Prosecution Insights
Last updated: October 02, 2026

Gritstone Bio Inc.

Technology area: Biotechnology & Pharmaceuticals

14 pending office actions • 9 art units • 14 examiners • 0 of 14 (0%) have an AI response strategy ready • 4 patents granted in the last 365 days

Analysis

Gritstone Bio Inc. has 13 pending office actions in the Biotechnology & Pharmaceuticals technology area. These actions are assigned to 13 distinct examiners and 8 distinct art units. The fact that there are 13 actions and 13 examiners indicates that every pending application is currently being reviewed by a different individual. This one-to-one ratio between 13 pending office actions and 13 distinct examiners suggests a highly decentralized prosecution experience.

CHESTNUT, BARRY A is the busiest examiner, with 1 pending office action. The involvement of 8 distinct art units shows that the company's biotechnology portfolio is spread across several specialized groups. This distribution requires a broad prosecution approach to account for the different standards and examiner behaviors across 13 distinct individuals. Managing 13 pending office actions across 8 distinct art units means the company must be prepared for varied administrative requirements and examination timelines.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

14
Total Pending OAs
8
Non-Final OAs
5
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 2 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
0
Due later

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

8
Hard (57%)
4
Medium (29%)
2
Easy (14%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other5 (36%)
§103 only1 (7%)
§102 only1 (7%)
§112 only2 (14%)
Double-patenting + other2 (14%)
Multi-statute (no §101)3 (21%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

13
Life Sciences
93% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
7% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

140 h
Manual time on pending OAs
28 h
Time saved (low, 20%)
49 h
Time saved (mid, 35%)
1.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
CHESTNUT, BARRY A 1 73.5% +6.4%
GODDARD, LAURA B 1 50.9% +13.5%
GRIZER, CASSANDRA SENN 1 75.0% +18.8%
JADHAO, SAMADHAN JAISING 1 46.9% +46.2%
DAHLE, CHUN WU 1 50.2% +51.2%
MACFARLANE, STACEY NEE 1 53.5% +39.6%
LIPPOLIS, ALEXANDRA ROSE 1 46.9% +59.0%
CHEN, STACY BROWN 1 66.1% +40.6%
LEE, YIE CHIA 1 69.2% +46.6%
VIVLEMORE, TRACY ANN 1 73.0% +6.6%

Hard Cases (8)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
16975823 Neoantigen Identification with Pan-Allele Models BAILEY, STEVEN WILLIAM 45d overdue
18658604 SELF-AMPLIFYING RNA COMPOSITIONS AND METHODS OF USE THEREOF CHESTNUT, BARRY A —
18504497 REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS GODDARD, LAURA B —
18272087 HOMOLOGOUS ADENOVIRAL VACCINATION GRIZER, CASSANDRA SENN —
17817312 HIV ANTIGENS AND MHC COMPLEXES LIPPOLIS, ALEXANDRA ROSE —
17744354 ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS LEE, YIE CHIA —
17581788 NEOANTIGEN IDENTIFICATION USING HOTSPOTS WOITACH, JOSEPH T —
17436367 IDENTIFICATION OF NEOANTIGENS WITH MHC CLASS II MODEL NGUYEN, PETER —

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18504497 REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS GODDARD, LAURA B —
18272087 HOMOLOGOUS ADENOVIRAL VACCINATION GRIZER, CASSANDRA SENN —
18255539 COMPOSITIONS AND METHODS OF USE THEREOF JADHAO, SAMADHAN JAISING —
18018400 ENGINEERED MULTI-SPECIFIC ANTIBODIES AND RELATED METHODS OF USE AND MANUFACTURE DAHLE, CHUN WU —
17426627 MULTISPECIFIC BINDING PROTEINS MACFARLANE, STACEY NEE —
17817312 HIV ANTIGENS AND MHC COMPLEXES LIPPOLIS, ALEXANDRA ROSE —
17838114 DURABLE VACCINATION CHEN, STACY BROWN —
17744354 ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS LEE, YIE CHIA —

Top Art Units

Art UnitApps
1672 3
1642 2
1687 2
1641 1
1675 1
1637 1
1638 1
1685 1
1643 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18658604 SELF-AMPLIFYING RNA COMPOSITIONS AND METHODS OF USE THEREOF CHESTNUT, BARRY A — §103§112 Non-Final OA — Pending May 08, 2024
18504497 REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS GODDARD, LAURA B 1642 §101§103§112DP Non-Final OA — Pending Nov 08, 2023
18272087 HOMOLOGOUS ADENOVIRAL VACCINATION GRIZER, CASSANDRA SENN 1672 §103§112 Non-Final OA — Pending Jul 12, 2023
18255539 COMPOSITIONS AND METHODS OF USE THEREOF JADHAO, SAMADHAN JAISING 1672 §102§103§112DP Non-Final OA — Pending Jun 01, 2023
18018400 ENGINEERED MULTI-SPECIFIC ANTIBODIES AND RELATED METHODS OF USE AND MANUFACTURE DAHLE, CHUN WU 1641 §112 Non-Final OA — Pending Jan 27, 2023
17426627 MULTISPECIFIC BINDING PROTEINS MACFARLANE, STACEY NEE 1675 §112 Non-Final OA — Pending Sep 16, 2022
17817312 HIV ANTIGENS AND MHC COMPLEXES LIPPOLIS, ALEXANDRA ROSE 1637 §103§112 Non-Final OA — Pending Aug 03, 2022
17838114 DURABLE VACCINATION CHEN, STACY BROWN 1672 §103§112DP Final Rejection — Pending Jun 10, 2022
17744354 ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS LEE, YIE CHIA 1642 §101§102§103§112 Non-Final OA — Pending May 13, 2022
17736738 SHARED NEOANTIGEN VACCINES VIVLEMORE, TRACY ANN 1638 §102Other Final Rejection 141d overdue Pending May 04, 2022
17581788 NEOANTIGEN IDENTIFICATION USING HOTSPOTS WOITACH, JOSEPH T 1687 §101§112Other Non-Final OA — Pending Jan 21, 2022
17436367 IDENTIFICATION OF NEOANTIGENS WITH MHC CLASS II MODEL NGUYEN, PETER 1685 §101§103DP Final Rejection — Pending Sep 03, 2021
17433817 SELECTION OF T CELL RECEPTORS FAUST, AMBER KATHLEEN 1643 §103 Final Rejection — Pending Aug 25, 2021
16975823 Neoantigen Identification with Pan-Allele Models BAILEY, STEVEN WILLIAM 1687 §101§103§112DP Final Rejection 45d overdue Pending Aug 26, 2020

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