Prosecution Insights
Last updated: October 25, 2026

City of Hope

Technology area: Biotechnology & Pharmaceuticals

48 pending office actions • 30 art units • 47 examiners • 0 of 48 (0%) have an AI response strategy ready • 47 patents granted in the last 365 days

Analysis

City of Hope has 47 pending office actions in Biotechnology & Pharmaceuticals. The matters involve 46 distinct examiners and 29 distinct art units, creating a prosecution program spread across many examiner relationships and examination groups. The difference between the pending-action volume and examiner count indicates that at least some examiner assignments contain more than one current matter, while the art-unit distribution adds another layer of coordination.

BELYAVSKYI, MICHAIL A is the busiest examiner, with 2 pending matters. That is the largest reported individual examiner assignment, but it represents only a limited portion of the overall docket. Counsel should use centralized tracking for deadlines and recurring biotechnology or pharmaceutical positions, while preserving application-specific analysis for the many examiner and art-unit contexts.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

48
Total Pending OAs
29
Non-Final OAs
15
Final Rejections
4
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 24 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

13
Overdue
0
Due this week
9
Due this month
1
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 24 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (13)Due ≤ 30 days (9)Due ≤ 60 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

19
Hard (40%)
24
Medium (50%)
5
Easy (10%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only13 (27%)
§102 only3 (6%)
§112 only5 (10%)
Double-patenting + other8 (17%)
Multi-statute (no §101)19 (40%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

45
Life Sciences
94% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
3
Mechanical / Eng
6% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

480 h
Manual time on pending OAs
96 h
Time saved (low, 20%)
168 h
Time saved (mid, 35%)
4.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
BELYAVSKYI, MICHAIL A 2 63.9% +28.0%
WARD, PAUL V 1 83.2% -12.2%
POPA, ILEANA 1 21.7% +15.7%
PAK, MICHAEL D 1 58.6% +29.9%
BURKHART, MICHAEL D 1 62.4% +11.8%
KINSEY WHITE, NICOLE ERIN 1 58.1% +16.5%
CHESTNUT, BARRY A 1 73.9% +6.3%
WANG, RUIXUE 1 55.9% +19.0%
GIBBS, TERRA C 1 63.7% +10.4%
GANGLE, BRIAN J 1 76.8% +14.6%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18842728 PCNA INHIBITORS AND USES THEREOF WARD, PAUL V —

Hard Cases (20)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18279581 MUC16 PROMOTER CONTAINING VIRUS ALAM, DANYAL HASSAN 32d overdue
18255503 PREVENTION AND TREATMENT OF GRAFT-VERSUS-HOST DISEASE (GVHD) CESARE, JOSEPH DAVID 8d overdue
17976670 NASAL SWAB KREMER, MATTHEW 3d overdue
18284413 CAR T CELL THERAPY AND IFN GAMMA LEE, YIE CHIA 9d
18265544 COMPOUNDS AND METHODS TO TREAT CYSTIC FIBROSIS PRONZATI, GINA 12d
18026335 EX VIVO EXPANSION OF REGULATORY T CELLS FOR SUPPRESSION OF GRAFT VERSUS HOST DISEASE JUEDES, AMY E 15d
18361492 METHODS OF TREATING A CORONAVIRUS INFECTION KLINKEL, KORTNEY L 28d
18653869 COMPOSITIONS AND METHODS OF ALLEVIATING RESISTANCE TO CHEMOTHERAPY GIBBS, TERRA C 29d

Interview Candidates (9)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18277367 TRUNCATED DOMAIN IV EGFR AND USES THEREOF BELYAVSKYI, MICHAIL A 28d overdue
18653869 COMPOSITIONS AND METHODS OF ALLEVIATING RESISTANCE TO CHEMOTHERAPY GIBBS, TERRA C 29d
18816718 T CELLS FOR EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS AND OTHER RECEPTORS POPA, ILEANA —
18757218 MULTI-SPECIFIC LIGAND BINDERS PAK, MICHAEL D —
18754973 METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPY BURKHART, MICHAEL D —
18711338 METHODS OF PREVENTING, TREATING, OR REDUCING THE SEVERITY OF CORONAVIRUS DISEASE 2019 (COVID-19) KINSEY WHITE, NICOLE ERIN —
18711088 METHODS OF PREVENTING, TREATING, OR REDUCING THE SEVERITY OF COVID-19 IN IMMUNOCOMPROMISED BLOOD CANCER PATIENTS WANG, RUIXUE —
18702614 CLOSTRIDIUM BUTYRICUM COMPOSITIONS AND METHODS OF USING THE SAME GANGLE, BRIAN J —

Top Art Units

Art UnitApps
1672 4
1675 4
1633 3
1644 3
1638 2
1635 2
1645 2
1632 2
1642 2
1637 2

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18842728 PCNA INHIBITORS AND USES THEREOF WARD, PAUL V 1622 §112 Non-Final OA — Pending Aug 29, 2024
18816718 T CELLS FOR EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS AND OTHER RECEPTORS POPA, ILEANA 1633 §103 Non-Final OA — Pending Aug 27, 2024
18757218 MULTI-SPECIFIC LIGAND BINDERS PAK, MICHAEL D 1674 §102DP Non-Final OA — Pending Jun 27, 2024
18754973 METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPY BURKHART, MICHAEL D 1638 §102 Non-Final OA — Pending Jun 26, 2024
18711338 METHODS OF PREVENTING, TREATING, OR REDUCING THE SEVERITY OF CORONAVIRUS DISEASE 2019 (COVID-19) KINSEY WHITE, NICOLE ERIN 1672 §102§103§112DP Non-Final OA — Pending May 17, 2024
18711073 SYNTHETIC MODIFIED VACCINIA ANKARA (SMVA) BASED CORONAVIRUS VACCINES CHESTNUT, BARRY A 1672 §102§103§112DP Non-Final OA — Pending May 16, 2024
18711088 METHODS OF PREVENTING, TREATING, OR REDUCING THE SEVERITY OF COVID-19 IN IMMUNOCOMPROMISED BLOOD CANCER PATIENTS WANG, RUIXUE 1672 §103§112 Non-Final OA — Pending May 16, 2024
18653869 COMPOSITIONS AND METHODS OF ALLEVIATING RESISTANCE TO CHEMOTHERAPY GIBBS, TERRA C 1635 §102§103 Non-Final OA 29d Pending May 02, 2024
18702614 CLOSTRIDIUM BUTYRICUM COMPOSITIONS AND METHODS OF USING THE SAME GANGLE, BRIAN J 1645 §102§112Other Non-Final OA — Pending Apr 18, 2024
18682713 CHIMERIC ANTIGEN RECEPTOR T CELLS TARGETING gD AND ONCOLYTIC VIRUSES FOR CANCER THERAPY AND TREATMENT OF HSV LANDSMAN, ROBERT S 1647 §103 Non-Final OA — Pending Feb 09, 2024
18567094 COMPOSITIONS AND METHODS FOR ISLET CELL TRANSPLANTS GRABER, JAMES J 1631 §102§103 Non-Final OA — Pending Dec 05, 2023
18288692 PCNA INHIBITORS AND EGFR INHIBITORS FOR CANCER TREATMENT WELLS, LAUREN QUINLAN 1626 §103DP Final Rejection — Pending Oct 27, 2023
18488859 TREATMENT OF CANAVAN DISEASE BERTOGLIO, VALARIE E 1632 §102Other Final Rejection 21d Pending Oct 17, 2023
18554286 CANCER TREATMENT BY TARGETING PROTEINS OR INTERACTIONS OF EPHRINB-RGS3-KIF20A-SEPT7 AXIS MEYERING, SHABANA SHABBEER 1635 §102§103§112 Non-Final OA — Pending Oct 06, 2023
18284413 CAR T CELL THERAPY AND IFN GAMMA LEE, YIE CHIA 1642 §103§112 Final Rejection 9d Pending Sep 27, 2023
18548677 T-CELLS FOR ANTI-HIV CAR-T THERAPY AND METHODS OF USE CHASE, CAROL ANN 1646 §103§112 Non-Final OA — Pending Sep 01, 2023
18279581 MUC16 PROMOTER CONTAINING VIRUS ALAM, DANYAL HASSAN 1672 §103§112 Final Rejection 32d overdue Pending Aug 30, 2023
18277367 TRUNCATED DOMAIN IV EGFR AND USES THEREOF BELYAVSKYI, MICHAIL A 1644 §103 Non-Final OA 28d overdue Pending Aug 15, 2023
18361492 METHODS OF TREATING A CORONAVIRUS INFECTION KLINKEL, KORTNEY L 1627 §102§103§112 Non-Final OA 28d Pending Jul 28, 2023
18220070 PREVENTION OR TREATMENT OF WASTING SYNDROME GROOMS, TIFFANY NICOLE 1637 §112 Non-Final OA 2d overdue Pending Jul 10, 2023
18266443 COMPOSITIONS AND USES OF CD19 TARGETED CHIMERIC ANTIGEN RECEPTOR MODIFIED IMMUNE CELLS BENAVIDES, JENNIFER ANN 1675 §103 Final Rejection 70d Pending Jun 09, 2023
18265544 COMPOUNDS AND METHODS TO TREAT CYSTIC FIBROSIS PRONZATI, GINA 1633 §102§103 Non-Final OA 12d Pending Jun 06, 2023
18255503 PREVENTION AND TREATMENT OF GRAFT-VERSUS-HOST DISEASE (GVHD) CESARE, JOSEPH DAVID 1675 §102§103§112 Final Rejection 8d overdue Pending Jun 01, 2023
18038423 COMPOSITIONS AND USES OF PSCA TARGETED CHIMERIC ANTIGEN RECEPTOR MODIFIED CELLS FAUST, AMBER KATHLEEN 1643 §103DP Final Rejection 42d overdue Pending May 23, 2023
18033777 ENGINEERED NK CELLS HAM, JIEUN 1643 §102§103Other Non-Final OA 56d Pending Apr 25, 2023
18032201 HYDROPHOBIC DRUGS IN ORGANIC CORE HIGH DENSITY LIPOPROTEIN (HDL) NANOPARTICLES AL-AWADI, DANAH J 1615 §103§112DP Final Rejection 66d overdue Pending Apr 17, 2023
18296224 TREATMENT OF CANAVAN DISEASE TAKENAKA, RISA 1632 §112 Non-Final OA — Pending Apr 05, 2023
18026335 EX VIVO EXPANSION OF REGULATORY T CELLS FOR SUPPRESSION OF GRAFT VERSUS HOST DISEASE JUEDES, AMY E 1644 §103§112 Non-Final OA 15d Pending Mar 14, 2023
18022708 COMPOSITIONS AND METHODS FOR G-PROTEIN-COUPLED RECEPTOR 44 DETECTION CRAIG, KAILA ANGELIQUE 1618 §103§112 Non-Final OA — Pending Feb 22, 2023
18042434 LAMP DETECTION OF SARS-COV-2 IN SALIVA FOR THE RAPID DIAGNOSIS OF COVID-19 SWITZER, JULIET CAROLINE 1682 §103 Final Rejection 23d overdue Pending Feb 21, 2023
18020858 COMPOSITIONS AND USES OF SARS-COV-2 TARGETED CHIMERIC ANTIGEN RECEPTOR MODIFIED NK CELLS BELYAVSKYI, MICHAIL A 1644 §103§112 Non-Final OA — Pending Feb 10, 2023
18017982 TREATMENTS FOR CANCERS HAVING KRAS MUTATIONS MARTINEZ, TARA L 1654 §103Other Final Rejection 29d Pending Jan 25, 2023
18017841 PEPTIDE DESIGN AND GALECTIN-3 INHIBITORS MACFARLANE, STACEY NEE 1675 §103 Non-Final OA 36d overdue Pending Jan 24, 2023
18066132 MULTIVALENT MEDITOPES, MEDITOPE-BINDING ANTIBODIES AND USES THEREOF DIBRINO, MARIANNE 1641 §112 Final Rejection 50d overdue Pending Dec 14, 2022
18073397 3 FLAP OKAZAKI FRAGMENTS AND USES THEREOF VANN-OJUEKAIYE, KENDRA RAYCHELL 1682 §103§112 Final Rejection — Pending Dec 01, 2022
17998469 COMPOSITIONS AND METHODS FOR BASE SPECIFIC MITOCHONDRIAL GENE EDITING WHITEMAN, BRIAN A 1636 §103 Non-Final OA — Pending Nov 10, 2022
17998011 METHODS FOR ORGANOIDS PRODUCTION MARCHESCHI, MICHAEL A 1796 §102§103§112 Non-Final OA — Pending Nov 04, 2022
17976670 NASAL SWAB KREMER, MATTHEW 3791 §103§112 Non-Final OA 3d overdue Pending Oct 28, 2022
17997351 TAGGED GENE EDITING TECHNOLOGY FOR CLINICAL CELL SORTING AND ENRICHMENT PYLA, EVELYN Y 1633 §103 Non-Final OA — Pending Oct 27, 2022
17932239 SYNTHETIC MODIFIED VACCINIA ANKARA (sMVA) BASED CORONAVIRUS VACCINES QIAN, CELINE X 1637 §103§112DP Final Rejection 217d overdue Pending Sep 14, 2022
17910459 DUAL-TARGETING CHIMERIC ANTIGEN RECEPTOR MODIFIED T CELLS COMPRISING IL-13 AND CHLOROTOXIN FOR CANCER TREATMENT VIVLEMORE, TRACY ANN 1638 §103 Non-Final OA 9d overdue Pending Sep 09, 2022
17870024 CHIMERIC ANTIGEN RECEPTOR T CELLS TARGETING CEA AND ANTI-CEA-IL2 IMMUNOCYTOKINES FOR CANCER THERAPY PATTERSON, SARAH COOPER 1675 §103 Non-Final OA — Pending Jul 21, 2022
17843073 ACCESS NEEDLE SYSTEMS AND METHODS LI, JOHN DENNY 3798 §103 Non-Final OA 29d Pending Jun 17, 2022
17767398 CANCER COMBINATION TREATMENTS USING ANTI-STAT3 NUCLEIC ACID CONJUGATES STONEBRAKER, ALYSSA RAE 1642 §103§112DPOther Non-Final OA — Pending Apr 07, 2022
17520402 CHIMERIC ANTIGEN RECEPTORS CONTAINING A CHLOROTOXIN DOMAIN HINES, JANA A 1645 §103 Final Rejection 110d overdue Pending Nov 05, 2021
17184987 Surgical Gauze ARBLE, JESSICA R 3781 §102 Non-Final OA 26d Pending Feb 25, 2021
16968504 PROMOTING AND PROTECTING FUNCTIONAL BETA CELL MASS BY SYNTAXIN 4 ENRICHMENT CONNORS, ALEXANDRA F 1634 §103§112 Non-Final OA — Pending Aug 07, 2020
16604151 P38 GAMMA INHIBITORS AND METHOD OF USE THEREOF LEE, ANDREW P 1691 §112 Final Rejection — Pending Oct 09, 2019

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Frequently Asked Questions

How many pending USPTO office actions does City of Hope have?

City of Hope has 48 pending office actions as of October 2026, spread across 30 art units and 47 examiners.

Which USPTO examiner handles the most City of Hope applications?

Michail A Belyavskyi has the most, with 2 of City of Hope's pending office actions.

What technology area are City of Hope's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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