Prosecution Insights
Last updated: October 04, 2026

Cue Biopharma Inc.

Technology area: Biotechnology & Pharmaceuticals

6 pending office actions • 4 art units • 6 examiners • 0 of 6 (0%) have an AI response strategy ready • 3 patents granted in the last 365 days

Analysis

Cue Biopharma Inc. maintains a patent portfolio within the Biotechnology & Pharmaceuticals technology area. The company currently faces 5 pending office actions that are being processed by 5 distinct examiners. Because the number of 5 distinct examiners is equal to the number of 5 pending office actions, each examiner is currently responsible for a single matter for the portfolio.

These prosecution efforts are spread across 4 distinct art units. CLAUDIA EDILMA ESPINOSA is the busiest examiner for the company, with 1 pending office action under review. This workload for CLAUDIA EDILMA ESPINOSA represents 1 of the 5 pending office actions currently active for Cue Biopharma Inc. The use of 4 distinct art units suggests the portfolio covers multiple technical sub-sectors within its technology area.

The presence of 5 pending office actions across 4 distinct art units indicates that the company is engaging with several different examination groups. This distribution can prevent a single examiner from impacting the entire portfolio. With CLAUDIA EDILMA ESPINOSA and the other examiners each managing 1 pending office action, the workload is distributed across the 5 distinct examiners. Practitioners should note that the coverage of 4 distinct art units may require different technical approaches for each unit.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

6
Total Pending OAs
5
Non-Final OAs
1
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 1 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

1
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
0
Due later

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

3
Hard (50%)
3
Medium (50%)
0
Easy (0%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
Double-patenting + other3 (50%)
Multi-statute (no §101)3 (50%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

6
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

60 h
Manual time on pending OAs
12 h
Time saved (low, 20%)
21 h
Time saved (mid, 35%)
0.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
ESPINOSA, CLAUDIA EDILMA 1 50.9% +57.7%
ZOU, NIANXIANG 1 64.1% +24.8%
STOICA, ELLY GERALD 1 66.9% +22.5%
AEDER, SEAN E 1 57.0% +19.9%
QIAN, CELINE X 1 47.6% +16.9%
BLUMEL, BENJAMIN P 1 70.8% +30.5%

Hard Cases (3)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 3 ordered by deadline are shown.

App #TitleExaminerDue in
18005813 T-Cell Modulatory Polypeptides with Conjugation Sites and Methods of Use Thereof QIAN, CELINE X 18d overdue
18903947 T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF ESPINOSA, CLAUDIA EDILMA —
17822584 T CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF BLUMEL, BENJAMIN P —

Interview Candidates (6)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
18005813 T-Cell Modulatory Polypeptides with Conjugation Sites and Methods of Use Thereof QIAN, CELINE X 18d overdue
18903947 T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF ESPINOSA, CLAUDIA EDILMA —
18653683 MULTIMERIC T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF ZOU, NIANXIANG —
18287747 Antigen Presenting Polypeptide Complexes Bearing TGF-Beta and Methods of Use Thereof STOICA, ELLY GERALD —
18287739 Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof AEDER, SEAN E —
17822584 T CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF BLUMEL, BENJAMIN P —

Top Art Units

Art UnitApps
1654 2
1671 2
1647 1
1637 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18903947 T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF ESPINOSA, CLAUDIA EDILMA 1654 §103§112Other Non-Final OA — Pending Oct 01, 2024
18653683 MULTIMERIC T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF ZOU, NIANXIANG 1671 §103§112DP Non-Final OA — Pending May 02, 2024
18287747 Antigen Presenting Polypeptide Complexes Bearing TGF-Beta and Methods of Use Thereof STOICA, ELLY GERALD 1647 §112DP Non-Final OA — Pending Oct 20, 2023
18287739 Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof AEDER, SEAN E 1654 §112DP Non-Final OA — Pending Oct 20, 2023
18005813 T-Cell Modulatory Polypeptides with Conjugation Sites and Methods of Use Thereof QIAN, CELINE X 1637 §102§103§112Other Final Rejection 18d overdue Pending Jan 17, 2023
17822584 T CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF BLUMEL, BENJAMIN P 1671 §103§112 Non-Final OA — Pending Aug 26, 2022

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