patenting + other1 (20%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

5
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

50 h
Manual time on pending OAs
10 h
Time saved (low, 20%)
18 h
Time saved (mid, 35%)
0.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
POLIAKOVA-GEORGAN, EKATERINA 2 64.3% +17.6%
CHONG, KIMBERLY 1 72.4% +12.6%
ZARA, JANE J 1 70.8% +16.1%
ANGELL, JON E 1 70.9% +21.0%

Interview Candidates (5)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
18546462 COMPOUNDS AND METHODS FOR REDUCING NLRP3 EXPRESSION CHONG, KIMBERLY 24d overdue
17416108 MODULATORS OF HSD17B13 EXPRESSION ANGELL, JON E 4d overdue
18001848 COMPOUNDS AND METHODS FOR MODULATING PMP22 POLIAKOVA-GEORGAN, EKATERINA 3d overdue
18457941 MODULATORS OF PNPLA3 EXPRESSION POLIAKOVA-GEORGAN, EKATERINA
17508516 COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSION ZARA, JANE J

Client Portfolio (1 client)

Client (Assignee)Pending OAs
IONIS PHARMACEUTICALS, INC. 5

Top Art Units

Art UnitApps
16374
16361

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18457941 MODULATORS OF PNPLA3 EXPRESSION Ionis Pharmaceuticals, Inc. POLIAKOVA-GEORGAN, EKATERINA 1637 DPOther Non-Final OA Pending Aug 29, 2023
18546462 COMPOUNDS AND METHODS FOR REDUCING NLRP3 EXPRESSION Ionis Pharmaceuticals, Inc. CHONG, KIMBERLY 1636 §112 Non-Final OA 24d overdue Pending Aug 15, 2023
18001848 COMPOUNDS AND METHODS FOR MODULATING PMP22 Ionis Pharmaceuticals, Inc. POLIAKOVA-GEORGAN, EKATERINA 1637 §103 Non-Final OA 3d overdue Pending Dec 14, 2022
17508516 COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSION Ionis Pharmaceuticals, Inc. ZARA, JANE J 1637 §103 Non-Final OA Pending Oct 22, 2021
17416108 MODULATORS OF HSD17B13 EXPRESSION Ionis Pharmaceuticals, Inc. ANGELL, JON E 1637 §112 Final Rejection 4d overdue Pending Jun 18, 2021

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