Prosecution Insights
Last updated: October 01, 2026

Examiner: LIPPOLIS, ALEXANDRA ROSE

Tech Center 6200 • Art Units: 1632 1637 1645 6221

This examiner grants 47% of resolved cases

Analysis

Alexandra Rose Lippolis serves in Tech Center 6200 and Art Unit 1632. The examiner has 32 resolved cases. The allowance rate is 46.9 percent. This rate indicates that fewer than half of the applications reaching a final disposition are granted. With 32 resolved cases, practitioners should be aware that the data set is smaller than that of more veteran examiners.

The median days to allowance is 1431. This is a relatively long timeframe for reaching a successful conclusion in prosecution. The interview lift is 59.0 percent. This is an exceptionally high lift, representing a massive increase in the probability of allowance when an interview is held. Compared to the 46.9 percent allowance rate, the 59.0 percent lift suggests that interviews are a transformative tool for this examiner.

For those in Art Unit 1632, the 59.0 percent interview lift is the most critical metric in the profile. The 1431 median days to allowance indicates that prosecution may be lengthy. However, the 46.9 percent allowance rate can be significantly improved through direct engagement. The data suggests that oral advocacy is essential for overcoming the challenges of the baseline examination process.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

46.9%
Allow Rate
-13.1% vs TC avg
95
Total Applications
+59.0%
Interview Lift
1431
Avg Prosecution Days
Based on 32 resolved cases, 2023–2026

Rejection Statute Breakdown

5.7%
§101 Eligibility
18.4%
§102 Novelty
42.9%
§103 Obviousness
26.4%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
18456037 MODIFIED CYANOBACTERIUM, MODIFIED CYANOBACTERIUM PRODUCTION METHOD, AND PROTEIN PRODUCTION METHOD Final Rejection Panasonic Intellectual Property Management Co., Ltd.
17748617 MODIFIED CYANOBACTERIUM, MODIFIED CYANOBACTERIUM PRODUCTION METHOD, AND PROTEIN PRODUCTION METHOD Non-Final OA Panasonic Intellectual Property Management Co., Ltd.
18568796 IMPROVED CYTOSINE TO GUANINE BASE EDITORS Non-Final OA Massachusetts Institute of Technology
18248199 HELITRON MEDIATED GENETIC MODIFICATION Non-Final OA MASSACHUSETTS INSTITUTE OF TECHNOLOGY
17776269 SMALL TYPE II CAS PROTEINS AND METHODS OF USE THEREOF Final Rejection MASSACHUSETTS INSTITUTE OF TECHNOLOGY
17422490 SYSTEMS AND METHODS FOR CULTURING CELLS IN SUSPENSION Non-Final OA CORNING INCORPORATED
17913723 LINKED DNA PRODUCTION METHOD AND VECTOR COMBINATION FOR USE THEREIN Non-Final OA THE UNIVERSITY OF TOKYO
17733265 DNA CAPTURE-BASED GRAVITATIONAL FLOW-THROUGH ASSAY FOR ANTIGEN DETECTION Non-Final OA University of South Florida
18025446 TARGETED DEAMINASE AND BASE EDITING USING SAME Final Rejection INSTITUTE FOR BASIC SCIENCE
18415949 INTEIN TECHNOLOGY TO DELIVER ABCA3 LIPID TRANSPORTER FOR ABCA3 DEFICIENCY Non-Final OA Children's Hospital Medical Center
18264885 COMPOSITIONS AND METHODS FOR TREATING PULMONARY ARTERIAL HYPERTENSION (PAH) AND OTHER DISORDERS Non-Final OA THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
18180718 SYSTEMS AND METHODS FOR GENOME-WIDE ANNOTATION OF GENE REGULATORY ELEMENTS LINKED TO CELL FITNESS Final Rejection Duke University
17759564 CELL SPECIFIC, SELF-INACTIVATING GENOMIC EDITING USING CRISPR-CAS SYSTEMS HAVING RNASE AND DNASE ACTIVITY Final Rejection Icahn School of Medicine at Mount Sinai
17602204 HYBRID NUCLEIC ACID SWITCHES Final Rejection The United States of America,as represented by the Secretary,Department of Health and Human Services
18293091 SMALL MOLECULE AND SIRNA INHIBITORS AGAINST LIPOCALIN-2 Non-Final OA UNIVERSITY OF PUERTO RICO
18268251 NUCLEIC ACID CONSTRUCT FOR AIDS GENE THERAPY Non-Final OA KANGLIN BIOTECH (HANGZHOU) CO., LTD

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