Prosecution Insights
Last updated: July 17, 2026

The Wistar Institute

24 pending office actions • 13 art units • 23 examiners • 0 of 24 (0%) have an AI response strategy ready • 19 patents granted in the last 365 days

Portfolio Summary

24
Total Pending OAs
18
Non-Final OAs
5
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 15 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

10
Overdue
1
Due this week
1
Due this month
1
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 15 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (10)Due ≤ 7 days (1)Due ≤ 30 days (1)Due ≤ 60 days (1)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
9
Medium (38%)
7
Easy (29%)
8
Unknown (33%)

Rejection Statute Mix

BucketCases
§103 only7 (29%)
§102 only2 (8%)
§112 only5 (21%)
Double-patenting only2 (8%)
No statute on record8 (33%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

23
Life Sciences
96% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
4% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

240 h
Manual time on pending OAs
48 h
Time saved (low, 20%)
84 h
Time saved (mid, 35%)
2.1 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
GILL, RACHEL B 2 65.5% +28.0%
GURLEY, JAMI MICHELLE 1 50.0% +19.3%
EDGINGTONGIORDANO, FRANCESCA 1 72.3% +30.2%
LI, BAO Q 1 75.4% +26.4%
WANG, RUIXUE 1 56.2% +25.7%
BOESEN, AGNIESZKA 1 68.3% +21.8%
CORNELIUS, CLAIRE ADRIENNE 1 100.0% +0.0%
SWITZER, JULIET CAROLINE 1 42.0% +54.0%
BUCKMASTER, MARLENE VRENI 1 28.6% +77.1%
FOLEY, SHANON A 1 73.3% +18.0%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18552635 DNA Encoded Nanoparticle Vaccine Against Human Papillomavirus, and Methods of Use Thereof CORNELIUS, CLAIRE ADRIENNE

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18004964 DNA ANTIBODY CONSTRUCTS FOR USE AGAINST ROTAVIRUS BUCKMASTER, MARLENE VRENI

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18064482 LARGE AND SMALL T ANTIGENS OF MERKEL CELL POLYOMAVIRUS, NUCLEIC ACID CONSTRUCTS AND VACCINES MADE THEREFROM, AND METHODS OF USING SAME FOLEY, SHANON A 138d overdue
18588643 MAGE-A VACCINES AND METHODS OF TREATMENT USING THE SAME EDGINGTONGIORDANO, FRANCESCA 37d overdue
18251620 DNA ENCODED NANOPARTICLES AND METHOD OF USE THEREOF AS A CORONAVIRUS DISEASE 2019 (COVID-19) VACCINE GILL, RACHEL B 11d overdue
18042796 INTRADERMAL MERS-CoV VACCINE GILL, RACHEL B 12d
18407958 Extreme Polyvalency Induces Potent Cross-Clade Cellular and Humoral Responses in Rabbits and Non-human Primates LI, BAO Q 40d
18306548 COMPOSITIONS AND METHODS FOR DIAGNOSING LUNG CANCERS USING GENE EXPRESSION PROFILES SWITZER, JULIET CAROLINE 83d
18556414 GLYCAN MODIFIED SPIKE RECEPTOR BINDING DOMAIN NANOPARTICLES AND METHOD OF USE THEREOF AS A CORONAVIRUS DISEASE 2019 (COVID-19) VACCINE BOESEN, AGNIESZKA 84d
18699081 Novel Immune Cell Engagers For Immunotherapy GURLEY, JAMI MICHELLE

Top Art Units

Art UnitApps
1671 6
1672 4
1643 2
1622 2
1682 1
1635 1
1615 1
1647 1
1646 1
1633 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18699081 Novel Immune Cell Engagers For Immunotherapy GURLEY, JAMI MICHELLE Non-Final OA Pending Apr 05, 2024
18588643 MAGE-A VACCINES AND METHODS OF TREATMENT USING THE SAME EDGINGTONGIORDANO, FRANCESCA 1643 Other Non-Final OA 37d overdue Pending Feb 27, 2024
18407958 Extreme Polyvalency Induces Potent Cross-Clade Cellular and Humoral Responses in Rabbits and Non-human Primates LI, BAO Q 1671 §103 Non-Final OA 40d Pending Jan 09, 2024
18566859 SYNTHETIC DNA VACCINE IMMUNOGENIC IMPROVEMENTS WANG, RUIXUE 1672 §103 Non-Final OA Pending Dec 04, 2023
18556414 GLYCAN MODIFIED SPIKE RECEPTOR BINDING DOMAIN NANOPARTICLES AND METHOD OF USE THEREOF AS A CORONAVIRUS DISEASE 2019 (COVID-19) VACCINE BOESEN, AGNIESZKA 1672 DP Non-Final OA 84d Pending Oct 20, 2023
18552635 DNA Encoded Nanoparticle Vaccine Against Human Papillomavirus, and Methods of Use Thereof CORNELIUS, CLAIRE ADRIENNE 1672 §103 Non-Final OA Pending Sep 26, 2023
18251620 DNA ENCODED NANOPARTICLES AND METHOD OF USE THEREOF AS A CORONAVIRUS DISEASE 2019 (COVID-19) VACCINE GILL, RACHEL B 1671 Other Non-Final OA 11d overdue Pending May 03, 2023
18306548 COMPOSITIONS AND METHODS FOR DIAGNOSING LUNG CANCERS USING GENE EXPRESSION PROFILES SWITZER, JULIET CAROLINE 1682 Other Final Rejection 83d Pending Apr 25, 2023
18042796 INTRADERMAL MERS-CoV VACCINE GILL, RACHEL B 1671 §103 Non-Final OA 12d Pending Feb 24, 2023
18004964 DNA ANTIBODY CONSTRUCTS FOR USE AGAINST ROTAVIRUS BUCKMASTER, MARLENE VRENI 1672 §103 Final Rejection Pending Jan 10, 2023
18064482 LARGE AND SMALL T ANTIGENS OF MERKEL CELL POLYOMAVIRUS, NUCLEIC ACID CONSTRUCTS AND VACCINES MADE THEREFROM, AND METHODS OF USING SAME FOLEY, SHANON A 1671 Other Non-Final OA 138d overdue Pending Dec 12, 2022
18001116 CORONAVIRUS DISEASE 2019 (COVID-19) COMBINATION VACCINE STUART, CAREY ALEXANDER MC 1671 Other Non-Final OA 79d overdue Pending Dec 08, 2022
17995539 REAWAKENING OF DORMANT TUMOR CELLS BY MODIFIED LIPIDS DERIVED FROM STRESS ACTIVATED NEUTROPHILS KONOPKA, CATHERINE ANNE 1635 §103 Non-Final OA 182d overdue Pending Oct 05, 2022
17907697 Synthetic Soluble Receptor Mimics and Methods of Use for Treatment of COVID-19 ROSSI, JULIA ANNE LORRAIN 1615 Non-Final OA 167d overdue Pending Sep 29, 2022
17905143 TREATMENT OF CARM1-OVEREXPRESSING AND/OR ARID1A MUTANT CANCERS WITH IRE-1/XBP-1 INHIBITORS SIMMONS, CHRIS E 1622 §103 Non-Final OA Pending Aug 26, 2022
17759649 CD40-L BLOCKADE TO ENHANCE SYNTHETIC ANTIBODY THERAPY BUNNER, BRIDGET E 1647 §102 Non-Final OA Pending Jul 28, 2022
17787729 VACCINES AGAINST AFRICAN SWINE FEVER VIRUS, AND METHODS OF USING SAME SIFFORD, JEFFREY MARK 1671 Other Non-Final OA Pending Jun 21, 2022
17634968 NOVEL LOX-1 ANTIBODY COMPOSITIONS, LOX1 NEUTRALIZATION ASSAY AND METHODS OF TREATMENT USING SAME SHUPE, ELIZABETH A 1643 §112 Non-Final OA 162d overdue Pending Feb 12, 2022
17427434 DNA-ENCODED BISPECIFIC T-CELL ENGAGERS TARGETING CANCER ANTIGENS AND METHODS OF USE IN CANCER THERAPUTICS CUNNINGCHEN, KATHLEEN MARY 1646 DP Final Rejection Pending Jul 30, 2021
16973603 COMPOSITIONS AND METHODS FOR IN VIVO POST TRANSLATIONAL MODIFICATION POPA, ILEANA 1633 §112 Non-Final OA 17d overdue Pending Dec 09, 2020
16943947 Methods for Monitoring Polymorphonuclear Myeloid Derived Suppressor Cells and Compositions and Methods of Treatment of Cancer FORD, VANESSA L 1674 §112 Final Rejection 6d Pending Jul 30, 2020
16347861 DNA ANTIBODY CONSTRUCTS FOR USE AGAINST LYME DISEASE ZEMAN, ROBERT A 1645 §112 Non-Final OA 10d overdue Pending May 07, 2019
16098918 DNA Monoclonal Antibodies Targeting IL-6 and CD126 LEONARD, ARTHUR S 1631 §102 Final Rejection 31d overdue Pending Nov 05, 2018
18274514 Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease WARD, PAUL V 1622 §112 Non-Final OA Pending Jul 27, 2023

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