Prosecution Insights
Last updated: October 02, 2026

Merus N V

Technology area: Biotechnology & Pharmaceuticals

16 pending office actions • 6 art units • 12 examiners • 0 of 16 (0%) have an AI response strategy ready • 4 patents granted in the last 365 days

Analysis

Merus N V maintains a portfolio in the Biotechnology & Pharmaceuticals technology area with 16 pending office actions. These actions are distributed across 12 distinct examiners and 6 distinct art units. The busiest examiner for the company is WEHBE, ANNE MARIE SABRINA, who is currently handling 2 pending office actions.

The distribution of 16 pending office actions among 12 distinct examiners suggests that the portfolio is not overly concentrated under any single individual. The 6 distinct art units involved show that the company's intellectual property spans multiple sub-specialties within the Biotechnology & Pharmaceuticals sector. This diversity requires managing various examiner styles and art unit tendencies simultaneously.

WEHBE, ANNE MARIE SABRINA, as the busiest examiner with 2 pending office actions, represents a small portion of the total workload. This indicates that the portfolio's success is dependent on a wide range of examiner interactions rather than a single point of contact. The ratio of 12 distinct examiners to these pending actions reflects a high degree of variety in the prosecution landscape.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

16
Total Pending OAs
7
Non-Final OAs
9
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 9 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
1
Due this week
4
Due this month
1
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 9 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (2)Due ≤ 7 days (1)Due ≤ 30 days (4)Due ≤ 60 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

6
Hard (38%)
6
Medium (38%)
3
Easy (19%)
1
Unknown (6%)

Rejection Statute Mix

BucketCases
§101 + other1 (6%)
§103 only2 (12%)
§102 only1 (6%)
§112 only3 (19%)
Double-patenting + other3 (19%)
Multi-statute (no §101)5 (31%)
No statute on record1 (6%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

16
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

160 h
Manual time on pending OAs
32 h
Time saved (low, 20%)
56 h
Time saved (mid, 35%)
1.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
WEHBE, ANNE MARIE SABRINA 2 57.2% +43.4%
NICKOL, GARY B 2 47.1% +31.1%
BRISTOL, LYNN ANNE 2 63.4% +39.8%
ALSOMAIRY, SARAH ABDOALATIF 2 57.8% +30.2%
CHASE, CAROL ANN 1 42.6% +84.7%
HOPPE, EMMA RUTH 1 42.1% +56.8%
LI, RUIXIANG 1 59.5% +18.6%
GODDARD, LAURA B 1 50.9% +13.5%
MOSELEY II, NELSON B 1 68.0% +41.5%
SHUPE, ELIZABETH A 1 66.2% +44.2%

Hard Cases (6)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
17431044 COMBINATIONS OF BINDING MOIETIES THAT BIND EGFR, HER2 AND HER3 ALSOMAIRY, SARAH ABDOALATIF 30d overdue
18566982 NEW NRG1 FUSIONS, FUSION JUNCTIONS AND METHODS FOR DETECTING THEM HOPPE, EMMA RUTH —
18460482 ANTIBODY PRODUCING NON-HUMAN ANIMALS WEHBE, ANNE MARIE SABRINA —
18449460 ERBB-2 AND ERBB3 BINDING BISPECIFIC ANTIBODIES FOR USE IN THE TREATMENT OF CELLS THAT HAVE AN NRG1 FUSION GENE LI, RUIXIANG —
18257804 MULTISPECIFIC ANTIBODIES FOR THE TREATMENT OF CANCER NICKOL, GARY B —
17431041 PRODUCING COMPOSITIONS COMPRISING TWO OR MORE ANTIBODIES FAUST, AMBER KATHLEEN —

Interview Candidates (14)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17431044 COMBINATIONS OF BINDING MOIETIES THAT BIND EGFR, HER2 AND HER3 ALSOMAIRY, SARAH ABDOALATIF 30d overdue
18257528 TREATMENT OF CANCERS WITH AN ANTIBODY THAT BINDS LGR5 AND EGFR NICKOL, GARY B 23d overdue
18251832 MEANS AND METHODS FOR TREATING SUBJECTS WITH ERBB3 MUTATION POSITIVE CANCER GODDARD, LAURA B 6d
18062871 BINDING MOLECULES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL MOSELEY II, NELSON B 22d
17926283 METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES BRISTOL, LYNN ANNE 27d
17921042 TREATMENT OF CANCERS WITH AN ANTIBODY THAT BINDS LGR5 AND EGFR SHUPE, ELIZABETH A 29d
18419527 ANTIBODY THAT BINDS ERBB-2 AND ERBB-3 CHASE, CAROL ANN 42d
17755196 MEANS AND METHODS FOR TREATING SUBJECTS WITH HER2 AND HER3 POSITIVE CANCER BRISTOL, LYNN ANNE 70d

Top Art Units

Art UnitApps
1643 6
1646 3
1634 2
1674 2
1642 2
1683 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18419527 ANTIBODY THAT BINDS ERBB-2 AND ERBB-3 CHASE, CAROL ANN 1646 Other Final Rejection 42d Pending Jan 22, 2024
18566982 NEW NRG1 FUSIONS, FUSION JUNCTIONS AND METHODS FOR DETECTING THEM HOPPE, EMMA RUTH 1683 §101§102§112DP Non-Final OA — Pending Dec 04, 2023
18464173 ANTIBODY PRODUCING NON-HUMAN ANIMALS WEHBE, ANNE MARIE SABRINA 1634 §102 Final Rejection — Pending Sep 08, 2023
18460482 ANTIBODY PRODUCING NON-HUMAN ANIMALS WEHBE, ANNE MARIE SABRINA 1634 §102§103§112Other Final Rejection — Pending Sep 01, 2023
18449460 ERBB-2 AND ERBB3 BINDING BISPECIFIC ANTIBODIES FOR USE IN THE TREATMENT OF CELLS THAT HAVE AN NRG1 FUSION GENE LI, RUIXIANG 1674 §103§112 Non-Final OA — Pending Aug 14, 2023
18257804 MULTISPECIFIC ANTIBODIES FOR THE TREATMENT OF CANCER NICKOL, GARY B 1643 §102§103§112 Final Rejection — Pending Jun 15, 2023
18257528 TREATMENT OF CANCERS WITH AN ANTIBODY THAT BINDS LGR5 AND EGFR NICKOL, GARY B 1643 §103 Final Rejection 23d overdue Pending Jun 14, 2023
18251832 MEANS AND METHODS FOR TREATING SUBJECTS WITH ERBB3 MUTATION POSITIVE CANCER GODDARD, LAURA B 1642 §102§103§112DP Final Rejection 6d Pending May 04, 2023
18062871 BINDING MOLECULES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL MOSELEY II, NELSON B 1642 §112 Final Rejection 22d Pending Dec 07, 2022
17926283 METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES BRISTOL, LYNN ANNE 1643 §112 Non-Final OA 27d Pending Nov 18, 2022
17921042 TREATMENT OF CANCERS WITH AN ANTIBODY THAT BINDS LGR5 AND EGFR SHUPE, ELIZABETH A 1643 §103DP Non-Final OA 29d Pending Oct 24, 2022
17759728 MEANS AND METHOD FOR MODULATING IMMUNE CELL ENGAGING EFFECTS ALSOMAIRY, SARAH ABDOALATIF 1646 §103 Final Rejection — Pending Jul 29, 2022
17755196 MEANS AND METHODS FOR TREATING SUBJECTS WITH HER2 AND HER3 POSITIVE CANCER BRISTOL, LYNN ANNE 1643 §112 Non-Final OA 70d Pending Apr 22, 2022
17632181 TREATMENT OF CANCER WITH A COMBINATION OF AN ANTIBODY THAT BINDS LGR5 AND EGFR AND A TOPOISOMERASE I INHIBITOR MIDDLETON, DANAYA L 1674 §103§112DP Non-Final OA 28d Pending Feb 01, 2022
17431041 PRODUCING COMPOSITIONS COMPRISING TWO OR MORE ANTIBODIES FAUST, AMBER KATHLEEN 1643 §102§103§112 Non-Final OA — Pending Aug 13, 2021
17431044 COMBINATIONS OF BINDING MOIETIES THAT BIND EGFR, HER2 AND HER3 ALSOMAIRY, SARAH ABDOALATIF 1646 §103§112 Final Rejection 30d overdue Pending Aug 13, 2021

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