Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
26 pending office actions • 10 art units • 22 examiners • 0 of 26 (0%) have an AI response strategy ready • 28 patents granted in the last 365 days
Singular Genomics Systems Inc. currently manages 26 pending office actions within the Biotechnology & Pharmaceuticals technology area. This workload is distributed across 10 distinct art units, indicating a diverse range of technical subject matter within the portfolio. The company interacts with 22 distinct examiners, suggesting that prosecution strategies must be tailored to a variety of individual preferences and styles across the patent office.
The busiest examiner for this portfolio is LU, FRANK WEI MIN, who is responsible for 3 pending office actions. While the portfolio spans 10 distinct art units, the concentration of work under a single examiner represents a specific point of focus for the company's legal team. Managing 26 pending office actions across 22 distinct examiners requires a broad approach to patent prosecution to ensure consistency. This volume of filings highlights an active phase of intellectual property development for the firm.
Based on the USPTO statutory response window for each pending office action. 5 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 5 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §103 only | 6 (23%) |
| §112 only | 4 (15%) |
| Double-patenting + other | 3 (12%) |
| Multi-statute (no §101) | 13 (50%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| LU, FRANK WEI MIN | 3 | 62.7% | +67.7% |
| YU, TIAN NMN | 2 | 55.1% | +20.4% |
| KIM, YOUNG J | 2 | 64.8% | +18.1% |
| QIAN, CELINE X | 1 | 47.6% | +16.9% |
| ELHILO, EISA B | 1 | 83.0% | +16.2% |
| HERON, VELVET ELIZABETH | 1 | 47.4% | +52.6% |
| HAQ, SHAFIQUL | 1 | 64.8% | +55.2% |
| SISSON, BRADLEY L | 1 | 19.7% | +20.5% |
| WILDER, CYNTHIA B | 1 | 71.0% | +26.6% |
| MUMMERT, STEPHANIE KANE | 1 | 61.2% | +21.4% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18050688 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | CROW, ROBERT THOMAS | 97d overdue |
| 18364849 | COMPETITIVE METHODS AND COMPOSITIONS FOR AMPLIFYING POLYNUCLEOTIDES | TURPIN, ZACHARY MARK | 8d overdue |
| 17938254 | Polynucleotide Barcodes for Multiplexed Proteomics | BUNKER, AMY M | 4d overdue |
| 18915941 | PROXIMITY DETECTION OF BIOMOLECULE INTERACTIONS | SISSON, BRADLEY L | 13d |
| 18537266 | CONTROLLED ROLLING CIRCLE AMPLIFICATION | KIM, YOUNG J | 27d |
| 19345390 | ENCODING METHODS FOR MULTIPLEXED DETECTION OF TARGETS IN CELLS | QIAN, CELINE X | — |
| 19228533 | RHODAMINE FLUORESCENT COMPOUNDS AND METHODS OF USE THEREOF | ELHILO, EISA B | — |
| 19038150 | SOLID SUPPORTS USEFUL FOR TISSUE ADHERENCE | HERON, VELVET ELIZABETH | — |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18915941 | PROXIMITY DETECTION OF BIOMOLECULE INTERACTIONS | SISSON, BRADLEY L | 13d |
| 18537266 | CONTROLLED ROLLING CIRCLE AMPLIFICATION | KIM, YOUNG J | 27d |
| 19345390 | ENCODING METHODS FOR MULTIPLEXED DETECTION OF TARGETS IN CELLS | QIAN, CELINE X | — |
| 19344246 | METHODS FOR THREE-DIMENSIONAL NUCLEIC ACID SEQUENCING | LU, FRANK WEI MIN | — |
| 19228533 | RHODAMINE FLUORESCENT COMPOUNDS AND METHODS OF USE THEREOF | ELHILO, EISA B | — |
| 19038150 | SOLID SUPPORTS USEFUL FOR TISSUE ADHERENCE | HERON, VELVET ELIZABETH | — |
| 18959243 | ANALYZING CELL SAMPLES | HAQ, SHAFIQUL | — |
| 18812056 | METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES | WILDER, CYNTHIA B | — |
| Art Unit | Apps |
|---|---|
| 1681 | 6 |
| 1682 | 5 |
| 1683 | 3 |
| 1637 | 1 |
| 1798 | 1 |
| 1678 | 1 |
| 1693 | 1 |
| 1699 | 1 |
| 1677 | 1 |
| 1684 | 1 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19345390 | ENCODING METHODS FOR MULTIPLEXED DETECTION OF TARGETS IN CELLS | QIAN, CELINE X | 1637 | §103§112Other | Final Rejection | — | Pending | Sep 30, 2025 |
| 19344246 | METHODS FOR THREE-DIMENSIONAL NUCLEIC ACID SEQUENCING | LU, FRANK WEI MIN | 1683 | §112 | Non-Final OA | — | Pending | Sep 29, 2025 |
| 19228533 | RHODAMINE FLUORESCENT COMPOUNDS AND METHODS OF USE THEREOF | ELHILO, EISA B | — | §102§112 | Non-Final OA | — | Pending | Jun 04, 2025 |
| 19038150 | SOLID SUPPORTS USEFUL FOR TISSUE ADHERENCE | HERON, VELVET ELIZABETH | 1798 | §102§103 | Non-Final OA | — | Pending | Jan 27, 2025 |
| 18959243 | ANALYZING CELL SAMPLES | HAQ, SHAFIQUL | 1678 | §103§112 | Final Rejection | — | Pending | Nov 25, 2024 |
| 18915941 | PROXIMITY DETECTION OF BIOMOLECULE INTERACTIONS | SISSON, BRADLEY L | 1682 | §112 | Non-Final OA | 13d | Pending | Oct 15, 2024 |
| 18812056 | METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES | WILDER, CYNTHIA B | — | §112DP | Non-Final OA | — | Pending | Aug 22, 2024 |
| 18797131 | SPATIAL DETECTION OF CLONOTYPES IN TISSUES | MUMMERT, STEPHANIE KANE | 1681 | §102§103 | Non-Final OA | — | Pending | Aug 07, 2024 |
| 18679036 | PHOTOSTABLE DETECTABLE COMPOUNDS | XU, XIAOYUN | — | §103 | Non-Final OA | — | Pending | May 30, 2024 |
| 18704416 | MANIPULATING AND DETECTING BIOLOGICAL SAMPLES | YU, TIAN NMN | — | §102§103§112 | Non-Final OA | — | Pending | Apr 24, 2024 |
| 18592127 | METHODS FOR DIFFERENTIATING MODIFIED NUCLEOBASES | PRIEST, AARON A | — | §103 | Non-Final OA | — | Pending | Feb 29, 2024 |
| 18390463 | TARGETING OLIGONUCLEOTIDES AND METHODS OF USE THEREOF | KIM, YOUNG J | 1681 | §103§112 | Non-Final OA | — | Pending | Dec 20, 2023 |
| 18543979 | DISULFIDE CONTAINING THERAPEUTICS | GALSTER, SAMUEL LEONARD | 1693 | §103 | Non-Final OA | — | Pending | Dec 18, 2023 |
| 18537266 | CONTROLLED ROLLING CIRCLE AMPLIFICATION | KIM, YOUNG J | 1681 | §102§103§112 | Final Rejection | 27d | Pending | Dec 12, 2023 |
| 18537540 | LINKED TRANSCRIPT SEQUENCING | GOLDBERG, JEANINE ANNE | 1682 | §103DP | Non-Final OA | — | Pending | Dec 12, 2023 |
| 18507761 | AMPLIFICATION OLIGONUCLEOTIDES | GREENE, CAROLYN LEE | 1681 | §103§112 | Final Rejection | — | Pending | Nov 13, 2023 |
| 18490491 | MULTI-DIMENSIONAL POLYMER SCAFFOLDS FOR NUCLEIC ACID ANALYSES | WHATLEY, BENJAMIN R | 1699 | §102§103§112DP | Non-Final OA | — | Pending | Oct 19, 2023 |
| 18365476 | TETHERED DETECTION ASSAYS | EVANS, CHRISTOPHER RYAN | 1677 | §102§103§112 | Non-Final OA | — | Pending | Aug 04, 2023 |
| 18364849 | COMPETITIVE METHODS AND COMPOSITIONS FOR AMPLIFYING POLYNUCLEOTIDES | TURPIN, ZACHARY MARK | 1682 | §103§112 | Final Rejection | 8d overdue | Pending | Aug 03, 2023 |
| 18303468 | TARGETED SEQUENCING | HORLICK, KENNETH R | 1681 | §103 | Final Rejection | — | Pending | Apr 19, 2023 |
| 18069990 | STRAND DISPLACING SEQUENCING ENZYMES | LU, FRANK WEI MIN | 1683 | §112 | Non-Final OA | — | Pending | Dec 21, 2022 |
| 18069078 | PHASE PROTECTIVE REAGENT FLOW ORDERING | KENNEDY, SARAH JANE | 1682 | §103 | Final Rejection | — | Pending | Dec 20, 2022 |
| 18050688 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | CROW, ROBERT THOMAS | 1682 | §103§112 | Non-Final OA | 97d overdue | Pending | Oct 28, 2022 |
| 17938254 | Polynucleotide Barcodes for Multiplexed Proteomics | BUNKER, AMY M | 1684 | §102§103 | Final Rejection | 4d overdue | Pending | Oct 05, 2022 |
| 17938329 | METHODS FOR IN SITU PROTEOMICS | LU, FRANK WEI MIN | 1683 | §112 | Non-Final OA | — | Pending | Oct 05, 2022 |
| 17531488 | CONTACTLESS DETECTION OF AN ABERRANT CONDITION | YU, TIAN NMN | 1681 | §103 | Non-Final OA | — | Pending | Nov 19, 2021 |
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